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Volumn 65, Issue 9, 2012, Pages 807-812

LRP1 gene polymorphisms are associated with premature risk of cardiovascular disease in patients with familial hypercholesterolemia;Los polimorfismos del gen LRP1 se asocian al riesgo prematuro de enfermedad cardiovascular en pacientes con hipercolesterolemia familiar

Author keywords

Cardiovascular disease; Heterozygous familial hypercholesterolemia; LRP1 gene; Polymorphisms

Indexed keywords

LOW DENSITY LIPOPROTEIN RECEPTOR;

EID: 84865702301     PISSN: 03008932     EISSN: 15792242     Source Type: Journal    
DOI: 10.1016/j.recesp.2012.03.013     Document Type: Article
Times cited : (18)

References (26)
  • 2
    • 0029091696 scopus 로고
    • Coronary artery disease in heterozygous familial hypercholesterolemia patients with the same LDL receptor gene mutation
    • J. Ferrieres, J. Lambert, Lussier-Cacan, and J. Davignon Coronary artery disease in heterozygous familial hypercholesterolemia patients with the same LDL receptor gene mutation Circulation 92 1995 290 295
    • (1995) Circulation , vol.92 , pp. 290-295
    • Ferrieres, J.1    Lambert, J.2    Lussier-Cacan3    Davignon, J.4
  • 4
    • 78649262505 scopus 로고    scopus 로고
    • Uso de la genética y la transcriptómica en el diagnóstico y tratamiento de la enfermedad coronaria
    • J.E. Freedman, and H.F. Lafrati Uso de la genética y la transcriptómica en el diagnóstico y tratamiento de la enfermedad coronaria Rev Esp Cardiol 63 2010 1123 1126
    • (2010) Rev Esp Cardiol , vol.63 , pp. 1123-1126
    • Freedman, J.E.1    Lafrati, H.F.2
  • 5
    • 0037058838 scopus 로고    scopus 로고
    • Low- density lipoprotein upregulates low-density lipoprotein receptor-related protein expression in vascular smooth muscle cells: Possible involvement of sterol regulatory element binding protein-2-dependent mechanism
    • V. Llorente-Cortés, M. Otero-Viñas, S. Sánchez, C. Rodríguez, and L. Badimon Low- density lipoprotein upregulates low-density lipoprotein receptor-related protein expression in vascular smooth muscle cells: possible involvement of sterol regulatory element binding protein-2-dependent mechanism Circulation 106 2002 3104 3110
    • (2002) Circulation , vol.106 , pp. 3104-3110
    • Llorente-Cortés, V.1    Otero-Viñas, M.2    Sánchez, S.3    Rodríguez, C.4    Badimon, L.5
  • 6
    • 0028210044 scopus 로고
    • Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and scavenger receptor in human atherosclerotic lesions
    • J. Luoma, T. Hiltunen, T. Särkioja, S.K. Moestrup, J. Gliemann, and T. Kodama Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and scavenger receptor in human atherosclerotic lesions J Clin Invest 93 1994 2014 2021
    • (1994) J Clin Invest , vol.93 , pp. 2014-2021
    • Luoma, J.1    Hiltunen, T.2    Särkioja, T.3    Moestrup, S.K.4    Gliemann, J.5    Kodama, T.6
  • 7
    • 0031827759 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein in atherosclerosis development: Up-regulation of gene expression in patients with coronary obstruction
    • K. Handschug, S. Schulz, C. Schnurer, S. Kohler, K. Wenzel, and W. Teichmann Low-density lipoprotein receptor-related protein in atherosclerosis development: up-regulation of gene expression in patients with coronary obstruction J Mol Med 76 1998 596 600
    • (1998) J Mol Med , vol.76 , pp. 596-600
    • Handschug, K.1    Schulz, S.2    Schnurer, C.3    Kohler, S.4    Wenzel, K.5    Teichmann, W.6
  • 8
    • 18544391404 scopus 로고    scopus 로고
    • The LDL receptor-related protein (LRP1/A2MR) and coronary atherosclerosis - Novel genomic variants and functional consequences
    • S. Schulz, U. Schagdarsurengin, P. Greiser, G. Birkenmeier, U. Muller-Werdan, and M. Hagemann The LDL receptor-related protein (LRP1/A2MR) and coronary atherosclerosis - novel genomic variants and functional consequences Hum Mutat 20 2002 404
    • (2002) Hum Mutat , vol.20 , pp. 404
    • Schulz, S.1    Schagdarsurengin, U.2    Greiser, P.3    Birkenmeier, G.4    Muller-Werdan, U.5    Hagemann, M.6
  • 9
    • 14644439259 scopus 로고    scopus 로고
    • LDL receptor-related protein and the vascular wall: Implications for atherothrombosis
