Developmental vitamin D deficiency and risk of schizophrenia: A 10-year update

Schizophrenia Bulletin

Volumn 36, Issue 6, 2010, Pages 1073-1078

  McGrath, John J ^a,b   Burne, Thomas H ^a,b   Féron, François ^c   MacKay Sim, Allan ^d   Eyles, Darryl W ^a,b  

^a Queensland Center for Mental Health Research   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c Mediterranée University   (France)

^d GRIFFITH UNIVERSITY   (Australia)

Author keywords

Animal models; Epidemiology; Neurodevelopment; Prevention; Schizophrenia; Vitamin D

Indexed keywords

COLECALCIFEROL; VITAMIN D RECEPTOR;

AFRICAN AMERICAN; ARTICLE; BRAIN FUNCTION; CELL DIFFERENTIATION; CELL PROLIFERATION; ECOLOGY; EUROPE; HUMAN; NONHUMAN; PRIORITY JOURNAL; SCANDINAVIA; SCHIZOPHRENIA; THIRD TRIMESTER PREGNANCY; ULTRAVIOLET B RADIATION; UNITED KINGDOM; VITAMIN D DEFICIENCY;

ANIMALS; AUSTRALIA; BRAIN; DISEASE MODELS, ANIMAL; ENVIRONMENT; FEMALE; GEOGRAPHY; HUMANS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PREVALENCE; RISK FACTORS; RURAL POPULATION; SCHIZOPHRENIA; SEASONS; URBAN POPULATION; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 78649638175     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbq101     Document Type: Article

References (65)

