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Volumn 31, Issue 8, 2012, Pages 575-591

Synthesis, characterization, cellular uptake, apoptosis, cytotoxicity, dna-binding, and antioxidant activity studies of ruthenium(II) complexes

Author keywords

apoptosis; cellular uptake; cytotoxicity; DNA binding; Ruthenium complex

Indexed keywords

CISPLATIN; HYDROXYL RADICAL; RUTHENIUM COMPLEX; SINGLET OXYGEN;

EID: 84865791727     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770.2012.704110     Document Type: Article
Times cited : (15)

References (45)
  • 1
    • 0032538025 scopus 로고    scopus 로고
    • Sequence selective cleavage of a DNA octanucleotide by chlorinated bithiazoles and bleomycins [4]
    • DOI 10.1021/ja981937r
    • Zuber, G. Jr.; Quada, J.C.; Hecht, S.M. Sequence selective cleavage of a DNA octanucleotide by chlorinated bithiazoles and bleomycins. J. Am. Chem. Soc. 1998, 120, 9368-9369. (Pubitemid 28452714)
    • (1998) Journal of the American Chemical Society , vol.120 , Issue.36 , pp. 9368-9369
    • Zuber, G.1    Quada Jr., J.C.2    Hecht, S.M.3
  • 3
    • 17044392281 scopus 로고    scopus 로고
    • Synthesis crystal structure, cytotoxic activity and DNA-binding properties of the copper (II) and zinc (II) complexes with 1-[3- (2-pyridyl)pyrazol-1- ylmethyl]naphthalene
    • Zhang, H.; Liu, C.S.; Bu, X.H.; Yang, M. Synthesis, crystal structure, cytotoxic activity and DNA-binding properties of the copper (II) and zinc (II) complexes with 1-[3- (2-pyridyl)pyrazol-1- ylmethyl]naphthalene. J. Inorg. Biochem. 2005, 99, 1119-1125.
    • (2005) J. Inorg. Biochem , vol.99 , pp. 1119-1125
    • Zhang, H.1    Liu, C.S.2    Bu, X.H.3    Yang, M.4
  • 4
    • 20444434027 scopus 로고    scopus 로고
    • Effects of anthracene and pyrene units on the interactions of novel polypyridylruthenium(II) mixed-ligand complexes with DNA
    • DOI 10.1002/ejic.200400952
    • Mariappan, M.; Maiya, B.G. Effects of anthracene and pyrene units on the interactions of novel polypyridylruthenium (II) mixed-ligand complexes with DNA. Eur. J. Inorg. Chem. 2005, 11, 2164-2173. (Pubitemid 40831283)
    • (2005) European Journal of Inorganic Chemistry , Issue.11 , pp. 2164-2173
    • Mariappan, M.1    Maiya, B.G.2
  • 5
    • 79952281753 scopus 로고    scopus 로고
    • Synthesis DNA-binding and topoisomerase inhibitory activity of ruthenium (II) polypyridyl complexes
    • Du, K.J.; Wang, J.Q.; Kou, J.F.; Li, G.Y.; Wang, L.L.; Chao, H.; Ji, L.N. Synthesis, DNA-binding and topoisomerase inhibitory activity of ruthenium (II) polypyridyl complexes. Eur. J. Med. Chem. 2011, 46, 1056-1065.
    • (2011) Eur. J. Med. Chem , vol.46 , pp. 1056-1065
    • Du, K.J.1    Wang, J.Q.2    Kou, J.F.3    Li, G.Y.4    Wang, L.L.5    Chao, H.6    Ji, L.N.7
  • 6
    • 35848938474 scopus 로고    scopus 로고
    • Effects of anthracene and pyrene units on the interactions of novel polypyridylruthenium (II) mixed-ligand complexes with DNA
    • Brodie, C.R.; Aldrich-Wright, J.R. Effects of anthracene and pyrene units on the interactions of novel polypyridylruthenium (II) mixed-ligand complexes with DNA. Eur. J. Inorg. Chem. 2007, 30, 4781-4793.
