Vascular endothelial growth factor gene polymorphisms and colorectal cancer risk: A meta-analysis

Genetics and Molecular Research

Volumn 10, Issue 4, 2011, Pages 3674-3688

  Zhou, L P ^a   Luan, H ^a   Dong, X H ^a   Jin, G J ^a   Man, D L ^a   Shang, H ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Colorectal cancer; Meta analysis; Polymorphism; VEGF

Indexed keywords

VASCULOTROPIN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; COLORECTAL CANCER; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; VASCULAR ENDOTHELIAL GROWTH FACTOR GENE; CLASSIFICATION; COLORECTAL TUMOR; ETHNOLOGY; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; MALE; META ANALYSIS; MIDDLE AGED; PUBLISHING; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL;

COLORECTAL NEOPLASMS; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PUBLICATION BIAS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84865653761     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/2011.October.31.13     Document Type: Article

References (40)

1. Bae SJ, Kim JW, Kang H, Hwang SG, et al. (2008). Gender-specific association between polymorphism of vascular endothelial growth factor (VEGF 936 C>T) gene and colon cancer in Korea. Anticancer Res. 28: 1271-1276.
2. Brogan IJ, Khan N, Isaac K, Hutchinson JA, et al. (1999). Novel polymorphisms in the promoter and 5' UTR regions of the human vascular endothelial growth factor gene. Hum. Immunol. 60: 1245-1249.
3. Cacev T, Loncar B, Seiwerth S, Spavanti S, et al. (2008). Vascular endothelial growth factor polymorphisms-1154 G/A and-460 C/T are not associated with VEGF mRNA expression and susceptibility to sporadic colon cancer. DNA Cell Biol. 27: 569-574.
4. Cao C, Ying T, Fang JJ, Sun SF, et al. (2010). Polymorphism of vascular endothelial growth factor-2578C/A with cancer risk: evidence from 11263 subjects. Med. Oncol. [Ahead of print].
5. Carmeliet P and Jain RK (2000). Angiogenesis in cancer and other diseases. Nature 407: 249-257.
6. Chae YS, Kim JG, Sohn SK, Cho YY, et al. (2008). Association of vascular endothelial growth factor gene polymorphisms with susceptibility and clinicopathologic characteristics of colorectal cancer. J. Korean Med. Sci. 23: 421-427.
7. Clapper ML (2000). Genetic polymorphism and cancer risk. Curr. Oncol. Rep. 2: 251-256.
8. Dassoulas K, Gazouli M, Rizos S, Theodoropoulos G, et al. (2009). Common polymorphisms in the vascular endothelial growth factor gene and colorectal cancer development, prognosis, and survival. Mol. Carcinog. 48: 563-569.
9. Des Guetz G, Uzzan B, Nicolas P, Cucherat M, et al. (2006). Microvessel density and VEGF expression are prognostic factors in colorectal cancer. Meta-analysis of the literature. Br. J. Cancer 94: 1823-1832.
10. Duthie SJ (2011). Epigenetic modifications and human pathologies: cancer and CVD. Proc. Nutr. Soc. 70: 47-56.
11. Ferrara N (1999). Molecular and biological properties of vascular endothelial growth factor. J. Mol. Med. 77: 527-543.
12. Ferrara N (2000). Vascular endothelial growth factor and the regulation of angiogenesis. Recent. Prog. Horm. Res. 55: 15-35.
13. Folkman J and Shing Y (1992). Angiogenesis. J. Biol. Chem. 267: 10931-10934.
14. Gasparini G, Toi M, Gion M, Verderio P, et al. (1997). Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma. J. Natl. Cancer Inst. 89: 139-147.
15. Hanahan D and Folkman J (1996). Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364.
16. Higgins JP and Thompson SG (2002). Quantifying heterogeneity in a meta-analysis. Stat. Med. 21: 1539-1558.
17. Hofmann G, Langsenlehner U, Renner W, Langsenlehner T, et al. (2008). Common single nucleotide polymorphisms in the vascular endothelial growth factor gene and colorectal cancer risk. J. Cancer Res. Clin. Oncol. 134: 591-595.