1. McGrath JJ. The surprisingly rich contours of schizophrenia epidemiology. Arch Gen Psychiatry. 2007;64:14-16.
2. McGrath J. Hypothesis: is low prenatal vitamin D a risk modifying factor for schizophrenia? Schizophr Res. 1999;40:173-177.
3. Burkert R, McGrath J, Eyles DW. Vitamin D receptor expressionin the embryonic rat brain. Neurosci Res Commun. 2003;33:63-71.
4. Harms LR, Eyles DW, McGrath JJ, Mackay-Sim A, BurneTH. Developmental vitamin D deficiency alters adult behaviour in 129/SvJ and C57BL/6J mice. Behav Brain Res. 2008;187:343-350.
5. Burne TH, Féron F, Brown J, Eyles DW, McGrath JJ, Mackay-Sim A. Combined prenatal and chronic postnatal vitamin D deficiency in rats impairs prepulse inhibition of acousticstartle. Physiol Behav. 2004;81:651-655.
6. Holick MF, Chen TC. Vitamin D deficiency: a world wide problem with health consequences. Am J Clin Nutr. 2008;87:1080S-1086S.
7. Looker AC, Dawson-Hughes B, Calvo MS, Gunter EW, Sahyoun NR. Serum 25-hydroxy vitamin D status of adolescentsand adults in two seasonal subpopulations from NHANES III. Bone. 2002;30:771-777.
8. Lips P. Worldwide status of vitamin D nutrition. J Steroid Biochem Mol Biol. 2010;121:297-300.
9. van der Meer IM, Middelkoop BJ, Boeke AJ, Lips P. Prevalence of vitamin D deficiency among Turkish, Moroccan, Indian and sub-Sahara African populations in Europeand their countries of origin: an overview [published onlineahead of print May 12, 2010]. Osteoporos Int. PMID:20461360.
10. Hintzpeter B, Scheidt-Nave C, Muller MJ, Schenk L, Mensink GB. Higher prevalence of vitamin D deficiency isassociated with immigrant background among children andadolescents in Germany. J Nutr. 2008;138:1482-1490.
11. Mithal A, Wahl DA, Bonjour JP, et al. Global vitamin D statusand determinants of hypovitaminosis D. Osteoporos Int. 2009;20:1807-1820.
12. Rejnmark L, Jorgensen ME, Pedersen MB, et al. Vitamin Dinsufficiency in Greenlanders on a westernized fare: ethnicdifferences in calcitropic hormones between Greenlandersand Danes. Calcif Tissue Int. 2004;74:255-263.
13. Lips P. Vitamin D status and nutrition in Europe and Asia. J Steroid Biochem Mol Biol. 2007;103:620-625.
14. Holick MF. Environmental factors that influence thecutaneous production of vitamin D. Am J Clin Nutr. 1995;61(suppl 3):638S-645S.
15. Torrey EF, Miller J, Rawlings R, Yolken RH. Seasonality of births in schizophrenia and bipolar disorder: a review of theliterature. Schizophr Res. 1997;28:1-38.
16. Davies G, Welham J, Chant D, Torrey EF, McGrath J. Asystematic review and meta-analysis of Northern Hemisphereseason of birth studies in schizophrenia. Schizophr Bull. 2003;29:587-593.
17. Saha S, Chant DC, Welham JL, McGrath JJ. The incidenceand prevalence of schizophrenia varies with latitude. Acta Psychiatr Scand. 2006;114:36-39.
18. Kinney DK, Teixeira P, Hsu D, et al. Relation of schizophreniaprevalence to latitude, climate, fish consumption, infant mortality, and skin color: a role for prenatal vitamin D deficiency and infections? Schizophr Bull. 2009;35:582-595.
19. Pile WJ. A study of the correlation between dementia praecoxand the month of birth. Va Med Mon. 1951;78:438-440.
20. Moskovitz RA. Seasonality in schizophrenia. Lancet. 1978;1:664.
21. McGrath J, Saha S, Welham J, El Saadi O, MacCauley C, Chant D. A systematic review of the incidence of schizophrenia:the distribution of rates and the influence of sex, urbanicity, migrant status and methodology. BMC Med. 2004;2:13.
22. Cantor-Graae E, Selten JP. Schizophrenia and migration:a meta-analysis and review. Am J Psychiatry. 2005;162:12-24.
23. Dealberto MJ. Ethnic origin and increased risk for schizophreniain immigrants to recent and traditional countries of immigration. Acta Psychiatr Scand. 2010.
24. McGrath J, Scott J. Urban birth and risk of schizophrenia:a worrying example of epidemiology where the data are strongerthan the hypotheses. Epidemiol Psychiatr Soc. 2006;15:243-246.
25. Marcelis M, Takei N, van Os J. Urbanization and risk forschizophrenia: does the effect operate before or around thetime of illness onset? Psychol Med. 1999;29:1197-1203.
26. Mortensen PB, Pedersen CB, Westergaard T, et al. Effects offamily history and place and season of birth on the risk of schizophrenia. N Engl J Med. 1999;340:603-608.
27. March D, Hatch SL, Morgan C, et al. Psychosis and place. Epidemiol Rev. 2008;30:84-100.
28. Eyles DW, Smith S, Kinobe R, Hewison M, McGrath JJ. Distribution of the vitamin D receptor and 1 alpha-hydroxylasein human brain. J Chem Neuroanat. 2005;29:21-30.
29. Cui X, McGrath JJ, Burne TH, Mackay-Sim A, Eyles DW. Maternal vitamin D depletion alters neurogenesis in the developingrat brain. Int J Dev Neurosci. 2007;25:227-232.
30. Brown J, Bianco JI, McGrath JJ, Eyles DW. 1, 25-Dihydroxyvitamin D(3) induces nerve growth factor, promotes neuriteoutgrowth and inhibits mitosis in embryonic rat hippocampalneurons. Neurosci Lett. 2003;343:139-143.
31. Eyles D, Brown J, Mackay-Sim A, McGrath J, Féron F. Vitamin D3 and brain development. Neuroscience. 2003;118:641-653.
32. Ko P, Burkert R, McGrath J, Eyles D. Maternal vitamin D(3)deprivation and the regulation of apoptosis and cell cycle duringrat brain development. Brain Res Dev Brain Res. 2004;153:61-68.
33. Féron F, Burne TH, Brown J, et al. Developmental vitamin D3 deficiency alters the adult rat brain. Brain Res Bull. 2005;65:141-148.
