Development of monoclonal antibody-based immunoassays for detection of Helicobacter pylori neutrophil-activating protein

Journal of Immunological Methods

Volumn 384, Issue 1-2, 2012, Pages 1-9

  Iankov, Ianko D ^a   Penheiter, Alan R ^a   Carlson, Stephanie K ^a   Galanis, Evanthia ^a  

^a MAYO CLINIC   (United States)

Author keywords

Helicobacter pylori; Immunoassays; Monoclonal antibody; NAP

Indexed keywords

ANTIGEN; EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 16F4; MONOCLONAL ANTIBODY 23 C8; MONOCLONAL ANTIBODY NAP; NEUTROPHIL ACTIVATING PROTEIN; NEUTROPHIL ACTIVATING PROTEIN ANTIGEN; PEPTIDE; RECOMBINANT ANTIGEN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIRUS VECTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; BACTERIAL STRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; FEMALE; HELICOBACTER PYLORI; IMMUNIZATION; IMMUNOASSAY; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; INDIRECT IMMUNOFLUORESCENCE TEST; MEASLES VIRUS; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; SERODIAGNOSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CERCOPITHECUS AETHIOPS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; EPITOPES; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GREEN FLUORESCENT PROTEINS; HELICOBACTER PYLORI; IMMUNOBLOTTING; MICE; MICE, INBRED BALB C; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; VERO CELLS;

HELICOBACTER; HELICOBACTER PYLORI; MEASLES VIRUS; MUS; REPLICATION COMPETENT VIRUSES;

EID: 84865592602     PISSN: 00221759     EISSN: 18727905     Source Type: Journal    
DOI: 10.1016/j.jim.2012.06.010     Document Type: Article

References (36)

