Covalent attachment of P15 peptide to titanium surfaces enhances cell attachment, spreading, and osteogenic gene expression

Journal of Orthopaedic Research

Volumn 30, Issue 10, 2012, Pages 1626-1633

  Liu, Qinyi ^a   Limthongkul, Worawat ^b   Sidhu, Gursukhmandeep ^c   Zhang, Jun ^a,d   Vaccaro, Alexander ^c   Shenck, Ryan ^d   Hickok, Noreen ^d   Shapiro, Irving ^d   Freeman, Theresa ^d  

^a THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^b CHULALONGKORN UNIVERSITY   (Thailand)

^c ROTHMAN INSTITUTE   (United States)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

differentiation; implant; integrin; osseointegration; osteoblast; P15; peptide; titanium

Indexed keywords

ALPHA2 INTEGRIN; BONE SIALOPROTEIN; COLLAGEN TYPE 1; FOCAL ADHESION KINASE; OSTEOCALCIN; OSTEOPONTIN; PROTEIN P15; TITANIUM; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2;

ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; BONE REGENERATION; CELL ADHESION; CELL DIFFERENTIATION; CELL GROWTH; CELL MATURATION; CELL PROLIFERATION; CELL SPREADING; CONTROLLED STUDY; COVALENT BOND; CYTOTOXICITY; ENZYME ACTIVATION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MESENCHYME CELL; MITOCHONDRIAL MEMBRANE; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; CELL ADHESION; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; COLLAGEN; FOCAL ADHESION KINASE 1; GENE EXPRESSION; HUMANS; INTEGRIN ALPHA2; MICE; OSSEOINTEGRATION; OSTEOBLASTS; OSTEOGENESIS; PEPTIDE FRAGMENTS; PROSTHESES AND IMPLANTS; SIGNAL TRANSDUCTION; TITANIUM;

EID: 84865458731     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22116     Document Type: Article

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