메뉴 건너뛰기




Volumn 43, Issue 9, 2012, Pages 2526-2534

Cerebrovascular disease and mechanisms of cognitive impairment: Evidence from clinicopathological studies in humans

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ALZHEIMER DISEASE; ASTROCYTOSIS; BLOOD BRAIN BARRIER; BRAIN ATROPHY; BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN NECROSIS; CADASIL; CEREBROVASCULAR DISEASE; CLINICAL FEATURE; COGNITIVE DEFECT; DEMYELINATION; DISEASE ASSOCIATION; FAMILIAL DISEASE; GLIOSIS; HIPPOCAMPUS; HISTOPATHOLOGY; HUMAN; HYALINE DEGENERATION; LACUNAR STROKE; LIPOID PROTEINOSIS; MICROANGIOPATHY; MULTIINFARCT DEMENTIA; NEUROPATHOLOGY; NEUROTRANSMISSION; PELIZAEUS MERZBACHER DISEASE; PRIORITY JOURNAL; PSYCHOMETRY; REVIEW; VASCULAR AMYLOIDOSIS; VASCULAR COGNITIVE IMPAIRMENT; WHITE MATTER;

EID: 84865575181     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.112.655803     Document Type: Review
Times cited : (173)

References (97)
  • 1
    • 0016137385 scopus 로고
    • Multi-infarct dementia. A cause of mental deterioration in the elderly
    • Hachinski VC, Lassen NA, Marshall J. Multi-infarct dementia. A cause of mental deterioration in the elderly. Lancet. 1974;2:207-210.
    • (1974) Lancet , vol.2 , pp. 207-210
    • Hachinski, V.C.1    Lassen, N.A.2    Marshall, J.3
  • 2
    • 0027534657 scopus 로고
    • Vascular dementia: Diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop
    • Roman GC, Tatemichi TK, Erkinjuntti T, Cummings JL, Masdeu JC, Garcia JH, et al. Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology. 1993;43: 250-260.
    • (1993) Neurology , vol.43 , pp. 250-260
    • Roman, G.C.1    Tatemichi, T.K.2    Erkinjuntti, T.3    Cummings, J.L.4    Masdeu, J.C.5    Garcia, J.H.6
  • 3
    • 33748352752 scopus 로고    scopus 로고
    • National Institute of Neurological Disorders and Stroke-Canadian Stroke Network vascular cognitive impairment harmonization standards
    • Hachinski V, Iadecola C, Petersen RC, Breteler MM, Nyenhuis DL, Black SE, et al. National Institute of Neurological Disorders and Stroke-Canadian Stroke Network vascular cognitive impairment harmonization standards. Stroke. 2006;37:2220-2241.
    • (2006) Stroke , vol.37 , pp. 2220-2241
    • Hachinski, V.1    Iadecola, C.2    Petersen, R.C.3    Breteler, M.M.4    Nyenhuis, D.L.5    Black, S.E.6
  • 4
    • 80052400687 scopus 로고    scopus 로고
    • Vascular contributions to cognitive impairment and dementia: A statement for healthcare professionals from the American Heart Association/American Stroke Association
    • Gorelick PB, Scuteri A, Black SE, Decarli C, Greenberg SM, Iadecola C, et al. Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42:2672-2713.
    • (2011) Stroke , vol.42 , pp. 2672-2713
    • Gorelick, P.B.1    Scuteri, A.2    Black, S.E.3    Decarli, C.4    Greenberg, S.M.5    Iadecola, C.6
  • 6
    • 0014326852 scopus 로고
    • Observations on the brains of non-demented old people
    • Tomlinson BE, Blessed G, Roth M. Observations on the brains of non-demented old people. J Neurol Sci. 1968;7:331-356.
    • (1968) J Neurol Sci , vol.7 , pp. 331-356
    • Tomlinson, B.E.1    Blessed, G.2    Roth, M.3
  • 7
    • 0014851803 scopus 로고
    • Observations on the brains of demented old people
    • Tomlinson BE, Blessed G, Roth M. Observations on the brains of demented old people. J Neurol Sci. 1970;11:205-242.
    • (1970) J Neurol Sci , vol.11 , pp. 205-242
    • Tomlinson, B.E.1    Blessed, G.2    Roth, M.3
  • 8
    • 0036327146 scopus 로고    scopus 로고
    • Vascular dementia revisited: Diagnosis, pathogenesis, treatment, and prevention
    • Roman GC. Vascular dementia revisited: diagnosis, pathogenesis, treatment, and prevention. Med Clin North Am. 2002;86:477-499.
    • (2002) Med Clin North Am , vol.86 , pp. 477-499
    • Roman, G.C.1
  • 9
    • 0034603512 scopus 로고    scopus 로고
    • The role of cerebral ischemia in Alzheimer's disease
    • Kalaria RN. The role of cerebral ischemia in Alzheimer's disease. Neu-robiol Aging. 2000;21:321-330.
    • (2000) Neu-robiol Aging , vol.21 , pp. 321-330
    • Kalaria, R.N.1
  • 11
    • 43549099984 scopus 로고    scopus 로고
    • Cerebrovascular disease and dementia
    • Knopman DS. Cerebrovascular disease and dementia. Br J Radiol. 2007; 80:S121-S127.
