Eudragit RL100 based microspheres for ocular administration of azelastine hydrochloride

Journal of Microencapsulation

Volumn 29, Issue 6, 2012, Pages 511-519

  Shinde, Ujwala A ^a   Shete, Jaykumar N ^a   Nair, Hema A ^a   Singh, Kavita H ^a  

^a BOMBAY COLLEGE OF PHARMACY   (India)

Author keywords

Allergic conjunctivitis; Azelastine hydrochloride; Eudragit RL 100; Ocular administration; Polymeric microspheres

Indexed keywords

AZELAST; AZELASTINE; EUDRAGIT; MICROSPHERE; UNCLASSIFIED DRUG;

ALLERGIC CONJUNCTIVITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMOSIS; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ADSORPTION; DRUG BINDING; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; EOSINOPHIL COUNT; EVAPORATION; FEMALE; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; HYPEREMIA; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; OCULAR PRURITUS; PARTICLE SIZE; RAT; SCANNING ELECTRON MICROSCOPY; ZETA POTENTIAL;

ADMINISTRATION, OPHTHALMIC; ANIMALS; ANTI-ALLERGIC AGENTS; CONJUNCTIVITIS, ALLERGIC; DELAYED-ACTION PREPARATIONS; FEMALE; MICROSPHERES; PARTICLE SIZE; PHTHALAZINES; POLYMETHACRYLIC ACIDS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84865475205     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.3109/02652048.2012.665088     Document Type: Article

References (21)

1. Ali Y, Lehmussaari K. Industrial perspective in ocular drug delivery. Adv Drug Deliv Rev, 2006;58:1258-68.
2. Al-Kassas R. Design and in vitro evaluation of gentamicin-Eudragit microspheres intended for intra-ocular administration. J Microencapsul, 2004;21(1):71-81. (Pubitemid 38180749)
3. Bourlais CL, Acar L, Zia H, Sado PA, Needham T, Leverge R. Ophthalmic drug delivery systems - Recent advances. Prog Retin Eye Res, 1998;17(1):33-58. (Pubitemid 28040752)
4. Das S, Suresh PK, Desmukh R. Design of Eudragit RL100 nanoparticles by nanoprecipitation method for ocular drug delivery. Nanomedicine, 2010;6(2):318-23.
5. Dillen K, Vandervoort J, Van den Mooter G, Ludwig A. Evaluation of ciprofloxacin-loaded Eudragit- RS100 or L100/PLGA nanoparticles. Int J Pharm, 2006;314(1):72-82.
6. Gaudana R, Jwala J, Boddu SH, Mitra AK. Recent perspectives in ocular drug delivery. Pharm Res, 2009;26(5):1197-216.
7. Haznedar S, Dortunc B. Preparation and in vitro evaluation of Eudragit microspheres containing acetazolamide. Int J Pharm, 2004;269(1):131-40. (Pubitemid 38032830)
8. Joshi A. Microparticulates for ophthalmic drug delivery. J Ocul Pharmacol, 1994;10(1):29-45. (Pubitemid 24119428)
9. Kachrimanis K, Nikolakakis I, Malamataris S. Spherical crystal agglomeration of ibuprofen by the solvent-change technique in presence of methacrylic polymers. J Pharm Sci, 2000;89(2):250-9. (Pubitemid 30120805)
10. Ludwig A. The use of mucoadhesive polymers in ocular drug delivery. Adv Drug Deliv Rev, 2005;57:1595-639. (Pubitemid 41443472)
11. Maghsoodi M. Physicomechanical properties of naproxen-loaded microparticles prepared from Eudragit L100. AAPS PharmSciTech, 2009;10(1):120-8.
12. Mateović-Rojnik T, Frlan R, Bogataj M, Bukovec P, Mrhar A. Effect of preparation temperature in solvent evaporation process on Eudragit RS microsphere properties. Chem Pharm Bull, 2005;53(1):143-6. (Pubitemid 40879859)
13. McGinity JW, O'Donnell PB. Preparation of microspheres by the solvent evaporation technique. Adv Drug Deliv Rev, 1997;28(1):25-42. (Pubitemid 27497672)
14. Minami K, Kamei C. A chronic model for evaluating the itching associated with allergic conjunctivitis in rats. Int Immunopharmacol, 2004;4(1):101-8. (Pubitemid 38223819)
15. Pignatello R, Bucolo C, Ferrara P, Maltese A, Puleo A, Puglisi G. Eudrgit RS100 nanosuspensions for the ophthalmic controlled delivery of ibuprofen. Euro J Pharm Sci, 2002;16(1-2):53-61. (Pubitemid 34756782)
16. Pignatello R, Ricupero N, Bucolo C, Maugeri F, Maltese A, Puglisi G. Preparation and characterization of Eudragit retard nanosuspensions for the ocular delivery of cloricromene. AAPS PharmSciTech, 2006;7(1):E27.
17. Rosca ID, Watari F, Uo M. Microparticle formation and its mechanism in single and double emulsion solvent evaporation. J Control Release, 2004;99(2):271-80. (Pubitemid 39222112)
18. Stern ME, Siemasko K, Gao J, Duong A, Beauregard C, Calder V, Niederkorn JY. Role of interferon-gamma in a mouse model of allergic conjunctivitis. Invest Ophthalmol Vis Sci, 2005;46(9):3239-46. (Pubitemid 44264311)
19. Ubrich N, Schmidt C, Bodmeier R, Hoffman M, Maincent P. Oral evaluation in rabbits of cyclosporine-loaded Eudragit RS or RL nanoparticles. Int J Pharm, 2005;288(1):169-75. (Pubitemid 39662725)
20. Vasir JK, Tambwekar K, Garg S. Bioadhesive microspheres as a controlled drug delivery system. Int J Pharm, 2003;255:13-32. (Pubitemid 36369587)
21. Zimmer A, Kreuter J. Microspheres and nanoparticles used in ocular delivery systems. Adv Drug Deliv Rev, 1995;16:61-73.