메뉴 건너뛰기




Volumn 25, Issue 3, 2012, Pages 149-153

Glycemic variability: Looking beyond the A1C

Author keywords

[No Author keywords available]

Indexed keywords

ACARBOSE; CALCIUM; GLIBENCLAMIDE; GLUCOSE; HEMOGLOBIN A1C; INSULIN; REPAGLINIDE;

EID: 84865596787     PISSN: 10409165     EISSN: 19447353     Source Type: Journal    
DOI: 10.2337/diaspect.25.3.149     Document Type: Article
Times cited : (18)

References (41)
  • 2
    • 77953071526 scopus 로고    scopus 로고
    • Arguments for and against the role of glucose variability in the development of diabetes complications
    • Kilpatrick ES: Arguments for and against the role of glucose variability in the development of diabetes complications. J Diabetes Sci Technol 3:649-655, 2009
    • (2009) J Diabetes Sci Technol , vol.3 , pp. 649-655
    • Kilpatrick, E.S.1
  • 3
    • 77954789710 scopus 로고    scopus 로고
    • For debate: Glucose variability and diabetes complication risk: We need to know the answer
    • Kilpatrick ES, Rigby AS, Atkin SL: For debate: glucose variability and diabetes complication risk: we need to know the answer. Diabet Med 27:868-871, 2010
    • (2010) Diabet Med , vol.27 , pp. 868-871
    • Kilpatrick, E.S.1    Rigby, A.S.2    Atkin, S.L.3
  • 4
    • 77953637843 scopus 로고    scopus 로고
    • Glycaemic variability and complications in patients with diabetes mellitus: Evidence from a systematic review of the literature
    • Nalysnyk L, Hernandez-Medina M, Krishnarajah G: Glycaemic variability and complications in patients with diabetes mellitus: evidence from a systematic review of the literature. Diabetes Obes Metab 12:288-298, 2010
    • (2010) Diabetes Obes Metab , vol.12 , pp. 288-298
    • Nalysnyk, L.1    Hernandez-Medina, M.2    Krishnarajah, G.3
  • 5
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • DCCT Research Group
    • DCCT Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329:977-986, 1993
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 6
    • 0029094533 scopus 로고
    • 1c) to the risk of development and progression of retinopathy in the Diabetes Control and Complications Trial
    • DCCT Research Group
    • 1c) to the risk of development and progression of retinopathy in the Diabetes Control and Complications Trial. Diabetes 44:968-983, 1995
    • (1995) Diabetes , vol.44 , pp. 968-983
  • 7
    • 42449121829 scopus 로고    scopus 로고
    • Effect of glycemic exposure on the risk of microvascular complications in the Diabetes Control and Complications Trial - Revisited
    • Group DER
    • Lachin JM, Genuth S, Nathan DM, Zinman B, Rutledge BN, Group DER: Effect of glycemic exposure on the risk of microvascular complications in the Diabetes Control and Complications Trial - revisited. Diabetes 57:995-1001, 2008
    • (2008) Diabetes , vol.57 , pp. 995-1001
    • Lachin, J.M.1    Genuth, S.2    Nathan, D.M.3    Zinman, B.4    Rutledge, B.N.5
  • 8
    • 77954804860 scopus 로고    scopus 로고
    • Glycemic variability: The third component of the dysglycemia in diabetes. Is it important? How to measure it?