34. Almeras L, Eyles D, Benech P, et al. Developmental vitamin D deficiency alters brain protein expression in the adult rat:implications for neuropsychiatric disorders. Proteomics. 2007;7:769-780. (Pubitemid 46450654)
35. Eyles D, Almeras L, Benech P, et al. Developmental vitamin D deficiency alters the expression of genes encoding mitochondrial, cytoskeletal and synaptic proteins in the adult ratbrain. J Steroid Biochem Mol Biol. 2007;103:538-545.
36. McGrath J, Iwazaki T, Eyles D, et al. Protein expression inthe nucleus accumbens of rats exposed to developmental vitamin D deficiency. PLoS ONE. 2008;3:e2383.
37. Burne TH, Becker A, Brown J, Eyles DW, Mackay-Sim A, McGrath JJ. Transient prenatal vitamin D deficiency is associatedwith hyperlocomotion in adult rats. Behav Brain Res. 2004;154:549-555.
38. Kesby JP, Burne TH, McGrath JJ, Eyles DW. Developmentalvitamin D deficiency alters MK 801-induced hyperlocomotionin the adult rat: an animal model of schizophrenia. Biol Psychiatry. 2006;60:591-596.
39. O'Loan J, Eyles DW, Kesby J, Ko P, McGrath JJ, Burne TH. Vitamin D deficiency during various stages of pregnancy inthe rat; its impact on development and behaviour in adult offspring. Psychoneuroendocrinology. 2007;32:227-234.
40. Kesby JP, Cui X, O'Loan J, McGrath JJ, Burne TH, Eyles DW. Developmental vitamin D deficiency alters dopamine-mediated behaviors and dopamine transporter functionin adult female rats. Psychopharmacology (Berl). 2010;208:159-168.
41. Kesby JP, Cui X, Ko P, McGrath JJ, Burne TH, Eyles DW. Developmental vitamin D deficiency alters dopamine turnoverin neonatal rat forebrain. Neurosci Lett. 2009;461:155-158.
42. Becker A, Eyles DW, McGrath JJ, Grecksch G. Transientprenatal vitamin D deficiency is associated with subtle alterationsin learning and memory functions in adult rats. Behav Brain Res. 2005;161:306-312.
43. Abreu DA, Nivet E, Baril N, Khrestchatisky M, Roman F, Féron F. Developmental vitamin D deficiency alters learningin C57BL/6J mice. Behav Brain Res. 2010.
44. Grecksch G, Ruthrich H, Hollt V, Becker A. Transient prenatalvitamin D deficiency is associated with changes of synapticplasticity in the dentate gyrus in adult rats. Psychoneuroendocrinology. 2009;34(suppl 1):S258-S264.
45. McGrath J, Eyles D, Mowry B, Yolken R, Buka S. Lowmaternal vitamin D as a risk factor for schizophrenia: a pilotstudy using banked sera. Schizophr Res. 2003;63:73-78.
46. Eyles D, Anderson C, Ko P, et al. A sensitive LC/MS/MS assayof 25OH vitamin D3 and 25OH vitamin D2 in driedblood spots. Clin Chim Acta. 2009;403:145-151.
47. Eyles DW, Morley R, Anderson C, et al. The utility of neonataldried blood spots for the assessment of neonatal vitamin Dstatus. Paediatr Perinat Epidemiol. 2010;24:303-308.
48. McGrath JJ, Eyles DW, Pedersen CB, et al. Neonatal vitamin D status and risk of schizophrenia: a population-based casecontrolstudy. Arch Gen Psychiatry. In press.
49. McGrath JJ, Saha S, Burne TH, Eyles DW. A systematic review of the association between common single nucleotide polymorphisms and 25-hydroxy vitamin D concentrations. J Steroid Biochem Mol Biol. 2010.
50. Dror DK, Allen LH. Vitamin D inadequacy in pregnancy: biology, outcomes, and interventions. Nutr Rev. 2010;68:465-477.
51. McGrath J, Saari K, Hakko H, et al. Vitamin D supplementationduring the first year of life and risk of schizophrenia: a Finnish birth-cohort study. Schizophr Res. 2004;67: 237-245.
52. Annweiler C, Allali G, Allain P, et al. Vitamin D and cognitiveperformance in adults: a systematic review. Eur J Neurol. 2009;16: 1083-1089.
53. Wang JY, Wu JN, Cherng TL, et al. Vitamin D(3) attenuates 6-hydroxydopamine-induced neurotoxicity in rats. Brain Res. 2001;904: 67-75.
54. Brewer LD, Thibault V, Chen KC, Langub MC, LandfieldPW, Porter NM. Vitamin D hormone confers neuroprotectionin parallel with downregulation of L-type calcium channelexpression in hippocampal neurons. J Neurosci. 2001;21: 98-108.
55. McCann JC, Ames BN. Is there convincing biological or behavioralevidence linking vitamin D deficiency to brain dysfunction? FASEB J. 2008;22: 982-1001.
56. Kajta M, Makarewicz D, Zieminska E, et al. Neuroprotectionby co-treatment and post-treating with calcitriol followingthe ischemic and excitotoxic insult in vivo and in vitro. Neurochem Int. 2009;55: 265-274.
57. Moore ME, Piazza A, McCartney Y, Lynch MA. Evidencethat vitamin D3 reverses age-related inflammatorychanges in the rat hippocampus. Biochem Soc Trans. 2005;33(pt 4): 573-577.
58. Selten JP, Cantor-Graae E. Social defeat: risk factor forschizophrenia? Br J Psychiatry. 2005;187: 101-102.
59. Obradovic D, Gronemeyer H, Lutz B, Rein T. Cross-talkof vitamin D and glucocorticoids in hippocampal cells. J Neurochem. 2006;96: 500-509.
60. Amminger GP, Schafer MR, Papageorgiou K, et al. Longchainomega-3 fatty acids for indicated prevention of psychoticdisorders: a randomized, placebo-controlled trial. Arch Gen Psychiatry. 2010;67: 146-154.
61. McGrath J. Is it time to trial vitamin D supplements for the prevention of schizophrenia? Acta Psychiatr Scand. 2010; Inpress.
62. Davey Smith G. Reflections on the limitations to epidemiology. J Clin Epidemiol. 2001;54: 325-331.
63. Editorial. A decade for psychiatric disorders. Nature. 2010;463: 9.
64. McGrath JJ, Selten JP. Mental health: don't overlook environmentand its risk factors. Nature. 2008;454: 824.
65. McGrath JJ, Richards LJ. Why schizophrenia epidemiologyneeds neurobiology-and vice versa. Schizophr Bull. 2009;35: 577-581.