메뉴 건너뛰기




Volumn 5, Issue 17, 2003, Pages

Gene therapy for cancer and metastatic disease

Author keywords

anti angiogenic agents; cancer; gene therapy; gene therapy vectors; immunopotentiation; metastatic disease; mutation compensation; suicide gene therapy; viral oncolysis

Indexed keywords

ANIMAL; GENE THERAPY; GENE VECTOR; HUMAN; METASTASIS; MULTIMODALITY CANCER THERAPY; NEOPLASM; REVIEW;

EID: 22544482819     PISSN: 14623994     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1462399403006380     Document Type: Review
Times cited : (16)

References (127)
  • 2
    • 0023145547 scopus 로고
    • The molecular genetics of cancer
    • Bishop, J.M. (1987) The molecular genetics of cancer. Science 235, 305-311, PubMed: 87094203 (Pubitemid 17232555)
    • (1987) Science , vol.235 , Issue.4786 , pp. 305-311
    • Bishop, J.M.1
  • 3
    • 0030240944 scopus 로고    scopus 로고
    • How cancer arises
    • PubMed: 96327166
    • Weinberg, R.A. (1996) How cancer arises. Sci Am 275, 62-70, PubMed: 96327166
    • (1996) Sci Am , vol.275 , pp. 62-70
    • Weinberg, R.A.1
  • 4
    • 0034913116 scopus 로고    scopus 로고
    • Nonviral vectors in the new millennium: Delivery barriers in gene transfer
    • DOI 10.1089/104303401750195836
    • Nishikawa, M. and Huang, L. (2001) Nonviral vectors in the new millennium: delivery barriers in gene transfer. Hum Gene Ther 12, 861-870, PubMed: 21280921 (Pubitemid 32681851)
    • (2001) Human Gene Therapy , vol.12 , Issue.8 , pp. 861-870
    • Nishikawa, M.1    Huang, L.2
  • 5
    • 0033972869 scopus 로고    scopus 로고
    • Nonviral gene therapy: Promises and challenges
    • Li, S. and Huang, L. (2000) Nonviral gene therapy: promises and challenges. Gene Ther 7, 31-34, PubMed: 20146294 (Pubitemid 30077146)
    • (2000) Gene Therapy , vol.7 , Issue.1 , pp. 31-34
    • Li, S.1    Huang, L.2
  • 6
    • 0028245537 scopus 로고
    • Cationic liposomes for direct gene transfer in therapy of cancer and other diseases
    • discussion 34-25, PubMed: 94295994
    • Farhood, H. et al. (1994) Cationic liposomes for direct gene transfer in therapy of cancer and other diseases. Ann N Y Acad Sci 716, 23-34; discussion 34-25, PubMed: 94295994
    • (1994) Ann N y Acad Sci , vol.716 , pp. 23-34
    • Farhood, H.1
  • 7
    • 0031884632 scopus 로고    scopus 로고
    • Viral vectors for gene therapy
    • DOI 10.1016/S0167-7799(97)01137-2
    • Robbins, P.D., Tahara, H. and Ghivizzani, S.C. (1998) Viral vectors for gene therapy. Trends Biotechnol 16, 35-40, PubMed: 98131005 (Pubitemid 28064816)
    • (1998) Trends in Biotechnology , vol.16 , Issue.1 , pp. 35-40
    • Robbins, P.D.1    Tahara, H.2    Ghivizzani, S.C.3
  • 8
    • 0035135747 scopus 로고    scopus 로고
    • Viral vectors for gene therapy: The art of turning infectious agents into vehicles of therapeutics
    • DOI 10.1038/83324
    • Kay, M.A., Glorioso, J.C. and Naldini, L. (2001) Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. Nat Med 7, 33-40, PubMed: 21065270 (Pubitemid 32095639)
    • (2001) Nature Medicine , vol.7 , Issue.1 , pp. 33-40
    • Kay, M.A.1    Glorioso, J.C.2    Naldini, L.3
  • 9
    • 0025231388 scopus 로고
    • Direct gene transfer into mouse muscle in vivo
    • PubMed: 90208305
    • Wolff, J.A. et al. (1990) Direct gene transfer into mouse muscle in vivo. Science 247, 1465-1468, PubMed: 90208305
    • (1990) Science , vol.247 , pp. 1465-1468
    • Wolff, J.A.1
  • 13
    • 0027031422 scopus 로고
    • Gene transfer in vivo with DNA-liposome complexes: Lack of autoimmunity and gonadal localization
    • PubMed: 93129664
    • Nabel, E.G. et al. (1992) Gene transfer in vivo with DNA-liposome complexes: lack of autoimmunity and gonadal localization. Hum Gene Ther 3, 649-656, PubMed: 93129664
    • (1992) Hum Gene Ther , vol.3 , pp. 649-656
    • Nabel, E.G.1
  • 14
    • 0034927057 scopus 로고    scopus 로고
    • Replication-selective virotherapy for cancer: Biological principles, risk management and future directions
    • DOI 10.1038/89901
    • Kirn, D., Martuza, R.L. and Zwiebel, J. (2001) Replication-selective virotherapy for cancer: Biological principles, risk management and future directions. Nat Med 7, 781-787, PubMed: 21326518 (Pubitemid 32691631)
    • (2001) Nature Medicine , vol.7 , Issue.7 , pp. 781-787
    • Kirn, D.1    Martuza, R.L.2    Zwiebel, J.3
  • 15
    • 0037020112 scopus 로고    scopus 로고
    • Clinical research. Gene therapy a suspect in leukemia-like disease
    • PubMed: 22251323
    • Marshall, E. (2002) Clinical research. Gene therapy a suspect in leukemia-like disease. Science 298, 34-35, PubMed: 22251323