    • (2007) Eur. J. Inorg. Chem , vol.30 , pp. 4781-4793
    • Brodie, C.R.1    Aldrich-Wright, J.R.2
  • 7
    • 32044436904 scopus 로고    scopus 로고
    • Synthesis, characterization, cytotoxic activities, and DNA-binding properties of the La(III) complex with Naringenin Schiff-base
    • DOI 10.1016/j.bmc.2005.10.031, PII S0968089605010187
    • Wang, B.D.; Yang, Z.Y.; Wang, Q.; Cai, T.K.; Crewdson, P. Synthesis, characterization, cytotoxic activities, and DNA-binding properties of the La (III) complex with naringenin Schiff-base. Bioorg. Med. Chem. 2006, 14, 1880-1888. (Pubitemid 43199520)
    • (2006) Bioorganic and Medicinal Chemistry , vol.14 , Issue.6 , pp. 1880-1888
    • Wang, B.-D.1    Yang, Z.-Y.2    Wang, Q.3    Cai, T.-K.4    Crewdson, P.5
  • 8
    • 3242666642 scopus 로고    scopus 로고
    • Dimeric 2,2-bipyridylruthenium (II) complexes containing 2,2-bis (1,2,4-triazin-3-yl)-4,4-bipyridine-like bridging ligands: Syntheses, characterization and DNA binding
    • Jiang, C.W. Dimeric 2,2-bipyridylruthenium (II) complexes containing 2,2-bis (1,2,4-triazin-3-yl)-4,4- bipyridine-like bridging ligands: syntheses, characterization and DNA binding. Eur. J. Inorg. Chem. 2004, 11, 2277-2282.
    • (2004) Eur. J. Inorg. Chem , vol.11 , pp. 2277-2282
    • Jiang, C.W.1
  • 9
    • 0034750973 scopus 로고    scopus 로고
    • Synthesis characterization, antioxidative and antitumor activities of solid quercetin rare earth (III) complexes
    • Zhou, J.; Wang, L.F.; Wang, J.Y.; Tang, N. Synthesis, characterization, antioxidative and antitumor activities of solid quercetin rare earth (III) complexes. J. Inorg. Biochem. 2001, 83, 41-48.
    • (2001) J. Inorg. Biochem , vol.83 , pp. 41-48
    • Zhou, J.1    Wang, L.F.2    Wang, J.Y.3    Tang, N.4
  • 10
    • 0014691619 scopus 로고
    • Platinum compounds: A new class of potent antitumor agents
    • Rosenberg, B.; VanCamp, L.; Trosko, J.E.;Mansour, V.H. Platinum compounds: a new class of potent antitumor agents. Nature 1969, 222, 385-386.
    • (1969) Nature , vol.222 , pp. 385-386
    • Rosenberg, B.1    Vancamp, L.2    Trosko, J.E.3    Mansour, V.H.4
  • 11
    • 37149008995 scopus 로고    scopus 로고
    • Ruthenium anticancer compounds: Challenges and expectations
    • Bratsos, I.; Jedner, S.; Gianferrara, T.; Alessio, E. Ruthenium anticancer compounds: challenges and expectations. Chimia 2007, 61, 692-697.
    • (2007) Chimia , vol.61 , pp. 692-697
    • Bratsos, I.1    Jedner, S.2    Gianferrara, T.3    Alessio, E.4
  • 13
    • 80052089927 scopus 로고    scopus 로고
    • Synthesis structures, cellular uptake and apoptosis-inducing properties of highly cytotoxic ruthenium-norharman complexes
    • Tan, C.P.; Wu, S.H.; Lai, S.S.; Wang, M.X.; Chen, Y.; Zhou, L.J.; Zhu, Y.P.; Lian, W.; Peng, W.L.; Ji, L.N.; Xu, A.L. Synthesis, structures, cellular uptake and apoptosis-inducing properties of highly cytotoxic ruthenium-norharman complexes. Dalton Trans. 2011, 40, 8611-8621.
    • (2011) Dalton Trans , vol.40 , pp. 8611-8621
    • Tan, C.P.1    Wu, S.H.2    Lai, S.S.3    Wang, M.X.4    Chen, Y.5    Zhou, L.J.6    Zhu, Y.P.7    Lian, W.8    Peng, W.L.9    Ji, L.N.10    Xu, A.L.11
  • 14
    • 84861444667 scopus 로고    scopus 로고
    • Spectral characteristics, DNA-binding and cytotoxicity of two functional Ru (II) mixed-ligand complexes
    • Tan, L.F.; Shen, J.L.; Liu, J.; Zeng, L.L.; Jin, L.H.;Weng, C. Spectral characteristics, DNA-binding and cytotoxicity of two functional Ru (II) mixed-ligand complexes. Dalton Trans. 2012, 41, 4575-4587.