    • V. Llorente-Cortes, and L. Badimon LDL receptor-related protein and the vascular wall: implications for atherothrombosis Arterioscler Thromb Vasc Biol 25 2005 497 504
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 497-504
    • Llorente-Cortes, V.1    Badimon, L.2
  • 11
    • 72649097483 scopus 로고    scopus 로고
    • Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism
    • S. Mosig, K. Rennert, P. Büttner, S. Krause, D. Lütjohann, and M. Soufi Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism BMC Medical Genomics 1 2008 60
    • (2008) BMC Medical Genomics , vol.1 , pp. 60
    • Mosig, S.1    Rennert, K.2    Büttner, P.3    Krause, S.4    Lütjohann, D.5    Soufi, M.6
  • 12
    • 52049109169 scopus 로고    scopus 로고
    • Cardiovascular disease in familial hypercholesterolaemia: Influence of low-density lipoprotein receptor mutation type and classic risk factors
    • Spanish Familial Hypercholesterolemia Group
    • R. Alonso, N. Mata, S. Castillo, F. Fuentes, P. Saenz, O. Muñiz Spanish Familial Hypercholesterolemia Group Cardiovascular disease in familial hypercholesterolaemia: influence of low-density lipoprotein receptor mutation type and classic risk factors Atherosclerosis 200 2008 315 322
    • (2008) Atherosclerosis , vol.200 , pp. 315-322
    • Alonso, R.1    Mata, N.2    Castillo, S.3    Fuentes, F.4    Saenz, P.5    Muñiz, O.6
  • 13
    • 79958166529 scopus 로고    scopus 로고
    • Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART)
    • N. Mata, R. Alonso, L. Badimón, T. Padró, F. Fuentes, and O. Muñiz Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART) Lipids Health Dis 10 2011 94
    • (2011) Lipids Health Dis , vol.10 , pp. 94
    • Mata, N.1    Alonso, R.2    Badimón, L.3    Padró, T.4    Fuentes, F.5    Muñiz, O.6
  • 14
    • 24144475212 scopus 로고    scopus 로고
    • Spanish Familial Hypercholesterolemia Group. Tendon xanthomas in familial hypercholesterolemia are associated with cardiovascular risk independently of the low-density lipoprotein receptor gene mutation
    • F. Civeira, S. Castillo, R. Alonso, E. Meriño-Ibarra, A. Cenarro, and M. Artied Spanish Familial Hypercholesterolemia Group. Tendon xanthomas in familial hypercholesterolemia are associated with cardiovascular risk independently of the low-density lipoprotein receptor gene mutation Arterioscler Thromb Vasc Biol 25 2005 1960 1965
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1960-1965
    • Civeira, F.1    Castillo, S.2    Alonso, R.3    Meriño-Ibarra, E.4    Cenarro, A.5    Artied, M.6
  • 15
    • 0035864651 scopus 로고    scopus 로고
    • Sequencing of the coding exons of the LRP1 and LDLR genes on individual DNA samples reveals novel mutations in both genes
    • F. Van Leuven, E. Thiry, M. Lambrechts, L. Stas, T. Boon, and K. Bruynseels Sequencing of the coding exons of the LRP1 and LDLR genes on individual DNA samples reveals novel mutations in both genes Atherosclerosis 154 2001 567 577
    • (2001) Atherosclerosis , vol.154 , pp. 567-577
    • Van Leuven, F.1    Thiry, E.2    Lambrechts, M.3    Stas, L.4    Boon, T.5    Bruynseels, K.6
  • 16
    • 3543148440 scopus 로고    scopus 로고
    • Genetic and functional characteristics of the human in vivo LRP1/A2MR receptor suggested as a risk marker for Alzheimer's disease and other complex (degenerative) diseases
    • C. Glaser, S. Schulz, K. Handschug, K. Huse, and G. Birkenmeier Genetic and functional characteristics of the human in vivo LRP1/A2MR receptor suggested as a risk marker for Alzheimer's disease and other complex (degenerative) diseases Neurosci Res 50 2005 85 101
    • (2005) Neurosci Res , vol.50 , pp. 85-101
    • Glaser, C.1    Schulz, S.2    Handschug, K.3    Huse, K.4    Birkenmeier, G.5
  • 17
    • 33747827929 scopus 로고    scopus 로고
    • SNPStats: A web tool for the analysis of association studies
    • X. Solé, E. Guino, J. Valls, R. Iniesta, and V. Moren SNPStats: a web tool for the analysis of association studies Bioinformatics 22 2006 1928 1929
    • (2006) Bioinformatics , vol.22 , pp. 1928-1929
    • Solé, X.1    Guino, E.2    Valls, J.3    Iniesta, R.4    Moren, V.5
  • 18
    • 79958236829 scopus 로고    scopus 로고
    • Estrategias para la elaboración de modelos estadísticos de regresión
    • E. Núñez, E.W. Steyerberg, and J. Núñez Estrategias para la elaboración de modelos estadísticos de regresión Rev Esp Cardiol 64 2011 501 507
