Participation of Gab1 and Gab2 in IL-22-mediated keratinocyte proliferation, migration, and differentiation

Molecular and Cellular Biochemistry

Volumn 369, Issue 1-2, 2012, Pages 255-266

  Zhu, Xiaofang ^a   Li, Zhongliang ^a   Pan, Wenyan ^a   Qin, Lu ^a   Zhu, Guoqiang ^a   Ke, Yuehai ^b   Wu, Jie ^c,d   Bo, Ping ^a   Meng, Songshu ^a  

^a YANGZHOU UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Cell differentiation; Extracellular receptor kinases (Erk); Grb2 associated binder; Interleukin 22; Keratinocyte; Src homology 2 containing protein tyrosine phosphatase (Shp2)

Indexed keywords

CELL PROTEIN; GRB2 ASSOCIATED BINDER 1; GRB2 ASSOCIATED BINDER 2; INTERLEUKIN 22; JANUS KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE TYK2; PROTEIN TYROSINE PHOSPHATASE SHP 2; SMALL INTERFERING RNA; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL LINE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; KERATINOCYTE; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; HUMANS; INTERLEUKINS; KERATINOCYTES; MUTATION; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; PSORIASIS; TYROSINE;

ADENOVIRIDAE;

EID: 84865635247     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1389-5     Document Type: Article

References (39)

