Role of wild type p53 and double suicide genes in interventional therapy of liver cancer in rabbits;Papel do p53 selvagem e do duplo genes suicidas na terapia intervencionista do câncer de fígado em coelhos

Acta Cirurgica Brasileira

Volumn 27, Issue 8, 2012, Pages 522-528

  Niu, Hong Xin ^a   Du, Tong ^a   Xu, Zhong Fa ^a   Zhang, Xi Kun ^a   Wang, Ruo Gu ^a  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

Author keywords

Gene therapy; Genes; Liver neoplasms; P53; Rabbits

Indexed keywords

FLUOROURACIL; GANCICLOVIR; IODINATED POPPYSEED OIL; PROTEIN P53; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL EMBOLISM; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER MODEL; CANCER SIZE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; ECHOGRAPHY; FACTORIAL ANALYSIS; GENE THERAPY; LIVER CANCER; NONHUMAN; RABBIT; WILD TYPE;

ANIMALS; ANTINEOPLASTIC AGENTS; COMBINED MODALITY THERAPY; DISEASE MODELS, ANIMAL; EMBOLIZATION, THERAPEUTIC; ETHIODIZED OIL; FEASIBILITY STUDIES; GENES, P53; GENES, TRANSGENIC, SUICIDE; GENETIC THERAPY; LIVER NEOPLASMS; RABBITS; RANDOM ALLOCATION; TIME FACTORS; TREATMENT OUTCOME;

EID: 84865626373     PISSN: 01028650     EISSN: 16782674     Source Type: Journal    
DOI: 10.1590/S0102-86502012000800002     Document Type: Article

References (16)

1. Liu T, Ye L, He Y, Chen X, Peng J, Zhang X, Yi H, Peng F, Leng A. Combination gene therapy using VEGF-shRNA and fusion suicide gene yCDglyTK inhibits gastric carcinoma growth. Exp Mol Pathol. 2011;91(3):745-52.
2. Lee SW, Lee YL, Lee YJ, Park SY, Kim IS, Choi TH, Ha JH, Ahn BC, Lee J. Enhanced antitumor effects by combination gene therapy using MDR1 gene shRNA and HSV1-tk in a xenograft mouse model. Cancer Lett. 2010;291(1):83-9.
3. Niu HX, He QS, Tan W, Gao J. Inhibitory effects of WTp53 gene in combination with TK/GCV and CD/5-FC systems on liver metastasis of colon carcinoma in nude mice. Chin J Hepatob Surg. 2007;13(10):690-3.
4. Niu HX, He QS, Wei D. Investigation of inhibition of liver metastasis of colon carcinoma on the nude mice models with the system of TKGCV and CD/5-Fc. Chin J Curr Adv Gen Surg. 2007;10(3):203-7
5. 2 carcinoma in rabbit live as a model. Chin J Clin Oncol. 2006;2:134-7.
6. Zhong L, Yu ZJ, Mu GF, Quan XY. The improvement of catheterization technique in rabbit VX2 hepatoma model and its manifestation in DSA. J Pract Med. 2007;23(12):1803-5.
7. Xu WG, Tan GS, Peng XB. Comparison of transfemoral hepatic artery catheterization and direct hepatic artery catheterization via laparotomy in rabbits. World Chin J Digestol. 2009;17(25):2612-5.
8. Zhou CK, Liang HM, Li X, Liu X. Establishment of rabbit model bearing VX2 liver tumor experimentation and discussion of the selective hepatic arterial catheterization. J Intervent Radiol. 2006;15(2):101-4.
9. Staib F, Hussain SP, Hofseth LJ, Wang XW, Harris CC. TP53 and liver carcinogenesis. Hum Mutat. 2003;21(3):201-16.
10. Hickman ES, Helin K. The p53 tumour suppressor protein. Biotechnol Genet Eng Rev. 2000;17:179-211.
11. Kojima Y, Honda K, Hamada H, Kobayashi N. Oncolytic gene therapy combined with double suicide genes for human bile duct cancer in nude mouse models. J Surg Res. 2009;157(1):e63-70.
12. Luo XR, Li JS, Niu Y, Miao L. Targeted killing effects of double CD and TK suicide genes controlled by survivin promoter on gastric cancer cell. Mol Biol Rep. 201;38(2):1201-7.
13. Kesmodel SB, Spitz FR. Gene therapy for cancer and metastatic disease. Expert Rev Mol Med. 2003;5(17):1-18.
14. Yu M, Chen W, Zhang J. p53 gene therapy for pulmonary metastasis tumor from hepatocellular carcinoma. Anticancer Drugs. 2010;21(9):882-4.
15. Lemarié F, Croft DR, Tate RJ, Ryan KM, Dufès C. Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system. Biomaterials. 2012;33(9):2701-9.
16. Zhu GY, Lu Q, Teng GJ. Experimental research on treating hepatic carcinoma by arterial injection of liposome mediated p53 genes. J Intervent Radiol. 2007;16(2):109-14.