Antimicrobial resistance in faecal Escherichia coli isolates from horses treated with antimicrobials: A longitudinal study in hospitalised and non-hospitalised horses

Veterinary Microbiology

Volumn 159, Issue 3-4, 2012, Pages 381-389

  Johns, Imogen ^a   Verheyen, Kristien ^a   Good, Liam ^a   Rycroft, Andrew ^a  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

Author keywords

Drug resistant; Equine; Escherichia coli; Extended spectrum beta lactamase

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMPICILLIN; CEPHALOSPORIN; CHLORAMPHENICOL; EXTENDED SPECTRUM BETA LACTAMASE; IMIPENEM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TETRACYCLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL THERAPY; ARTICLE; BACTERIAL SHEDDING; BACTERIUM ISOLATE; CONTROLLED STUDY; DISK DIFFUSION; ESCHERICHIA COLI; FECES ANALYSIS; FEMALE; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC CODE; HORSE; HOSPITALIZATION; LONGITUDINAL STUDY; MALE; MULTIDRUG RESISTANCE; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PREVALENCE;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL SHEDDING; BETA-LACTAMASES; DRUG RESISTANCE, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FECES; HORSE DISEASES; HORSES; LONGITUDINAL STUDIES;

EQUIDAE; ESCHERICHIA COLI;

EID: 84865634652     PISSN: 03781135     EISSN: 18732542     Source Type: Journal    
DOI: 10.1016/j.vetmic.2012.04.010     Document Type: Article

References (37)

