메뉴 건너뛰기




Volumn 14, Issue 5, 2012, Pages 569-578

Metabolic engineering of d-xylose pathway in Clostridium beijerinckii to optimize solvent production from xylose mother liquid

Author keywords

Clostridium beijerinckii; D xylose utilization; Xylose mother liquid; XylR inactivation; XylT overexpression

Indexed keywords

BUILDING BLOCKES; CLOSTRIDIUM BEIJERINCKII; D-XYLOSE; HIGHER YIELD; LIGNOCELLULOSIC MATERIAL; OVER-EXPRESSION; PENTOSE SUGARS; SOLVENT PRODUCTION; WILD-TYPE STRAIN; XYLR INACTIVATION;

EID: 84865613048     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2012.05.003     Document Type: Article
Times cited : (99)

References (54)
  • 2
    • 0034071629 scopus 로고    scopus 로고
    • Metabolic engineering applications to renewable resource utilization
    • Aristidou A., Penttila M. Metabolic engineering applications to renewable resource utilization. Curr. Opin. Biotechnol. 2000, 11:187-198.
    • (2000) Curr. Opin. Biotechnol. , vol.11 , pp. 187-198
    • Aristidou, A.1    Penttila, M.2
  • 4
    • 0001441208 scopus 로고
    • Effect of butanol challenge and temperature on lipid composition and membrane fluidity of butanol-tolerant Clostridium acetobutylicum
    • Baer S.H., Blaschek H.P., Smith T.L. Effect of butanol challenge and temperature on lipid composition and membrane fluidity of butanol-tolerant Clostridium acetobutylicum. Appl. Environ. Microbiol. 1987, 53:2854-2861.
    • (1987) Appl. Environ. Microbiol. , vol.53 , pp. 2854-2861
    • Baer, S.H.1    Blaschek, H.P.2    Smith, T.L.3
  • 5
    • 79952910616 scopus 로고    scopus 로고
    • Enzyme mechanism as a kinetic control element for designing synthetic biofuel pathways
    • Bond-Watts B.B., Bellerose R.J., Chang M.C. Enzyme mechanism as a kinetic control element for designing synthetic biofuel pathways. Nat. Chem. Biol. 2011, 7:222-227.
    • (2011) Nat. Chem. Biol. , vol.7 , pp. 222-227
    • Bond-Watts, B.B.1    Bellerose, R.J.2    Chang, M.C.3
  • 6
    • 79551621095 scopus 로고    scopus 로고
    • Xylitol production from xylose mother liquor: a novel strategy that combines the use of recombinant Bacillus subtilis and Candida maltosa
    • Cheng H., Wang B., Lv J., Jiang M., Lin S., Deng Z. Xylitol production from xylose mother liquor: a novel strategy that combines the use of recombinant Bacillus subtilis and Candida maltosa. Microb. Cell Fact. 2011, 10:5.
    • (2011) Microb. Cell Fact. , vol.10 , pp. 5
    • Cheng, H.1    Wang, B.2    Lv, J.3    Jiang, M.4    Lin, S.5    Deng, Z.6
  • 7
    • 0028877211 scopus 로고
    • Contributions of Xylr, Ccpa and Hpr to catabolite repression of the Xyl operon in Bacillus subtilis
    • Dahl M.K., Hillen W. Contributions of Xylr, Ccpa and Hpr to catabolite repression of the Xyl operon in Bacillus subtilis. FEMS Microbiol. Lett. 1995, 132:79-83.
