Simplified dynamic pressure method for kL a measurement in aerated bioreactors

Biochemical Engineering Journal

Volumn 49, Issue 2, 2010, Pages 165-172

  Scargiali, F ^a   Busciglio, A ^a   Grisafi, F ^a   Brucato, A ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

Dynamic modelling; Gas liquid mass transfer; kL a; Multiphase bioreactors; Oxygen transfer; Stirred vessels

Indexed keywords

CONVENTIONAL POWER; DATA TREATMENT; DRIVING FORCES; DYNAMIC MODELLING; DYNAMIC PRESSURES; EXPERIMENTAL DATA; GAS-LIQUID MASS TRANSFER; GAS-LIQUID SYSTEMS; LIQUID PHASE; LITERATURE DATA; MASS TRANSFER COEFFICIENT; MODEL PREDICTION; OXYGEN CONCENTRATIONS; OXYGEN TRANSFER; PRESSURE CHANGE; PURE OXYGEN; STIRRED TANK REACTORS; STIRRED VESSELS; STRAIGHT LINES; SUDDEN CHANGE; TOTAL PRESSURE;

BIOREACTORS; DYNAMIC RESPONSE; GAS ABSORPTION; MASS TRANSFER; MATHEMATICAL MODELS; OXYGEN;

LIQUIDS;

ARTICLE; BIOREACTOR; LIQUID; MATHEMATICAL MODEL; OXYGEN CONCENTRATION; PRESSURE; PRIORITY JOURNAL;

EID: 77249173225     PISSN: 1369703X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bej.2009.12.008     Document Type: Article

References (21)

1. Garcia-Ochoa F., and Gomez E. Bioreactor scale-up and oxygen transfer rate in microbial processes: an overview. Biotechnol. Adv. 27 (2009) 153-176
2. Van't Riet K. Reviewing of measuring method and results in nonviscous gas-liquid mass transfer in stirred vessels. Ind. Eng. Chem. Proc. Des. Dev. 18 (1979) 357-364
3. Chapman C., Gibilaro L., and Nienow A. A dynamic response technique for the estimation of gas-liquid mass transfer coefficients in a stirred vessel. Chem. Eng. Sci. 37 6 (1982) 891-896
4. Linek V., Vacek P., and Benes P. A critical review and experimental verification of the correct use of the dynamic method for the determination of oxygen tranfer in aerated agitated vessels to water, electrolyte solutions and viscous liquids. Chem. Eng. J. 34 (1987) 11-34
5. Gogate P., and Pandit A. Survey of measurement techniques for gas liquid mass transfer coefficient in bioreactors. Biochem. Eng. J. 4 (1999) 7-15
6. Pinelli D. The role of small bubbles in gas-liquid mass transfer in stirred vessels and assessment of a two-fraction model for noncoalescent or moderately viscous liquids. Chem. Eng. Sci. 62 (2007) 3767-3776
7. Cabaret F., Fradette L., and Tanguy P. Gas-liquid mass transfer in unbaffled dual impeller mixer. Chem. Eng. Sci. 63 (2008) 1636-1647
8. l a measurement and models comparison. Trans. IChemE 68 A (1990) 287-294
9. l a measurement. Trans. IChemE 75 A (1997) 467-472
10. l a values determined by steady state and dynamic methods in stirred tanks. Chem. Eng. J. 25 (1982) 77-88
11. Stenberg O., and Andersson B. Gas liquid mass transfer in agitated vessels. I. Evaluation of the gas-liquid mass transfer coefficient from transient-response measurements. Chem. Eng. Sci. 43 3 (1988) 724-729
12. Scargiali F., Russo R., Grisafi F., and Brucato A. Mass transfer and hydrodynamic characteristics of a high aspect ratio self-ingesting reactor for gas-liquid operations. Chem. Eng. Sci. 62 (2007) 1376-1387
13. l a measurement in large scale bioreactors. Biotechnol. Bioeng. 33 (1989) 1406-1412
14. l a measurement. Chem. Eng. Sci. 48 9 (1993) 1593-1599
15. l a in multiple impeller vessels with significant dispersion of in both phases. Trans. I. Chem. Eng. 73A (1995) 286-290
16. l a values measured by the dynamic pressure method in individual stages of the vessel. Chem. Eng. Sci. 62 (2007) 1650-1669
17. l a determination in stirred newtonian and non-Newtonian fluids, culture media and fermentation broths. Biochem. Eng. J. 18 (2004) 185-192
18. Conway K., Kyle A., and Rielly C. Gas-liquid-solid operation of a vortex ingesting stirred tank reactor. Trans. IChemE 80(A) (2002) 839-845
19. Perry R., and Green D. Perry's Chemical Engineers' Handbook. 8th edition (2008), McGraw-Hill Int.
20. F. Scargiali, Gas-liquid dispersions in mechanically agitated contactors, PhD thesis, Universitá degli Studi di Palermo (2007).
21. Grisafi F., Brucato A., and Rizzuti L. Solid-liquid mass transfer coefficients in gas-solid-liquid agitated vessels. Can. J. Chem. Eng. 76 (1998) 446-455