A negative ion mass spectrometry approach to identify cross-linked peptides utilizing characteristic disulfide fragmentations

Journal of the American Society for Mass Spectrometry

Volumn 23, Issue 8, 2012, Pages 1364-1375

  Calabrese, Antonio N ^a   Good, Nikki J ^a   Wang, Tianfang ^a   He, Jingjia ^a   Bowie, John H ^a   Pukala, Tara L ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Chemical cross linking; Disulfide fragmentations; Negative ion mass spectrometry; Protein structure determination

Indexed keywords

ANALYTICAL TOOL; CHEMICAL CROSS-LINKING; CROSS-LINKING REAGENTS; DISULFIDE BONDS; DISULFIDE FRAGMENTATIONS; FRAGMENTATION BEHAVIOR; HIGH THROUGHPUT; ION MASS SPECTROMETRY; PROTEIN COMPLEXES; PROTEIN STRUCTURES; PROTEOLYTIC FRAGMENTS; SPECIFIC LOCATION; UBIQUITIN;

COVALENT BONDS; CROSSLINKING; MASS SPECTROMETRY; NEGATIVE IONS;

PEPTIDES;

CYSTINE; DISULFIDE; DITHIOBIS(SUCCINIMIDYL)PROPIONATE; PROPIONIC ACID DERIVATIVE; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; DISULFIDE BOND; FRAGMENTATION REACTION; IONIZATION; MASS SPECTROMETRY; MOLECULAR INTERACTION; MOLECULAR MODEL; PEPTIDE ANALYSIS; PROTEIN CLEAVAGE; PROTEIN CROSS LINKING; QUANTUM YIELD; RESIDUE ANALYSIS; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; CATTLE; CROSS-LINKING REAGENTS; DISULFIDES; MASS SPECTROMETRY; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; THERMODYNAMICS; UBIQUITIN;

EID: 84865739315     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-012-0407-x     Document Type: Article

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