    • (1995) FEMS Microbiol. Lett. , vol.132 , pp. 79-83
    • Dahl, M.K.1    Hillen, W.2
  • 8
    • 79951565301 scopus 로고    scopus 로고
    • Design, construction and characterization of a set of insulated bacterial promoters
    • Davis J.H., Rubin A.J., Sauer R.T. Design, construction and characterization of a set of insulated bacterial promoters. Nucleic Acids Res. 2011, 39:1131-1141.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 1131-1141
    • Davis, J.H.1    Rubin, A.J.2    Sauer, R.T.3
  • 9
    • 0031862665 scopus 로고    scopus 로고
    • New insights and novel developments in clostridial acetone/butanol/isopropanol fermentation
    • Durre P. New insights and novel developments in clostridial acetone/butanol/isopropanol fermentation. Appl. Microbiol. Biotechnol. 1998, 49:639-648.
    • (1998) Appl. Microbiol. Biotechnol. , vol.49 , pp. 639-648
    • Durre, P.1
  • 10
    • 38149030843 scopus 로고    scopus 로고
    • Biobutanol: an attractive biofuel
    • Durre P. Biobutanol: an attractive biofuel. Biotechnol. J. 2007, 2:1525-1534.
    • (2007) Biotechnol. J. , vol.2 , pp. 1525-1534
    • Durre, P.1
  • 11
    • 41349120749 scopus 로고    scopus 로고
    • Fermentative butanol production: bulk chemical and biofuel
    • Durre P. Fermentative butanol production: bulk chemical and biofuel. Ann. N.Y. Acad. Sci. 2008, 1125:353-362.
    • (2008) Ann. N.Y. Acad. Sci. , vol.1125 , pp. 353-362
    • Durre, P.1
  • 12
    • 34249993002 scopus 로고    scopus 로고
    • Butanol production from agricultural residues: Impact of degradation products on Clostridium beijerinckii growth and butanol fermentation
    • Ezeji T., Qureshi N., Blaschek H.P. Butanol production from agricultural residues: Impact of degradation products on Clostridium beijerinckii growth and butanol fermentation. Biotechnol. Bioeng. 2007, 97:1460-1469.
    • (2007) Biotechnol. Bioeng. , vol.97 , pp. 1460-1469
    • Ezeji, T.1    Qureshi, N.2    Blaschek, H.P.3
  • 13
    • 57049150206 scopus 로고    scopus 로고
    • Selection and optimization of microbial hosts for biofuels production
    • Fischer C.R., Klein-Marcuschamer D., Stephanopoulos G. Selection and optimization of microbial hosts for biofuels production. Metab. Eng. 2008, 10:295-304.
    • (2008) Metab. Eng. , vol.10 , pp. 295-304
    • Fischer, C.R.1    Klein-Marcuschamer, D.2    Stephanopoulos, G.3
  • 15
    • 0026596680 scopus 로고
    • Regulation of the Bacillus subtilis W23 xylose utilization operon: interaction of the Xyl repressor with the xyl operator and the inducer xylose
    • Gartner D., Degenkolb J., Ripperger J.A., Allmansberger R., Hillen W. Regulation of the Bacillus subtilis W23 xylose utilization operon: interaction of the Xyl repressor with the xyl operator and the inducer xylose. Mol. Gen. Genet. 1992, 232:415-422.
    • (1992) Mol. Gen. Genet. , vol.232 , pp. 415-422
    • Gartner, D.1    Degenkolb, J.2    Ripperger, J.A.3    Allmansberger, R.4    Hillen, W.5
  • 16
    • 0041527233 scopus 로고    scopus 로고
    • Development of a sensitive gene expression reporter system and an inducible promoter-repressor system for Clostridium acetobutylicum
    • Girbal L., Mortier-Barriere I., Raynaud F., Rouanet C., Croux C., Soucaille P. Development of a sensitive gene expression reporter system and an inducible promoter-repressor system for Clostridium acetobutylicum. Appl. Environ. Microbiol. 2003, 69:4985-4988.