    • (2002) Science , vol.298 , pp. 34-35
    • Marshall, E.1
  • 16
    • 0029023868 scopus 로고
    • Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
    • PubMed: 96071601
    • Mineta, T. et al. (1995) Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat Med 1, 938-943, PubMed: 96071601
    • (1995) Nat Med , vol.1 , pp. 938-943
    • Mineta, T.1
  • 17
    • 0028559601 scopus 로고
    • Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase
    • PubMed: 95064020
    • During, M.J. et al. (1994) Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase. Science 266, 1399-1403, PubMed: 95064020
    • (1994) Science , vol.266 , pp. 1399-1403
    • During, M.J.1
  • 18
    • 0035819551 scopus 로고    scopus 로고
    • Gene delivery and gene therapy with herpes simplex virus-based vectors
    • DOI 10.1016/S0378-1119(01)00322-5, PII S0378111901003225
    • Latchman, D.S. (2001) Gene delivery and gene therapy with herpes simplex virus-based vectors. Gene 264, 1-9, PubMed: 21142387 (Pubitemid 32195481)
    • (2001) Gene , vol.264 , Issue.1 , pp. 1-9
    • Latchman, D.S.1
  • 19
    • 0031422449 scopus 로고    scopus 로고
    • The use of herpes simplex virus-based vectors for gene delivery to the nervous system
    • DOI 10.1016/S1357-4310(97)01106-4, PII S1357431097011064
    • Lachmann, R.H. and Efstathiou, S. (1997) The use of herpes simplex virus-based vectors for gene delivery to the nervous system. Mol Med Today 3, 404-411, PubMed: 97448281 (Pubitemid 28127960)
    • (1997) Molecular Medicine Today , vol.3 , Issue.9 , pp. 404-411
    • Lachmann, R.H.1    Efstathiou, S.2
  • 20
    • 0033759405 scopus 로고    scopus 로고
    • Production of first generation adenovirus vectors: A review
    • PubMed: 20534462
    • Danthinne, X. and Imperiale, M.J. (2000) Production of first generation adenovirus vectors: a review. Gene Ther 7, 1707-1714, PubMed: 20534462
    • (2000) Gene Ther , vol.7 , pp. 1707-1714
    • Danthinne, X.1    Imperiale, M.J.2
  • 21
    • 0029028989 scopus 로고
    • Clearance of adenovirus-infected hepatocytes by MHC class I-restricted CD4+ CTLs in vivo
    • PubMed: 95378679
    • Yang, Y. and Wilson, J.M. (1995) Clearance of adenovirus-infected hepatocytes by MHC class I-restricted CD4+ CTLs in vivo. J Immunol 155, 2564-2570, PubMed: 95378679
    • (1995) J Immunol , vol.155 , pp. 2564-2570
    • Yang, Y.1    Wilson, J.M.2
  • 23
    • 0033761804 scopus 로고    scopus 로고
    • Adeno-associated virus vectors for gene therapy: More pros than cons?
    • PubMed: 20528777
    • Monahan, P.E. and Samulski, R.J. (2000) Adeno-associated virus vectors for gene therapy: more pros than cons? Mol Med Today 6, 433-440, PubMed: 20528777
    • (2000) Mol Med Today , vol.6 , pp. 433-440
    • Monahan, P.E.1    Samulski, R.J.2
  • 24
    • 0031608678 scopus 로고    scopus 로고
    • P53 tumor suppressor gene therapy for cancer
    • Nielsen, L.L. and Maneval, D.C. (1998) P53 tumor suppressor gene therapy for cancer. Cancer Gene Ther 5, 52-63, PubMed: 98135834 (Pubitemid 128639991)
    • (1998) Cancer Gene Therapy , vol.5 , Issue.1 , pp. 52-63
    • Nielsen, L.L.1    Maneval, D.C.2
  • 25
    • 0025894713 scopus 로고
    • P53 mutations in human cancers
    • PubMed: 91289156
    • Hollstein, M. et al. (1991) p53 mutations in human cancers. Science 253, 49-53, PubMed: 91289156
    • (1991) Science , vol.253 , pp. 49-53
    • Hollstein, M.1
  • 26
    • 0034475167 scopus 로고    scopus 로고
    • Pre-clinical studies with tumor suppressor genes
    • Seth, P. (2000) Pre-clinical studies with tumor suppressor genes. Adv Exp Med Biol 465, 183-192, PubMed: 20270923 (Pubitemid 32193334)
    • (2000) Advances in Experimental Medicine and Biology , vol.465 , pp. 183-192
    • Seth, P.1
  • 29
    • 0033895499 scopus 로고    scopus 로고
    • Suppression of primary tumor growth and the progression to metastasis with p53 adenovirus in human prostate cancer
    • Eastham, J.A. et al. (2000) Suppression of primary tumor growth and the progression to metastasis with p53 adenovirus in human prostate cancer. J Urol 164, 814-819, PubMed: 20411379 (Pubitemid 30637639)
    • (2000) Journal of Urology , vol.164 , Issue.3 , pp. 814-819
    • Eastham, J.A.1    Grafton, W.2    Martin, C.M.3    Williams, B.J.4
  • 34
    • 0029960147 scopus 로고    scopus 로고
    • Adenoviral-mediated p53 tumor suppressor gene therapy of human ovarian carcinoma
    • Mujoo, K. et al. (1996) Adenoviral-mediated p53 tumor suppressor gene therapy of human ovarian carcinoma. Oncogene 12, 1617-1623, PubMed: 96201641 (Pubitemid 26146285)
    • (1996) Oncogene , vol.12 , Issue.8 , pp. 1617-1623
