Mass transfer characteristics of multiple-impeller fermenters for their design and scale-up

Biochemical Engineering Journal

Volumn 69, Issue , 2012, Pages 17-27

  Moucha, T ^a   Rejl, F J ^a   Kordac M ^a   Labik L ^a  

^a INSTITUTE OF CHEMICAL TECHNOLOGY   (Czech Republic)

Author keywords

Fermenter; Mass transfer; Mass transfer correlations; Mixing; Multiple impeller; Scale up; Volumetric mass transfer coefficient

Indexed keywords

BIOCHEMICAL INDUSTRIES; DIFFERENT SCALE; ENGINEERING PARAMETERS; EQUIPMENT PARAMETERS; EXPERIMENTAL TECHNIQUES; GAS RESIDENCE; GAS-LIQUID CONTACTORS; INDUSTRIAL SCALE; INITIAL COSTS; MASS TRANSFER CORRELATION; MULTIPLE-IMPELLER; OPERATING CONDITION; PER UNIT VOLUME; POWER INPUT; PROCESS PARAMETERS; PURE WATER; RATIONAL DESIGN; SCALE-UP; SULPHATE SOLUTIONS; TRANSFER CHARACTERISTICS; VOLUMETRIC MASS TRANSFER COEFFICIENT;

CHEMICAL ENGINEERING; DESIGN; IMPELLERS; LIQUID FILMS; MASS TRANSFER; MIXING; OPERATING COSTS; SODIUM; VOLUMETRIC ANALYSIS;

FERMENTERS;

SODIUM SULFATE;

ARTICLE; BIOREACTOR; CHEMICAL ENGINEERING; CHLORINATION; EQUIPMENT; GAS; HYDROGENATION; LIQUID; PRIORITY JOURNAL; SCALE UP;

EID: 84865633729     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2012.08.007     Document Type: Article

References (40)