    • (2003) Appl. Environ. Microbiol. , vol.69 , pp. 4985-4988
    • Girbal, L.1    Mortier-Barriere, I.2    Raynaud, F.3    Rouanet, C.4    Croux, C.5    Soucaille, P.6
  • 19
    • 31444433490 scopus 로고    scopus 로고
    • Synthetic promoter libraries--tuning of gene expression
    • Hammer K., Mijakovic I., Jensen P.R. Synthetic promoter libraries--tuning of gene expression. Trends Biotechnol. 2006, 24:53-55.
    • (2006) Trends Biotechnol. , vol.24 , pp. 53-55
    • Hammer, K.1    Mijakovic, I.2    Jensen, P.R.3
  • 21
    • 67650215053 scopus 로고    scopus 로고
    • Lignocellulose conversion to biofuels: current challenges, global perspectives
    • Himmel M.E., Bayer E.A. Lignocellulose conversion to biofuels: current challenges, global perspectives. Curr. Opin. Biotechnol. 2009, 20:316-317.
    • (2009) Curr. Opin. Biotechnol. , vol.20 , pp. 316-317
    • Himmel, M.E.1    Bayer, E.A.2
  • 22
    • 39049179484 scopus 로고    scopus 로고
    • Directed evolution of the 5'-untranslated region of the phoA gene in Escherichia coli simultaneously yields a stronger promoter and a stronger Shine-Dalgarno sequence
    • Huang X., Zhang X.E., Zhou Y.F., Zhang Z.P., Cass A.E.G. Directed evolution of the 5'-untranslated region of the phoA gene in Escherichia coli simultaneously yields a stronger promoter and a stronger Shine-Dalgarno sequence. Biotechnol. J. 2006, 1:1275-1282.
    • (2006) Biotechnol. J. , vol.1 , pp. 1275-1282
    • Huang, X.1    Zhang, X.E.2    Zhou, Y.F.3    Zhang, Z.P.4    Cass, A.E.G.5
  • 23
    • 68049142960 scopus 로고    scopus 로고
    • Disruption of the acetoacetate decarboxylase gene in solvent-producing Clostridium acetobutylicum increases the butanol ratio
    • Jiang Y., Xu C., Dong F., Yang Y., Jiang W., Yang S. Disruption of the acetoacetate decarboxylase gene in solvent-producing Clostridium acetobutylicum increases the butanol ratio. Metab. Eng. 2009, 11:284-291.
    • (2009) Metab. Eng. , vol.11 , pp. 284-291
    • Jiang, Y.1    Xu, C.2    Dong, F.3    Yang, Y.4    Jiang, W.5    Yang, S.6
  • 24
    • 74149091662 scopus 로고    scopus 로고
    • Sugar transporters in efficient utilization of mixed sugar substrates: current knowledge and outlook
    • Jojima T., Omumasaba C.A., Inui M., Yukawa H. Sugar transporters in efficient utilization of mixed sugar substrates: current knowledge and outlook. Appl. Microbiol. Biotechnol. 2010, 85:471-480.
    • (2010) Appl. Microbiol. Biotechnol. , vol.85 , pp. 471-480
    • Jojima, T.1    Omumasaba, C.A.2    Inui, M.3    Yukawa, H.4
  • 25
    • 0022970603 scopus 로고
    • Acetone-butanol fermentation revisited
    • Jones D.T., Woods D.R. Acetone-butanol fermentation revisited. Microbiol. Rev. 1986, 50:484-524.
    • (1986) Microbiol. Rev. , vol.50 , pp. 484-524
    • Jones, D.T.1    Woods, D.R.2
  • 26
    • 14544308803 scopus 로고    scopus 로고
    • AU-rich sequences within 5' untranslated leaders enhance translation and stabilize mRNA in Escherichia coli
    • Komarova A.V., Tchufistova L.S., Dreyfus M., Boni I.V. AU-rich sequences within 5' untranslated leaders enhance translation and stabilize mRNA in Escherichia coli. J Bacteriol. 2005, 187:1344-1349.