    • Mujoo, K.1    Maneval, D.C.2    Anderson, S.C.3    Gutterman, J.U.4
  • 36
    • 0033543077 scopus 로고    scopus 로고
    • A phase I/II study of hepatic artery infusion with wtp53-CMV-Ad in metastatic malignant liver tumours
    • DOI 10.1089/10430349950017383
    • Habib, N.A. et al. (1999) A phase I/II study of hepatic artery infusion with wtp53-CMV-Ad in metastatic malignant liver tumours. Hum Gene Ther 10, 2019-2034, PubMed: 99394512 (Pubitemid 29387916)
    • (1999) Human Gene Therapy , vol.10 , Issue.12 , pp. 2019-2034
    • Habib, N.A.1    Hodgson, H.2    Lemoine, N.3    Pignatelli, M.4
  • 37
    • 0028823836 scopus 로고
    • Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody
    • PubMed: 96016292
    • Deshane, J. et al. (1995) Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody. Gynecol Oncol 59, 8-14, PubMed: 96016292
    • (1995) Gynecol Oncol , vol.59 , pp. 8-14
    • Deshane, J.1
  • 39
    • 0034475166 scopus 로고    scopus 로고
    • Development of clinical trial of E1A gene therapy targeting HER-2/neu-overexpressing breast and ovarian cancer
    • Hung, M.C., Hortobagyi, G.N. and Ueno, N.T. (2000) Development of clinical trial of E1A gene therapy targeting HER-2/neu-overexpressing breast and ovarian cancer. Adv Exp Med Biol 465, 171-180, PubMed: 20270922 (Pubitemid 32193333)
    • (2000) Advances in Experimental Medicine and Biology , vol.465 , pp. 171-180
    • Hung, M.C.1    Hortobagyi, G.N.2    Ueno, N.T.3
  • 40
    • 0032504347 scopus 로고    scopus 로고
    • A Phase i multicenter study of E1A gene therapy for patients with metastatic breast cancer and epithelial ovarian cancer that overexpresses HER-2/neu or epithelial ovarian cancer
    • PubMed: 98386042
    • Hortobagyi, G.N., Hung, M.C. and Lopez-Berestein, G. (1998) A Phase I multicenter study of E1A gene therapy for patients with metastatic breast cancer and epithelial ovarian cancer that overexpresses HER-2/neu or epithelial ovarian cancer. Hum Gene Ther 9, 1775-1798, PubMed: 98386042
    • (1998) Hum Gene Ther , vol.9 , pp. 1775-1798
    • Hortobagyi, G.N.1    Hung, M.C.2    Lopez-Berestein, G.3
  • 42
    • 0031424510 scopus 로고    scopus 로고
    • Genetic prodrug activation therapy
    • DOI 10.1016/S1357-4310(97)01082-4
    • Rigg, A. and Sikora, K. (1997) Genetic prodrug activation therapy. Mol Med Today 3, 359-366, PubMed: 97415057 (Pubitemid 28119271)
    • (1997) Molecular Medicine Today , vol.3 , Issue.8 , pp. 359-366
    • Rigg, A.1    Sikora, K.2
  • 43
    • 0028108469 scopus 로고
    • Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase
    • PubMed: 94336734
    • Huber, B.E. et al. (1994) Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase. Proc Natl Acad Sci USA 91, 8302-8306, PubMed: 94336734
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8302-8306
    • Huber, B.E.1
  • 44
    • 0027483695 scopus 로고
    • The 'bystander effect': Tumor regression when a fraction of the tumor mass is genetically modified
    • Freeman, S.M. et al. PubMed: 94036810
    • Freeman, S.M. et al. (1993) The 'bystander effect': tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res 53, 5274-5283, PubMed: 94036810
    • (1993) Cancer Res , vol.53 , pp. 5274-5283
  • 45
    • 0032502844 scopus 로고    scopus 로고
    • Double suicide gene (cytosine deaminase and herpes simplex virus thymidine kinase) but not single gene transfer allows reliable elimination of tumor cells in vivo
    • Uckert, W. et al. (1998) Double suicide gene (cytosine deaminase and herpes simplex virus thymidine kinase) but not single gene transfer allows reliable elimination of tumor cells in vivo. Hum Gene Ther 9, 855-865, PubMed: 98241064 (Pubitemid 28197372)
    • (1998) Human Gene Therapy , vol.9 , Issue.6 , pp. 855-865
    • Uckert, W.1    Kammertons, T.2    Haack, K.3    Qin, Z.4    Gebert, J.5    Schendel, D.J.6    Blankenstein, T.7
  • 46
    • 0034483380 scopus 로고    scopus 로고
    • Suicide gene therapy of ovarian cancer: An experimental study in rats using retroviral-mediated transfer of herpes simplex virus thymidine kinase gene
    • Nagy, H.J. et al. (2000) Suicide gene therapy of ovarian cancer: an experimental study in rats using retroviral-mediated transfer of herpes simplex virus thymidine kinase gene. Anticancer Res 20, 4633-4638, PubMed: 21076753 (Pubitemid 32141829)
    • (2000) Anticancer Research , vol.20 , Issue.6 , pp. 4633-4638
    • Nagy, H.J.1    Panis, Y.2    Fabre, M.3    Klatzmann, D.4    Houssin, D.5    Soubrane, O.6
  • 49
    • 0033497865 scopus 로고    scopus 로고
    • Regional versus systemic delivery of recombinant vaccinia virus as suicide gene therapy for murine liver metastases