    • Monnier L, Colette C, Owens DR: Glycemic variability: the third component of the dysglycemia in diabetes. Is it important? How to measure it? J Diabetes Sci Technol 2:1094-1100, 2008
    • (2008) J Diabetes Sci Technol , vol.2 , pp. 1094-1100
    • Monnier, L.1    Colette, C.2    Owens, D.R.3
  • 9
    • 80055050523 scopus 로고    scopus 로고
    • Glycemic variability: Measurement and utility in clinical medicine and research - One viewpoint
    • Rodbard D: Glycemic variability: measurement and utility in clinical medicine and research - one viewpoint. Diabetes Technol Ther 13:1077-1080, 2011
    • (2011) Diabetes Technol Ther , vol.13 , pp. 1077-1080
    • Rodbard, D.1
  • 10
    • 64149096637 scopus 로고    scopus 로고
    • Rapid 'glycaemic swings' induce nitrosative stress, activate poly(ADP-ribose) polymerase and impair endothelial function in a rat model of diabetes mellitus
    • Horvath EM, Benko R, Kiss L, Muranyi M, Pek T, Fekete K, Barany T, Somlai A, Csordas A, Szabo C: Rapid 'glycaemic swings' induce nitrosative stress, activate poly(ADP-ribose) polymerase and impair endothelial function in a rat model of diabetes mellitus. Diabetologia 52:952-961, 2009
    • (2009) Diabetologia , vol.52 , pp. 952-961
    • Horvath, E.M.1    Benko, R.2    Kiss, L.3    Muranyi, M.4    Pek, T.5    Fekete, K.6    Barany, T.7    Somlai, A.8    Csordas, A.9    Szabo, C.10
  • 11
    • 33645745733 scopus 로고    scopus 로고
    • Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes
    • Monnier L, Mas E, Ginet C, Michel F, Villon L, Cristol JP, Colette C: Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA 295:1681-1687, 2006
    • (2006) JAMA , vol.295 , pp. 1681-1687
    • Monnier, L.1    Mas, E.2    Ginet, C.3    Michel, F.4    Villon, L.5    Cristol, J.P.6    Colette, C.7
  • 12
    • 48449098502 scopus 로고    scopus 로고
    • Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients
    • Ceriello A, Esposito K, Piconi L, Ihnat MA, Thorpe JE, Testa R, Boemi M, Giugliano D: Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients. Diabetes 57:1349-1354, 2008
    • (2008) Diabetes , vol.57 , pp. 1349-1354
    • Ceriello, A.1    Esposito, K.2    Piconi, L.3    Ihnat, M.A.4    Thorpe, J.E.5    Testa, R.6    Boemi, M.7    Giugliano, D.8
  • 13
    • 36649006065 scopus 로고    scopus 로고
    • Glucose fluctuations and activation of oxidative stress in patients with type 1 diabetes
    • DOI 10.1007/s00125-007-0842-6
    • Wentholt IM, Kulik W, Michels RP, Hoekstra JB, DeVries JH: Glucose fluctuations and activation of oxidative stress in patients with type 1 diabetes. Diabetologia 51:183-190, 2008 (Pubitemid 50002199)
    • (2008) Diabetologia , vol.51 , Issue.1 , pp. 183-190
    • Wentholt, I.M.E.1    Kulik, W.2    Michels, R.P.J.3    Hoekstra, J.B.L.4    DeVries, J.H.5
  • 14
    • 33746460818 scopus 로고    scopus 로고
    • The effect of glucose variability on the risk of microvascular complications in type 1 diabetes
    • DOI 10.2337/dc06-0293
    • Kilpatrick ES, Rigby AS, Atkin SL: The effect of glucose variability on the risk of microvascular complications in type 1 diabetes. Diabetes Care 29:1486-1490, 2006 (Pubitemid 44127568)
    • (2006) Diabetes Care , vol.29 , Issue.7 , pp. 1486-1490
    • Kilpatrick, E.S.1    Rigby, A.S.2    Atkin, S.L.3
  • 15
    • 0034771456 scopus 로고    scopus 로고
    • The relation of glycaemia to the risk of development and progression of retinopathy in the Diabetic Control and Complications Trial
    • DOI 10.1007/s001250100635
    • Service FJ, O'Brien PC: The relation of glycaemia to the risk of development and progression of retinopathy in the Diabetic Control and Complications Trial. Diabetologia 44:1215-1220, 2001 (Pubitemid 33010497)
    • (2001) Diabetologia , vol.44 , Issue.10 , pp. 1215-1220
    • Service, F.J.1    O'Brien, P.C.2
  • 16
    • 70349653641 scopus 로고    scopus 로고
    • Effect of glucose variability on the long-term risk of microvascular complications in type 1 diabetes
