Surface modification with an antithrombin-heparin complex for anticoagulation: Studies on a model surface with gold as substrate

Acta Biomaterialia

Volumn 6, Issue 8, 2010, Pages 2911-2919

  Sask, Kyla N ^a   Zhitomirsky, Igor ^a   Berry, Leslie R ^b   Chan, Anthony K C ^a,b   Brash, John L ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Antithrombin; Blood compatibility; Gold; Heparin; Polyethylene oxide

Indexed keywords

BLOOD; CHEMISORPTION; GOLD COMPOUNDS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYETHYLENES; PROTEINS; SURFACE TREATMENT; X RAY PHOTOELECTRON SPECTROSCOPY;

ANTI-COAGULATION; ANTITHROMBIN; BLOOD COMPATIBILITY; COVALENT COMPLEX; DITHIOBIS-SUCCINIMIDYL PROPIONATE; GOLD; IMMOBILISATION; MODEL SURFACE; MODIFIED SURFACES; SURFACE-MODIFICATION;

POLYSACCHARIDES;

3,3' DITHIOBIS(SUCCINIMIDYL PROPIONATE); ANTITHROMBIN; BIOMATERIAL; GOLD; HEPARIN; MACROGOL; PROTEIN; SODIUM IODIDE I 131; WATER; ANTICOAGULANT AGENT; FIBRINOGEN; PLASMA PROTEIN; RADIOACTIVE IODINE;

ADSORPTION; ANTICOAGULATION; ARTICLE; BIOCOMPATIBILITY; BLOOD SAMPLING; CHEMICAL MODIFICATION; COMPLEX FORMATION; CONTACT ANGLE; CONTROLLED STUDY; CROSS LINKING; DENSITY GRADIENT; DRUG BINDING; DRUG MECHANISM; ELLIPSOMETRY; ENZYME SUBSTRATE; HEPARINIZATION; HUMAN; HUMAN EXPERIMENT; IMMOBILIZATION; IMMUNOBLOTTING; MOLECULE; NORMAL HUMAN; PRIORITY JOURNAL; QUARTZ CRYSTAL MICROBALANCE; RADIOIODINATION; SURFACE MODIFICATION; SURFACE PROPERTY; X RAY PHOTOELECTRON SPECTROSCOPY; BLOOD CLOTTING; CHEMISTRY; DRUG EFFECT; MATERIALS TESTING; METABOLISM; METHODOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; WESTERN BLOTTING;

ADSORPTION; ANTICOAGULANTS; ANTITHROMBINS; BLOOD COAGULATION; BLOOD PROTEINS; BLOTTING, WESTERN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FIBRINOGEN; GOLD; HEPARIN; HUMANS; IODINE RADIOISOTOPES; MATERIALS TESTING; PHOTOELECTRON SPECTROSCOPY; SURFACE PROPERTIES; WATER;

EID: 77956635746     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2010.02.043     Document Type: Article

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