    • (2007) Br J Radiol. , vol.80
    • Knopman, D.S.1
  • 12
    • 0028279493 scopus 로고
    • Pathology and pathophysiology of cerebrovascular dementia: Pure subgroups of obstructive and hypoperfusive etiology
    • Brun A. Pathology and pathophysiology of cerebrovascular dementia: pure subgroups of obstructive and hypoperfusive etiology. Dementia. 1994;5:145-147.
    • (1994) Dementia. , vol.5 , pp. 145-147
    • Brun, A.1
  • 13
    • 84863559802 scopus 로고    scopus 로고
    • Atheromatous disease in small intracerebral vessels, microinfarcts and dementia
    • Kalaria RN, Perry RH, O'Brien J, Jaros E. Atheromatous disease in small intracerebral vessels, microinfarcts and dementia. Neuropathol Appl Neu-robiol. 2012;38:505-508.
    • (2012) Neuropathol Appl Neu-robiol , vol.38 , pp. 505-508
    • Kalaria, R.N.1    Perry, R.H.2    O'Brien, J.3    Jaros, E.4
  • 14
    • 48249087678 scopus 로고    scopus 로고
    • Vascular diseases
    • Love S, Louis D, Ellison D, eds Oxford, UK: Oxford University Press
    • Ferrer I, Kaste M, Kalimo H. Vascular diseases. In: Love S, Louis D, Ellison D, eds. Greenfield's Neuropathology. Oxford, UK: Oxford University Press; 2008:121-240.
    • (2008) Greenfield's Neuropathology , pp. 121-240
    • Ferrer, I.1    Kaste, M.2    Kalimo, H.3
  • 16
    • 33751219894 scopus 로고    scopus 로고
    • Circle of Willis atherosclerosis: Association with Alzheimer's disease, neuritic plaques and neurofibrillary tangles
    • Beach TG, Wilson JR, Sue LI, Newell A, Poston M, Cisneros R, et al. Circle of Willis atherosclerosis: association with Alzheimer's disease, neuritic plaques and neurofibrillary tangles. Acta Neuropathol. 2007;113: 13-21.
    • (2007) Acta Neuropathol , vol.113 , pp. 13-21
    • Beach, T.G.1    Wilson, J.R.2    Sue, L.I.3    Newell, A.4    Poston, M.5    Cisneros, R.6
  • 18
    • 77953533246 scopus 로고    scopus 로고
    • Cerebral small vessel disease: From pathogenesis and clinical characteristics to therapeutic challenges
    • Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol. 2010;9:689-701.
    • (2010) Lancet Neurol , vol.9 , pp. 689-701
    • Pantoni, L.1
  • 19
    • 34247899069 scopus 로고    scopus 로고
    • Morphometric analysis of arteriolar tortuosity in human cerebral white matter of preterm, young, and aged subjects
    • Thore CR, Anstrom JA, Moody DM, Challa VR, Marion MC, Brown WR. Morphometric analysis of arteriolar tortuosity in human cerebral white matter of preterm, young, and aged subjects. J Neuropathol Exp Neurol. 2007;66:337-345.
    • (2007) J Neuropathol Exp Neurol , vol.66 , pp. 337-345
    • Thore, C.R.1    Anstrom, J.A.2    Moody, D.M.3    Challa, V.R.4    Marion, M.C.5    Brown, W.R.6
  • 20
    • 0033786827 scopus 로고    scopus 로고
    • Pathology of small vessel stroke
    • Lammie GA. Pathology of small vessel stroke. Br Med Bull. 2000;56: 296-306.
    • (2000) Br Med Bull , vol.56 , pp. 296-306
    • Lammie, G.A.1
  • 21
    • 33645809129 scopus 로고    scopus 로고
    • Perivascular nerves and the regulation of cerebrovascular tone
    • Hamel E. Perivascular nerves and the regulation of cerebrovascular tone. J Appl Physiol. 2006;100:1059-1064.
    • (2006) J Appl Physiol. , vol.100 , pp. 1059-1064
    • Hamel, E.1
  • 22
    • 34247877828 scopus 로고    scopus 로고
    • Association of small-vessel disease with dilatative arteriopathy of the brain: Neuropathologic evidence
    • Pico F, Labreuche J, Seilhean D, Duyckaerts C, Hauw JJ, Amarenco P. Association of small-vessel disease with dilatative arteriopathy of the brain: neuropathologic evidence. Stroke. 2007;38:1197-1202.
    • (2007) Stroke. , vol.38 , pp. 1197-1202
    • Pico, F.1    Labreuche, J.2    Seilhean, D.3    Duyckaerts, C.4    Hauw, J.J.5    Amarenco, P.6
  • 24
    • 58549098084 scopus 로고    scopus 로고
    • Blood-brain barrier: Ageing and microvascular disease\-systematic review and meta-analysis
    • Farrall AJ, Wardlaw JM. Blood-brain barrier: ageing and microvascular disease\-systematic review and meta-analysis. Neurobiol Aging. 2009; 30:337-352.