    • Kilpatrick ES, Rigby AS, Atkin SL: Effect of glucose variability on the long-term risk of microvascular complications in type 1 diabetes. Diabetes Care 32:1901-1903, 2009
    • (2009) Diabetes Care , vol.32 , pp. 1901-1903
    • Kilpatrick, E.S.1    Rigby, A.S.2    Atkin, S.L.3
  • 17
    • 58849150951 scopus 로고    scopus 로고
    • A1C variability and the risk of microvascular complications in type 1 diabetes: Data from the Diabetes Control and Complications Trial
    • Kilpatrick ES, Rigby AS, Atkin SL: A1C variability and the risk of microvascular complications in type 1 diabetes: data from the Diabetes Control and Complications Trial. Diabetes Care 31:2198-2202, 2008
    • (2008) Diabetes Care , vol.31 , pp. 2198-2202
    • Kilpatrick, E.S.1    Rigby, A.S.2    Atkin, S.L.3
  • 18
    • 69949164144 scopus 로고    scopus 로고
    • Glucose variability does not contribute to the development of peripheral and autonomic neuropathy in type 1 diabetes: Data from the DCCT
    • Siegelaar SE, Kilpatrick ES, Rigby AS, Atkin SL, Hoekstra JB, Devries JH: Glucose variability does not contribute to the development of peripheral and autonomic neuropathy in type 1 diabetes: data from the DCCT. Diabetologia 52:2229-2232, 2009
    • (2009) Diabetologia , vol.52 , pp. 2229-2232
    • Siegelaar, S.E.1    Kilpatrick, E.S.2    Rigby, A.S.3    Atkin, S.L.4    Hoekstra, J.B.5    Devries, J.H.6
  • 19
    • 0036400364 scopus 로고    scopus 로고
    • The relationship between blood glucose excursions and painful diabetic peripheral neuropathy: A pilot study
    • DOI 10.1046/j.1464-5491.2002.00801.x
    • Oyibo SO, Prasad YD, Jackson NJ, Jude EB, Boulton AJ: The relationship between blood glucose excursions and painful diabetic peripheral neuropathy: a pilot study. Diabet Med 19:870-873, 2002 (Pubitemid 35177190)
    • (2002) Diabetic Medicine , vol.19 , Issue.10 , pp. 870-873
    • Oyibo, S.O.1    Prasad, Y.D.M.2    Jackson, N.J.3    Jude, E.B.4    Boulton, A.J.M.5
  • 20
    • 57049128707 scopus 로고    scopus 로고
    • Can glycaemic variability, as calculated from blood glucose self-monitoring, predict the development of complications in type 1 diabetes over a decade?
    • Bragd J, Adamson U, Backlund LB, Lins PE, Moberg E, Oskarsson P: Can glycaemic variability, as calculated from blood glucose self-monitoring, predict the development of complications in type 1 diabetes over a decade? Diabetes Metab 34:612-616, 2008
    • (2008) Diabetes Metab , vol.34 , pp. 612-616
    • Bragd, J.1    Adamson, U.2    Backlund, L.B.3    Lins, P.E.4    Moberg, E.5    Oskarsson, P.6
  • 21
    • 37549005949 scopus 로고    scopus 로고
    • 1c in the prediction of cardiovascular disease in patients with type 1 diabetes
    • 1c in the prediction of cardiovascular disease in patients with type 1 diabetes. Diabetologia 51:365-371, 2008
    • (2008) Diabetologia , vol.51 , pp. 365-371
    • Kilpatrick, E.S.1    Rigby, A.S.2    Atkin, S.L.3
  • 23
    • 79953064502 scopus 로고    scopus 로고
    • Glycaemic variability is associated with coronary artery calcium in men with type 1 diabetes: The Coronary Artery Calcification in Type 1 Diabetes study
    • Snell-Bergeon JK, Roman R, Rodbard D, Garg S, Maahs DM, Schauer IE, Bergman BC, Kinney GL, Rewers M: Glycaemic variability is associated with coronary artery calcium in men with type 1 diabetes: the Coronary Artery Calcification in Type 1 Diabetes study. Diabet Med 27:1436-1442, 2010
    • (2010) Diabet Med , vol.27 , pp. 1436-1442
    • Snell-Bergeon, J.K.1    Roman, R.2    Rodbard, D.3    Garg, S.4    Maahs, D.M.5    Schauer, I.E.6    Bergman, B.C.7    Kinney, G.L.8    Rewers, M.9
  • 24
    • 79951941643 scopus 로고    scopus 로고
    • Association of glycemic variability and the presence and severity of coronary artery disease in patients with type 2 diabetes
    • [article online]. Available from
    • Su G, Mi S, Tao H, Li Z, Yang H, Zheng H, Zhou Y, Ma C: Association of glycemic variability and the presence and severity of coronary artery disease in patients with type 2 diabetes [article online]. Cardiovasc Diabetol 10:19, 2011. Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056765/?tool= pubmed
