DNase activation by hypoxia-acidosis parallels but is independent of programmed cell death

Life Sciences

Volumn 91, Issue 7-8, 2012, Pages 223-229

  Thompson, John W ^a   Graham, Regina M ^a   Webster, Keith A ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis inducing factor; Bnip3; Calpains; Cardiac myocyte; DNase II; Hypoxia; Ischemia; Mitochondrial fission

Indexed keywords

APOPTOSIS INDUCING FACTOR; CALPAIN; CASPASE ACTIVATED DEOXYRIBONUCLEASE; CYSTEINE PROTEINASE INHIBITOR; DEOXYRIBONUCLEASE II; PROTEIN BNIP3; SINGLE STRANDED DNA; TRANSACTIVATOR PROTEIN;

ACIDOSIS; AEROBIC METABOLISM; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL HYPOXIA; CELL NUCLEUS; CELL PH; CONTROLLED STUDY; CYTOPLASM; DNA FRAGMENTATION; ENZYME ACTIVATION; IMMUNOCYTOCHEMISTRY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; RAT; WESTERN BLOTTING;

ACIDOSIS; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BLOTTING, WESTERN; CELL HYPOXIA; CELL NUCLEUS; CELLS, CULTURED; ENDODEOXYRIBONUCLEASES; ENZYME ACTIVATION; IMMUNOHISTOCHEMISTRY; MYOCARDIUM; PROTEIN TRANSPORT; RATS;

RATTUS;

EID: 84865600936     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.03.034     Document Type: Article

References (23)

1. M.A. Barry, and A. Eastman Identification of deoxyribonuclease II as an endonuclease involved in apoptosis Arch Biochem Biophys 300 1 1993 440 450 (Pubitemid 23225769)
2. C. Brooks, G. Cho, C.Y. Wang, T. Yang, and Z. Dong Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis Am J Physiol Cell Physiol 300 3 2011 C447 C455
3. L.M. Buja Myocardial ischemia and reperfusion injury Cardiovasc Pathol 14 4 2005 170 175 (Pubitemid 40977859)
4. M. Ferrand-Drake, C. Zhu, G. Gidö, A.J. Hansen, J.O. Karlsson, and B.A. Bahr Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c and caspase-3 activation in neurons exposed to transient hypoglycemia J Neurochem 85 6 2003 1431 1442 (Pubitemid 36702556)
5. D.P. Frazier, A. Wilson, R.M. Graham, J.W. Thompson, N.H. Bishopric, and K.A. Webster Acidosis regulates the stability, hydrophobicity and activity of the BH3-only protein Bnip3 Antioxid Redox Signal 8 9-10 2006 1625 1634 (Pubitemid 44726337)
6. R.M. Graham, J.W. Thompson, J. Wei, N.H. Bishopric, and K.A. Webster Regulation of Bnip3 death pathways by calcium, phosphorylation, and hypoxia-reoxygenation Antioxid Redox Signal 9 9 2007 1309 1315 (Pubitemid 47255010)
7. A. Hamacher-Brady, N.R. Brady, S.E. Logue, M.R. Sayen, M. Jinno, and L.A. Kirshenbaum Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy Cell Death Differ 14 1 2006 146 157
8. S. Hoffstein, G. Weissmann, and A.C. Fox Lysosomes in myocardial infarction: studies by means of cytochemistry and subcellular fractionation, with observations on the effects of methylprednisolone Circulation 53 3 Suppl. 1976 I34 I40
9. K. Ichihara, T. Haneda, S. Onodera, and Y. Abiko Inhibition of ischemia-induced subcellular redistribution of lysosomal enzymes in the perfused rat heart by the calcium entry blocker, diltiazem J Pharmacol Exp Ther 242 3 1987 1109 1113 (Pubitemid 17156559)
10. L.A. Kubasiak, O.M. Hernandez, N.H. Bishopric, and K.A. Webster Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3 Proc Natl Acad Sci U S A 99 20 2002 12825 12830
11. J. Li, J. Zhou, Y. Li, D. Qin, and P. Li Mitochondrial fission controls DNA fragmentation by regulating endonuclease G Free Radic Biol Med 49 4 2010 622 631
12. H.R. Lohr, K. Kuntchithapautham, A.K. Sharma, and B. Roher Multiple, parallel cellular suicide mechanisms participate in photoreceptor cell death Exp Eye Res 83 2 2006 380 389 (Pubitemid 43850954)
13. H. Otera, S. Ohsakaya, Z. Nagaura, N. Ishihara, and K. Mihara Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space EMBO J 24 7 2005 1375 1386 (Pubitemid 40593058)
14. C. Steenbergen, M.E. Perlman, R.E. London, and E. Murphy Mechanism of preconditioning. Ionic alterations Circ Res 72 1 1993 112 125
15. T. Tsukada, M. Watanabe, and T. Yamashima Implications of CAD and DNase II in ischemic neuronal necrosis specific for the primate hippocampus J Neurochem 79 6 2001 1196 1206 (Pubitemid 34019797)
16. C. Vande Velde, J. Cizeau, D. Dubik, J. Alimonti, T. Brown, and S. Israels BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore Mol Cell Biol 20 15 2000 5454 5468 (Pubitemid 30482883)
17. C. Vindis, M. Elbaz, I. Escargueil-Blanc, N. Augé, A. Heniquez, and J.C. Thiers Two distinct calcium-dependent mitochondrial pathways are involved in oxidized LDL-induced apoptosis Arterioscler Thromb Vasc Biol 25 3 2005 639 645 [Mar] (Pubitemid 40315691)
18. K.A. Webster, D.J. Discher, S. Kaiser, O. Hernandez, B. Sato, and N.H. Bishopric Hypoxia-activated apoptosis of cardiac myocytes requires reoxygenation or a pH shift and is independent of p53 J Clin Invest 104 3 1999 239 252
19. K.A. Webster, R.M. Graham, J.W. Thompson, M.G. Spiga, D.P. Frazier, and A. Wilson Redox stress and the contributions of BH3-only proteins to infarction Antioxid Redox Signal 9-10 2006 1667 1676 (Pubitemid 44726340)
20. T. Yamashima, T.C. Saido, M. Takita, A. Miyazawa, J. Yamano, and A. Miyakawa Transient brain ischemia provokes Ca2+, PIP2, and calpain responses prior to delayed neuronal death in monkeys Eur J Neurosci 8 1996 1932 1944
21. S.W. Yu, Y. Wang, D.S. Frydenlund, O.P. Ottersen, V.L. Dawson, and T.M. Dawson Outer mitochondrial membrane localization of apoptosis-inducing factor: mechanistic implications for release ASN Neuro 1 5 2009 e00021 [pii:]
22. J. Zhang, J. Ye, A. Altafaj, M. Cardona, N. Bahi, and M. Llovera EndoG links Bnip3-induced mitochondrial damage and caspase-independent DNA fragmentation in ischemic cardiomyocytes PLoS One 6 3 2011 e17998
23. Z. Zhang, X. Yang, S. Zhang, X. Ma, and J. Kong BNIP3 upregulation and EndoG translocation in delayed neuronal death in stroke and in hypoxia Stroke 38 5 2007 1606 1613 (Pubitemid 46684181)