    • (2009) Neurobiol Aging , vol.30 , pp. 337-352
    • Farrall, A.J.1    Wardlaw, J.M.2
  • 25
    • 0036938594 scopus 로고    scopus 로고
    • A comparative study on the expression of cyclooxygenase and 5-lipoxygen-ase during cerebral ischemia in humans
    • Tomimoto H, Shibata M, Ihara M, Akiguchi I, Ohtani R, Budka H. A comparative study on the expression of cyclooxygenase and 5-lipoxygen-ase during cerebral ischemia in humans. Acta Neuropathol. 2002;104: 601-607.
    • (2002) Acta Neuropathol. , vol.104 , pp. 601-607
    • Tomimoto, H.1    Shibata, M.2    Ihara, M.3    Akiguchi, I.4    Ohtani, R.5    Budka, H.6
  • 26
    • 84865455487 scopus 로고    scopus 로고
    • Pathology of lacunar ischaemic stroke in humans\-a systematic review
    • Published online ahead of print February 13, 2012. DOI: 10.1111/j.1750-3639.2012.00575.x
    • Bailey EL, Smith C, Sudlow CL, Wardlaw JM. Pathology of lacunar ischaemic stroke in humans\-a systematic review. Brain Pathol. Published online ahead of print February 13, 2012. DOI: 10.1111/j.1750-3639.2012.00575.x.
    • Brain Pathol
    • Bailey, E.L.1    Smith, C.2    Sudlow, C.L.3    Wardlaw, J.M.4
  • 27
    • 66849129538 scopus 로고    scopus 로고
    • Neuropathological correlates of temporal pole white matter hyperinten-sities in CADASIL
    • Yamamoto Y, Ihara M, Tham C, Low RW, Slade JY, Moss T, et al. Neuropathological correlates of temporal pole white matter hyperinten-sities in CADASIL. Stroke. 2009;40:2004-2011.
    • (2009) Stroke , vol.40 , pp. 2004-2011
    • Yamamoto, Y.1    Ihara, M.2    Tham, C.3    Low, R.W.4    Slade, J.Y.5    Moss, T.6
  • 28
    • 0023688264 scopus 로고
    • Accuracy of the clinical diagnosis of vascular dementia: A prospective clinical and postmortem neuropathological study
    • Erkinjuntti T, Haltia M, Palo J, Sulkava R, Paetau A. Accuracy of the clinical diagnosis of vascular dementia: a prospective clinical and postmortem neuropathological study. J Neurol Neurosurg Psychiatry. 1988; 51:1037-1044.
    • (1988) J Neurol Neurosurg Psychiatry , vol.51 , pp. 1037-1044
    • Erkinjuntti, T.1    Haltia, M.2    Palo, J.3    Sulkava, R.4    Paetau, A.5
  • 29
    • 44649131215 scopus 로고    scopus 로고
    • Morphologic diagnosis of 'vascular dementia'\-a critical update
    • Jellinger KA. Morphologic diagnosis of 'vascular dementia'\-a critical update. J Neurol Sci. 2008;270:1-12.
    • (2008) J Neurol Sci , vol.270 , pp. 1-12
    • Jellinger, K.A.1
  • 30
    • 0033994552 scopus 로고    scopus 로고
    • Neuropathological substrates of dementia and depression in vascular dementia, with a particular focus on cases with small infarct volumes
    • Ballard C, McKeith I, O'Brien J, Kalaria R, Jaros E, Ince P, et al. Neuropathological substrates of dementia and depression in vascular dementia, with a particular focus on cases with small infarct volumes. Dement Geriatr Cogn Disord. 2000;11:59-65.
    • (2000) Dement Geriatr Cogn Disord , vol.11 , pp. 59-65
    • Ballard, C.1    McKeith, I.2    O'Brien, J.3    Kalaria, R.4    Jaros, E.5    Ince, P.6
  • 32
    • 18744366040 scopus 로고    scopus 로고
    • Cerebrovascular pathology and dementia in autopsied Honolulu-Asia Aging Study participants
    • White L, Petrovitch H, Hardman J, Nelson J, Davis DG, Ross GW, et al. Cerebrovascular pathology and dementia in autopsied Honolulu-Asia Aging Study participants. Ann N Y Acad Sci. 2002;977:9-23.
    • (2002) Ann N y Acad Sci. , vol.977 , pp. 9-23
    • White, L.1    Petrovitch, H.2    Hardman, J.3    Nelson, J.4    Davis, D.G.5    Ross, G.W.6
  • 33
    • 0842310806 scopus 로고    scopus 로고
    • Cortical microinfarcts and demyelination significantly affect cognition in brain aging
    • Kovari E, Gold G, Herrmann FR, Canuto A, Hof PR, Michel JP, et al. Cortical microinfarcts and demyelination significantly affect cognition in brain aging. Stroke. 2004;35:410-414.
    • (2004) Stroke. , vol.35 , pp. 410-414
    • Kovari, E.1    Gold, G.2    Herrmann, F.R.3    Canuto, A.4    Hof, P.R.5    Michel, J.P.6
  • 34
    • 35648934983 scopus 로고    scopus 로고
    • Identification of Alzheimer and vascular lesion thresholds for mixed dementia
    • Gold G, Giannakopoulos P, Herrmann FR, Bouras C, Kovari E. Identification of Alzheimer and vascular lesion thresholds for mixed dementia. Brain. 2007;130:2830-2836.