    • discussion 360-351, PubMed: 99421225
    • Gnant, M.F. et al. (1999) Regional versus systemic delivery of recombinant vaccinia virus as suicide gene therapy for murine liver metastases. Ann Surg 230, 352-360; discussion 360-351, PubMed: 99421225
    • (1999) Ann Surg , vol.230 , pp. 352-360
    • Gnant, M.F.1
  • 50
    • 0029076201 scopus 로고
    • Treatment of experimental human mesothelioma using adenovirus transfer of the herpes simplex thymidine kinase gene
    • PubMed: 95344282
    • Smythe, W.R. et al. (1995) Treatment of experimental human mesothelioma using adenovirus transfer of the herpes simplex thymidine kinase gene. Ann Surg 222, 78-86, PubMed: 95344282
    • (1995) Ann Surg , vol.222 , pp. 78-86
    • Smythe, W.R.1
  • 52
    • 0031941292 scopus 로고    scopus 로고
    • Regional 'pro-drug' gene therapy: Intravenous administration of an adenoviral vector expressing the E. coli cytosine deaminase gene and systemic administration of 5-fluorocytosine suppresses growth of hepatic metastasis of colon carcinoma
    • Topf, N. et al. (1998) Regional 'pro-drug' gene therapy: intravenous administration of an adenoviral vector expressing the E. coli cytosine deaminase gene and systemic administration of 5-fluorocytosine suppresses growth of hepatic metastasis of colon carcinoma. Gene Ther 5, 507-513, PubMed: 98276759 (Pubitemid 28200643)
    • (1998) Gene Therapy , vol.5 , Issue.4 , pp. 507-513
    • Topf, N.1    Worgall, S.2    Hackett, N.R.3    Crystal, R.G.4
  • 53
    • 0033914616 scopus 로고    scopus 로고
    • Combined suicide gene therapy for human colon cancer cells using adenovirus-mediated transfer of Escherichia coli cytosine deaminase gene and Escherichia coli uracil phosphoribosyltransferase gene with 5-fluorocytosine
    • Koyama, F. et al. (2000) Combined suicide gene therapy for human colon cancer cells using adenovirus-mediated transfer of escherichia coli cytosine deaminase gene and Escherichia coli uracil phosphoribosyltransferase gene with 5-fluorocytosine. Cancer Gene Ther 7, 1015-1022, PubMed: 20371872 (Pubitemid 30483481)
    • (2000) Cancer Gene Therapy , vol.7 , Issue.7 , pp. 1015-1022
    • Koyama, F.1    Sawada, H.2    Hirao, T.3    Fujii, H.4    Hamada, H.5    Nakano, H.6
  • 54
    • 0035158045 scopus 로고    scopus 로고
    • In vivo gene therapy for colon cancer using adenovirus-mediated, transfer of the fusion gene cytosine deaminase and uracil phosphoribosyltransferase
    • DOI 10.1038/sj.gt.3301557
    • Chung-Faye, G.A. et al. (2001) In vivo gene therapy for colon cancer using adenovirus-mediated, transfer of the fusion gene cytosine deaminase and uracil phosphoribosyltransferase. Gene Ther 8, 1547-1554, PubMed: 21560682 (Pubitemid 33061893)
    • (2001) Gene Therapy , vol.8 , Issue.20 , pp. 1547-1554
    • Chung-Faye, G.A.1    Chen, M.J.2    Green, N.K.3    Burton, A.4    Anderson, D.5    Mautner, V.6    Searle, P.F.7    Kerr, D.J.8
  • 55
    • 0034885426 scopus 로고    scopus 로고
    • Phase II study of direct intralesional gene transfer of Allovectin-7, an HLA-B7/β2-microglobulin DNA-liposome complex, in patients with metastatic melanoma
    • Stopeck, A.T. et al. (2001) Phase II study of direct intralesional gene transfer of allovectin-7, an HLA-B7/beta2-microglobulin DNA-liposome complex, in patients with metastatic melanoma. Clin Cancer Res 7, 2285-2291, PubMed: 21381723 (Pubitemid 32751626)
    • (2001) Clinical Cancer Research , vol.7 , Issue.8 , pp. 2285-2291
    • Stopeck, A.T.1    Jones, A.2    Hersh, E.M.3    Thompson, J.A.4    Finucane, D.M.5    Gutheil, J.C.6    Gonzalez, R.7
  • 56
    • 0031426985 scopus 로고    scopus 로고
    • Advances in the biological therapy and gene therapy of malignant disease
    • Hersh, E.M. and Stopeck, A.T. (1997) Advances in the biological therapy and gene therapy of malignant disease. Clin Cancer Res 3, 2623-2629, PubMed: 99163408 (Pubitemid 28133117)
    • (1997) Clinical Cancer Research , vol.3 , Issue.12 , pp. 2623-2629
    • Hersh, E.M.1    Stopeck, A.T.2
  • 57
    • 0031435653 scopus 로고    scopus 로고
    • Reversal of tumor-induced immunosuppression: A new approach to cancer therapy
    • DOI 10.1097/00002371-199705000-00001
    • Wojtowicz-Praga, S. (1997) Reversal of tumor-induced immunosuppression: a new approach to cancer therapy. J Immunother 20, 165-177, PubMed: 97325401 (Pubitemid 28011544)
    • (1997) Journal of Immunotherapy , vol.20 , Issue.3 , pp. 165-177
    • Wojtowicz-Praga, S.1
  • 58
    • 0029202841 scopus 로고
    • Immunotherapy and gene therapy of cancer
    • PubMed: 95185382
