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Volumn 22, Issue 10, 2012, Pages 1353-1362

Substrate specificity of 6-O-endosulfatase (Sulf-2) and its implications in synthesizing anticoagulant heparan sulfate

Author keywords

heparan sulfate; heparin; substrate specificity; sulfatase

Indexed keywords

ANTITHROMBIN; DISACCHARIDE; GLUCOSAMINE DERIVATIVE; HEPARAN SULFATE; POLYSACCHARIDE SULFATE; PROTEIN 6 O ENDOSULFATASE; RECOMBINANT ENZYME; SULFATASE; THROMBOCYTE FACTOR 4; UNCLASSIFIED DRUG; URONIC ACID;

EID: 84865480913     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cws092     Document Type: Article
Times cited : (26)

References (45)
  • 1
    • 0041671071 scopus 로고    scopus 로고
    • QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling
    • DOI 10.1083/jcb.200212083
    • Ai X, Do AT, Lozynska O, Kusche-Gullberg M, Lindahl U, Emerson CP, Jr. 2003. QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling. J Cell Biol. 162:341-351. (Pubitemid 36928846)
    • (2003) Journal of Cell Biology , vol.162 , Issue.2 , pp. 341-351
    • Ai, X.1    Do, A.-T.2    Lozynska, O.3    Kusche-Gullberg, M.4    Lindahl, U.5    Emerson Jr., C.P.6
  • 2
    • 33646188185 scopus 로고    scopus 로고
    • Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2
    • DOI 10.1074/jbc.M511902200
    • Ai X, Do AT, Kusche-Gullberg M, Lindahl U, Lu K, Emerson CP, Jr. 2006. Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2. J Biol Chem. 281:4969-4976. (Pubitemid 43847759)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.8 , pp. 4969-4976
    • Ai, X.1    Do, A.-T.2    Kusche-Gullberg, M.3    Lindahl, U.4    Lu, K.5    Emerson Jr., C.P.6
  • 3
    • 35548943609 scopus 로고    scopus 로고
    • SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation
    • DOI 10.1242/dev.007674
    • Ai X, Kitazawa T, Do AT, Kusche-Gullberg M, Labosky PA, Emerson CP, Jr. 2007. SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation. Development. 134:3327-3338. (Pubitemid 350018433)
    • (2007) Development , vol.134 , Issue.18 , pp. 3327-3338
    • Ai, X.1    Kitazawa, T.2    Do, A.-T.3    Kusche-Gullberg, M.4    Labosky, P.A.5    Emerson Jr., C.P.6
  • 4
    • 77951926334 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia
    • Arepally GM, Ortel TL. 2010. Heparin-induced thrombocytopenia. Annu Rev Med. 61:77-90.
    • (2010) Annu Rev Med. , vol.61 , pp. 77-90
    • Arepally, G.M.1    Ortel, T.L.2
  • 5
    • 0022368634 scopus 로고
    • Contribution of monosaccharide residues in heparin binding to antithrombin III
    • DOI 10.1021/bi00344a063
    • Atha DH, Lormeau JC, Petitou M, Rosenberg RD, Choay J. 1985. Contribution of monosaccharide residues in heparin binding to antithrombin III. Biochemistry. 24:6723-6729. (Pubitemid 16207156)
    • (1985) Biochemistry , vol.24 , Issue.23 , pp. 6723-6729
    • Atha, D.H.1    Lormeau, J.-C.2    Petitou, M.3
  • 6
    • 34548615858 scopus 로고    scopus 로고
    • Using an Enzymatic Combinatorial Approach to Identify Anticoagulant Heparan Sulfate Structures
    • DOI 10.1016/j.chembiol.2007.07.015, PII S1074552107002840
    • Chen J, Jones CL, Liu J. 2007. Using an enzymatic combinatorial approach to identify anticoagulant heparan sulfate structures. Chem Biol. 14:986-993. (Pubitemid 47404901)
    • (2007) Chemistry and Biology , vol.14 , Issue.9 , pp. 986-993
    • Chen, J.1    Jones, C.L.2    Liu, J.3
  • 7
    • 0028072969 scopus 로고
    • Characterization of a cell mutant specifically defective in the synthesis of anticoagulantly active heparan sulfate
    • Colliec-Jouault S, Shworak NW, Liu J, De Agostini AI, Rosenberg RD. 1994. Characterization of a cell mutant specifically defective in the synthesis of anticoagulantly active heparan sulfate. J Biol Chem. 271:24953-24958.