    • (2012) Dalton Trans , vol.41 , pp. 4575-4587
    • Tan, L.F.1    Shen, J.L.2    Liu, J.3    Zeng, L.L.4    Jin, L.H.5    Weng, C.6
  • 15
    • 84856279815 scopus 로고    scopus 로고
    • Synthesis nucleic acid binding and cytotoxicity of oligonuclear ruthenium complexes containing labile ligands
    • Mulyana, Y.Y.; Collins, G.; Keene, R. Synthesis, nucleic acid binding and cytotoxicity of oligonuclear ruthenium complexes containing labile ligands. J. Incl. Phenom. Macrocycl. Chem. 2011, 71, 371-379.
    • (2011) J. Incl. Phenom. Macrocycl. Chem , vol.71 , pp. 371-379
    • Mulyana, Y.Y.1    Collins, G.2    Keene, R.3
  • 16
    • 73549089692 scopus 로고    scopus 로고
    • Synthesis DNA-binding, photocleavage, cytotoxicity and antioxidant activity of ruthenium (II) polypyridyl complexes
    • Liu, Y.J.; Zeng, C.H.; Huang, H.L.; He, L.X.; Wu, F.H. Synthesis, DNA-binding, photocleavage, cytotoxicity and antioxidant activity of ruthenium (II) polypyridyl complexes. Eur. J. Med. Chem. 2010, 45, 564-571.
    • (2010) Eur. J. Med. Chem , vol.45 , pp. 564-571
    • Liu, Y.J.1    Zeng, C.H.2    Huang, H.L.3    He, L.X.4    Wu, F.H.5
  • 17
    • 77954349732 scopus 로고    scopus 로고
    • Synthesis of ruthenium (II) complexes and characterization of their cytotoxicity in vitro, apoptosis,DNA-binding and antioxidant activity
    • Liu, Y.J.; Zeng, C.H.; Liang, Z.H.; Yao, J.H.; Huang, H.L.; Wu, F.H. Synthesis of ruthenium (II) complexes and characterization of their cytotoxicity in vitro, apoptosis,DNA-binding and antioxidant activity. Eur. J. Med. Chem. 2010, 45, 3087-3095.
    • (2010) Eur. J. Med. Chem , vol.45 , pp. 3087-3095
    • Liu, Y.J.1    Zeng, C.H.2    Liang, Z.H.3    Yao, J.H.4    Huang, H.L.5    Wu, F.H.6
  • 18
    • 80053506428 scopus 로고    scopus 로고
    • Cytotoxicity apoptosis, cellular uptake, cell cycle arrest, photocleavage and antioxidant activity of 1,10-phenanthroline ruthenium (II) complexes
    • Liu, Y.J.; Li, Z.Z.; Liang, Z.H.; Huang, H.L. Cytotoxicity, apoptosis, cellular uptake, cell cycle arrest, photocleavage and antioxidant activity of 1,10-phenanthroline ruthenium (II) complexes. DNA Cell Biol. 2011, 30, 839-848.
    • (2011) DNA Cell Biol , vol.30 , pp. 839-848
    • Liu, Y.J.1    Li, Z.Z.2    Liang, Z.H.3    Huang, H.L.4
  • 19
    • 85010439719 scopus 로고
    • A procedure for the isolation of deoxyribonucleic acid from micro-organisms
    • Marmur, J. A procedure for the isolation of deoxyribonucleic acid from micro-organisms. J. Mol. Biol. 1961, 3, 208-218.
    • (1961) J. Mol. Biol , vol.3 , pp. 208-218
    • Marmur, J.1
  • 20
    • 33947455249 scopus 로고
    • A further examination of the molecular weight and size of deoxypentose nucleic acid
    • Reichmann, M.E.; Rice, S.A.; Thomas, C.A.; Doty, P. A further examination of the molecular weight and size of deoxypentose nucleic acid. J. Am. Chem. Soc. 1954, 76, 3047-3053.
