Polyurethane modified with an antithrombin-heparin complex via polyethylene oxide linker/spacers: Influence of PEO molecular weight and PEO-ATH bond on catalytic and direct anticoagulant functions

Journal of Biomedical Materials Research - Part A

Volumn 100 A, Issue 10, 2012, Pages 2821-2828

  Sask, Kyla N ^a   Berry, Leslie R ^b   Chan, Anthony K C ^a,b   Brash, John L ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

anticoagulant; antithrombin; heparin; polyethylene oxide; polyurethane

Indexed keywords

ANTICOAGULANT; ANTICOAGULANT PROPERTIES; ANTITHROMBIN; END GROUPS; FIBRINOGEN ADSORPTION; FUNCTIONALIZED; HEPARIN; ISOCYANATE GROUP; N-HYDROXYSUCCINIMIDE; PEO MOLECULAR WEIGHT; RADIOLABELING; SEGMENTED POLYURETHANES; SURFACE DENSITY; THROMBIN INHIBITION; WATER CONTACT ANGLE;

CONTACT ANGLE; ENZYMES; MOLECULAR WEIGHT; POLYETHYLENE OXIDES; POLYETHYLENES; POLYSACCHARIDES; POLYURETHANES; THERMOPLASTICS;

ADSORPTION;

ANTICOAGULANT AGENT; ANTITHROMBIN; ANTITHROMBIN HEPARIN; FIBRINOGEN; HEPARIN; ISOCYANIC ACID DERIVATIVE; MACROGOL; N HYDROXYSUCCINIMIDE; POLYURETHAN; THROMBIN; UNCLASSIFIED DRUG;

ANTICOAGULATION; ARTICLE; CATALYSIS; CONTACT ANGLE; HUMAN; HYDROPHILICITY; ISOTOPE LABELING; MOLECULAR WEIGHT;

ADSORPTION; ANTICOAGULANTS; ANTITHROMBINS; CATALYSIS; FIBRINOGEN; HEPARIN; HUMANS; MOLECULAR WEIGHT; POLYETHYLENE GLYCOLS; POLYURETHANES; PROTEIN BINDING; SURFACE PROPERTIES; WATER;

EID: 84865615828     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34218     Document Type: Article

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