Role of microRNA-21 and programmed cell death 4 in the pathogenesis of human uterine leiomyomas

Fertility and Sterility

Volumn 98, Issue 3, 2012, Pages

  Fitzgerald, J Browning ^a   Chennathukuzhi, Vargheese ^a   Koohestani, Faezeh ^b   Nowak, Romana A ^b   Christenson, Lane K ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Leiomyoma; microRNA; miR 21; PDCD 4; uterine fibroids

Indexed keywords

CASPASE 3; ELONGATION FACTOR 2; MICRORNA 21; PROGRAMMED CELL DEATH 4 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; CANCER GROWTH; CELL IMMORTALIZATION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MENSTRUAL CYCLE; MYOMETRIUM; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA TRANSLATION; UNIVERSITY HOSPITAL; UTERUS MYOMA;

EID: 84865694062     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2012.05.040     Document Type: Article

References (38)

1. D. Day Baird, D.B. Dunson, M.C. Hill, D. Cousins, and J.M. Schectman High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence Am J Obstet Gynecol 188 2003 100 107
2. C.M. Farquhar, and C.A. Steiner Hysterectomy rates in the United States 1990-1997 Obstet Gynecol 99 2002 229 234
3. D. Brandon, C. Bethea, E. Strawn, M. Novy, K. Burry, and M. Harrington Progesterone receptor messenger ribonucleic acid and protein are overexpressed in human uterine leiomyomas Am J Obstet Gynecol 169 1993 78 85
4. E.A. Stewart, and A.J. Friedman Steroidal treatment of myomas: preoperative and long-term medical therapy Sem Reprod Endocrinol 10 1992 344 357
5. F. Sato, M. Mori, M. Nishi, R. Kudo, and H. Miyake Familial aggregation of uterine myomas in Japanese women J Epidemiol 12 2002 249 253
6. R. Luoto, J. Kaprio, E.M. Rutanen, P. Taipale, M. Perola, and M. Koskenvuo Heritability and risk factors of uterine fibroids - the Finnish Twin Cohort study Maturitas 37 2000 15 26
7. A. Esquela-Kerscher, and F.J. Slack Oncomirs - microRNAs with a role in cancer Nat Rev Cancer 6 2006 259 269
8. A.M. Krichevsky, and G. Gabriely miR-21: a small multi-faceted RNA J Cell Mol Med 13 2009 39 53
9. E.E. Marsh, Z. Lin, P. Yin, M. Milad, D. Chakravarti, and S.E. Bulun Differential expression of microRNA species in human uterine leiomyoma versus normal myometrium Fertil Steril 89 2008 1771 1776
10. Q. Pan, X. Luo, and N. Chegini In focus: differential expression of microRNAs in myometrium and leiomyomas and regulation by ovarian steroids J Cell Mol Med 12 2008 227 240
11. T. Wang, X. Zhang, L. Obijuru, J. Laser, V. Aris, and P. Lee A micro RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas Genes Chromosomes Cancer 46 2007 336 347
12. L.B. Frankel, N.R. Christoffersen, A. Jacobsen, M. Lindow, A. Krogh, and A.H. Lund Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells J Biol Chem 283 2008 1026 1033
13. B. Lankat-Buttgereit, and R. Goke The tumour suppressor Pdcd4: recent advances in the elucidation of function and regulation Biol Cell 101 2009 309 317
14. B. Lankat-Buttgereit, C. Gregel, A. Knolle, A. Hasilik, R. Arnold, and R. Goke Pdcd4 inhibits growth of tumor cells by suppression of carbonic anhydrase type II Mol Cell Endocrinol 214 2004 149 153
15. A.P. Jansen, C.E. Camalier, and N.H. Colburn Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis Cancer Res 65 2005 6034 6041
16. N. Wei, S.S. Liu, K.K.L. Chan, and H.Y.S. Ngan Tumour suppressive function and modulation of programmed cell death 4 (PDCD4) in ovarian cancer PloS One 7 2012 e30311
17. Q. Pan, X. Luo, and N. Chegini microRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cells Mol Hum Reprod 16 2010 215 227