    • (2011) Rev Esp Cardiol , vol.64 , pp. 501-507
    • Núñez, E.1    Steyerberg, E.W.2    Núñez, J.3
  • 19
    • 2342591299 scopus 로고    scopus 로고
    • Large scale association analysis for identification of genes underlying premature coronary heart disease: Cumulative perspective from analysis of 111 candidate genes
    • GeneQuest Investigators
    • J.J. McCarthy, A. Parker, R. Salem, D.J. Moliterno, Q. Wang, E.F. Plow GeneQuest Investigators Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes J Med Genet 41 2004 334 341
    • (2004) J Med Genet , vol.41 , pp. 334-341
    • McCarthy, J.J.1    Parker, A.2    Salem, R.3    Moliterno, D.J.4    Wang, Q.5    Plow, E.F.6
  • 20
    • 0038742040 scopus 로고    scopus 로고
    • Influence of exonic polymorphisms in the gene for LDL receptor-related protein (LRP) on risk of coronary artery disease
    • A. Pocathikorn, B. Granath, E. Thiry, F. Van Leuven, R. Taylor, and C. Mamotte Influence of exonic polymorphisms in the gene for LDL receptor-related protein (LRP) on risk of coronary artery disease Atherosclerosis 168 2003 115 121
    • (2003) Atherosclerosis , vol.168 , pp. 115-121
    • Pocathikorn, A.1    Granath, B.2    Thiry, E.3    Van Leuven, F.4    Taylor, R.5    Mamotte, C.6
  • 21
    • 0035071487 scopus 로고    scopus 로고
    • The C667T low-density lipoprotein receptor related protein polymorphism and coronary artery disease, plasma lipoproteins, and longevity in the Czech population
    • P. Benes, J. Muzik, J. Benedik, E. Lubomir, A. Vasku, and S. Lenska The C667T low-density lipoprotein receptor related protein polymorphism and coronary artery disease, plasma lipoproteins, and longevity in the Czech population J Mol Med 79 2001 116 120
    • (2001) J Mol Med , vol.79 , pp. 116-120
    • Benes, P.1    Muzik, J.2    Benedik, J.3    Lubomir, E.4    Vasku, A.5    Lenska, S.6
  • 22
    • 33748775185 scopus 로고    scopus 로고
    • Contribution of low density lipoprotein receptor-related protein genotypes to coagulation factor VIII levels in thrombotic women
    • G. Marchetti, B. Lunghi, C. Legnani, M. Cini, M. Pinotti, and F. Mascoli Contribution of low density lipoprotein receptor-related protein genotypes to coagulation factor VIII levels in thrombotic women Haematologica 91 2006 1261 1263
    • (2006) Haematologica , vol.91 , pp. 1261-1263
    • Marchetti, G.1    Lunghi, B.2    Legnani, C.3    Cini, M.4    Pinotti, M.5    Mascoli, F.6
  • 23
    • 34247602603 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein 1 polymorphism 663C>T affects clotting factor VIII activity and increases the risk of venous thromboembolism
    • R. Vormitag, P. Bencur, C. Ay, T. Tengler, T. Vukovich, and P. Quehenberger Low-density lipoprotein receptor-related protein 1 polymorphism 663C>T affects clotting factor VIII activity and increases the risk of venous thromboembolism J Thromb Haemost 5 2007 497 502
    • (2007) J Thromb Haemost , vol.5 , pp. 497-502
    • Vormitag, R.1    Bencur, P.2    Ay, C.3    Tengler, T.4    Vukovich, T.5    Quehenberger, P.6
  • 24
    • 29144495242 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein polymorphisms in patients with elevated factor VIII coagulant activity and venous thrombosis
    • N. Cunningham, M.A. Laffan, R.A. Manning, and J.S. O'Donnell Low-density lipoprotein receptor-related protein polymorphisms in patients with elevated factor VIII coagulant activity and venous thrombosis Blood Coagul Fibrinolysis 16 2005 465 468
    • (2005) Blood Coagul Fibrinolysis , vol.16 , pp. 465-468
    • Cunningham, N.1    Laffan, M.A.2    Manning, R.A.3    O'Donnell, J.S.4
  • 25
    • 79960698030 scopus 로고    scopus 로고
    • Genetic variability within cholesterol lowering pathway and the effectiveness of statins in reducing the risk of MI
    • B. Peters, H. Pett, O. Klungel, B. Stricker, B. Psaty, and N. Glazer Genetic variability within cholesterol lowering pathway and the effectiveness of statins in reducing the risk of MI Atherosclerosis 217 2011 458 464
    • (2011) Atherosclerosis , vol.217 , pp. 458-464
    • Peters, B.1    Pett, H.2    Klungel, O.3    Stricker, B.4    Psaty, B.5    Glazer, N.6


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