1. W Ouyang 2010 Distinct roles of IL-22 in human psoriasis and inflammatory bowel disease Cytokine Growth Factor Rev 21 6 435 441 21106435 10.1016/j.cytogfr.2010.10.007 1:CAS:528:DC%2BC3cXhsFant7rK
2. HL Ma S Liang J Li L Napierata T Brown S Benoit M Senices D Gill K Dunussi-Joannopoulos M Collins C Nickerson-Nutter LA Fouser DA Young 2008 IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation J Clin Investig 118 2 597 607 18202747 1:CAS:528: DC%2BD1cXhsFOmsrg%3D (Pubitemid 351206549)
3. Y Zheng DM Danilenko P Valdez I Kasman J Eastham-Anderson J Wu W Ouyang 2007 Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis Nature 445 7128 648 651 17187052 10.1038/nature05505 1:CAS:528:DC%2BD2sXhtlOrtLk%3D (Pubitemid 46232884)
4. K Wolk E Witte E Wallace WD Docke S Kunz K Asadullah HD Volk W Sterry R Sabat 2006 IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis Eur J Immunol 36 5 1309 1323 16619290 10.1002/eji.200535503 1:CAS:528:DC%2BD28Xlt1ekurY%3D
5. K Boniface E Guignouard N Pedretti M Garcia A Delwail FX Bernard F Nau G Guillet G Dagregorio H Yssel JC Lecron F Morel 2007 A role for T cell-derived interleukin 22 in psoriatic skin inflammation Clin Exp Immunol 150 3 407 415 17900301 10.1111/j.1365-2249.2007.03511.x 1:CAS:528:DC%2BD1cXitVOktg%3D%3D (Pubitemid 350098734)
6. W Ouyang JK Kolls Y Zheng 2008 The biological functions of T helper 17 cell effector cytokines in inflammation Immunity 28 4 454 467 18400188 10.1016/j.immuni.2008.03.004 1:CAS:528:DC%2BD1cXkvV2itrY%3D (Pubitemid 351471762)
7. S Trifari CD Kaplan EH Tran NK Crellin H Spits 2009 Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)17, T(H)1 and T(H)2 cells Nat Immunol 10 8 864 871 19578368 10.1038/ni.1770 1:CAS:528:DC%2BD1MXotVClsbc%3D
8. T Duhen R Geiger D Jarrossay A Lanzavecchia F Sallusto 2009 Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells Nat Immunol 10 8 857 863 19578369 10.1038/ni.1767 1:CAS:528: DC%2BD1MXotVClsbw%3D
9. LA Zenewicz RA Flavell 2011 Recent advances in IL-22 biology Int Immunol 23 3 159 163 21393631 10.1093/intimm/dxr001 1:CAS:528:DC%2BC3MXjtFWgurY%3D
10. K Wolk HS Haugen W Xu E Witte K Waggie M Anderson E Vom Baur K Witte K Warszawska S Philipp C Johnson-Leger HD Volk W Sterry R Sabat 2009 IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not J Mol Med (Berl) 87 5 523 536 10.1007/s00109-009-0457-0 1:CAS:528:DC%2BD1MXkvV2jsbs%3D
11. R Sestito S Madonna C Scarponi F Cianfarani CM Failla A Cavani G Girolomoni C Albanesi 2011 STAT3-dependent effects of IL-22 in human keratinocytes are counterregulated by sirtuin 1 through a direct inhibition of STAT3 acetylation FASEB J 25 3 916 927 21098725 10.1096/fj.10-172288 1:CAS:528:DC%2BC3MXivF2lsb0%3D
12. H Gu BG Neel 2003 The "Gab" in signal transduction Trends Cell Biol 13 3 122 130 12628344 10.1016/S0962-8924(03)00002-3 1:CAS:528: DC%2BD3sXhs1WqsLg%3D (Pubitemid 36293784)
13. K Nishida T Hirano 2003 The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors Cancer Sci 94 12 1029 1033 14662016 10.1111/j.1349-7006.2003.tb01396.x 1:CAS:528:DC%2BD2cXhtlSrtbk%3D (Pubitemid 38035515)
14. A Kallin JB Demoulin K Nishida T Hirano L Ronnstrand CH Heldin 2004 Gab1 contributes to cytoskeletal reorganization and chemotaxis in response to platelet-derived growth factor J Biol Chem 279 17 17897 17904 14973141 10.1074/jbc.M312996200 1:CAS:528:DC%2BD2cXjt1Gmsrw%3D (Pubitemid 38560558)
15. M Laramee C Chabot M Cloutier R Stenne M Holgado-Madruga AJ Wong I Royal 2007 The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation J Biol Chem 282 11 7758 7769 17178724 10.1074/jbc.M611327200 1:CAS:528:DC%2BD2sXis1KgsL4%3D (Pubitemid 47093597)
16. T Cai K Nishida T Hirano PA Khavari 2002 Gab1 and SHP-2 promote Ras/MAPK regulation of epidermal growth and differentiation J Cell Biol 159 1 103 112 12370245 10.1083/jcb.200205017 1:CAS:528:DC%2BD38XnvFGkt70%3D (Pubitemid 35191522)
17. LS Lock CR Maroun MA Naujokas M Park 2002 Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis Mol Biol Cell 13 6 2132 2146 12058075 10.1091/mbc.02-02-0031. 1:CAS:528: DC%2BD38XltVWqt7o%3D (Pubitemid 34651497)
18. S Meng Z Chen T Munoz-Antonia J Wu 2005 Participation of both Gab1 and Gab2 in the activation of the ERK/MAPK pathway by epidermal growth factor Biochem J 391 Pt 1 143 151 15952937 1:CAS:528:DC%2BD2MXhtVehsLrI (Pubitemid 41445485)
19. H Kameda H Ishigami M Suzuki T Abe T Takeuchi 2006 Imatinib mesylate inhibits proliferation of rheumatoid synovial fibroblast-like cells and phosphorylation of Gab adapter proteins activated by platelet-derived growth factor Clin Exp Immunol 144 2 335 341 16634808 10.1111/j.1365-2249.2006.03067.x 1:CAS:528:DC%2BD28XltFajsbg%3D
20. C Caron K Spring M Laramee C Chabot M Cloutier H Gu I Royal 2009 Non-redundant roles of the Gab1 and Gab2 scaffolding adapters in VEGF-mediated signalling, migration, and survival of endothelial cells Cell Signal 21 6 943 953 19233262 10.1016/j.cellsig.2009.02.004 1:CAS:528:DC%2BD1MXjslKkurs%3D