1. Adachi K., Kawamura A., Ono M., Masuzaki K., Takashima T., Yuki M., Fujishiro H., Ishihara S., Kinoshita Y. Comparative evaluation of urine-based and other minimally invasive methods for the diagnosis of Helicobacter pylori infection. J. Gastroenterol. 2002, 37:703.
2. Amedei A., Cappon A., Codolo G., Cabrelle A., Polenghi A., Benagiano M., Tasca E., Azzurri A., D'Elios M.M., Del Prete G., de Bernard M. The neutrophil-activating protein of Helicobacter pylori promotes Th1 immune responses. J. Clin. Invest. 2006, 116:1092.
3. Amedei A., Codolo G., Del Prete G., de Bernard M., D'Elios M.M. The effect of Helicobacter pylori on asthma and allergy. J. Asthma Allergy 2010, 3:139.
4. Campbell A.M. Monoclonal antibody and immunosensor technology. Laboratory Techniques in Biochemistry and Molecular Biology 1991, vol. 23. Elsevier, Amsterdam.
5. Cirak M.Y., Akyön Y., Mégraud F. Diagnosis of Helicobacter pylori. Helicobacter 2007, 12(Suppl. 1):4.
6. Codolo G., Mazzi P., Amedei A., Del Prete G., Berton G., D'Elios M.M., de Bernard M. The neutrophil-activating protein of Helicobacter pylori down-modulates Th2 inflammation in ovalbumin-induced allergic asthma. Cell. Microbiol. 2008, 10:2355.
7. Codolo G., Fassan M., Munari F., Volpe A., Bassi P., Rugge M., Pagano F., D'Elios M.M., de Bernard M. HP-NAP inhibits the growth of bladder cancer in mice by activating a cytotoxic Th1 response. Cancer Immunol. Immunother. 2012, 61:31.
8. Del Giudice G., Covacci A., Telford J.L., Montecucco C., Rappuoli R. The design of vaccines against Helicobacter pylori and their development. Annu. Rev. Immunol. 2001, 19:523.
9. Del Prete G., Chiumiento L., Amedei A., Piazza M., D'Elios M.M., Codolo G., de Bernard M., Masetti M., Bruschi F. Immunosuppression of TH2 responses in Trichinella spiralis infection by Helicobacter pylori neutrophil-activating protein. J. Allergy Clin. Immunol. 2008, 122:908.
10. D'Elios M.M., Andersen L.P. Helicobacter pylori inflammation, immunity, and vaccines. Helicobacter 2007, 12(Suppl. 1):15.
11. D'Elios M.M., Montecucco C., de Bernard M. VacA and HP-NAP, Ying and Yang of Helicobacter pylori-associated gastric inflammation. Clin. Chim. Acta 2007, 381:32.
12. D'Elios M.M., Amedei A., Cappon A., Del Prete G., de Bernard M. The neutrophil-activating protein of Helicobacter pylori (HP-NAP) as an immune modulating agent. FEMS Immunol. Med. Microbiol. 2007, 50:157.
13. Duprex W.P., McQuaid S., Hangartner L., Billeter M.A., Rima B.K. Observation of measles virus cell-to-cell spread in astrocytoma cells by using a green fluorescent protein-expressing recombinant virus. J. Virol. 1999, 73:9568.
14. Duprex W.P., McQuaid S., Roscic-Mrkic B., Cattaneo R., McCallister C., Rima B.K. In vitro and in vivo infection of neural cells by a recombinant measles virus expressing enhanced green fluorescent protein. J. Virol. 2000, 74:7972.
15. Evans D.J., Evans D.G., Takemura T., Nakano H., Lampert H.C., Graham D.Y., Granger D.N., Kvietys P.R. Characterization of a Helicobacter pylori neutrophil-activating protein. Infect. Immun. 1995, 63:2213.
16. Guarner J., Kalach N., Elitsur Y., Koletzko S. Helicobacter pylori diagnostic tests in children: review of the literature from 1999 to 2009. Eur. J. Pediatr. 2010, 169:15.
17. Hino B., Eliakim R., Levine A., Sprecher H., Berkowitz D., Hartman C., Eshach-Adiv O., Shamir R. Comparison of invasive and non-invasive tests diagnosis and monitoring of Helicobacter pylori infection in children. J. Pediatr. Gastroenterol. Nutr. 2004, 39:519.
18. 13C-urea breath test for the primary diagnosis of Helicobacter pylori infection and monitoring treatment outcome. Eur. J. Gastroenterol. Hepatol. 2006, 18:595.
19. Iankov I.D., Haralambieva I.H., Galanis E. Immunogenicity of attenuated measles virus engineered to express Helicobacter pylori neutrophil-activating protein. Vaccine 2011, 29:1710.
20. Khalifa M.M., Sharaf R.R., Aziz R.K. Helicobacter pylori: a poor man's gut pathogen?. Gut Pathog. 2010, 2:2.
21. Köhler G., Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975, 256(5517):495.
22. Kottakis F., Papadopoulos G., Pappa E.V., Cordopatis P., Pentas S., Choli-Papadopoulou T. Helicobacter pylori neutrophil-activating protein activates neutrophils by its C-terminal region even without dodecamer formation, which is a prerequisite for DNA protection - novel approaches against Helicobacter pylori inflammation. FEBS J. 2008, 275:302.
23. Kottakis F., Befani C., Asiminas A., Kontou M., Koliakos G., Choli-Papadopoulou T. The C-terminal region of HPNAP activates neutrophils and promotes their adhesion to endothelial cells. Helicobacter 2009, 14:177.
24. Long M., Luo J., Li Y., Zeng F.Y., Li M. Detection and evaluation of antibodies against neutrophil-activating protein of Helicobacter pylori in patients with gastric cancer. World J. Gastroenterol. 2009, 15:2381.
25. Malfertheiner P., Schultze V., Rosenkranz B., Kaufmann S.H., Ulrichs T., Novicki D., Norelli F., Contorni M., Peppoloni S., Berti D., Tornese D., Ganju J., Palla E., Rappuoli R., Scharschmidt B.F., Del Giudice G. Safety and immunogenicity of an intramuscular Helicobacter pylori vaccine in noninfected volunteers: a phase I study. Gastroenterology 2008, 135:787.
26. Mégraud F., Lehours P. Helicobacter pylori detection and antimicrobial susceptibility testing. Clin. Microbiol. Rev. 2007, 20:280.
27. Momynaliev K.T., Rogov S.I., Selezneva O.V., Chelysheva V.V., Akopian T.A., Govorun V.M. Comparative analysis of transcription profiles of Helicobacter pylori clinical isolates. Biochemistry (Mosc.) 2005, 70:383.
28. Montecucco C., de Bernard M. Molecular and cellular mechanisms of action of the vacuolating cytotoxin (VacA) and neutrophil-activating protein (HP-NAP) virulence factors of Helicobacter pylori. Microbes Infect. 2003, 5:715.
29. Namavar F., Sparrius M., Veerman E.C., Appelmelk B.J., Vandenbroucke-Grauls C.M. Neutrophil-activating protein mediates adhesion of Helicobacter pylori to sulfated carbohydrates on high-molecular-weight salivary mucin. Infect. Immun. 1998, 66:444.
30. 13C-urea breath test in monitoring Helicobacter pylori eradication therapy. World J. Gastroenterol. 2005, 11:5878.
31. Polenghi A., Bossi F., Fischetti F., Durigutto P., Cabrelle A., Tamassia N., Cassatella M.A., Montecucco C., Tedesco F., de Bernard M. The neutrophil-activating protein of Helicobacter pylori crosses endothelia to promote neutrophil adhesion in vivo. J. Immunol. 2007, 178:1312.
32. Satin B., Del Giudice G., Della Bianca V., Dusi S., Laudanna C., Tonello F., Kelleher D., Rappuoli R., Montecucco C., Rossi F. The neutrophil-activating protein (HP-NAP) of Helicobacter pylori is a protective antigen and a major virulence factor. J. Exp. Med. 2000, 191:1467.
33. Teneberg S., Miller-Podraza H., Lampert H.C., Evans D.J., Evans D.G., Danielsson D., Karlsson K.A. Carbohydrate binding specificity of the neutrophil-activating protein of Helicobacter pylori. J. Biol. Chem. 1997, 272:19067.
34. Tonello F., Dundon W.G., Satin B., Molinari M., Tognon G., Grandi G., Del Giudice G., Rappuoli R., Montecucco C. The Helicobacter pylori neutrophil-activating protein is an iron-binding protein with dodecameric structure. Mol. Microbiol. 1999, 34:238.
35. Wang C.A., Liu Y.C., Du S.Y., Lin C.W., Fu H.W. Helicobacter pylori neutrophil-activating protein promotes myeloperoxidase release from human neutrophils. Biochem. Biophys. Res. Commun. 2008, 377:52.
36. Zanotti G., Papinutto E., Dundon W., Battistutta R., Seveso M., Giudice G., Rappuoli R., Montecucco C. Structure of the neutrophil-activating protein from Helicobacter pylori. J. Mol. Biol. 2002, 323:125.