    • (2005) J Bacteriol. , vol.187 , pp. 1344-1349
    • Komarova, A.V.1    Tchufistova, L.S.2    Dreyfus, M.3    Boni, I.V.4
  • 27
    • 0028264818 scopus 로고
    • Catabolite repression of the Bacillus subtilis xyl operon involves a cis element functional in the context of an unrelated sequence, and glucose exerts additional xylR-dependent repression
    • Kraus A., Hueck C., Gartner D., Hillen W. Catabolite repression of the Bacillus subtilis xyl operon involves a cis element functional in the context of an unrelated sequence, and glucose exerts additional xylR-dependent repression. J. Bacteriol. 1994, 176:1738-1745.
    • (1994) J. Bacteriol. , vol.176 , pp. 1738-1745
    • Kraus, A.1    Hueck, C.2    Gartner, D.3    Hillen, W.4
  • 28
    • 77952239223 scopus 로고    scopus 로고
    • Butanol production by Clostridium beijerinckii ATCC 55025 from wheat bran
    • Liu Z., Ying Y., Li F., Ma C., Xu P. Butanol production by Clostridium beijerinckii ATCC 55025 from wheat bran. J. Ind. Microbiol. Biotechnol. 2010, 37:495-501.
    • (2010) J. Ind. Microbiol. Biotechnol. , vol.37 , pp. 495-501
    • Liu, Z.1    Ying, Y.2    Li, F.3    Ma, C.4    Xu, P.5
  • 29
    • 35148890697 scopus 로고    scopus 로고
    • Shuffling of promoters for multiple genes to optimize xylose fermentation in an engineered Saccharomyces cerevisiae strain
    • Lu C., Jeffries T. Shuffling of promoters for multiple genes to optimize xylose fermentation in an engineered Saccharomyces cerevisiae strain. Appl. Environ. Microbiol. 2007, 73:6072-6077.
    • (2007) Appl. Environ. Microbiol. , vol.73 , pp. 6072-6077
    • Lu, C.1    Jeffries, T.2
  • 30
    • 14744283496 scopus 로고
    • Expression of cloned homologous fermentative genes in Clostridium acetobutylicum ATCC 824
    • Mermelstein L.D., Welker N.E., Bennett G.N., Papoutsakis E.T. Expression of cloned homologous fermentative genes in Clostridium acetobutylicum ATCC 824. Biotechnology 1992, 10:190-195.
    • (1992) Biotechnology , vol.10 , pp. 190-195
    • Mermelstein, L.D.1    Welker, N.E.2    Bennett, G.N.3    Papoutsakis, E.T.4
  • 32
    • 77953022341 scopus 로고    scopus 로고
    • A comparative view of metabolite and substrate stress and tolerance in microbial bioprocessing: from biofuels and chemicals, to biocatalysis and bioremediation
    • Nicolaou S.A., et al. A comparative view of metabolite and substrate stress and tolerance in microbial bioprocessing: from biofuels and chemicals, to biocatalysis and bioremediation. Metab. Eng. 2010, 12:307-331.
    • (2010) Metab. Eng. , vol.12 , pp. 307-331
    • Nicolaou, S.A.1
  • 33
    • 0021957625 scopus 로고
    • Regulation and butanol inhibition of D-xylose and D-glucose uptake in Clostridium acetobutylicum
    • Ounine K., Petitdemange H., Raval G., Gay R. Regulation and butanol inhibition of D-xylose and D-glucose uptake in Clostridium acetobutylicum. Appl. Environ. Microbiol. 1985, 49:874-878.
    • (1985) Appl. Environ. Microbiol. , vol.49 , pp. 874-878
    • Ounine, K.1    Petitdemange, H.2    Raval, G.3    Gay, R.4
  • 34
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001, 29:e45.
