Facile synthesis of a dimeric dipyrrole-polyamide and synergetic DNA-cleaving activity of its Cu(II) complex

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 18, 2012, Pages 5853-5856

  Zhou, Chun Qiong ^a   Lin, Yan Ling ^a   Chen, Jin Xiang ^a   Wang, Lu Sheng ^a   Yang, Na Na ^a   Zeng, Wei ^b   Chen, Wen Hua ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Cu(II) complex; Dipyrrole polyamide; DNA cleavage; Synthesis

Indexed keywords

1 METHYL 4 [(1 METHYL 4 NITRO 1H PYRROLE 2 CARBONYL)AMINO] 1HPYRROLE 2 CARBOXYLIC ACID; 2,2' (ETHANE 1,2 DIYLBIS(OXY))DIETHANAMINE; CARBOXYLIC ACID DERIVATIVE; COPPER COMPLEX; DIPYRROLE POLYAMIDE DERIVATIVE; ETHYLAMINE; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; ARTICLE; BINDING AFFINITY; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL REACTION; DNA CLEAVAGE; ELECTROSPRAY MASS SPECTROMETRY; INFRARED RADIATION; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROPHOTOMETRY; SYNTHESIS;

COPPER; DIMERIZATION; DNA CLEAVAGE; DNA, BACTERIAL; MOLECULAR STRUCTURE; NYLONS; ORGANOMETALLIC COMPOUNDS; PLASMIDS; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84865507507     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.07.085     Document Type: Article

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