    • Ettinghausen, S.E. and Rosenberg, S.A. (1995) Immunotherapy and gene therapy of cancer. Adv Surg 28, 223-254, PubMed: 95185382
    • (1995) Adv Surg , vol.28 , pp. 223-254
    • Ettinghausen, S.E.1    Rosenberg, S.A.2
  • 59
    • 0035902080 scopus 로고    scopus 로고
    • Progress in human tumour immunology and immunotherapy
    • DOI 10.1038/35077246
    • Rosenberg, S.A. (2001) Progress in human tumour immunology and immunotherapy. Nature 411, 380-384, PubMed: 21256223 (Pubitemid 32467048)
    • (2001) Nature , vol.411 , Issue.6835 , pp. 380-384
    • Rosenberg, S.A.1
  • 60
    • 84867567206 scopus 로고    scopus 로고
    • Antitumour immune responses
    • DOI: 10.1017/S1462399403005623
    • Mitra, R., Singh, S. and Khar, A. (2003) Antitumour immune responses. Exp. Rev. Mol. Med. 5, DOI: 10.1017/S1462399403005623
    • (2003) Exp. Rev. Mol. Med. , vol.5
    • Mitra, R.1    Singh, S.2    Khar, A.3
  • 61
    • 0033103021 scopus 로고    scopus 로고
    • A new era for cancer immunotherapy based on the genes that encode cancer antigens
    • Rosenberg, S.A. (1999) A new era for cancer immunotherapy based on the genes that encode cancer antigens. Immunity 10, 281-287, PubMed: 99219178 (Pubitemid 29165283)
    • (1999) Immunity , vol.10 , Issue.3 , pp. 281-287
    • Rosenberg, S.A.1
  • 62
    • 0034779682 scopus 로고    scopus 로고
    • Gene gun-mediated oral mucosal transfer of interleukin 12 cDNA coupled with an irradiated melanoma vaccine in a hamster model: Successful treatment of oral melanoma and distant skin lesion
    • DOI 10.1038/sj.cgt.7700363
    • Wang, J. et al. (2001) Gene gun-mediated oral mucosal transfer of interleukin 12 cDNA coupled with an irradiated melanoma vaccine in a hamster model: successful treatment of oral melanoma and distant skin lesion. Cancer Gene Ther 8, 705-712, PubMed: 21543318 (Pubitemid 32983126)
    • (2001) Cancer Gene Therapy , vol.8 , Issue.10 , pp. 705-712
    • Wang, J.1    Murakami, T.2    Hakamata, Y.3    Ajiki, T.4    Jinbu, Y.5    Akasaka, Y.6    Ohtsuki, M.7    Nakagawa, H.8    Kobayashi, E.9
  • 65
    • 0035831628 scopus 로고    scopus 로고
    • Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: Outcome of a phase i study
    • PubMed: 21319759
    • Kang, W.K. et al. (2001) Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: outcome of a phase I study. Hum Gene Ther 12, 671-684, PubMed: 21319759
    • (2001) Hum Gene Ther , vol.12 , pp. 671-684
    • Kang, W.K.1
  • 68
    • 0031689298 scopus 로고    scopus 로고
    • Irradiated tumor cells adenovirally engineered to secrete granulocyte/macrophage-colony-stimulating factor establish antitumor immunity and eliminate pre-existing tumors in syngeneic mice
    • DOI 10.1007/s002620050506
    • Nagai, E. et al. (1998) Irradiated tumor cells adenovirally engineered to secrete granulocyte/macrophage-colony-stimulating factor establish antitumor immunity and eliminate pre-existing tumors in syngeneic mice. Cancer Immunol Immunother 47, 72-80, PubMed: 98440051 (Pubitemid 28442706)
    • (1998) Cancer Immunology Immunotherapy , vol.47 , Issue.2 , pp. 72-80
    • Nagai, E.1    Ogawa, T.2    Kielian, T.3    Ikubo, A.4    Suzuki, T.5
  • 69
    • 0032880649 scopus 로고    scopus 로고
    • Human tumor antigens for cancer vaccine development
    • DOI 10.1111/j.1600-065X.1999.tb01331.x
    • Wang, R.F. and Rosenberg, S.A. (1999) Human tumor antigens for cancer vaccine development. Immunol Rev 170, 85-100, PubMed: 20032578 (Pubitemid 29490747)
    • (1999) Immunological Reviews , vol.170 , pp. 85-100
    • Wang, R.-F.1    Rosenberg, S.A.2
  • 70
    • 0030856119 scopus 로고    scopus 로고
    • Dendritic cells genetically modified with an adenovirus vector encoding the cDNA for a model antigen induce protective and therapeutic antitumor immunity
    • DOI 10.1084/jem.186.8.1247
    • Song, W. et al. (1997) Dendritic cells genetically modified with an adenovirus vector encoding the cDNA for a model antigen induce protective and therapeutic antitumor immunity. J Exp Med 186, 1247-1256, PubMed: 97477408 (Pubitemid 27469020)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.8 , pp. 1247-1256
    • Song, W.1    Kong, H.-L.2    Carpenter, H.3    Torii, H.4    Granstein, R.5    Rafii, S.6    Moore, M.A.S.7    Crystal, R.G.8
  • 73
    • 0034551730 scopus 로고    scopus 로고
    • Phase i study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses
    • PubMed: 20551342
    • Marshall, J.L. et al. (2000) Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti- carcinoembryonic antigen immune responses. J Clin Oncol 18, 3964-3973, PubMed: 20551342
    • (2000) J Clin Oncol , vol.18 , pp. 3964-3973