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaffl, M.W.1
  • 35
    • 56349146406 scopus 로고    scopus 로고
    • Removal of fermentation inhibitors from alkaline peroxide pretreated and enzymatically hydrolyzed wheat straw: Production of butanol from hydrolysate using Clostridium beijerinckii in batch reactors
    • Qureshi N., Saha B.C., Hector R.E., Cotta M.A. Removal of fermentation inhibitors from alkaline peroxide pretreated and enzymatically hydrolyzed wheat straw: Production of butanol from hydrolysate using Clostridium beijerinckii in batch reactors. Biomass Bioenerg. 2008, 32:1353-1358.
    • (2008) Biomass Bioenerg. , vol.32 , pp. 1353-1358
    • Qureshi, N.1    Saha, B.C.2    Hector, R.E.3    Cotta, M.A.4
  • 36
    • 74049128960 scopus 로고    scopus 로고
    • An evolved xylose transporter from Zymomonas mobilis enhances sugar transport in Escherichia coli
    • Ren C., Chen T., Zhang J., Liang L., Lin Z. An evolved xylose transporter from Zymomonas mobilis enhances sugar transport in Escherichia coli. Microb. Cell Fact. 2009, 8:66.
    • (2009) Microb. Cell Fact. , vol.8 , pp. 66
    • Ren, C.1    Chen, T.2    Zhang, J.3    Liang, L.4    Lin, Z.5
  • 37
    • 77955660471 scopus 로고    scopus 로고
    • Identification and inactivation of pleiotropic regulator CcpA to eliminate glucose repression of xylose utilization in Clostridium acetobutylicum
    • Ren C., Gu Y., Hu S., Wu Y., Wang P., Yang Y., Yang C., Yang S., Jiang W. Identification and inactivation of pleiotropic regulator CcpA to eliminate glucose repression of xylose utilization in Clostridium acetobutylicum. Metab. Eng. 2010, 12:446-454.
    • (2010) Metab. Eng. , vol.12 , pp. 446-454
    • Ren, C.1    Gu, Y.2    Hu, S.3    Wu, Y.4    Wang, P.5    Yang, Y.6    Yang, C.7    Yang, S.8    Jiang, W.9
  • 38
    • 0026750940 scopus 로고
    • Catabolite repression of the xyl operon in Bacillus megaterium
    • Rygus T., Hillen W. Catabolite repression of the xyl operon in Bacillus megaterium. J. Bacteriol. 1992, 174:3049-3055.
    • (1992) J. Bacteriol. , vol.174 , pp. 3049-3055
    • Rygus, T.1    Hillen, W.2
  • 39
    • 33947192191 scopus 로고    scopus 로고
    • Xylose transport studies with xylose-utilizing Saccharomyces cerevisiae strains expressing heterologous and homologous permeases
    • Saloheimo A., Rauta J., Stasyk O.V., Sibirny A.A., Penttila M., Ruohonen L. Xylose transport studies with xylose-utilizing Saccharomyces cerevisiae strains expressing heterologous and homologous permeases. Appl. Microbiol. Biotechnol. 2007, 74:1041-1052.
    • (2007) Appl. Microbiol. Biotechnol. , vol.74 , pp. 1041-1052
    • Saloheimo, A.1    Rauta, J.2    Stasyk, O.V.3    Sibirny, A.A.4    Penttila, M.5    Ruohonen, L.6
  • 40
    • 0025774329 scopus 로고
    • Molecular cloning, structure, promoters and regulatory elements for transcription of the Bacillus licheniformis encoded regulon for xylose utilization
    • Scheler A., Rygus T., Allmansberger R., Hillen W. Molecular cloning, structure, promoters and regulatory elements for transcription of the Bacillus licheniformis encoded regulon for xylose utilization. Arch. Microbiol. 1991, 155:526-534.
    • (1991) Arch. Microbiol. , vol.155 , pp. 526-534
    • Scheler, A.1    Rygus, T.2    Allmansberger, R.3    Hillen, W.4
  • 41
    • 77955132053 scopus 로고    scopus 로고
    • AraC protein, regulation of the l-arabinose operon in Escherichia coli, and the light switch mechanism of AraC action
    • Schleif R. AraC protein, regulation of the l-arabinose operon in Escherichia coli, and the light switch mechanism of AraC action. FEMS Microbiol. Rev. 2010, 34:779-796.