    • (1994) J Biol Chem , vol.271 , pp. 24953-24958
    • Colliec-Jouault, S.1    Shworak, N.W.2    Liu, J.3    De Agostini, A.I.4    Rosenberg, R.D.5
  • 10
    • 0035979765 scopus 로고    scopus 로고
    • Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase
    • DOI 10.1126/science.293.5535.1663
    • Dhoot GK, Gustafsson MK, Ai X, Sun W, Standiford DM, Emerson CP, Jr. 2001. Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase. Science. 293:1663-1666. (Pubitemid 32807846)
    • (2001) Science , vol.293 , Issue.5535 , pp. 1663-1666
    • Dhoot, G.K.1    Gustafsson, M.K.2    Ai, X.3    Sun, W.4    Standiford, D.M.5    Emerson Jr., C.P.6
  • 11
    • 29044433102 scopus 로고    scopus 로고
    • Characterization of the N-deacetylase domain from the heparan sulfate N-deacetylase/N-sulfotransferase 2
    • DOI 10.1016/j.bbrc.2005.11.142, PII S0006291X05026859
    • Duncan MB, Liu M, Fox C, Liu J. 2006. Characterization of the N-deacetylase domain from the heparan sulfate N-deacetylase/N-sulfotransferase 2. Biochem Biophys Res Commun. 339:1232-1237. (Pubitemid 41790595)
    • (2006) Biochemical and Biophysical Research Communications , vol.339 , Issue.4 , pp. 1232-1237
    • Duncan, M.B.1    Liu, M.2    Fox, C.3    Liu, J.4
  • 12
    • 0035997376 scopus 로고    scopus 로고
    • Order out of chaos: Assembly of ligand binding sites in heparan sulfate
    • DOI 10.1146/annurev.biochem.71.110601.135458
    • Esko JD, Selleck SB. 2002. Order out of chaos: Assembly of ligand binding sites in heparan sulfate. Annu Rev Biochem. 71:435-471. (Pubitemid 34800227)
    • (2002) Annual Review of Biochemistry , vol.71 , pp. 435-471
    • Esko, J.D.1    Selleck, S.B.2
  • 13
    • 33646345110 scopus 로고    scopus 로고
    • Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells
    • Feyerabend TB, Li JP, Lindahl U, Rodewald HR. 2006. Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells. Nat Chem Biol. 2:195-196.
    • (2006) Nat Chem Biol , vol.2 , pp. 195-196
    • Feyerabend, T.B.1    Li, J.P.2    Lindahl, U.3    Rodewald, H.R.4
  • 18
    • 34047121229 scopus 로고    scopus 로고
    • The heparanome-The enigma of encoding and decoding heparan sulfate sulfation
    • DOI 10.1016/j.jbiotec.2007.01.022, PII S0168165607001149
    • Lamanna WC, Kalus I, Padva M, Baldwin RJ, Merry CL, Dierks T. 2007. The heparanome-the enigma of encoding and decoding heparan sulfate. J Biotechnol. 129:290-307. (Pubitemid 46529030)
    • (2007) Journal of Biotechnology , vol.129 , Issue.2 , pp. 290-307
    • Lamanna, W.C.1    Kalus, I.2    Padva, M.3    Baldwin, R.J.4    Merry, C.L.R.5    Dierks, T.6
  • 19
    • 0025862954 scopus 로고
    • Analysis of affinity and structural selectivity in the binding of proteins to glycosaminoglycans: Development of a sensitive electrophoretic approach
    • Lee MK, Lander AD. 1991. Analysis of affinity and structural selectivity in the binding of proteins to glycosaminoglycans: Development of a sensitive electrophoretic approach. Proc Natl Acad Sci USA. 88: 2768-2772. (Pubitemid 21916500)
    • (1991) Proceedings of the National Academy of Sciences of the United States of America , vol.88 , Issue.7 , pp. 2768-2772
    • Lee, M.K.1    Lander, A.D.2
  • 21
    • 0032500662 scopus 로고    scopus 로고
    • The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate
    • DOI 10.1074/jbc.273.41.26265
    • Lind T, Tufaro F, McCormick C, Lindahl U, Lidholt K. 1998. The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate. J Biol Chem. 273:26265-26268. (Pubitemid 28471622)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.41 , pp. 26265-26268
    • Lind, T.1    Tufaro, F.2    McCormick, C.3    Lindahl, U.4    Lidholt, K.5
  • 24
    • 0033582432 scopus 로고    scopus 로고
    • Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities
    • Liu J, Shworak NW, Sinaÿ P, Schwartz JJ, Zhang L, Fritze LMS, Rosenberg RD. 1999. Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities. J Biol Chem. 274:5185-5192.