    • (2007) Brain. , vol.130 , pp. 2830-2836
    • Gold, G.1    Giannakopoulos, P.2    Herrmann, F.R.3    Bouras, C.4    Kovari, E.5
  • 35
    • 0036327648 scopus 로고    scopus 로고
    • Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease
    • Suter OC, Sunthorn T, Kraftsik R, Straubel J, Darekar P, Khalili K, et al. Cerebral hypoperfusion generates cortical watershed microinfarcts in Alzheimer disease. Stroke. 2002;33:1986-1992.
    • (2002) Stroke , vol.33 , pp. 1986-1992
    • Suter, O.C.1    Sunthorn, T.2    Kraftsik, R.3    Straubel, J.4    Darekar, P.5    Khalili, K.6
  • 36
    • 34547821883 scopus 로고    scopus 로고
    • Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons
    • Schneider JA, Boyle PA, Arvanitakis Z, Bienias JL, Bennett DA. Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons. Ann Neurol. 2007;62:59-66.
    • (2007) Ann Neurol , vol.62 , pp. 59-66
    • Schneider, J.A.1    Boyle, P.A.2    Arvanitakis, Z.3    Bienias, J.L.4    Bennett, D.A.5
  • 38
    • 0029665096 scopus 로고    scopus 로고
    • Apo-lipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cere-brovascular pathology associated with Alzheimer's disease
    • Premkumar DR, Cohen DL, Hedera P, Friedland RP, Kalaria RN. Apo-lipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cere-brovascular pathology associated with Alzheimer's disease. Am J Pathol. 1996;148:2083-2095.
    • (1996) Am J Pathol , vol.148 , pp. 2083-2095
    • Premkumar, D.R.1    Cohen, D.L.2    Hedera, P.3    Friedland, R.P.4    Kalaria, R.N.5
  • 39
    • 0035915621 scopus 로고    scopus 로고
    • Pathological correlates of late-onset dementia in a multi-centre, community-based population in England and Wales
    • MRC-CFAS. Pathological correlates of late-onset dementia in a multi-centre, community-based population in England and Wales
    • MRC-CFAS. Pathological correlates of late-onset dementia in a multi-centre, community-based population in England and Wales. Neuropa-thology Group of the Medical Research Council Cognitive Function and Ageing Study. Lancet. 2001;357:169-175.
    • (2001) Lancet , vol.357 , pp. 169-175
  • 41
    • 0035385932 scopus 로고    scopus 로고
    • Advances in molecular genetics and pathology of cerebrovascular disorders
    • Kalaria RN. Advances in molecular genetics and pathology of cerebrovascular disorders. Trends Neurosci. 2001;24:392-400.
    • (2001) Trends Neurosci , vol.24 , pp. 392-400
    • Kalaria, R.N.1
  • 42
    • 0036130319 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy and vessel dysfunction
    • Greenberg SM. Cerebral amyloid angiopathy and vessel dysfunction. Cerebrovasc Dis. 2002;13(suppl 2):42-47.
    • (2002) Cerebrovasc Dis. , vol.13 , Issue.SUPPL. 2 , pp. 42-47
    • Greenberg, S.M.1
  • 43
    • 0035203856 scopus 로고    scopus 로고
    • Dementia in hereditary cerebral hemorrhage with amyloidosis-Dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles
    • Natte R, Maat-Schieman ML, Haan J, Bornebroek M, Roos RA, van Duinen SG. Dementia in hereditary cerebral hemorrhage with amyloidosis-Dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles. Ann Neurol. 2001;50:765-772.
    • (2001) Ann Neurol , vol.50 , pp. 765-772
    • Natte, R.1    Maat-Schieman, M.L.2    Haan, J.3    Bornebroek, M.4    Roos, R.A.5    Van Duinen, S.G.6
  • 44
    • 0023254674 scopus 로고
    • Cerebral amyloid angiopathy. A critical review
    • Vinters HV. Cerebral amyloid angiopathy. A critical review. Stroke. 1987;18:311-324.
    • (1987) Stroke , vol.18 , pp. 311-324
    • Vinters, H.V.1
  • 45
    • 72949090601 scopus 로고    scopus 로고
    • Epidemiological pathology of dementia: Attributable-risks at death in the Medical Research Council Cognitive Function and Ageing Study
    • Matthews FE, Brayne C, Lowe J, McKeith I, Wharton SB, Ince P. Epidemiological pathology of dementia: attributable-risks at death in the Medical Research Council Cognitive Function and Ageing Study. PLoS Med. 2009;6:e1000180.
    • (2009) PLoS Med. , vol.6
    • Matthews, F.E.1    Brayne, C.2    Lowe, J.3    McKeith, I.4    Wharton, S.B.5    Ince, P.6
  • 46
    • 77953026083 scopus 로고    scopus 로고
    • Vascular pathology in the aged human brain
    • Grinberg LT, Thal DR. Vascular pathology in the aged human brain. Acta Neuropathol. 2010;119:277-290.
    • (2010) Acta Neuropathol , vol.119 , pp. 277-290
    • Grinberg, L.T.1    Thal, D.R.2
  • 47
    • 33746463940 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy and cortical microinfarcts as putative substrates of vascular dementia
    • Haglund M, Passant U, Sjobeck M, Ghebremedhin E, Englund E. Cerebral amyloid angiopathy and cortical microinfarcts as putative substrates of vascular dementia. Int J Geriatr Psychiatry. 2006;21:681-687.