    • (2010) FEMS Microbiol. Rev. , vol.34 , pp. 779-796
    • Schleif, R.1
  • 42
    • 0030030841 scopus 로고    scopus 로고
    • A Bacillus subtilis 168 mutant with increased xylose uptake can utilize xylose as sole carbon source
    • Schmiedel D., Hillen W. A Bacillus subtilis 168 mutant with increased xylose uptake can utilize xylose as sole carbon source. FEMS Microbiol. Lett. 1996, 135:175-178.
    • (1996) FEMS Microbiol. Lett. , vol.135 , pp. 175-178
    • Schmiedel, D.1    Hillen, W.2
  • 43
    • 78049506965 scopus 로고    scopus 로고
    • Transcriptional analysis of differential carbohydrate utilization by Clostridium acetobutylicum
    • Servinsky M.D., Kiel J.T., Dupuy N.F., Sund C.J. Transcriptional analysis of differential carbohydrate utilization by Clostridium acetobutylicum. Microbiology 2010, 156:3478-3491.
    • (2010) Microbiology , vol.156 , pp. 3478-3491
    • Servinsky, M.D.1    Kiel, J.T.2    Dupuy, N.F.3    Sund, C.J.4
  • 44
    • 36248966555 scopus 로고    scopus 로고
    • Targeted gene disruption by use of a group II intron (targetron) vector in Clostridium acetobutylicum
    • Shao L., Hu S., Yang Y., Gu Y., Chen J., Yang Y., Jiang W., Yang S. Targeted gene disruption by use of a group II intron (targetron) vector in Clostridium acetobutylicum. Cell Res. 2007, 17:963-965.
    • (2007) Cell Res. , vol.17 , pp. 963-965
    • Shao, L.1    Hu, S.2    Yang, Y.3    Gu, Y.4    Chen, J.5    Yang, Y.6    Jiang, W.7    Yang, S.8
  • 45
    • 0026697024 scopus 로고
    • Regulation of Staphylococcus xylosus xylose utilization genes at the molecular level
    • Sizemore C., Wieland B., Gotz F., Hillen W. Regulation of Staphylococcus xylosus xylose utilization genes at the molecular level. J. Bacteriol. 1992, 174:3042-3048.
    • (1992) J. Bacteriol. , vol.174 , pp. 3042-3048
    • Sizemore, C.1    Wieland, B.2    Gotz, F.3    Hillen, W.4
  • 47
    • 37449012593 scopus 로고    scopus 로고
    • Regulation of D-xylose metabolism in Caulobacter crescentus by a LacI-type repressor
    • Stephens C., Christen B., Watanabe K., Fuchs T., Jenal U. Regulation of D-xylose metabolism in Caulobacter crescentus by a LacI-type repressor. J. Bacteriol. 2007, 189:8828-8834.
    • (2007) J. Bacteriol. , vol.189 , pp. 8828-8834
    • Stephens, C.1    Christen, B.2    Watanabe, K.3    Fuchs, T.4    Jenal, U.5
  • 48
    • 0041527249 scopus 로고    scopus 로고
    • Overexpression of groESL in Clostridium acetobutylicum results in increased solvent production and tolerance, prolonged metabolism, and changes in the cell's transcriptional program
    • Tomas C.A., Welker N.E., Papoutsakis E.T. Overexpression of groESL in Clostridium acetobutylicum results in increased solvent production and tolerance, prolonged metabolism, and changes in the cell's transcriptional program. Appl. Environ. Microbiol. 2003, 69:4951-4965.
