Vitamin D3 enhances ATRA-mediated neurosteroid biosynthesis in human glioma GI-1 cells

Journal of Biochemistry

Volumn 152, Issue 3, 2012, Pages 285-292

  Yagishita, Toshiaki ^a   Kushida, Akira ^a   Tamura, Hiroomi ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

ATRA; CYP11A1; glia; neurosteroid; vitamin D

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; CALCIPOTRIOL; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); COLECALCIFEROL; COLECALCIFEROL RECEPTOR; NEUROSTEROID; PROGESTERONE; RETINOIC ACID;

ARTICLE; BRAIN NERVE CELL; DRUG POTENTIATION; GENE EXPRESSION; GENE INDUCTION; GLIOMA CELL; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; STEROIDOGENESIS;

BIOSYNTHETIC PATHWAYS; CELL LINE, TUMOR; CHOLECALCIFEROL; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; MALE; MIDDLE AGED; NEURONS; NEUROTRANSMITTER AGENTS; PARACRINE COMMUNICATION; TRANSCRIPTIONAL ACTIVATION; TRETINOIN;

EID: 84865789752     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvs074     Document Type: Article

References (42)

1. Bouillon, R., Carmeliet, G., Verlinden, L., van Etten, E., Verstuyf, A., Luderer, H.F., Lieben, L., Mathieu, C, and Demay, M. (2008) Vitamin D and human health: lessons from vitamin D receptor null mice. Endocrine Rev. 29, 726-776
2. Heaney, R.P. (2008) Vitamin D in health and disease. Clin. Am. Soc. Nephrol. 3, 1535-1541
3. Zittermann, A. (2003) VitaminD in preventive medicine: are we ignoring the evidence? Br. J. Nutr. 89, 552-572
4. Kesby, J.P., Eyles, D.W., Burne, T.H., and McGrath, J.J. (2011) The effects of vitamin D on brain development and adult brain function. Mol. Cell. Endocrinol. 347, 121-127
5. 3 receptors in the central nervous system of the rat embryo. Brain Res. 804, 193-205
6. Kalueff, A.V. and Touhimaa, P. (2007) Neurosteroid hormone vitamin D and its utility in clinical nutrition. Curr. Opin. Clin. Metab. Care 10, 12-19
7. Annweiler, C, Allali, G, Allain, P., Bridenbaugh, S., Schott, A.M., Kressig, R.W., and Beauchet, O. (2009) Vitamin D and cognitive performance in adults: a systematic review. Eur. J. Neurol. 16, 1083-1089
8. McGrath, J.J., Burne, T.H., Feron, F., Mackay-Sim, A., and Eyles, D.W. (2010) Developmental vitamin D deficiency and risk of schizophrenia: a 10-year update. Schizophr. Bull. 36, 1073-1078
9. Baulieu, E.E. (1997) Neurosteroids: of the nervous system, by the nervous system, for the nervous system. Recent Prog. Horm. Res. 52, 1-32
10. Baulieu, E.E. (1998) Neurosteroids: a novel function of the brain. Psychoneuroendocrinology 23, 963-987
11. Compagnone, N.A. and Mellon, S.H. (2000) Neurosteroids: Biosynthesis and function of these novel neuromodulators. Front. Neuroendocrinol. 21, 1-58
12. Stoffel-Wagner, B. (2001) Neurosteroid metabolism in the human brain. Eur. J. Endocrinol. 145, 660-679
13. Sanne, J.L. and Krueger, K.F. (1995) Expression of cyto-chrome P450 side-chain cleavage enzyme and 3β-hyd-roxysteroid dehydrogenase in the rat central nervous system: a study by polymerase chain reaction and in situ hybridization. J. Neurochem. 65, 528-536
14. Kohchi, C, Ukena, K., and Tsutsui, K. (1998) Age-and region-specific expressions of the messenger RNAs encoding for steroidogenic enzymes p450scc, P450c17 and 3β-HSD in the postnatal rat brain. Brain Res. 801, 233-238
15. Tsutsui, K., Ukena, K., Takase, M., Kohchi, C, and Lea, R.W. (1999) Neurosteroid biosynthesis in vertebrate brains. Comp. Biochem. Physiol. C 124, 121-129
16. Guennoun, R., Fiddes, R.J., Gouezou, M., Lombes, M., and Baulieu, E.E. (1995) A key enzyme in the biosynthesis of neurosteroids, 3β-hydroxysteroid dehydrogenase/Δ 5-Δ 4-isomerase (3β-HSD), is expressed in rat brain. Mol. Brain Res. 30, 287-300
17. Tsutsui, K, Sakamaoto, H., and Ukena, K. (2003) Novel aspect of the cerebellum: biosynthesis of neurosteroids in the Purkinje cell. Cerebellum 2, 215-222
18. Hu, Z.Y., Bourreau, E., Jung-Testas, I., Robel, P., and Baulieu, E.E. (1987) Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone. Proc. Natl Acad. Sci. USA 84, 8215-8219
19. Hu, Z.Y., Bourreau, E., Jung-Testas, I., Robel, P., and Baulieu, E.E. (1987) Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone. Proc. Natl Acad. Sci. USA 84, 8215-8219
20. Kushida, A. and Tamura, H. (2009) Retinoic acids induce neurosteroid biosynthesis in human glial GI-1 Cells via the induction of steroidogenic genes. J. Biochem. 146, 917-923