21. Y Kuwano M Fujimoto R Watanabe N Ishiura H Nakashima M Komine TS Hamazaki K Tamaki H Okochi 2007 The involvement of Gab1 and PI 3-kinase in beta1 integrin signaling in keratinocytes Biochem Biophys Res Commun 361 1 224 229 17658473 10.1016/j.bbrc.2007.07.017 1:CAS:528:DC%2BD2sXotlWrur8%3D (Pubitemid 47102289)
22. S Meng Q Gui Q Xu K Lu X Jiao J Fan B Ge Y Ke S Zhang J Wu C Wang 2010 Association of Shp2 with phosphorylated IL-22R1 is required for interleukin-22-induced MAP kinase activation J Mol Cell Biol 2 4 223 230 20671117 10.1093/jmcb/mjq017 1:CAS:528:DC%2BC3cXhtFers7zM
23. JM Cunnick JF Dorsey T Munoz-Antonia L Mei J Wu 2000 Requirement of SHP2 binding to Grb2-associated binder-1 for mitogen-activated protein kinase activation in response to lysophosphatidic acid and epidermal growth factor J Biol Chem 275 18 13842 13848 10788507 10.1074/jbc.275.18.13842 1:CAS:528:DC%2BD3cXjtFyku7Y%3D (Pubitemid 30257458)
24. JM Cunnick L Mei CA Doupnik J Wu 2001 Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2 J Biol Chem 276 26 24380 24387 11323411 10.1074/jbc.M010275200 1:CAS:528:DC%2BD3MXltVWit7g%3D
25. JF Dorsey JM Cunnick SM Mane J Wu 2002 Regulation of the Erk2-Elk1 signaling pathway and megakaryocytic differentiation of Bcr-Abl(+) K562 leukemic cells by Gab2 Blood 99 4 1388 1397 11830491 10.1182/blood.V99.4.1388 1:CAS:528:DC%2BD38XhtlWqt78%3D (Pubitemid 34547096)
26. Gutowska-Owsiak D, Schaupp AL, Salimi M, Taylor S, Ogg GS (2011) Interleukin-22 downregulates filaggrin expression and affects expression of profilaggrin processing enzymes. Br J Dermatol 165(3):492-498
27. K Boniface FX Bernard M Garcia AL Gurney JC Lecron F Morel 2005 IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes J Immunol 174 6 3695 3702 15749908 1:CAS:528:DC%2BD2MXitVeht7Y%3D (Pubitemid 40354080)
28. D Lejeune L Dumoutier S Constantinescu W Kruijer JJ Schuringa JC Renauld 2002 Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line. Pathways that are shared with and distinct from IL-10 J Biol Chem 277 37 33676 33682 12087100 10.1074/jbc. M204204200 1:CAS:528:DC%2BD38Xnt1Srsr8%3D
29. SM Sa PA Valdez J Wu K Jung F Zhong L Hall I Kasman J Winer Z Modrusan DM Danilenko W Ouyang 2007 The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis J Immunol 178 4 2229 2240 17277128 1:CAS:528:DC%2BD2sXht1Cgu7Y%3D (Pubitemid 46233421)
30. K Wolk E Witte K Warszawska G Schulze-Tanzil K Witte S Philipp S Kunz WD Docke K Asadullah HD Volk W Sterry R Sabat 2009 The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis Eur J Immunol 39 12 3570 3581 19830738 10.1002/eji.200939687 1:CAS:528:DC%2BD1MXhsFaku77K
31. C Johansen K Kragballe M Westergaard J Henningsen K Kristiansen L Iversen 2005 The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin Br J Dermatol 152 1 37 42 15656798 10.1111/j.1365-2133. 2004.06304.x 1:CAS:528:DC%2BD2MXhvFCkurY%3D
32. S Wang H Uchi S Hayashida K Urabe Y Moroi M Furue 2009 Differential expression of phosphorylated extracellular signal-regulated kinase 1/2, phosphorylated p38 mitogen-activated protein kinase and nuclear factor-kappaB p105/p50 in chronic inflammatory skin diseases J Dermatol 36 10 534 540 19785707 10.1111/j.1346-8138.2009.00696.x 1:CAS:528:DC%2BD1MXhsVGnur7P
33. H Takahashi M Ibe S Nakamura A Ishida-Yamamoto Y Hashimoto H Iizuka 2002 Extracellular regulated kinase and c-Jun N-terminal kinase are activated in psoriatic involved epidermis J Dermatol Sci 30 2 94 99 12413764 10.1016/S0923-1811(02)00064-6 1:CAS:528:DC%2BD38XotF2iu74%3D (Pubitemid 36159019)
34. M Schmidt M Goebeler G Posern SM Feller CS Seitz EB Brocker UR Rapp S Ludwig 2000 Ras-independent activation of the Raf/MEK/ERK pathway upon calcium-induced differentiation of keratinocytes J Biol Chem 275 52 41011 41017 11018025 10.1074/jbc.M003716200 1:CAS:528:DC%2BD3MXjsVGkug%3D%3D (Pubitemid 32054928)
35. U Schaeper R Vogel J Chmielowiec J Huelsken M Rosario W Birchmeier 2007 Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo Proc Natl Acad Sci USA 104 39 15376 15381 17881575 10.1073/pnas.0702555104 1:CAS:528:DC%2BD2sXhtFWrsrfP (Pubitemid 47502925)
36. UM Halfter ZE Derbyshire RR Vaillancourt 2005 Interferon-gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytes Biochem J 388 Pt 1 17 28 15601262 1:CAS:528: DC%2BD2MXktVKnsLc%3D (Pubitemid 40732928)
37. K Ishihara T Hirano 2002 Molecular basis of the cell specificity of cytokine action Biochim Biophys Acta 1592 3 281 296 12421672 10.1016/S0167-4889(02)00321-X 1:CAS:528:DC%2BD38Xotl2nsrw%3D (Pubitemid 35284884)
38. FU Wohrle RJ Daly T Brummer 2009 Function, regulation and pathological roles of the Gab/DOS docking proteins Cell Commun Signal 7 22 19737390 10.1186/1478-811X-7-22
39. T Brummer D Schramek VM Hayes HL Bennett CE Caldon EA Musgrove RJ Daly 2006 Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein J Biol Chem 281 1 626 637 16253990 10.1074/jbc.M509567200 1:CAS:528:DC%2BD28Xht1ChtQ%3D%3D (Pubitemid 43671226)