    • (1999) J Biol Chem , vol.274 , pp. 5185-5192
    • Liu, J.1    Shworak, N.W.2    Sinaÿ, P.3    Schwartz, J.J.4    Zhang, L.5    Fritze, L.M.S.6    Rosenberg, R.D.7
  • 25
    • 33846150651 scopus 로고    scopus 로고
    • Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2
    • DOI 10.1128/MCB.01279-06
    • Lum DH, Tan J, Rosen SD, Werb Z. 2007. Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2. Mol Cell Biol. 27: 678-688. (Pubitemid 46080133)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.2 , pp. 678-688
    • Lum, D.H.1    Tan, J.2    Rosen, S.D.3    Werb, Z.4
  • 26
    • 0033520448 scopus 로고    scopus 로고
    • Heparin dodecasaccharide binding to platelet factor-4 and growth-related protein-alpha
    • Mikhailov D, Young HC, Linhardt RJ, Mayo KH. 1999. Heparin dodecasaccharide binding to platelet factor-4 and growth-related protein-alpha. J Biol Chem. 274:25317-25329.
    • (1999) J Biol Chem , vol.274 , pp. 25317-25329
    • Mikhailov, D.1    Young, H.C.2    Linhardt, R.J.3    Mayo, K.H.4
  • 27
    • 0037147259 scopus 로고    scopus 로고
    • Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans
    • DOI 10.1074/jbc.M205131200
    • Morimoto-Tomita M, Uchimura K, Werb Z, Hemmerich S, Rosen SD. 2002. Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans. J Biol Chem. 277:49175-49185. (Pubitemid 36014346)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.51 , pp. 49175-49185
    • Morimoto-Tomita, M.1    Uchimura, K.2    Werb, Z.3    Hemmerich, S.4    Rosen, S.D.5
  • 28
    • 25144475549 scopus 로고    scopus 로고
    • Expression of a heparan sulfate remodeling enzyme, heparan sulfate 6-O-endosulfatase sulfatase FP2, in the rat nervous system
    • DOI 10.1016/j.devbrainres.2005.07.006, PII S0165380605002117
    • Nagamine S, Koike S, Keino-Masu K, Masu M. 2005. Expression of a heparan sulfate remodeling enzyme, heparan sulfate 6-O-endosulfatase sulfatase FP2, in the rat nervous system. Brain Res Dev Brain Res. 159:135-143. (Pubitemid 41338323)
    • (2005) Developmental Brain Research , vol.159 , Issue.2 , pp. 135-143
    • Nagamine, S.1    Koike, S.2    Keino-Masu, K.3    Masu, M.4
  • 29
    • 55349119506 scopus 로고    scopus 로고
    • Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells
    • Nawroth R, van Zante A, Cervantes S, McManus M, Hebrok M, Rosen SD. 2007. Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells. PLoS One. 2:e392.