21. Higuchi, R., Fockler, C, Dollinger, G, and Watson, R. (1993) Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Biotechnology 11, 1026-1030
22. Zhu, S.T. and Glaser, M. (2008) Regulatory role of cyto-chrome P450scc and pregnenolone in myelination by rat Schwann cells. Mol. Cell. Biochem. 313, 79-89
23. Issa, L.L., Leong, G.M., Barry, J.B., Sutherland, R.L., and Eisman, J.A. (2001) Glucocorticoid receptor-interacting protein-1 and receptor-associated coactiva-tor-3 differentially interact with the vitamin D receptor (VDR) and regulate VDR-retinoid X receptor transcrip-tional cross-talk. Endocrinology 142, 1606-1615
24. Bouchard, P., Chabbert-Buffet, N., and Fauser, B.C. (2011) Selective progesterone receptor modulators in reproductive medicine: pharmacology, clinical efficacy and safety. Fertil. Steril. 96, 1175-1189
25. Arce, J.C., Balen, A., Platteau, P., Pettersson, G., and Andersen, A.N. (2011) Mid-luteal progesterone concentrations are associated with live birth rates during ovu-lation induction. Reprod. Biomed. Online 22, 449-456
26. Langub, M.C., Herman, J.P., Malluche, H.H., and Koszewsk, N.J. (2001) Evidence of functional vitamin D receptors in rat hippocampus. Neuroscience 104, 49-56
27. Prufer, K., Veenstra, T.D., Jirikowski, G.F., and Kumar, R. (1999) Distribution of 1, 25-dihydroxyvitamin D3 receptor immunoreactivity in the rat brain and spinal cord. J. Chem. Immunol. 16, 135-145
28. Kalueff, A.V., Lou, Y.R., Laaksi, I., and Tuohimaa, P. (2004) Increased anxiety in mice lacking vitamin D receptor gene. Neuroreport 15, 1271-1274
29. Kalueff, A.V., Lou, Y.R., Laaksi, I., and Tuohimaa, P. (2004) Increased grooming behavior in mice lacking vitamin D receptors. Physiol. Behav. 15, 405-409
30. Harms, L.R., Burne, T.H., Eyles, D.W., and McGrath, J.J. (2011) Vitamin D and the brain. Best Pract. Res. Clin. Endocrinol. Metab. 25, 657-669
31. van Broekhoven, F. and Verkes, R.J. (2003) Neurosteroids in depression: a review. Psychopharmacol-ogy 165, 97-110
32. Evatt, M.L., Delong, M.R., Khazai, N., Rosen, A., Triche, S., and Tangpricha, V. (2008) Prevalence of vitamin D insufficiency in patients with Parkinson disease and Alzheimer's disease. Arch. Neurol. 65, 1348-1352
33. Orlov, I., Rochel, N., Moras, D., and Klaholz, B.P. (2011) Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA. EMBO J. 31, 291-300
34. Zhang, P., Rodriguez, H., and Mellon, S.H. (1995) Transcriptional regulation of P450scc gene expression in neural and steroidogenic cells: implications for regulation of neurosteroidogenesis. Mol. Endocrinol. 9, 1571-1582
35. Chiang, Y.F., Lin, H.T., Hu, J.W., Tai, Y.C., Lin, Y.C., and Hu, M.C. (2011) Differential regulation of the human CYP11A1 promoter in mouse brain and adrenals. J. Cell Physiol. 226, 1998-2005
36. Espallergues, J., Givalois, L., Temsamani, J., Laruelle, C, and Maurice, T. (2009) The 3beta-hydroxysteroid dehydrogenase inhibitor trilostane shows antidepressant properties in mice. Psychoneuroendocrinology 34, 644-659
37. Zheng, P. (2009) Neuroactive steroid regulation of neurotransmitter release in the CNS: action, mechanism and possible significance. Prog. Neurobiol. 89, 134-152
38. Stein, D.G, Wright, D.W., and Kellermann, A.L. (2008) Does progesterone have neuroprotective properties? Ann. Emerg. Med. 51, 164-172
39. De Nicola, A.F., Labombarda, F., Deniselle, M.C, Gonzalez, S.L., Garay, L., Meyer, M., Gargiulo, G, Guennoun, R., and Schumacher, M. (2009) Progesterone neuroprotection in traumatic CNS injury and moto-neuron degeneration. Front Neuroendocrinol. 30, 173-187
40. Schumacher, M., Guennoun, R., Robert, F., Carelli, C, Gago, N, Ghoumari, A., Gonzalez Deniselle, M.C, Gonzalez, S.L., Ibanez, C, Labombarda, F., Coirini, H., Baulieu, E.E., and De Nicola, A.F. (2004) Local synthesis and dual actions of progesterone in the nervous system: neuroprotection and myelination. Growth Horm. IGF Res. 14 (Suppl. A), 18-33
41. Gonzalez, S.L., Labombarda, F., Gonzalez Deniselle, M.C, Guennoun, R., Schumacher, M., and De Nicola, A.F. (2004) Progesterone up-regulates neuronal brain-derived neurotrophic factor expression in the injured spinal cord. Neuroscience 125, 605-614
42. Kalueff, A.V., Lou, Y.R., Laaksi, I., and Tuohimaa, P. (2004) Impaired motor performance in mice lacking neurosteroid vitamin D receptors. Brain Res. Bull. 64, 25-29