    • (2006) Int J Geriatr Psychiatry. , vol.21 , pp. 681-687
    • Haglund, M.1    Passant, U.2    Sjobeck, M.3    Ghebremedhin, E.4    Englund, E.5
  • 48
    • 4344653778 scopus 로고    scopus 로고
    • Severe cerebral amyloid angiopathy characterizes an underestimated variant of vascular dementia
    • Haglund M, Sjobeck M, Englund E. Severe cerebral amyloid angiopathy characterizes an underestimated variant of vascular dementia. Dement Geriatr Cogn Disord. 2004;18:132-137.
    • (2004) Dement Geriatr Cogn Disord , vol.18 , pp. 132-137
    • Haglund, M.1    Sjobeck, M.2    Englund, E.3
  • 49
    • 67749130804 scopus 로고    scopus 로고
    • Cortical microinfarcts in Alzheimer's disease and subcortical vascular dementia
    • Okamoto Y, Ihara M, Fujita Y, Ito H, Takahashi R, Tomimoto H. Cortical microinfarcts in Alzheimer's disease and subcortical vascular dementia. Neuroreport. 2009;20:990-996.
    • (2009) Neuroreport , vol.20 , pp. 990-996
    • Okamoto, Y.1    Ihara, M.2    Fujita, Y.3    Ito, H.4    Takahashi, R.5    Tomimoto, H.6
  • 50
    • 84857922274 scopus 로고    scopus 로고
    • Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts
    • Okamoto Y, Yamamoto T, Kalaria RN, Senzaki H, Maki T, Hase Y, et al. Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts. Acta Neuropathol. 2012;123:381-394.
    • (2012) Acta Neuropathol , vol.123 , pp. 381-394
    • Okamoto, Y.1    Yamamoto, T.2    Kalaria, R.N.3    Senzaki, H.4    Maki, T.5    Hase, Y.6
  • 51
    • 77953025222 scopus 로고    scopus 로고
    • Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies
    • Ihara M, Polvikoski TM, Hall R, Slade JY, Perry RH, Oakley AE, et al. Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies. Acta Neuropathol. 2010;119:579-589.
    • (2010) Acta Neuropathol , vol.119 , pp. 579-589
    • Ihara, M.1    Polvikoski, T.M.2    Hall, R.3    Slade, J.Y.4    Perry, R.H.5    Oakley, A.E.6
  • 52
    • 2942654724 scopus 로고    scopus 로고
    • Topographical and cytopathological lesion analysis of the white matter in Binswanger's disease brains
    • Akiguchi I, Tomimoto H, Wakita H, Kawamoto Y, Matsuo A, Ohnishi K, et al. Topographical and cytopathological lesion analysis of the white matter in Binswanger's disease brains. Acta Neuropathol. 2004;107: 563-570.
    • (2004) Acta Neuropathol. , vol.107 , pp. 563-570
    • Akiguchi, I.1    Tomimoto, H.2    Wakita, H.3    Kawamoto, Y.4    Matsuo, A.5    Ohnishi, K.6
  • 54
    • 34249790312 scopus 로고    scopus 로고
    • Vascular dementia in leukoaraiosis may be a consequence of capillary loss not only in the lesions, but in normal-appearing white matter and cortex as well
    • Brown WR, Moody DM, Thore CR, Challa VR, Anstrom JA. Vascular dementia in leukoaraiosis may be a consequence of capillary loss not only in the lesions, but in normal-appearing white matter and cortex as well. J Neurol Sci. 2007;257:62-66.
    • (2007) J Neurol Sci. , vol.257 , pp. 62-66
    • Brown, W.R.1    Moody, D.M.2    Thore, C.R.3    Challa, V.R.4    Anstrom, J.A.5
  • 55
    • 33745148241 scopus 로고    scopus 로고
    • White matter lesions in an unselected cohort of the elderly: Molecular pathology suggests origin from chronic hypoperfusion injury
    • Fernando MS, Simpson JE, Matthews F, Brayne C, Lewis CE, Barber R, et al. White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury. Stroke. 2006;37:1391-1398.
    • (2006) Stroke , vol.37 , pp. 1391-1398
    • Fernando, M.S.1    Simpson, J.E.2    Matthews, F.3    Brayne, C.4    Lewis, C.E.5    Barber, R.6
  • 56
    • 0033202045 scopus 로고    scopus 로고
    • Overlap between pathology of Alzheimer disease and vascular dementia
    • Kalaria RN, Ballard C. Overlap between pathology of Alzheimer disease and vascular dementia. Alzheimer Dis Assoc Disord. 1999;13(suppl 3):S115-S123.
    • (1999) Alzheimer Dis Assoc Disord. , vol.13 , Issue.SUPPL. 3
    • Kalaria, R.N.1    Ballard, C.2
  • 58
    • 60549083472 scopus 로고    scopus 로고
    • Microarray RNA expression analysis of cerebral white matter lesions reveals changes in multiple functional pathways
    • Simpson JE, Hosny O, Wharton SB, Heath PR, Holden H, Fernando MS, et al. Microarray RNA expression analysis of cerebral white matter lesions reveals changes in multiple functional pathways. Stroke. 2009;40: 369-375.