    • (1954) J. Am. Chem. Soc , vol.76 , pp. 3047-3053
    • Reichmann, M.E.1    Rice, S.A.2    Thomas, C.A.3    Doty, P.4
  • 21
    • 0041152495 scopus 로고
    • Mixed phosphine 2,2-bipyridine complexes of ruthenium
    • Sullivan, B.P.; Salmon, D.J.; Meyer, T.J. Mixed phosphine 2,2-bipyridine complexes of ruthenium. Inorg. Chem. 1978, 17, 3334-3341.
    • (1978) Inorg. Chem , vol.17 , pp. 3334-3341
    • Sullivan, B.P.1    Salmon, D.J.2    Meyer, T.J.3
  • 22
    • 0142057513 scopus 로고    scopus 로고
    • Carbazolefunctionalized europium complex and its high-efficiency organic electroluminescent properties
    • Xin, H.; Li, F.Y.; Guan, M.; Huang, C.H.; Sun, M.; Wang, K.Z.; Zhang, Y.A.; Jin, L.P. Carbazolefunctionalized europium complex and its high-efficiency organic electroluminescent properties. J. Appl. Phys. 2003, 94, 4729-4731.
    • (2003) J. Appl. Phys , vol.94 , pp. 4729-4731
    • Xin, H.1    Li, F.Y.2    Guan, M.3    Huang, C.H.4    Sun, M.5    Wang, K.Z.6    Zhang, Y.A.7    Jin, L.P.8
  • 23
    • 0023618205 scopus 로고
    • Polycyclic aromatic hydrocarbons physically intercalate into duplex regions of denatured DNA
    • DOI 10.1021/bi00394a013
    • Wolf, A.; Shimer, G.H. Jr.; Meehan, T. Polycyclic aromatic hydrocarbons physically intercalate into duplex regions of denatured DNA. Biochemistry 1987, 26, 6392-6396. (Pubitemid 17155512)
    • (1987) Biochemistry , vol.26 , Issue.20 , pp. 6392-6396
    • Wolfe, A.1    Shimer Jr., G.H.2    Meehan, T.3
  • 24
    • 0020452657 scopus 로고
    • Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: Equilibrium binding studies on interaction of daunomycin with deoxyribonucleic acid
    • DOI 10.1021/bi00260a005
    • Chaires, J.B.; Dattagupta, N.; Crothers, D.M. Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: equilibrium binding studies on the interaction of daunomycin with deoxyribonucleic acid. Biochemistry 1982, 21, 3933-3940. (Pubitemid 13237187)
    • (1982) Biochemistry , vol.21 , Issue.17 , pp. 3933-3940
    • Chaires, J.B.1    Dattagupta, N.2    Crothers, D.M.3
  • 25
    • 0027538012 scopus 로고
    • Tris(phenanthroline)ruthenium(II) enantiomer interactions with DNA: Mode and specificity of binding
    • Satyanarayana, S.; Dabrowiak, J.C.; Chaires, J.B. Tris (phenanthroline) ruthenium (II) enantiomer interactions with DNA: mode and specificity of binding. Biochemistry 1993, 32, 2573-2584. (Pubitemid 23090644)
    • (1993) Biochemistry , vol.32 , Issue.10 , pp. 2573-2584
    • Satyanarayana, S.1    Dabrowiak, J.C.2    Chaires, J.B.3
  • 26
    • 0026786133 scopus 로고
    • Neither- nor-tris (phenanthroline) ruthenium (II) binds to DNA by classical intercalation
    • Satyanaryana, S.; Dabrowial, J.C.; Chaires, J.B. Neither- nor-tris (phenanthroline) ruthenium (II) binds to DNA by classical intercalation. Biochemistry 1992, 31, 9319-9324.
    • (1992) Biochemistry , vol.31 , pp. 9319-9324
    • Satyanaryana, S.1    Dabrowial, J.C.2    Chaires, J.B.3
  • 27
    • 84984088862 scopus 로고
    • And sedimentation study of sonicated DNA-proflavine complexes
    • Cohen, G.; Eisenberg, H. Viscosity and sedimentation study of sonicated DNA-proflavine complexes. Biopolymers 1969, 8, 45-55.
