The C-terminal region of HPNAP activates neutrophils and promotes their adhesion to endothelial cells

Helicobacter

Volumn 14, Issue 3, 2009, Pages 177-179

  Kottakis, Filippos ^a   Befani, Christina ^a   Asiminas, Antonios ^a   Kontou, Maria ^b   Koliakos, Georgios ^a   Choli Papadopoulou, Theodora ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b UNIVERSITY OF THESSALY   (Greece)

Author keywords

AGPs; Anti inflammatory therapy; Helicobacter; HPNAP

Indexed keywords

BACTERIAL PROTEIN; HELICOBACTER PYLORI NEUTROPHIL ACTIVATING PROTEIN; LIPOPOLYSACCHARIDE; PLASMID VECTOR; RESIN; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STIMULATION; CLONING; CONTROLLED STUDY; ENDOTHELIUM CELL; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE ACTIVATION; MOLECULAR CLONING; NEUTROPHIL; PISTACIA LENTISCUS; PRIORITY JOURNAL; PURIFICATION;

BACTERIAL PROTEINS; CELL ADHESION; ENDOTHELIAL CELLS; HELICOBACTER PYLORI; HUMANS; INFANT, NEWBORN; NEUTROPHILS;

HELICOBACTER; HELICOBACTER PYLORI; PISTACIA LENTISCUS;

EID: 65649108140     PISSN: 10834389     EISSN: 15235378     Source Type: Journal    
DOI: 10.1111/j.1523-5378.2009.00678.x     Document Type: Article

References (7)

1. Dundon WG, Nishioka H, Polenghi A, et al. The neutrophil-activating protein of Helicobacter pylori. Int J Med Microbiol 2002 291 : 545 50. (Pubitemid 34206835)
2. Amedei A, Cappon A, Codolo G, et al. The neutrophil-activating protein of Helicobacter pylori promotes Th1 immune responses. J Clin Invest 2006 116 : 1092 101.
3. Kottakis F, Papadopoulos G, Pappa EV, Cordopatis P, Pentas S, Choli-Papadopoulou T. Helicobacter pylori neutrophil-activating protein activates neutrophils by its C-terminal region even without dodecamer formation, which is a prerequisite for DNA protection - novel approaches against Helicobacter pylori inflammation. FEBS J 2008 275 : 302 17.
4. Kottakis F, Lamari F, Matragkou C, Zachariadis G, Karamanos N, Choli-Papadopoulou T. Arabino-galactan proteins from Pistacia lentiscus var. chia: isolation, characterization and biological function. Amino Acids 2008 34 : 413 20.
5. Jaffe EA, Nachman RL, Becker CG, Minick CR. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 1973 52 : 2745 56.
6. Malfertheiner P, Schultze V, Rosenkranz B, et al. Safety and immunogenicity of an intramuscular Helicobacter pylori vaccine in noninfected volunteers: a phase I study. Gastroenterology 2008 135 : 787 95.
7. Al-Habbal MJ, Al-Habbal Z, Huwez FU. A double-blind controlled clinical trial of mastic and placebo in the treatment of duodenal ulcer. Clin Exp Pharmacol Physiol 1984 11 : 541 4. (Pubitemid 15190343)