    • (2009) Stroke. , vol.40 , pp. 369-375
    • Simpson, J.E.1    Hosny, O.2    Wharton, S.B.3    Heath, P.R.4    Holden, H.5    Fernando, M.S.6
  • 59
    • 34447134893 scopus 로고    scopus 로고
    • White matter lesions in an unselected cohort of the elderly: Astrocytic, microglial and oligodendrocyte precursor cell responses
    • Simpson JE, Fernando MS, Clark L, Ince PG, Matthews F, Forster G, et al. White matter lesions in an unselected cohort of the elderly: astrocytic, microglial and oligodendrocyte precursor cell responses. Neuropathol Appl Neurobiol. 2007;33:410-419.
    • (2007) Neuropathol Appl Neurobiol , vol.33 , pp. 410-419
    • Simpson, J.E.1    Fernando, M.S.2    Clark, L.3    Ince, P.G.4    Matthews, F.5    Forster, G.6
  • 60
    • 33645835674 scopus 로고    scopus 로고
    • Postmortem examination of vascular lesions in cognitive impairment: A survey among neuropathological services
    • Pantoni L, Sarti C, Alafuzoff I, Jellinger K, Munoz DG, Ogata J, et al. Postmortem examination of vascular lesions in cognitive impairment: a survey among neuropathological services. Stroke. 2006;37:1005-1009.
    • (2006) Stroke , vol.37 , pp. 1005-1009
    • Pantoni, L.1    Sarti, C.2    Alafuzoff, I.3    Jellinger, K.4    Munoz, D.G.5    Ogata, J.6
  • 61
    • 0028086345 scopus 로고
    • Hippocampal sclerosis: A common pathological feature of dementia in very old (> or =80 years of age) humans
    • Dickson DW, Davies P, Bevona C, Van Hoeven KH, Factor SM, Grober E, et al. Hippocampal sclerosis: a common pathological feature of dementia in very old (> or =80 years of age) humans. Acta Neuropathol. 1994;88:212-221.
    • (1994) Acta Neuropathol , vol.88 , pp. 212-221
    • Dickson, D.W.1    Davies, P.2    Bevona, C.3    Van Hoeven, K.H.4    Factor, S.M.5    Grober, E.6
  • 63
    • 20444429015 scopus 로고    scopus 로고
    • Correlates of hippocampal neuron number in Alzheimer's disease and ischemic vascular dementia
    • Zarow C, Vinters HV, Ellis WG, Weiner MW, Mungas D, White L, et al. Correlates of hippocampal neuron number in Alzheimer's disease and ischemic vascular dementia. Ann Neurol. 2005;57:896-903.
    • (2005) Ann Neurol , vol.57 , pp. 896-903
    • Zarow, C.1    Vinters, H.V.2    Ellis, W.G.3    Weiner, M.W.4    Mungas, D.5    White, L.6
  • 64
    • 0036259003 scopus 로고    scopus 로고
    • Patients with vascular dementia due to microvascular pathology have significant hippocampal neuronal loss
    • Kril JJ, Patel S, Harding AJ, Halliday GM. Patients with vascular dementia due to microvascular pathology have significant hippocampal neuronal loss. J Neurol Neurosurg Psychiatry. 2002;72:747-751.
    • (2002) J Neurol Neurosurg Psychiatry , vol.72 , pp. 747-751
    • Kril, J.J.1    Patel, S.2    Harding, A.J.3    Halliday, G.M.4
  • 65
    • 84857644548 scopus 로고    scopus 로고
    • Hippocampal neuronal atrophy and cognitive function in delayed poststroke and aging-related dementias
    • Gemmell E, Bosomworth H, Allan L, Hall R, Khundakar A, Oakley AE, et al. Hippocampal neuronal atrophy and cognitive function in delayed poststroke and aging-related dementias. Stroke. 2012;43:808-814.
    • (2012) Stroke. , vol.43 , pp. 808-814
    • Gemmell, E.1    Bosomworth, H.2    Allan, L.3    Hall, R.4    Khundakar, A.5    Oakley, A.E.6
  • 66
    • 0028212340 scopus 로고
    • Synaptophysin immunoreactivity of the cortical neuropil in vascular dementia of Binswanger type compared with the dementia of Alzheimer type and nondemented controls
    • Zhan SS, Beyreuther K, Schmitt HP. Synaptophysin immunoreactivity of the cortical neuropil in vascular dementia of Binswanger type compared with the dementia of Alzheimer type and nondemented controls. Dementia. 1994;5:79-87.
    • (1994) Dementia , vol.5 , pp. 79-87
    • Zhan, S.S.1    Beyreuther, K.2    Schmitt, H.P.3
  • 67
    • 83755182698 scopus 로고    scopus 로고
    • Long term incidence of dementia, predictors of mortality and pathological diagnosis in older stroke survivors
    • Allan LM, Rowan EN, Firbank MJ, Thomas AJ, Parry SW, Polvikoski TM, et al. Long term incidence of dementia, predictors of mortality and pathological diagnosis in older stroke survivors. Brain. 2012;134: 3716-3727.