18. Knight JC (2005). Regulatory polymorphisms underlying complex disease traits. J. Mol. Med. 83: 97-109.
19. Kuramochi H, Hayashi K, Uchida K, Miyakura S, et al. (2006). Vascular endothelial growth factor messenger RNA expression level is preserved in liver metastases compared with corresponding primary colorectal cancer. Clin. Cancer Res. 12: 29-33.
20. Liu L, Liu L, Zeng F, Wang K, et al. (2010). Meta-analysis of the association between VEGF-634 G>C and risk of malignancy based on 23 case-control studies. J. Cancer Res. Clin. Oncol. 137: 1027-1036.
21. Maltese P, Canestrari E, Ruzzo A, Graziano F, et al. (2009). VEGF gene polymorphisms and susceptibility to colorectal cancer disease in Italian population. Int. J. Colorectal Dis. 24: 165-170.
22. Park HM, Hong SH, Kim JW, Oh D, et al. (2007). Gender-specific association of the VEGF-2578C > A polymorphism in Korean patients with colon cancer. Anticancer Res. 27: 2535-2539.
23. Peters JL, Sutton AJ, Jones DR, Abrams KR, et al. (2006). Comparison of two methods to detect publication bias in meta-analysis. JAMA 295: 676-680.
24. Ponder BA (2001). Cancer genetics. Nature 411: 336-341.
25. Renner W, Kotschan S, Hoffmann C, Obermayer-Pietsch B, et al. (2000). A common 936 C/T mutation in the gene for vascular endothelial growth factor is associated with vascular endothelial growth factor plasma levels. J. Vasc. Res. 37: 443-448.
26. Rothwell PM, Wilson M, Elwin CE, Norrving B, et al. (2010). Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials. Lancet 376: 1741-1750.
27. Saad RS, Kordunsky L, Liu YL, Denning KL, et al. (2006). Lymphatic microvessel density as prognostic marker in colorectal cancer. Mod. Pathol. 19: 1317-1323.
28. Schott RJ and Morrow LA (1993). Growth factors and angiogenesis. Cardiovasc. Res. 27: 1155-1161.
29. Taby R and Issa JP (2010). Cancer epigenetics. CA Cancer J. Clin. 60: 376-392.
30. Takahashi Y, Kitadai Y, Bucana CD, Cleary RK, et al. (1995). Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res. 55: 3964-3968.
31. Tanigawa N, Amaya H, Matsumura M, Lu C, et al. (1997). Tumor angiogenesis and mode of metastasis in patients with colorectal cancer. Cancer Res. 57: 1043-1046.
32. van Engeland M, Derks S, Smits KM, Meijer GA, et al. (2011). Colorectal cancer epigenetics: complex simplicity. J. Clin. Oncol. 29: 1382-1391.
33. Vandenbroucke JP, von EE, Altman DG, Gotzsche PC, et al. (2007). Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. Epidemiology 18: 805-835.
34. Venkatachalam R, Ligtenberg MJ, Hoogerbrugge N, de Bruijn DR, et al. (2010). The epigenetics of (hereditary) colorectal cancer. Cancer Genet. Cytogenet. 203: 1-6.
35. Viechtbauer W (2007). Confidence intervals for the amount of heterogeneity in meta-analysis. Stat. Med. 26: 37-52.
36. Vincenti V, Cassano C, Rocchi M and Persico G (1996). Assignment of the vascular endothelial growth factor gene to human chromosome 6p21.3. Circulation 93: 1493-1495.
37. Watson CJ, Webb NJ, Bottomley MJ and Brenchley PE (2000). Identification of polymorphisms within the vascular endothelial growth factor (VEGF) gene: correlation with variation in VEGF protein production. Cytokine 12: 1232-1235.
38. Weitz J, Koch M, Debus J, Höhler T, et al. (2005). Colorectal cancer. Lancet 365: 153-165.
39. Wu GY, Wang XM, Keese M, Hasenberg T, et al. (2006). Association between vascular endothelial growth factor gene 936 T/C polymorphism and colorectal cancer together with anastomotic leakage. Zhonghua Wai Ke Za Zhi 44: 1505-1507.
40. Zintzaras E and Ioannidis JP (2005). Heterogeneity testing in meta-analysis of genome searches. Genet. Epidemiol. 28: 123-137.