    • Marshall, J.L.1
  • 74
    • 0034779612 scopus 로고    scopus 로고
    • Combined IL-12 and GM-CSF gene therapy for murine hepatocellular carcinoma
    • DOI 10.1038/sj.cgt.7700375
    • Wang, Z. et al. (2001) Combined IL-12 and GM-CSF gene therapy for murine hepatocellular carcinoma. Cancer Gene Ther 8, 751-758, PubMed: 21543323 (Pubitemid 32983131)
    • (2001) Cancer Gene Therapy , vol.8 , Issue.10 , pp. 751-758
    • Wang, Z.1    Qiu, S.-J.2    Ye, S.-L.3    Tang, Z.-Y.4    Xiao, X.5
  • 75
    • 0034925044 scopus 로고    scopus 로고
    • Transgenic expression of CD40L and interleukin-2 induces an autologous antitumor immune response in patients with non-Hodgkin's lymphoma
    • DOI 10.1038/sj.cgt.7700315
    • Takahashi, S. et al. (2001) Transgenic expression of CD40L and interleukin-2 induces an autologous antitumor immune response in patients with non-Hodgkin's lymphoma. Cancer Gene Ther 8, 378-387, PubMed: 21369498 (Pubitemid 32685645)
    • (2001) Cancer Gene Therapy , vol.8 , Issue.5 , pp. 378-387
    • Takahashi, S.1    Yotnda, P.2    Rousseau, R.F.3    Mei, Z.4    Smith, S.5    Rill, D.6    Younes, A.7    Brenner, M.K.8
  • 77
    • 0030332823 scopus 로고    scopus 로고
    • Replicating viruses as selective cancer therapeutics
    • DOI 10.1016/S1357-4310(97)81456-6, PII S1357431096100502
    • Kirn, D.H. and McCormick, F. (1996) Replicating viruses as selective cancer therapeutics. Mol Med Today 2, 519-527, PubMed: 97168176 (Pubitemid 126376968)
    • (1996) Molecular Medicine Today , vol.2 , Issue.12 , pp. 519-527
    • Kirn, D.H.1    McCormick, F.2
  • 78
    • 0025864440 scopus 로고
    • Experimental therapy of human glioma by means of a genetically engineered virus mutant
    • Martuza, R.L. et al. (1991) Experimental therapy of human glioma by means of a genetically engineered virus mutant. Science 252, 854-856, PubMed: 91227914 (Pubitemid 121000529)
    • (1991) Science , vol.252 , Issue.5007 , pp. 854-856
    • Martuza, R.L.1    Malick, A.2    Markert, J.M.3    Ruffner, K.L.4    Coen, D.M.5
  • 80
    • 0030917202 scopus 로고    scopus 로고
    • ONYX-015, an E1b gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
    • DOI 10.1038/nm0697-639
    • Heise, C. et al. (1997) ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nat Med 3, 639-645, PubMed: 97319587 (Pubitemid 27264973)
    • (1997) Nature Medicine , vol.3 , Issue.6 , pp. 639-645
    • Heise, C.1    Sampson-Johannes, A.2    Williams, A.3    McCormick, F.4    Von Hoff, D.D.5    Kirn, D.H.6
  • 81
    • 0033623250 scopus 로고    scopus 로고
    • Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015)
    • PubMed: 20473283
    • Ries, S.J. et al. (2000) Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015). Nat Med 6, 1128-1133, PubMed: 20473283
    • (2000) Nat Med , vol.6 , pp. 1128-1133
    • Ries, S.J.1
  • 84
    • 0033693231 scopus 로고    scopus 로고
    • Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A phase II trial
    • PubMed: 20552161
    • Nemunaitis, J. et al. (2000) Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial. Cancer Res 60, 6359-6366, PubMed: 20552161
    • (2000) Cancer Res , vol.60 , pp. 6359-6366
    • Nemunaitis, J.1
  • 85
    • 0033199929 scopus 로고    scopus 로고
    • Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207
    • DOI 10.1089/10430349950017211
    • Walker, J.R. et al. (1999) Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207. Hum Gene Ther 10, 2237-2243, PubMed: 99426542 (Pubitemid 29416302)
    • (1999) Human Gene Therapy , vol.10 , Issue.13 , pp. 2237-2243
    • Walker, J.R.1    McGeagh, K.G.2    Sundaresan, P.3    Jorgensen, T.J.4    Rabkin, S.D.5    Martuza, R.L.6
  • 88
    • 0030790684 scopus 로고    scopus 로고
    • Prostate attenuated replication competent adenovirus (ARCA) CN706: A selective cytotoxic for prostate-specific antigen-positive prostate cancer cells
    • Rodriguez, R. et al. (1997) Prostate attenuated replication competent adenovirus (ARCA) CN706: a selective cytotoxic for prostate-specific antigen-positive prostate cancer cells. Cancer Res 57, 2559-2563, PubMed: 97349049 (Pubitemid 27283756)
    • (1997) Cancer Research , vol.57 , Issue.13 , pp. 2559-2563
    • Rodriguez, R.1    Schuur, E.R.2    Lim, H.Y.3    Henderson, G.A.4    Simons, J.W.5    Henderson, D.R.6
  • 89
    • 0033805534 scopus 로고    scopus 로고
    • Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen
    • PubMed: 20453313
    • Kurihara, T. et al. (2000) Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen. J Clin Invest 106, 763-771, PubMed: 20453313
    • (2000) J Clin Invest , vol.106 , pp. 763-771