    • (2012) Brain , vol.134 , pp. 3716-3727
    • Allan, L.M.1    Rowan, E.N.2    Firbank, M.J.3    Thomas, A.J.4    Parry, S.W.5    Polvikoski, T.M.6
  • 68
    • 33644942362 scopus 로고    scopus 로고
    • Quantification of Alzheimer pathology in ageing and dementia: Age-related accumulation of amyloid-beta(42) peptide in vascular dementia
    • Lewis H, Beher D, Cookson N, Oakley A, Piggott M, Morris CM, et al. Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-beta(42) peptide in vascular dementia. Neuropathol Appl Neurobiol. 2006;32:103-118.
    • (2006) Neuropathol Appl Neurobiol , vol.32 , pp. 103-118
    • Lewis, H.1    Beher, D.2    Cookson, N.3    Oakley, A.4    Piggott, M.5    Morris, C.M.6
  • 69
    • 0033546881 scopus 로고    scopus 로고
    • Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease
    • Esiri MM, Nagy Z, Smith MZ, Barnetson L, Smith AD. Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease. Lancet. 1999;354:919-920.
    • (1999) Lancet. , vol.354 , pp. 919-920
    • Esiri, M.M.1    Nagy, Z.2    Smith, M.Z.3    Barnetson, L.4    Smith, A.D.5
  • 71
    • 1842528072 scopus 로고    scopus 로고
    • Cerebral infarctions and the likelihood of dementia from Alzheimer disease pathology
    • Schneider JA, Wilson RS, Bienias JL, Evans DA, Bennett DA. Cerebral infarctions and the likelihood of dementia from Alzheimer disease pathology. Neurology. 2004;62:1148-1155.
    • (2004) Neurology. , vol.62 , pp. 1148-1155
    • Schneider, J.A.1    Wilson, R.S.2    Bienias, J.L.3    Evans, D.A.4    Bennett, D.A.5
  • 72
    • 84857030932 scopus 로고    scopus 로고
    • National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: A practical approach
    • Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathol. 2012;123:1-11.
    • (2012) Acta Neuropathol , vol.123 , pp. 1-11
    • Montine, T.J.1    Phelps, C.H.2    Beach, T.G.3    Bigio, E.H.4    Cairns, N.J.5    Dickson, D.W.6
  • 73
    • 84886631402 scopus 로고
    • Neurotransmitter enzyme abnormalities in senile dementia. Choline acetyltransferase and glutamic acid decarboxylase activities in necropsy brain tissue
    • Perry EK, Gibson PH, Blessed G, Perry RH, Tomlinson BE. Neurotransmitter enzyme abnormalities in senile dementia. Choline acetyltransferase and glutamic acid decarboxylase activities in necropsy brain tissue. J Neurol Sci. 1977;34:247-265.
    • (1977) J Neurol Sci , vol.34 , pp. 247-265
    • Perry, E.K.1    Gibson, P.H.2    Blessed, G.3    Perry, R.H.4    Tomlinson, B.E.5
  • 75
    • 33750022878 scopus 로고    scopus 로고
    • Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia
    • Roman GC, Kalaria RN. Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia. Neurobiol Aging. 2006;27: 1769-1785.
    • (2006) Neurobiol Aging , vol.27 , pp. 1769-1785
    • Roman, G.C.1    Kalaria, R.N.2
  • 77
    • 0022881466 scopus 로고
    • The nucleus basalis of Meynert in multi-infarct (vascular) dementia
    • Mann DM, Yates PO, Marcyniuk B. The nucleus basalis of Meynert in multi-infarct (vascular) dementia. Acta Neuropathol. 1986;71:332-337.
    • (1986) Acta Neuropathol , vol.71 , pp. 332-337
    • Mann, D.M.1    Yates, P.O.2    Marcyniuk, B.3
  • 80
    • 67650021262 scopus 로고    scopus 로고
    • Increased binding to 5-HT1A and 5-HT2A receptors is associated with large vessel infarction and relative preservation of cognition
    • Elliott MS, Ballard CG, Kalaria RN, Perry R, Hortobagyi T, Francis PT. Increased binding to 5-HT1A and 5-HT2A receptors is associated with large vessel infarction and relative preservation of cognition. Brain. 2009;132:1858-1865.
    • (2009) Brain , vol.132 , pp. 1858-1865
    • Elliott, M.S.1    Ballard, C.G.2    Kalaria, R.N.3    Perry, R.4    Hortobagyi, T.5    Francis, P.T.6
  • 81
    • 33846583895 scopus 로고    scopus 로고
    • Hereditary forms of vascular dementia
    • Kalimo H, ed Basel, Switzerland: ISN Neuropath Press
    • Kalimo H, Kalaria RN. Hereditary forms of vascular dementia. In: Kalimo H, ed. Cerebrovascular Diseases, Pathology & Genetics. Basel, Switzerland: ISN Neuropath Press; 2005:324-384.
    • (2005) Cerebrovascular Diseases, Pathology & Genetics , pp. 324-384
    • Kalimo, H.1    Kalaria, R.N.2
  • 84
    • 0036019164 scopus 로고    scopus 로고
    • CADASIL: A common form of hereditary arteriopathy causing brain infarcts and dementia
    • Kalimo H, Ruchoux MM, Viitanen M, Kalaria RN. CADASIL: a common form of hereditary arteriopathy causing brain infarcts and dementia. Brain Pathol. 2002;12:371-384.