1. Ahmed M.O., Clegg P.D., Williams N.J., Baptiste K.E., Bennett M. Antimicrobial resistance in equine faecal Escherichia coli isolates from North West England. Ann. Clin. Microbiol. Antimicrob. 2011, 9:12-18.
2. Angulo F.J., Nargund V.N., Chiller T.C. Evidence of an association between use of anti-microbial agents in food animals and anti-microbial resistance among bacteria isolated from humans and the human health consequences of such resistance. J. Vet. Med. 2004, 51:374-379.
3. Anon., 2007. OIE list of antimicrobials of veterinary importance. (accessed 25.07.11). http://www.web.oie.int/downld/Antimicrobials/OIE_list_antimicrobials.pdf.
4. Anon., 2009. Critically important antimicrobials for human medicine, 2nd revision. World Health Organisation (accessed 25.07.11). http://www.who.int/foodsafety/foodborne_disease/CIA_2nd_rev_2009.pdf.
5. Beard L.A. Multiple drug resistant bacteria in equine medicine: an emerging problem. Equine Vet. Educ. 2010, 22:287-289.
6. Boerlin P., Reid-Smith R.J. Antimicrobial resistance: its emergence and transmission. Animal Health Res. Rev. 2008, 9:115-126.
7. Bradford P.A. Extended-spectrum β-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistant threat. Clin. Microbiol. Rev. 2001, 14:933-951.
8. Bonnet R. Growing group of extended-spectrum-lactamases: the CTX-M enzymes. Antimicrob. Agents Chemother. 2004, 48:1-14.
9. British Society for Antimicrobial Chemotherapy (BSAC), 2009. BSAC Methods for Antimicrobial Sensitivity Testing (version 9.1) BSAC.org.uk.
10. Bryan J., Leonard N., Fanning S., Katz L., Duggan V. Antimicrobial resistance in commensal faecal Escherichia coli of hospitalized horses. Irish Vet. J. 2010, 63:373-379.
11. Cars O., Mosltad S., Melander A. Variation in antibiotic use in the European Union. Lancet 2001, 357:1851-1853.
12. Dallap Schaer B.L., Aceto H., Rankin S.C. Outbreak of Salmonellosis caused by Salmonella enteric serovar Newport MDR-AmpC in a large animal veterinary teaching hospital. J. Vet. Intern. Med. 2010, 24:1138-1146.
13. Damborg P., Marskar P., Baptiste K., Guardabassi L. Faecal shedding of CTX-M-producing Escherichia coli in horses receiving broad-spectrum antimicrobial prophylaxis after hospital admission. Vet. Microbiol. 2012, 154:298-304.
14. CTX-M-1 and qnr genes in Escherichia coli isolates from and equine clinic and a horseback riding centre. J. Antimicrob. Chemother. 2011, 66:757-764.
15. Dunowska M., Morley P.S., Traub-Dargatz J.L., Hyatt D.R., Dargatz D.A. Impact of hospitalization and antimicrobial drug administration on antimicrobial susceptibility patterns of commensal Escherichia coli isolated from the feces of horses. J. Am. Vet. Med. Assoc. 2006, 228:1909-1917.
16. Harris A.D., McGregor J.C., Johnson J.A., Strauss S.M., Moore A.C., Standiford H.C., Hebden J.N., Morris J.G. Risk factors for colonization with extended-spectrum beta-lactamase-producing bacteria and intensive care admission. Emerg. Infect. Dis. 2007, 13:1144-1149.
17. Lautenbach E., Tolomeo P., Mao X., Fishman N.O., Metlay J.P., Bilker W.B., Nachamkin I. Duration of outpatient fecal colonization due to Escherichia coli isolates with decreased susceptibility to fluoroquinolones: longitudinal study of patients recently discharged from the hospital. Antimicrob. Agents Chemother. 2006, 50:3939-3943.
18. Levesque C., Piche L., Larose C., Roy P.H. PCR mapping of integrons reveals several novel combinations of resistance genes. Antimicrob. Agents Chemother. 1995, 39:185-191.
19. Livermore D.M., Canton R., Gniadkowski M., Nordmann P., Rossolini G.M., Arlet G., Ayala J., Coque T.M. CTX-M: changing the face of ESBLs in Europe. J. Antimicrob. Chemother. 2007, 59:165-174.
20. Lowrance T.C., Longeragan G.H., Kunze D.J., Platt T.M., Ives S.E., Scott H.M., Norby B., Echeverry A., Brashears M.M. Changes in antimicrobial susceptibility in a population of Escherichia coli isolated from feedlot cattle administered ceftiofur crystalline-free acid. Am. J. Vet. Res. 2007, 68:501-507.
21. Maddox T.W., Williams N.J., Clegg P.D., O'Donnell A.J., Dawson S., Pinchbeck G. Longitudinal study of antimicrobial-resistant commensal Escherichia coli in faeces of horses in an equine hospital. Prev. Vet. Med. 2011, 100:134-145.
22. Maddox T.W., Clegg P.D., Diggle P.J., Wedley A.L., Dawson S., Pinchbeck G.L., Williams N.J. Cross-sectional study of antimicrobial-resistant bacteria in horses, Part 1: Prevalence of anti-microbial resistant Escherichia coli and methicillin-resistant Staphylococcus aureus. Equine Vet. J. 2011, (Epub ahead of print). 10.1111/j.2042-3306.2011.00441.x.
23. Maddox T.W., Pinchbeck G.L., Clegg P.D., Wedley A.L., Dawson S., Williams N.J. Cross sectional study of antimicrobial-resistant bacteria in horses, Part 2: Risk factors for faecal carriage of antimicrobial-resistant Escherichia coli in horses. Equine Vet. J. 2011, (Epub ahead of print). 10.1111/j.2042-3306.2011.00440.x.
24. McClure S., Sibert G., Hallberg J., Bade D. Efficacy of a 2-dose regimen of a sustained release ceftiofur suspension in horses with Streptococcus equi subsp zooepidemicus bronchopneumonia. J. Vet. Pharmacol. Ther. 2011, 34:442-447.
25. McDermott P.F., Cullen P., Hubert S.H., McDermott S.D., Bartholomew M., Simjee S., Wagner D.D. Changes in antimicrobial susceptibility of native Enterococcus faecium in chickens fed virginiamycin. Appl. Environ. Microbiol. 2005, 71:4986-4991.
26. Mølgak K. Spread of resistant bacteria and resistance genes from animals to humans - the public health consequences. J. Vet. Med. B: Infect. Dis. Vet. Public Health 2004, 51:364-369.
27. National Committee for Clinical Laboratory Standards Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated from Animals; Informational Supplement 2004, M31-S1, NCCLS, Wayne, PA, USA.
28. Ofner-Agostini M., Simor A., Mulvey M., McGreer A., Hirji Z., McCracken M., Gravel D., Boyd D., Bryce E. Risk factors for and outcomes associated with clinical isolates for Escherichia coli and Klebsiella species resistant to extended-spectrum cephalosporins among patients admitted to Canadian hospitals. Can. J. Infect. Dis. Med. Microbiol. 2009, 20:43-48.
29. Pitout J.D., Church D.L., Gregson D.B., Chow B.L., McCracken M., Mulvey M.R., Laupland K.B. Molecular epidemiology of CTX-M-producing Escherichia coli in the Calgary Health Region: emergence of CTX-M-producing isolates. Antimicrob. Agents Chemother. 2007, 51:1281-1286.
30. Raum E., Lietzau S., von Baum H., Marre R., Brenner H. Changes in Escherichia coli resistance patterns during and after antibiotic therapy: longitudinal study among outpatients in Germany. Clin. Microbiol. Infect. 2007, 14:41-48.
31. Schwaber M.J., Navon-Venezia S., Schwartz D., Carmeli Y. High levels of antimicrobial coresistance among extended-spectrum-β-lactamase-producing Enterobacteriaceae. Antimicrob. Agents Chemother. 2005, 49:2137-2139.
32. Thomas E., Thomas V., Wilhelm C. Antibacterial activity of cefquinome against equine bacterial pathogens. Vet. Microbiol. 2006, 115:140-147.
33. Tofteland S., Haldorsen B., Dahl K.H., Simonsen G.S., Steinbakk M., Walsh T.R., Sundsfjord A. Effects of phenotype and genotype on methods for detection of extended-spectrum-β-lactamase producing clinical isolates of Escherichia coli and Klebsiella pneumoniae in Norway. J. Clin. Microbiol. 2007, 45:199-205. Norwegian ESBL Study Group.
34. Turnidge J. Antibiotic use in animals - prejudices, perceptions and realities. J. Antimicrob. Chemother. 2004, 53:26-27.
35. Vo A.T.T., van Duijkeren E., Fluit A.C., Gaastra W. Characteristics of extended-spectrum cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae isolates from horses. Vet. Microbiol. 2007, 124:248-255.
36. Wasyl D., Hasman H., Cavaco L.M., Aarestrup F.M. Prevalence and characterization of cephalosporin resistance in nonpathogenic Escherichia coli from food-producing animals slaughtered in Poland. Microbiol. Drug Resist. 2011, (Epub ahead of print). 10.1089/mdr.2011.0033.
37. Woodford N., Ward M.E., Kaufmann M.E.D., Turton J., Fagan E.J., James D., Johnson A.P., Pike R., Warner M., Cheasty T., Pearson A., Harry S., Leach J.B., Loughrey A., Lowes J.A., Warren R.E., Livermore D.M. Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum beta-lactamases in the UK. J. Antimicrob. Chemother. 2004, 54:735-743.