Olfaction, dyskinesia and profile of weight change in Parkinson's disease: Identifying neurodegenerative phenotypes

Parkinsonism and Related Disorders

Volumn 18, Issue 8, 2012, Pages 964-970

  Sharma, Jagdish C ^a,b   Turton, Janice ^c  

^a LINCOLN COUNTY HOSPITAL   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c KING S MILL HOSPITAL   (United Kingdom)

Author keywords

Olfaction; Parkinson's disease; Phenotype; Weight

Indexed keywords

LEVODOPA;

AGED; AGING; ANOSMIA; ARTICLE; DISEASE SEVERITY; DYSKINESIA; FEMALE; HUMAN; HYPOSMIA; MAJOR CLINICAL STUDY; MALE; PARKINSON DISEASE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; SEX DIFFERENCE; SMELLING; WEIGHT CHANGE; WEIGHT GAIN; WEIGHT REDUCTION;

ADULT; AGED; AGED, 80 AND OVER; BODY WEIGHT; DYSKINESIAS; ENERGY INTAKE; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; NEURODEGENERATIVE DISEASES; PARKINSON DISEASE; PHENOTYPE; PROSPECTIVE STUDIES; SMELL; WEIGHT LOSS;

EID: 84865591706     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2012.05.004     Document Type: Article

References (29)

1. Chen H., Zhang S.M., Hernan M.A., Willett W.C., Ascherio A. Weight loss in Parkinson's disease. Ann Neurol 2003, 53:676-679.
2. Jankovic J., Wooten M., van der L.C., Jansson B. Lower body weight in Parkinson's disease. South Med J 1992, 85:351-354.
3. Markus H.S., Tomkins A.M., Stern G.M. Increased prevalence of undernutrition in Parkinson's disease and its relationship to clinical disease parameters. J Neural Transm Park Dis Dement Sect 1993, 5:117-125.
4. Bayer P.L., Palarino M.Y., Michalek D., Busenbark K., Koller W.C. Weight change and body composition in patients with Parkinson's disease. J Am Diet Assoc 1995, 95:979-983.
5. Durrieu G., llau M.E., Rascol O., Senard J.M., Rascol A., Montastruc J.L. Parkinson's disease and weight loss: a study with anthropometric and nutritional assessment. Clin Auton Res 1992, 2:153-157.
6. Lorefalt B., Gonawiak W., Pelhagen S., Toss G., Unosson M., Granerus A.K. Factors of importance for weight loss in elderly patients with Parkinson's disease. Acta Neurol Scand 2004, 110:180-187.
7. Uc E.A., Struck L.K., Rodnitzky R.L., Zimmerman B., Dobson J., Evans W.J. Predictors of weight loss in Parkinson's disease. Mov Disord 2006, 21:930-936.
8. Bachmann C.G., Zapf A., Brunner E., Trenkwalder C. Dopaminergic treatment is associated with decreased body weight in patients with Parkinson's disease and dyskinesias. Eur J Neurol 2009, 16:895-901.
9. Cornelius B.G., Trenkwalder C. Body weight in patients with Parkinson's disease. Mov Disord 2006, 21:1824-1830.
10. Sharma J.C., Ross I.N., Rascol O., Brookes D. Relationship between body weight, levodopa and dyskinesia: the significance of levodopa dose per kilogram body weight. Eur J Neurol 2008, 15:493-496.
11. Sharma J.C., Macnamara L., Hasoon M., Vassallo M., Ross I.N. Cascade of levodopa dose and weight-related dyskinesia in Parkinson's disease (LD-WD-PD cascade). Parkinsonism Relat Disord 2006, 12:499-505.
12. Zappia M., Crescibene L., Arabia G., Nicoletti G., Bagalà A., Bastone L., et al. Body weight influences pharmacokinetics of levodopa in Parkinson's disease. Clin Neuropharmacol 2002, 25:79-82.
13. Sharma J.C., Bachmann C.G., Linazasoro G. Classifying risk factors for dyskinesia in Parkinson's disease. Parkinsonism Relat Disord 2010, 16:490-497.
14. Ansari K.A., Johnson A. Olfactory function in patients with Parkinson's disease. J Chron Dis 1975, 28:493-497.
15. Ward C.D., Hess W.A., Calne D.B. Olfactory impairment in Parkinson's disease. Neurology 1983, 33:943-946.
16. Doty R.L., Deems D., Steller S. Olfactory dysfunction in Parkinson's disease: a general deficit unrelated to neurologic signs, disease stage or disease duration. Neurology 1998, 38:1237-1244.
17. Braak H., Tredici K.D., Rub U., De Vos R.A., Jansen Steur E.N., Braak E. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 2003, 24:197-211.
18. Muller J., Mungersdorf M., Reuichmann H., Strechle G., Hummel T. Olfactory function in Parkinsonian syndromes. J Clin Neurosci 2002, 9:521-524.
19. Siderowf A., Jennings D., Connoly J., Doty R., Marek K., Stern M.B. Risk factors for Parkinson's disease and impaired olfaction in relatives of patients with Parkinson's disease. Mov Disord 2007, 22:2249-2255.
20. Hawkes C.H. Parkinson's disease and aging. Same or different process?. Mov Disord 2008, 23:47-53.
21. Kim J.Y., Lee W.Y., Chung E.J., Dhong H.J. Analysis of olfactory function and depth of olfactory sulcus in patients with Parkinson's disease. Mov Disord 2007, 22:1563-1566.
22. Tissingh G., Berendse H.W., Bergmans P., DeWaard R., Drukarch B., Stoof J.C., et al. Loss of olfaction in de novo and treated Parkinson's disease: possible implications for early diagnosis. Mov Disord 2001, 16:41-46.
23. Doty R.L., Sharman P., Dann M. Development of University of Pennsylvania smell identification test: a microencapsulated test of olfactory function. Physiol Behav 1984, 32:489-502.
24. Doty R.L., Marcus A., Lee W.W. Development of the 12 item cross-cultural smell identification test (CC-SIT). Laryngoscope 1996, 106:353-356.
25. Deeb J., Shah M., Muhammed N., Gunasekera R., Gannon K., Findley L.J., et al. A basic smell test is as sensitive as a dopamine transporter scan: comparison of olfaction, taste and DaTSCAN in the diagnosis of Parkinson's disease. QJM 2010, 103(12):941-952.
26. Braak H., Rub U., Gai W.P., Del T.K. Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen. J Neural Trans 2003, 110(50):517-536.
27. Hawkes C.H., Del Tredici K., Braak H. Parkinson's disease: a dual hit hypothesis. Neuropathol Appl Neurobiol 2007, 33(6):599-614.
28. Hawkes C.H. The prodromal phase of sporadic Parkinson's disease: does it exist and if so how long is it?. Mov Disord 2008, 23:1799-1807.
29. Stern M.B., Lang A., Poewe W. Toward a redefinition of Parkinson's disease. Mov Disord 2012, 27:54-60.