    • (2007) PLoS One. , vol.2
    • Nawroth, R.1    Van Zante, A.2    Cervantes, S.3    McManus, M.4    Hebrok, M.5    Rosen, S.D.6
  • 30
    • 0036198049 scopus 로고    scopus 로고
    • Identification of a novel nonlysosomal sulphatase expressed in the floor plate, choroid plexus and cartilage
    • DOI 10.1046/j.1356-9597.2001.00502.x
    • Ohto T, Uchida H, Yamazaki H, Keino-Masu K, Matsui A, Masu M. 2002. Identification of a novel nonlysosomal sulphatase expressed in the floor plate, choroid plexus and cartilage. Genes Cells. 7:173-185. (Pubitemid 34213362)
    • (2002) Genes to Cells , vol.7 , Issue.2 , pp. 173-185
    • Ohto, T.1    Uchida, H.2    Yamazaki, H.3    Keino-Masu, K.4    Matsui, A.5    Masu, M.6
  • 31
    • 65349085618 scopus 로고    scopus 로고
    • Designing of biologically active heparan sulfate and heparin using an enzyme-based approach
    • Peterson S, Frick A, Liu J. 2009. Designing of biologically active heparan sulfate and heparin using an enzyme-based approach. Nat Prod Rep. 26:61-627.
    • (2009) Nat Prod Rep , vol.26 , pp. 61-627
    • Peterson, S.1    Frick, A.2    Liu, J.3
  • 32
    • 77952002191 scopus 로고    scopus 로고
    • Unraveling the specificity of heparanase utilizing synthetic substrates
    • Peterson SB, Liu J. 2010. Unraveling the specificity of heparanase utilizing synthetic substrates. J Biol Chem. 285:14504-14513.
    • (2010) J Biol Chem. , vol.285 , pp. 14504-14513
    • Peterson, S.B.1    Liu, J.2
  • 34
    • 39749201086 scopus 로고    scopus 로고
    • Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development
    • DOI 10.1002/dvdy.21423
    • Ratzka A, Kalus I, Moser M, Dierks T, Mundlos S, Vortkamp A. 2008. Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development. Dev Dyn. 237:339-353. (Pubitemid 351312107)
    • (2008) Developmental Dynamics , vol.237 , Issue.2 , pp. 339-353
    • Ratzka, A.1    Kalus, I.2    Moser, M.3    Dierks, T.4    Mundlos, S.5    Vortkamp, A.6
  • 35
    • 77955464418 scopus 로고    scopus 로고
    • Sulf-2: An extracellular modulator of cell signaling and a cancer target candidate
    • Rosen SD, Lemjabbar-Alaoui H. 2010. Sulf-2: An extracellular modulator of cell signaling and a cancer target candidate. Expert Opin Ther Targets. 14:935-949.
    • (2010) Expert Opin Ther Targets. , vol.14 , pp. 935-949
    • Rosen, S.D.1    Lemjabbar-Alaoui, H.2
  • 36
    • 0031442530 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans of the cardiovascular system: Specific structures emerge but how is synthesis regulated?
    • Rosenberg RD, Shworak NW, Liu J, Schwartz JJ, Zhang L. 1997. Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated? J Clin Invest. 100:S67-S75. (Pubitemid 28009550)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.SUPPL. 11
    • Rosenberg, R.D.1    Shworak, N.W.2    Liu, J.3    Schwartz, J.J.4    Zhang, L.5
  • 37
    • 0038677409 scopus 로고    scopus 로고
    • Compositional analysis and quantification of heparin and heparan sulfate by electrospray ionization ion trap mass spectrometry
    • DOI 10.1021/ac0340455
    • Saad OM, Leary JA. 2003. Compositional analysis and quantification f heparin and heparan sulfate by electrospray ionization ion trap mass spectrometry. Anal Chem. 75:2985-2995. (Pubitemid 36830424)
    • (2003) Analytical Chemistry , vol.75 , Issue.13 , pp. 2985-2995
    • Saad, O.M.1    Leary, J.A.2
  • 38
    • 0017189425 scopus 로고
    • Formation of anhydrosugars in the chemical depolymerization of heparin
    • Shively JE, Conrad HE. 1976. Formation of anhydrosugars in the chemical depolymerization of heparin. Biochemistry. 15:3932-3942.