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 19
    • Su, G.1    Mi, S.2    Tao, H.3    Li, Z.4    Yang, H.5    Zheng, H.6    Zhou, Y.7    Ma, C.8
  • 26
    • 33644832167 scopus 로고    scopus 로고
    • Postprandial blood glucose is a stronger predictor of cardiovascular events than fasting blood glucose in type 2 diabetes mellitus, particularly in women: Lessons from the San Luigi Gonzaga diabetes study
    • DOI 10.1210/jc.2005-1005
    • Cavalot F, Petrelli A, Traversa M, Bonomo K, Fiora E, Conti M, Anfossi G, Costa G, Trovati M: Postprandial blood glucose is a stronger predictor of cardiovascular events than fasting blood glucose in type 2 diabetes mellitus, particularly in women: lessons from the San Luigi Gonzaga Diabetes Study. J Clin Endocrinol Metab 91:813-819, 2006 (Pubitemid 43357744)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.3 , pp. 813-819
    • Cavalot, F.1    Petrelli, A.2    Traversa, M.3    Bonomo, K.4    Fiora, E.5    Conti, M.6    Anfossi, G.7    Costa, G.8    Trovati, M.9
  • 27
    • 0029015145 scopus 로고
    • Long-term instability of fasting plasma glucose predicts mortality in elderly NIDDM patients: The Verona Diabetes Study
    • Muggeo M, Verlato G, Bonora E, Ciani F, Moghetti P, Eastman R, Crepaldi G, de Marco R: Long-term instability of fasting plasma glucose predicts mortality in elderly NIDDM patients: the Verona Diabetes Study. Diabetologia 38:672-679, 1995
    • (1995) Diabetologia , vol.38 , pp. 672-679
    • Muggeo, M.1    Verlato, G.2    Bonora, E.3    Ciani, F.4    Moghetti, P.5    Eastman, R.6    Crepaldi, G.7    De Marco, R.8
  • 28
    • 0030866140 scopus 로고    scopus 로고
    • Long-term instability of fasting plasma glucose, a novel predictor of cardiovascular mortality in elderly patients with non-insulin-dependent diabetes mellitus: The verona diabetes study
    • Muggeo M, Verlato G, Bonora E, Zoppini G, Corbellini M, de Marco R: Long-term instability of fasting plasma glucose, a novel predictor of cardiovascular mortality in elderly patients with non-insulin-dependent diabetes mellitus: the Verona Diabetes Study. Circulation 96:1750-1754, 1997 (Pubitemid 27400729)
    • (1997) Circulation , vol.96 , Issue.6 , pp. 1750-1754
    • Muggeo, M.1    Verlato, G.2    Bonora, E.3    Zoppini, G.4    Corbellini, M.5    De Marco, R.6
  • 29
    • 0033957393 scopus 로고    scopus 로고
    • Fasting plasma glucose variability predicts 10-year survival of type 2 diabetic patients: The Verona Diabetes Study
    • Muggeo M, Zoppini G, Bonora E, Brun E, Bonadonna RC, Moghetti P, Verlato G: Fasting plasma glucose variability predicts 10-year survival of type 2 diabetic patients: the Verona Diabetes Study. Diabetes Care 23:45-50, 2000 (Pubitemid 30022893)
    • (2000) Diabetes Care , vol.23 , Issue.1 , pp. 45-50
    • Muggeo, M.1    Zoppini, G.2    Bonora, E.3    Brun, E.4    Bonadonna, R.C.5    Moghetti, P.6    Verlato, G.7
  • 31
    • 77955423064 scopus 로고    scopus 로고
    • The effect of fasting plasma glucose variability on the risk of retinopathy in type 2 diabetic patients: Retrospective long-term follow-up
    • Takao T, Ide T, Yanagisawa H, Kikuchi M, Kawazu S, Matsuyama Y: The effect of fasting plasma glucose variability on the risk of retinopathy in type 2 diabetic patients: retrospective long-term follow-up. Diabetes Res Clin Pract 89:296-302, 2010
    • (2010) Diabetes Res Clin Pract , vol.89 , pp. 296-302
    • Takao, T.1    Ide, T.2    Yanagisawa, H.3    Kikuchi, M.4    Kawazu, S.5    Matsuyama, Y.6
  • 32
    • 79952042507 scopus 로고    scopus 로고
    • The effects of fasting plasma glucose variability and timedependent glycemic control on the long-term risk of retinopathy in type 2 diabetic patients
    • Takao T, Ide T, Yanagisawa H, Kikuchi M, Kawazu S, Matsuyama Y: The effects of fasting plasma glucose variability and timedependent glycemic control on the long-term risk of retinopathy in type 2 diabetic patients. Diabetes Res Clin Pract 91:e40-e42, 2011
    • (2011) Diabetes Res Clin Pract , vol.91