18. M.M. Grudzien, P.S. Low, P.C. Manning, M. Arredondo, R.J. Belton, and R.A. Nowak The antifibrotic drug halofuginone inhibits proliferation and collagen production by human leiomyoma and myometrial smooth muscle cells Fertil Steril 93 2010 1290 1298
19. A.G. Ryazanov, E.A. Shestakova, and P.G. Natapov Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation Nature 334 1988 170 173
20. J. Condon, S. Yin, B. Mayhew, R. Word, W. Wright, and J. Shay Telomerase immortalization of human myometrial cells Biol Reprod 67 2002 506 514
21. S.D. Fiedler, M.Z. Carletti, and L.K. Christenson Quantitative RT-PCR methods for mature microRNA expression analysis Methods Mol Biol 630 2010 49 64
22. A.G. Ryazanov, and E.K. Davydova Mechanism of elongation factor 2 (EF-2) inactivation upon phosphorylation phosphorylated EF-2 is unable to catalyze translocation FEBS Lett 251 1989 187 190
23. M.R. Young, A.N. Santhanam, N. Yoshikawa, and N.H. Colburn Have tumor suppressor PDCD4 and its counteragent oncogenic miR-21 gone rogue? Mol Interv 10 2010 76 79
24. J.S. Crabtree, S.A. Jelinsky, H.A. Harris, S.E. Choe, M.M. Cotreau, and M.L. Kimberland Comparison of human and rat uterine leiomyomata: identification of a dysregulated mammalian target of rapamycin pathway Cancer Res 69 2009 6171 6178
25. H.S. Yang, A.P. Jansen, A.A. Komar, X. Zheng, W.C. Merrick, and S. Costes The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation Mol Cell Biol 23 2003 26 37
26. T. Schmid, M.M. Bajer, J.S. Blees, L.K. Eifler, L. Milke, and D. Rübsamen Inflammation-induced loss of Pdcd4 is mediated by phosphorylation-dependent degradation Carcinogenesis 32 2011 1427 1433
27. H. Allgayer Pdcd4, a colon cancer prognostic that is regulated by a microRNA Crit Rev Oncol Hematol 73 2010 185 191
28. Z. Lu, M. Liu, V. Stribinskis, C. Klinge, K. Ramos, and N. Colburn MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene Oncogene 27 2008 4373 4379
29. I. Asangani, S. Rasheed, D. Nikolova, J. Leupold, N. Colburn, and S. Post MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer Oncogene 27 2007 2128 2136
30. M. Si, S. Zhu, H. Wu, Z. Lu, F. Wu, and Y. Mo miR-21-mediated tumor growth Oncogene 26 2007 2799 2803
31. Y. Cheng, R. Ji, J. Yue, J. Yang, X. Liu, and H. Chen MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy? Am J Pathol 170 2007 1831 1840
32. S. Zhu, H. Wu, F. Wu, D. Nie, S. Sheng, and Y.Y. Mo MicroRNA-21 targets tumor suppressor genes in invasion and metastasis Cell Res 18 2008 350 359
33. O. Kurachi, H. Matsuo, T. Samoto, and T. Maruo Tumor necrosis factor-α expression in human uterine leiomyoma and its down-regulation by progesterone J Clin Endocrinol Metab 86 2001 2275 2280
34. X. Wu, A. Blanck, M. Olovsson, B. Möller, R. Favini, and B. Lindblom Apoptosis, cellular proliferation and expression of p53 in human uterine leiomyomas and myometrium during the menstrual cycle and after menopause Acta Obstet Gynecol Scand 79 2000 397 404
35. T. Maruo, H. Matsuo, T. Samoto, Y. Shimomura, O. Kurachi, and Z. Gao Effects of progesterone on uterine leiomyoma growth and apoptosis Steroids 65 2000 585 592
36. T. Maruo, N. Ohara, J. Wang, and H. Matsuo Sex steroidal regulation of uterine leiomyoma growth and apoptosis Hum Reprod Update 10 2004 207 220
37. A. Makker, M.M. Goel, V. Das, and A. Agarwal PI3K-Akt-mTOR and MAPK signaling pathways in polycystic ovarian syndrome, uterine leiomyomas and endometriosis: an update Gynecol Endocrinol 28 2011 175 181
38. X.J. Yin, G. Wang, and F.S. Khan-Dawood Requirements of phosphatidylinositol-3 kinase and mammalian target of rapamycin for estrogen-induced proliferation in uterine leiomyoma-and myometrium-derived cell lines Am J Obstet Gynecol 196 2007 176.e1 176.e5