    • (1969) Biopolymers , vol.8 , pp. 45-55
    • Cohen, G.1    Viscosity, E.H.2
  • 28
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65, 55-63. (Pubitemid 14203433)
    • (1983) Journal of Immunological Methods , vol.65 , Issue.1-2 , pp. 55-63
    • Mosmann, T.1
  • 30
    • 0026698173 scopus 로고
    • Apoptosis induced by anticancer drugs
    • Hickman, J.A. Apoptosis induced by anticancer drugs. Cancer Metast. Rev. 1992, 11, 121-139.
    • (1992) Cancer Metast. Rev , vol.11 , pp. 121-139
    • Hickman, J.A.1
  • 31
    • 0035840146 scopus 로고    scopus 로고
    • Interaction of [Ru (dmp)2 (dppz)]2+ and [Ru (dmb)2 (dppz)]2+ with DNA: Effects of the ancillary ligands on the DNA-binding behaviors
    • Liu, J.G.; Zhang, Q.L.; Shi, X.F.; Ji, L.N. Interaction of [Ru (dmp)2 (dppz)]2+ and [Ru (dmb)2 (dppz)]2+ with DNA: Effects of the ancillary ligands on the DNA-binding behaviors. Inorg. Chem. 2001, 40, 5045-5050.
    • (2001) Inorg. Chem , vol.40 , pp. 5045-5050
    • Liu, J.G.1    Zhang, Q.L.2    Shi, X.F.3    Ji, L.N.4
  • 32
    • 78149281390 scopus 로고    scopus 로고
    • DNA-binding antioxidant activity and in vitro cytotoxicity induced by ruthenium (II) complexes containing polypyridyl ligands
    • Zeng, C.H.; Liu, Y.J.; Li, Z.Z.; Liang, Z.H.; Huang, H.L.; Wu, F.H. DNA-binding, antioxidant activity and in vitro cytotoxicity induced by ruthenium (II) complexes containing polypyridyl ligands. Transition Met. Chem. 2010, 35, 731-736.
    • (2010) Transition Met. Chem , vol.35 , pp. 731-736
    • Zeng, C.H.1    Liu, Y.J.2    Li, Z.Z.3    Liang, Z.H.4    Huang, H.L.5    Wu, F.H.6
  • 33
    • 62749102801 scopus 로고    scopus 로고
    • Synthesis and DNA-binding studies of two ruthenium (II) complexes of an intercalating ligand
    • Arockiasamy, D.L.; Radhika, S.; Parthasarathi, R.; Nair, B.N. Synthesis and DNA-binding studies of two ruthenium (II) complexes of an intercalating ligand. Eur. J. Med. Chem. 2009, 44, 2044-2051.
    • (2009) Eur. J. Med. Chem , vol.44 , pp. 2044-2051
    • Arockiasamy, D.L.1    Radhika, S.2    Parthasarathi, R.3    Nair, B.N.4
  • 34
    • 81255184289 scopus 로고    scopus 로고
    • Thermodynamic and structural study of phenanthroline derivative ruthenium complex/DNA interactions: Probing partial intercalation and binding properties
    • Grueso, E.; Lopez-Pérez, G.; Castellano, M.; Prado-Gotor, R. Thermodynamic and structural study of phenanthroline derivative ruthenium complex/DNA interactions: probing partial intercalation and binding properties. J. Inorg. Biochem. 2012, 106, 1-9.
    • (2012) J. Inorg. Biochem , vol.106 , pp. 1-9
    • Grueso, E.1    Lopez-Pérez, G.2    Castellano, M.3    Prado-Gotor, R.4
  • 36
    • 0031127338 scopus 로고    scopus 로고
    • Comparative study of Ru (bpz)3 2+ Ru (bipy)3 2+ and Ru (bpz)2Cl2 as photosensitizers of DNA cleavage and adduct formation
    • Vicendo, P.; Mouysset, S.; Paillous, N. Comparative study of Ru (bpz)3 2+ Ru (bipy)3 2+ and Ru (bpz)2Cl2 as photosensitizers of DNA cleavage and adduct formation. Photochem. Photobiol. 1997, 65, 647-655.