    • (1976) Biochemistry , vol.15 , pp. 3932-3942
    • Shively, J.E.1    Conrad, H.E.2
  • 39
    • 69249154196 scopus 로고    scopus 로고
    • Functional consequences of the subdomain organization of the sulfs
    • Tang R, Rosen SD. 2009. Functional consequences of the subdomain organization of the sulfs. J Biol Chem. 284:21505-21514.
    • (2009) J Biol Chem , vol.284 , pp. 21505-21514
    • Tang, R.1    Rosen, S.D.2
  • 40
    • 30744451472 scopus 로고    scopus 로고
    • Glycosaminoglycans and their proteoglycans: Host-associated molecular patterns for initiation and modulation of inflammation
    • DOI 10.1096/fj.05-4682rev
    • Taylor KR, Gallo RL. 2006. Glycosaminoglycans and their proteoglycans: Host-associated molecular patterns for initiation and modulation of inflammation. FASB J. 20:9-22. (Pubitemid 43100470)
    • (2006) FASEB Journal , vol.20 , Issue.1 , pp. 9-22
    • Taylor, K.R.1    Gallo, R.L.2
  • 41
    • 0035253193 scopus 로고    scopus 로고
    • Heparan sulfate: Decoding a dynamic multifunctional cell regulator
    • DOI 10.1016/S0962-8924(00)01897-3, PII S0962892400018973
    • Turnbull J, Powell A, Guimond S. 2001. Heparan sulfate: Decoding a dynamic multifunctional cell regulator. Trends Cell Biol. 11:75-82. (Pubitemid 32144754)
    • (2001) Trends in Cell Biology , vol.11 , Issue.2 , pp. 75-82
    • Turnbull, J.1    Powell, A.2    Guimond, S.3
  • 42
    • 0019443244 scopus 로고
    • The structure of the capsular polysaccharide (K5 antigen) of urinary-tract-infective Escherichia coli 010:K5:H4. A polymer similar to desulfo-heparin
    • DOI 10.1111/j.1432-1033.1981.tb05343.x
    • Vann WF, Schmidt MA, Jann B, Jann K. 1981. The structure of the capsular polysaccharide (K5 antigen) of urinary-tract-infective Escherichia coli 010: K5:H4. Eur J Biochem. 116:359-364. (Pubitemid 11039072)
    • (1981) European Journal of Biochemistry , vol.116 , Issue.2 , pp. 359-364
    • Vann, W.F.1    Schmidt, M.A.2    Jann, B.3    Jann, K.4
  • 43
    • 1242272044 scopus 로고    scopus 로고
    • Domain-specific modification of heparan sulfate by Qsulf1 modulates the binding of the bone morphogenetic protein antagonist Noggin
    • DOI 10.1074/jbc.M310691200
    • Viviano BL, Paine-Saunders S, Gasiunas N, Gallagher J, Saunders S. 2004. Domain-specific modification of heparan sulfate by Qsulf1 modulates the binding of the bone morphogenetic protein antagonist Noggin. J Biol Chem. 279:5604-5611. (Pubitemid 38220587)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.7 , pp. 5604-5611
    • Viviano, B.L.1    Paine-Saunders, S.2    Gasiunas, N.3    Gallagher, J.4    Saunders, S.5
  • 44
    • 50649124502 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 induces heparan sulfate 6-O-endosulfatase 1 expression in vitro and in vivo
    • Yue X, Li X, Nguyen HT, Chin DR, Sullivan DE, Lasky JA. 2008. Transforming growth factor-beta1 induces heparan sulfate 6-O-endosulfatase 1 expression in vitro and in vivo. J Biol Chem. 283: 20397-20407.
    • (2008) J Biol Chem , vol.283 , pp. 20397-20407
    • Yue, X.1    Li, X.2    Nguyen, H.T.3    Chin, D.R.4    De, S.5    Lasky, J.A.6


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