    • Kurihara, T.1
  • 91
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • PubMed: 72008493
    • Folkman, J. (1971) Tumor angiogenesis: therapeutic implications. N Engl J Med 285, 1182-1186, PubMed: 72008493
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 92
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • PubMed: 96071368
    • Folkman, J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1, 27-31, PubMed: 96071368
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 93
    • 0026846928 scopus 로고
    • The role of angiogenesis in tumor growth
    • PubMed: 92329736
    • Folkman, J. (1992) The role of angiogenesis in tumor growth. Semin Cancer Biol 3, 65-71, PubMed: 92329736
    • (1992) Semin Cancer Biol , vol.3 , pp. 65-71
    • Folkman, J.1
  • 94
    • 0030242225 scopus 로고    scopus 로고
    • Fighting cancer by attacking its blood supply
    • PubMed: 96327182
    • Folkman, J. (1996) Fighting cancer by attacking its blood supply. Sci Am 275, 150-154, PubMed: 96327182
    • (1996) Sci Am , vol.275 , pp. 150-154
    • Folkman, J.1
  • 95
    • 0032747902 scopus 로고    scopus 로고
    • Factors promoting tumor angiogenesis
    • PubMed: 20060352
    • Beckner, M.E. (1999) Factors promoting tumor angiogenesis. Cancer Invest 17, 594-623, PubMed: 20060352
    • (1999) Cancer Invest , vol.17 , pp. 594-623
    • Beckner, M.E.1
  • 96
    • 0034666258 scopus 로고    scopus 로고
    • Progress in antiangiogenic gene therapy of cancer
    • PubMed: 20458923
    • Feldman, A.L. and Libutti, S.K. (2000) Progress in antiangiogenic gene therapy of cancer. Cancer 89, 1181-1194, PubMed: 20458923
    • (2000) Cancer , vol.89 , pp. 1181-1194
    • Feldman, A.L.1    Libutti, S.K.2
  • 98
    • 0032502843 scopus 로고    scopus 로고
    • Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor
    • PubMed: 98241061
    • Kong, H.L. et al. (1998) Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor. Hum Gene Ther 9, 823-833, PubMed: 98241061
    • (1998) Hum Gene Ther , vol.9 , pp. 823-833
    • Kong, H.L.1
  • 102
    • 0032031748 scopus 로고    scopus 로고
    • Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases
    • Cao, Y. et al. (1998) Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases. J Clin Invest 101, 1055-1063, PubMed: 98153232 (Pubitemid 28125284)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.5 , pp. 1055-1063
    • Cao, Y.1    O'Reilly, M.S.2    Marshall, B.3    Flynn, E.4    Ji, R.-W.5    Folkman, J.6
  • 107
    • 0030701975 scopus 로고    scopus 로고
    • Combination therapy with suicide and cytokine genes for hepatic metastases of lung cancer
    • PubMed: 98033300
    • Kwong, Y.L. et al. (1997) Combination therapy with suicide and cytokine genes for hepatic metastases of lung cancer. Chest 112, 1332-1337, PubMed: 98033300
    • (1997) Chest , vol.112 , pp. 1332-1337
    • Kwong, Y.L.1
  • 108
    • 0033857586 scopus 로고    scopus 로고
    • Combined suicide and cytokine gene therapy for peritoneal carcinomatosis
    • PubMed: 20400365
    • Lechanteur, C. et al. (2000) Combined suicide and cytokine gene therapy for peritoneal carcinomatosis. Gut 47, 343-348, PubMed: 20400365
    • (2000) Gut , vol.47 , pp. 343-348
    • Lechanteur, C.1
  • 109
    • 0031262574 scopus 로고    scopus 로고
    • Inhibition of establishment of hepatic metastasis in mice by combination gene therapy using both herpes simplex virus-thymidine kinase and granulocyte macrophage-colony stimulating factor genes in murine colon cancer
    • Hayashi, S. et al. (1997) Inhibition of establishment of hepatic metastasis in mice by combination gene therapy using both herpes simplex virus-thymidine kinase and granulocyte macrophage-colony stimulating factor genes in murine colon cancer. Cancer Gene Ther 4, 339-344, PubMed: 98072901 (Pubitemid 127667125)
    • (1997) Cancer Gene Therapy , vol.4 , Issue.6 , pp. 339-344
    • Hayashi, S.1    Emi, N.2    Yokoyama, I.3    Namii, Y.4    Uchida, K.5    Takagi, H.6
  • 111
    • 0030052050 scopus 로고    scopus 로고
    • Radiosensitization by 5-fluorocytosine of human colorectal carcinoma cells in culture transduced with cytosine deaminase gene
    • Khil, M.S. et al. (1996) Radiosensitization by 5-fluorocytosine of human colorectal carcinoma cells in culture transduced with cytosine deaminase gene. Clin Cancer Res 2, 53-57, PubMed: 99034992 (Pubitemid 26042179)
    • (1996) Clinical Cancer Research , vol.2 , Issue.1 , pp. 53-57
    • Khil, M.S.1    Kim, J.H.2    Mullen, C.A.3    Kim, S.H.4    Freytag, S.O.5
  • 113
    • 0034652615 scopus 로고    scopus 로고