    • (2002) Brain Pathol , vol.12 , pp. 371-384
    • Kalimo, H.1    Ruchoux, M.M.2    Viitanen, M.3    Kalaria, R.N.4
  • 85
    • 0030670874 scopus 로고    scopus 로고
    • Neuropathological assessment of the lesions of significance in vascular dementia
    • Esiri MM, Wilcock GK, Morris JH. Neuropathological assessment of the lesions of significance in vascular dementia. J Neurol Neurosurg Psychiatry. 1997;63:749-753.
    • (1997) J Neurol Neurosurg Psychiatry , vol.63 , pp. 749-753
    • Esiri, M.M.1    Wilcock, G.K.2    Morris, J.H.3
  • 86
    • 20444407153 scopus 로고    scopus 로고
    • Cognitive consequences of thalamic, basal ganglia, and deep white matter lacunes in brain aging and dementia
    • Gold G, Kovari E, Herrmann FR, Canuto A, Hof PR, Michel JP, et al. Cognitive consequences of thalamic, basal ganglia, and deep white matter lacunes in brain aging and dementia. Stroke. 2005;36:1184-1188.
    • (2005) Stroke , vol.36 , pp. 1184-1188
    • Gold, G.1    Kovari, E.2    Herrmann, F.R.3    Canuto, A.4    Hof, P.R.5    Michel, J.P.6
  • 87
    • 34147092550 scopus 로고    scopus 로고
    • Cortical microinfarcts and demyelination affect cognition in cases at high risk for dementia
    • Kovari E, Gold G, Herrmann FR, Canuto A, Hof PR, Bouras C, et al. Cortical microinfarcts and demyelination affect cognition in cases at high risk for dementia. Neurology. 2007;68:927-931.
    • (2007) Neurology. , vol.68 , pp. 927-931
    • Kovari, E.1    Gold, G.2    Herrmann, F.R.3    Canuto, A.4    Hof, P.R.5    Bouras, C.6
  • 88
    • 36148972426 scopus 로고    scopus 로고
    • Pathological correlates of dementia in a longitudinal, population-based sample of aging
    • Sonnen JA, Larson EB, Crane PK, Haneuse S, Li G, Schellenberg GD, et al. Pathological correlates of dementia in a longitudinal, population-based sample of aging. Ann Neurol. 2007;62:406-413.
    • (2007) Ann Neurol , vol.62 , pp. 406-413
    • Sonnen, J.A.1    Larson, E.B.2    Crane, P.K.3    Haneuse, S.4    Li, G.5    Schellenberg, G.D.6
  • 90
    • 75149115045 scopus 로고    scopus 로고
    • Brain lesions at autopsy in older Japanese-American men as related to cognitive impairment and dementia in the final years of life: A summary report from the Honolulu-Asia aging study
    • White L. Brain lesions at autopsy in older Japanese-American men as related to cognitive impairment and dementia in the final years of life: a summary report from the Honolulu-Asia aging study. J Alzheimers Dis. 2009;18:713-725.
    • (2009) J Alzheimers Dis , vol.18 , pp. 713-725
    • White, L.1
  • 91
    • 75149173859 scopus 로고    scopus 로고
    • Neuropathological correlates of dementia in over-80-year-old brain donors from the population-based Cambridge city over-75s cohort (CC75C) study
    • Brayne C, Richardson K, Matthews FE, Fleming J, Hunter S, Xuereb JH, et al. Neuropathological correlates of dementia in over-80-year-old brain donors from the population-based Cambridge city over-75s cohort (CC75C) study. J Alzheimers Dis. 2009;18:645-658.
    • (2009) J Alzheimers Dis. , vol.18 , pp. 645-658
    • Brayne, C.1    Richardson, K.2    Matthews, F.E.3    Fleming, J.4    Hunter, S.5    Xuereb, J.H.6
  • 94
    • 78049377229 scopus 로고    scopus 로고
    • Alterations of the blood-brain barrier in cerebral white matter lesions in the ageing brain
    • Simpson JE, Wharton SB, Cooper J, Gelsthorpe C, Baxter L, Forster G, et al. Alterations of the blood-brain barrier in cerebral white matter lesions in the ageing brain. Neurosci Lett. 2011;486:246-251.
    • (2011) Neurosci Lett , vol.486 , pp. 246-251
    • Simpson, J.E.1    Wharton, S.B.2    Cooper, J.3    Gelsthorpe, C.4    Baxter, L.5    Forster, G.6
  • 95
    • 80055019036 scopus 로고    scopus 로고
    • Blood-brain barrier breakdown in acute and chronic cerebrovascular disease
    • Yang Y, Rosenberg GA. Blood-brain barrier breakdown in acute and chronic cerebrovascular disease. Stroke. 2011;42:3323-3328.
    • (2011) Stroke , vol.42 , pp. 3323-3328
    • Yang, Y.1    Rosenberg, G.A.2
  • 97
    • 57049154546 scopus 로고    scopus 로고
    • Lymphatic drainage of the brain and the pathophysiology of neurological disease
    • Weller RO, Djuanda E, Yow HY, Carare RO. Lymphatic drainage of the brain and the pathophysiology of neurological disease. Acta Neuropathol. 2009;117:1-14.
    • (2009) Acta Neuropathol , vol.117 , pp. 1-14
    • Weller, R.O.1    Djuanda, E.2    Yow, H.Y.3    Carare, R.O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.