    • (1997) Photochem. Photobiol , vol.65 , pp. 647-655
    • Vicendo, P.1    Mouysset, S.2    Paillous, N.3
  • 38
    • 0019331875 scopus 로고
    • Role of superoxide in deoxyribonucleic acid strand scission
    • Lesko, S.A.; Lorentzen, R.J.; Ts'o, P.O. Role of superoxide in deoxyribonucleic acid strand scission. Biochemistry 1980, 19, 3023-3028.
    • (1980) Biochemistry , vol.19 , pp. 3023-3028
    • Lesko, S.A.1    Lorentzen, R.J.2    Ts'o, P.O.3
  • 39
    • 0015386420 scopus 로고
    • Unambiguous evidence for the participation of single oxygen (1) in photodynamic oxidation of amino acid
    • Nilsson, R.; Merkel, P.B.; Kearns, D.R. Unambiguous evidence for the participation of single oxygen (1) in photodynamic oxidation of amino acid. Photochem. Photobiol. 1972, 16, 117-124.
    • (1972) Photochem. Photobiol , vol.16 , pp. 117-124
    • Nilsson, R.1    Merkel, P.B.2    Kearns, D.R.3
  • 40
    • 33846084199 scopus 로고    scopus 로고
    • Synthesis, crystal structure, DNA binding and photo-induced DNA cleavage activity of (S-methyl-l-cysteine)copper(II) complexes of heterocyclic bases
    • DOI 10.1016/j.jinorgbio.2006.09.018, PII S0162013406002777
    • Patra, A.K.; Nethaji, M.; Chakravarty, A.R. Synthesis, crystal structure, DNA binding and photoinduced DNA cleavage activity of (S-methyl-L-cysteine) copper (II) complexes of heterocyclic bases. J. Inorg. Biochem. 2007, 101, 233-244. (Pubitemid 46074152)
    • (2007) Journal of Inorganic Biochemistry , vol.101 , Issue.2 , pp. 233-244
    • Patra, A.K.1    Nethaji, M.2    Chakravarty, A.R.3
  • 42
    • 58149359129 scopus 로고    scopus 로고
    • DNA binding, photocleavage, and topoisomerase inhibition of functionalized ruthenium (II)-polypyridine complexes
    • Gao, F.; Chao, H.; Ji, L.N. DNA binding, photocleavage, and topoisomerase inhibition of functionalized ruthenium (II)-polypyridine complexes. Chem. Biodivers. 2008, 5, 1962-1979.
    • (2008) Chem. Biodivers , vol.5 , pp. 1962-1979
    • Gao, F.1    Chao, H.2    Ji, L.N.3
  • 43
    • 0035581422 scopus 로고    scopus 로고
    • Oxidative DNA damage in human peripheral leukocytes induced by massive aerobic exercise
    • DOI 10.1016/S0891-5849(01)00729-8, PII S0891584901007298
    • Tsai, K.; Hsu, T.G.; Hsu, K.M.; Cheng, H.; Liu, T.Y.; Hsu, C.F.; Kong, C.W. Oxidative DNA damage in human peripheral leukocytes induced by massive aerobic exercise. Free Radical. Biol. Med. 2001, 31, 1465-1472. (Pubitemid 33145317)
    • (2001) Free Radical Biology and Medicine , vol.31 , Issue.11 , pp. 1465-1472
    • Tsai, K.1    Hsu, T.-G.2    Hsu, K.-M.3    Cheng, H.4    Liu, T.-Y.5    Hsu, C.-F.6    Kong, C.-W.7
  • 45
    • 77952388630 scopus 로고    scopus 로고
    • In vitro cytotoxicity, apoptosis, DNA-binding, and antioxidant activity studies of ruthenium (II) complexes
    • Huang, H.L.; Liu, Y.J.; Zeng, C.H.; He, L.X.; Wu, F.H. In vitro cytotoxicity, apoptosis, DNA-binding, and antioxidant activity studies of ruthenium (II) complexes. DNA Cell Biol. 2010, 29, 261-270.
    • (2010) DNA Cell Biol , vol.29 , pp. 261-270
    • Huang, H.L.1    Liu, Y.J.2    Zeng, C.H.3    He, L.X.4    Wu, F.H.5


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