1. Gogate P.R., Pandit A.B. Survey of measurement techniques for gas-liquid mass transfer coefficient in bioreactors. Biochem. Eng. J. 1999, 4:7-15.
2. Kraakman N.J., Rocha-Rios J., van Loosdrecht M.C.M. Review of mass transfer aspects for biological gas treatment. Appl. Microbiol. Biotechnol. 2011, 91:873-886.
3. Takahashi K., Nienow A.W. Bubble sizes and coaelescence rates in an aerated vessel agitated by a rushton turbine. J. Chem. Eng. Jpn. 1993, 25:536-542.
4. Timson W.J., Dunn Mechanism of gas absorption from bubbles under shear. Ind. Eng. Chem. 1960, 52:799-802.
5. Okawa T., Yoneda K., Zhou S. New interfacial drag force model including effect of bubble wake. J. Nucl. Sci. Technol. 1999, 36:1030-1040.
6. Del Castillo L.A., Ohnishi S., Horn R.G. Inhibition of bubble coalescence: effects of salt concentration and speed of approach. J. Colloid Interface Sci. 2011, 356:316-324.
7. Talaia M.A.R. Terminal velocity of a bubble rise in a liquid column. World Acad. Sci. Eng. Technol. 2007, 28:264-268.
8. Prince M.J., Blanch H.W. Bubble coalescence and break-up in air-sparged bubble columns. AIChE J. 1990, 36:1485-1499.
9. Kawase Y., Moo-Young M. Volumetric mass transfer coefficient in aerated stirred tank reactors with Newtonian and non-Newtonian media. Chem. Eng. Res. Des. 1988, 66:284-288.
10. Ranganathan P., Sivaraman S. Investigations on hydrodynamics and mass transfer in gas-liquid stirred reactor using computational fluid dynamics. Chem. Eng. Sci. 2011, 66:3108-3124.
11. Alves S.S., Maia C.I., Vasconcelos J.M.T. Gas-liquid mass transfer coefficient in stirred tanks interpreted through bubble contamination kinetics. Chem. Eng. Process. 2004, 43:823-830.
12. Martin M., Montes F.J., Galan M.A. Physical explanation of the empirical coefficients of gas-liquid mass transfer equations. Chem. Eng. Sci. 2009, 64:410-425.
13. van't Riet K. Review of measuring methods and results in nonviscous gas-liquid mass transfer in stirred vessels. IEC Proc. Des. Dev. 1979, 18:357-364.
14. Herbst H., Schumpe A., Deckwer W.D. Xanthan production in stirred tank fermenters: oxygen transfer and scale-up. Chem. Eng. Technol. 1992, 15:425-434.
15. Nocentini M., Fajner D., Pasquali G., Magelli F. Gas-liquid mass transfer and hold-up in vessels stirred with multiple Rushton turbines: water and water-glycerol solutions. Ind. Eng. Chem. Res. 1993, 32:19-26.
16. Robinson C.W., Wilke C.R. Oxygen absorption in stirred tanks: a correlation for ionic strength effects. Biotechnol. Bioeng. 1973, 15:755-782.
17. Linek V., Vacek V., BeneŠ P. A critical review and experimental verification of the correct use of the dynamic method for the determination of oxygen transfer in aerated agitated vessels to water, electrolyte solutions and viscous liquids. Chem. Eng. J. 1987, 34:11-34.
18. Puthli M.S., Rathod V.K., Pandit A.B. Gas-liquid mass transfer studies with triple impeller system on a laboratory scale bioreactor. Biochem. Eng. J. 2005, 23:25-30.
19. Pedersen A.G., Andersen H., Nielsen J., Villadsen J. A novel experimental technique based on 85Kr for quantification of gas-liquid mass transfer in bioreactors. Chem. Eng. Sci. 1994, 49:803-810.
20. La measurement in large-scale fermentors. Biotechnol. Bioeng. 1987, 29:982-993.
21. Linek V., BeneŠ P., Holeček O. Correlation for volumetric mass transfer coefficient in mechanically agitated aerated vessel for oxygen absorption in aqueous electrolyte solutions. Biotechnol. Bioeng. 1988, 32:482-490.
22. Poizat T., Jallut C., Accary A., Lieto J. A novel experimental technique for measurement of mass transfer between liquids and gas bubbles in agitated vessels: application to highly viscous liquids. Chem. Eng. J. 1992, 48:41-48.
23. La in bioreactors. J. Biotechnol. 2005, 120:430-438.
24. Pinelli D. A phenomenological model for the gas phase flowing high-aspect-ratio stirred vessels: the role of small bubbles in non-coalescent and moderately viscous liquids. Chem. Eng. Sci. 2005, 60:2239-2252.
25. Havelka P., Linek V., Sinkule J., Zahradník J., Fialová M. Hydrodynamic and mass transfer characteristics of ejector loop reactors. Chem. Eng. Sci. 2000, 55:535-549.
26. Midoux N., Laurent A., Charpentier J.C. Limits of the chemical method for the determination of physical mass transfer parameters in mechanically agitated gas-liquid reactors. AIChE J. 1980, 26:157-161.
27. Linek V., Moucha T., Sinkule J. Gas-liquid mass transfer in vessels stirred with multiple impellers-Part I: Gas-liquid mass transfer characteristics in individual stages. Chem. Eng. Sci. 1996, 51:3203-3212.
28. La in gas-liquid dispersions. Chem. Eng. Commun. 1998, 168:97-110.
29. La measurement. Chem. Eng. Sci. 1993, 48:1593-1599.
30. La determination in stirred Newtonian and non-Newtonian fluids, culture media and fermentation broths. Biochem. Eng. J. 2004, 18:185-192.
31. La measurement in aerated bioreactors. Biochem. Eng. J. 2010, 49:165-172.
32. Miller D.N. Scale-up of agitated vessels gas-liquid mass transfer. AIChE J. 1974, 20:445-453.
33. Moucha T., Linek V., Erokhin K., Rejl F.J., Fujasová M. Improved power and mass transfer correlations for design and scale-up of multiple-impeller gas-liquid contactors. Chem. Eng. Sci. 2009, 64:598-604.
34. La by dynamic method. Trans. IChemE 1991, 69A:308-312.
35. Garcia-Ochoa F., Gomez E. Mass transfer coefficient in stirred tank reactors for xanthan gum solutions. Biochem. Eng. J. 1998, 1:1-10.
36. Jordan U., Schumpe A. The gas density effect on mass transfer in bubble columns with organic liquids. Chem. Eng. Sci. 2001, 56:6267-6272.
37. Moucha T., Linek V., Prokopová E. Gas hold-up, mixing time and gas-liquid volumetric mass transfer coefficient of various multiple-impeller configurations: rushton turbine, pitched blade and techmix impeller and their combinations. Chem. Eng. Sci. 2003, 58:1839-1846.
38. La values measured by the dynamic pressure method in individual stages of the vessel. Chem. Eng. Sci. 2007, 62:1650-1669.
39. La values in individual stages of multiple-impeller vessel. Collect. Czech. Chem. Commun. 1998, 63:2103-2113.
40. Batchelor G.K. The Theory of Homogeneous Turbulence 1953, Cambridge University Press, Cambridge.