    • ONYX-015 works synergistically with chemotherapy in lung cancer cell lines and primary cultures freshly made from lung cancer patients
    • You, L., Yang, C.T. and Jablons, D.M. (2000) ONYX-015 works synergistically with chemotherapy in lung cancer cell lines and primary cultures freshly made from lung cancer patients. Cancer Res 60, 1009-1013, PubMed: 20168634 (Pubitemid 30129538)
    • (2000) Cancer Research , vol.60 , Issue.4 , pp. 1009-1013
    • You, L.1    Yang, C.-T.2    Jablons, D.M.3
  • 115
    • 0031264226 scopus 로고    scopus 로고
    • Cisplatin-based interferon γ gene therapy of murine ovarian carcinoma
    • Son, K. (1997) Cisplatin-based interferon gamma gene therapy of murine ovarian carcinoma. Cancer Gene Ther 4, 391-396, PubMed: 98072908 (Pubitemid 127667132)
    • (1997) Cancer Gene Therapy , vol.4 , Issue.6 , pp. 391-396
    • Son, K.1
  • 116
    • 0034922608 scopus 로고    scopus 로고
    • Cisplatin chemotherapy plus adenoviral p53 gene therapy in EBV-positive and -negative nasopharyngeal carcinoma
    • DOI 10.1038/sj.cgt.7700319
    • Weinrib, L. et al. (2001) Cisplatin chemotherapy plus adenoviral p53 gene therapy in EBV-positive and-negative nasopharyngeal carcinoma. Cancer Gene Ther 8, 352-360, PubMed: 21369495 (Pubitemid 32685642)
    • (2001) Cancer Gene Therapy , vol.8 , Issue.5 , pp. 352-360
    • Weinrib, L.1    Li, J.-H.2    Donovan, J.3    Huang, D.4    Liu, F.-F.5
  • 117
    • 0034814353 scopus 로고    scopus 로고
    • Synergistic inhibition of human lung cancer cell growth by adenovirus-mediated wild-type p53 gene transfer in combination with docetaxel and radiation therapeutics in vitro and in vivo
    • Nishizaki, M. et al. (2001) Synergistic inhibition of human lung cancer cell growth by adenovirus-mediated wild-type p53 gene transfer in combination with docetaxel and radiation therapeutics in vitro and in vivo. Clin Cancer Res 7, 2887-2897, PubMed: 21439144 (Pubitemid 32911399)
    • (2001) Clinical Cancer Research , vol.7 , Issue.9 , pp. 2887-2897
    • Nishizaki, M.1    Meyn, R.E.2    Levy, L.B.3    Atkinson, E.N.4    White, R.A.5    Roth, J.A.6    Ji, L.7
  • 118
    • 0029075603 scopus 로고
    • Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas
    • PubMed: 95273403
    • Singh, R.K. et al. (1995) Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas. Proc Natl Acad Sci USA 92, 4562-4566, PubMed: 95273403
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4562-4566
    • Singh, R.K.1
  • 120
    • 0034264453 scopus 로고    scopus 로고
    • Gene therapy: Public education
    • PubMed: 20442623
    • Verma, I.M. (2000) Gene therapy: public education. Mol Ther 2, 177, PubMed: 20442623
    • (2000) Mol Ther , vol.2 , pp. 177
    • Verma, I.M.1
  • 122
    • 0034684471 scopus 로고    scopus 로고
    • Chemosensitisation of malignant melanoma by BCL2 antisense therapy
    • PubMed: 20544370
    • Jansen, B. et al. (2000) Chemosensitisation of malignant melanoma by BCL2 antisense therapy. Lancet 356, 1728-1733, PubMed: 20544370
    • (2000) Lancet , vol.356 , pp. 1728-1733
    • Jansen, B.1
  • 123
    • 0034926056 scopus 로고    scopus 로고
    • Comparative analysis of IFN-γ B7.1 and antisense TGF-β gene transfer on the tumorigenicity of a poorly immunogenic metastatic mammary carcinoma
    • DOI 10.1007/s002620100197
    • Wu, R.S. et al. (2001) Comparative analysis of IFN-gamma B7.1 and antisense TGF-beta gene transfer on the tumorigenicity of a poorly immunogenic metastatic mammary carcinoma. Cancer Immunol Immunother 50, 229-240, PubMed: 21390644 (Pubitemid 32662526)
    • (2001) Cancer Immunology, Immunotherapy , vol.50 , Issue.5 , pp. 229-240
    • Wu, R.S.1    Kobie, J.J.2    Besselsen, D.G.3    Fong, T.C.4    Mack, V.D.5    McEarchern, J.A.6    Akporiaye, E.T.7
  • 126
    • 0031828490 scopus 로고    scopus 로고
    • Antisense oligonucleotide specific for transforming growth factor-beta 1 inhibit both in vitro and in vivo growth of MBT-2 murine bladder cancer
    • PubMed: 98338091
    • Tzai, T.S. et al. (1998) Antisense oligonucleotide specific for transforming growth factor-beta 1 inhibit both in vitro and in vivo growth of MBT-2 murine bladder cancer. Anticancer Res 18, 1585-1589, PubMed: 98338091
    • (1998) Anticancer Res , vol.18 , pp. 1585-1589
    • Tzai, T.S.1
  • 127
    • 0033969415 scopus 로고    scopus 로고
    • Gene therapy strategies for colon cancer
    • PubMed: 20119522
    • Chung-Faye, G.A. et al. (2000) Gene therapy strategies for colon cancer. Mol Med Today 6, 82-87, PubMed: 20119522
    • (2000) Mol Med Today , vol.6 , pp. 82-87
    • Chung-Faye, G.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.