    • Takao, T.1    Ide, T.2    Yanagisawa, H.3    Kikuchi, M.4    Kawazu, S.5    Matsuyama, Y.6
  • 34
    • 0346727578 scopus 로고    scopus 로고
    • Acarbose reduces the risk for myocardial infarction in type 2 diabetic patients: Meta-analysis of seven long-term studies
    • DOI 10.1016/S0195-668X(03)00468-8
    • Hanefeld M, Cagatay M, Petrowitsch T, Neuser D, Petzinna D, Rupp M: Acarbose reduces the risk for myocardial infarction in type 2 diabetic patients: meta-analysis of seven long-term studies. Eur Heart J 25:10-16, 2004 (Pubitemid 38055587)
    • (2004) European Heart Journal , vol.25 , Issue.1 , pp. 10-16
    • Hanefeld, M.1    Cagatay, M.2    Petrowitsch, T.3    Neuser, D.4    Petzinna, D.5    Rupp, M.6
  • 35
    • 3142760075 scopus 로고    scopus 로고
    • Regression of carotid atherosclerosis by control of postprandial hyperglycemia in type 2 diabetes mellitus
    • DOI 10.1161/01.CIR.0000134501.57864.66
    • Esposito K, Giugliano D, Nappo F, Marfella R; Campanian Postprandial Hyperglycemia Study Group: Regression of carotid atherosclerosis by control of postprandial hyperglycemia in type 2 diabetes mellitus. Circulation 110:214-219, 2004 (Pubitemid 38924590)
    • (2004) Circulation , vol.110 , Issue.2 , pp. 214-219
    • Esposito, K.1    Giugliano, D.2    Nappo, F.3    Marfella, R.4
  • 37
    • 34147095432 scopus 로고    scopus 로고
    • Association of glucose levels and glucose variability with mood in type 1 diabetic patients
    • DOI 10.1007/s00125-007-0643-y
    • Hermanns N, Scheff C, Kulzer B, Weyers P, Pauli P, Kubiak T, Haak T: Association of glucose levels and glucose variability with mood in type 1 diabetic patients. Diabetologia 50:930-933, 2007 (Pubitemid 46559266)
    • (2007) Diabetologia , vol.50 , Issue.5 , pp. 930-933
    • Hermanns, N.1    Scheff, C.2    Kulzer, B.3    Weyers, P.4    Pauli, P.5    Kubiak, T.6    Haak, T.7
  • 38
    • 34547693377 scopus 로고    scopus 로고
    • Effects of blood glucose rate of changes on perceived mood and cognitive symptoms in insulin-treated type 2 diabetes
    • DOI 10.2337/dc06-2480
    • Cox DJ, McCall A, Kovatchev B, Sarwat S, Ilag LL, Tan MH: Effects of blood glucose rate of changes on perceived mood and cognitive symptoms in insulin-treated type 2 diabetes. Diabetes Care 30:2001-2002, 2007 (Pubitemid 47219408)
    • (2007) Diabetes Care , vol.30 , Issue.8 , pp. 2001-2002
    • Cox, D.J.1    McCall, A.2    Kovatchev, B.3    Sarwat, S.4    Ilag, L.L.5    Tan, M.H.6
  • 39
    • 70349952543 scopus 로고    scopus 로고
    • Fasting plasma glucose variability as a marker of nocturnal hypoglycemia in diabetes: Evidence from the PREDICTIVE study
    • Niskanen L, Virkamaki A, Hansen JB, Saukkonen T: Fasting plasma glucose variability as a marker of nocturnal hypoglycemia in diabetes: evidence from the PREDICTIVE study. Diabetes Res Clin Pract 86:e15-e18, 2009
    • (2009) Diabetes Res Clin Pract , vol.86
    • Niskanen, L.1    Virkamaki, A.2    Hansen, J.B.3    Saukkonen, T.4
  • 40
    • 35848934997 scopus 로고    scopus 로고
    • Relating mean blood glucose and glucose variability to the risk of multiple episodes of hypoglycaemia in type 1 diabetes
    • DOI 10.1007/s00125-007-0820-z
    • Kilpatrick ES, Rigby AS, Goode K, Atkin SL: Relating mean blood glucose and glucose variability to the risk of multiple episodes of hypoglycaemia in type 1 diabetes. Diabetologia 50:2553-2561, 2007 (Pubitemid 350060641)
    • (2007) Diabetologia , vol.50 , Issue.12 , pp. 2553-2561
    • Kilpatrick, E.S.1    Rigby, A.S.2    Goode, K.3    Atkin, S.L.4
  • 41
    • 79960403329 scopus 로고    scopus 로고
    • The contribution of glucose variability to asymptomatic hypoglycemia in persons with type 2 diabetes
    • Monnier L, Wojtusciszyn A, Colette C, Owens D: The contribution of glucose variability to asymptomatic hypoglycemia in persons with type 2 diabetes. Diabetes Technol Ther 13:813-818, 2011
    • (2011) Diabetes Technol Ther , vol.13 , pp. 813-818
    • Monnier, L.1    Wojtusciszyn, A.2    Colette, C.3    Owens, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.