    • (2003) Appl. Environ. Microbiol. , vol.69 , pp. 4951-4965
    • Tomas, C.A.1    Welker, N.E.2    Papoutsakis, E.T.3
  • 49
    • 0032876348 scopus 로고    scopus 로고
    • Development and characterization of a gene expression reporter system for Clostridium acetobutylicum ATCC 824
    • Tummala S.B., Welker N.E., Papoutsakis E.T. Development and characterization of a gene expression reporter system for Clostridium acetobutylicum ATCC 824. Appl. Environ. Microbiol. 1999, 65:3793-3799.
    • (1999) Appl. Environ. Microbiol. , vol.65 , pp. 3793-3799
    • Tummala, S.B.1    Welker, N.E.2    Papoutsakis, E.T.3
  • 50
    • 0032425346 scopus 로고    scopus 로고
    • Sugar transporters from bacteria, parasites and mammals: structure-activity relationships
    • Walmsley A.R., Barrett M.P., Bringaud F., Gould G.W. Sugar transporters from bacteria, parasites and mammals: structure-activity relationships. Trends Biochem. Sci. 1998, 23:476-481.
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 476-481
    • Walmsley, A.R.1    Barrett, M.P.2    Bringaud, F.3    Gould, G.W.4
  • 51
    • 0000158375 scopus 로고
    • Thiolase from Clostridium acetobutylicum ATCC 824 and its role in the synthesis of acids and solvents
    • Wiesenborn D.P., Rudolph F.B., Papoutsakis E.T. Thiolase from Clostridium acetobutylicum ATCC 824 and its role in the synthesis of acids and solvents. Appl. Environ. Microbiol. 1988, 54:2717-2722.
    • (1988) Appl. Environ. Microbiol. , vol.54 , pp. 2717-2722
    • Wiesenborn, D.P.1    Rudolph, F.B.2    Papoutsakis, E.T.3
  • 52
    • 83055184898 scopus 로고    scopus 로고
    • Confirmation and elimination of xylose metabolism bottlenecks in glucose phosphoenolpyruvate-dependent phosphotransferase system-deficient Clostridium acetobutylicum for simultaneous utilization of glucose, xylose, and arabinose
    • Xiao H., Gu Y., Ning Y., Yang Y., Mitchell W.J., Jiang W., Yang S. Confirmation and elimination of xylose metabolism bottlenecks in glucose phosphoenolpyruvate-dependent phosphotransferase system-deficient Clostridium acetobutylicum for simultaneous utilization of glucose, xylose, and arabinose. Appl. Environ. Microbiol. 2011, 77:7886-7895.
    • (2011) Appl. Environ. Microbiol. , vol.77 , pp. 7886-7895
    • Xiao, H.1    Gu, Y.2    Ning, Y.3    Yang, Y.4    Mitchell, W.J.5    Jiang, W.6    Yang, S.7
  • 53
    • 79958709458 scopus 로고    scopus 로고
    • Metabolic engineering of Clostridium tyrobutyricum for n-butanol production
    • Yu M., Zhang Y., Tang I.C., Yang S.T. Metabolic engineering of Clostridium tyrobutyricum for n-butanol production. Metab. Eng. 2011, 13:373-382.
    • (2011) Metab. Eng. , vol.13 , pp. 373-382
    • Yu, M.1    Zhang, Y.2    Tang, I.C.3    Yang, S.T.4
  • 54
    • 84863265097 scopus 로고    scopus 로고
    • Ribulokinase and transcriptional regulation of arabinose metabolism in Clostridium acetobutylicum
    • Zhang L., Leyn S.A., Gu Y., Jiang W., Rodionov D.A., Yang C. Ribulokinase and transcriptional regulation of arabinose metabolism in Clostridium acetobutylicum. J Bacteriol. 2012, 194:1055-1064.
    • (2012) J Bacteriol. , vol.194 , pp. 1055-1064
    • Zhang, L.1    Leyn, S.A.2    Gu, Y.3    Jiang, W.4    Rodionov, D.A.5    Yang, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.