Histomorphometric evaluation of natural mineral combined with a synthetic cell-binding peptide (P-15) in critical-size defects in the rat calvaria

International Journal of Oral and Maxillofacial Implants

Volumn 23, Issue 6, 2008, Pages 1063-1070

  Artzi, Zvi ^a   Kozlovsky, Avital ^a   Nemcovsky, Carlos E ^a   Moses, Ofer ^a   Tal, Haim ^a   Rohrer, Michael D ^b   Prasad, Hari S ^c   Weinreb, Miron ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Bovine bone mineral; Cell binding peptide; Critical size defect; Guided bone regeneration; Histomorphometry; PepGen P 15

Indexed keywords

BIO GIDE; BIO-GIDE; BIOMATERIAL; COLLAGEN; PEPGEN P 15; PEPGEN P-15;

ANIMAL; ARTICLE; ARTIFICIAL MEMBRANE; BONE DENSITY; BONE DEVELOPMENT; BONE DISEASE; BONE MATRIX; BONE PROSTHESIS; BONE REGENERATION; CATTLE; METHODOLOGY; PATHOLOGY; PHYSIOLOGY; RAT; SKULL; TIME; TISSUE REGENERATION; WISTAR RAT;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE DENSITY; BONE DISEASES; BONE MATRIX; BONE REGENERATION; BONE SUBSTITUTES; CATTLE; COLLAGEN; GUIDED TISSUE REGENERATION; MEMBRANES, ARTIFICIAL; OSTEOGENESIS; RATS; RATS, WISTAR; SKULL; TIME FACTORS;

EID: 66149098935     PISSN: 08822786     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. tsaksson S, Alberius P, Klinge B. Influence of three alloplastic materials on calvarial bone healing. An experimental evaluation of HTR-polymer, lactomer beads, and a carrier gel. Int J Oral Maxillofac Surg 1993;22:375-381.
2. Naaman NB, Ouhayoun JP. Bone formation with discs or particles of natural coral skeleton plus polyglactin 910 mesh: Histologic evaluation in rat calvaria. Int J Oral Maxillofac Implants 1998 13:115-120.
3. Chesmel KD, Branger J, Wertheim H, Scarborough N. Healing response to various forms of human demineralized bone matrix in athymic rat cranial defects. J Oral Maxillofac Surg 1998;56:857-863.
4. Buser D, Hoffmann B, Bernard JP, Lussi A, Mettler D, Schenk RK. Evaluation of filling materials in membrane-protected bone defects. A comparative histomorpho-metric study in the mandible of miniature pigs. Clin Oral Implants Res 1998;9: 137-150.
5. Bhatnagar RS, Qian JJ, Gough CA.The role in cell binding of a beta-bend within the triple helical region in collagen alpha 1 (I) chain: Structural and biological evidence for conformational tautomerism on fiber surface. J Biomol Struct Dyn 1997; 14:547-560.
6. Bhatnagar RS.Qian JJ, Wedrychowska A, Sadeghi M, Wu YM, Smith N. Design of biomimetic habitats for tissue engineering with P-15, a synthetic peptide analogue of collagen.Tissue Eng 1999;5:53-65.
7. Nguyen H, Qian JJ, Bhatnagar RS, Li S. Enhanced cell attachment and osteoblastic activity by P-15 peptide-coated matrix in hydrogels.Biochem Biophys Res Commun 2003;311:179-186.
8. Yang XB, Bhatnagar RS, Li S, Oreffo RO. Biomimetic collagen scaffolds for human bone cell growth and differentiation.Tis- sue Eng 2004, 10:1148-1159.
9. Yukna RA, Callan DP, Krauser JT, et al. Multi-center clinical evaluation of combination anorganic bovine-derived hydroxyapatite matrix (ABM)/cell binding peptide (P-15) as a bone replacement graft material in human periodontal osseous defects. 6-month results. J Periodontol 1998;69:655-663.
10. Krauser JT, Rohrer MD, Wallace SS. Human histologic and his- tomorphometric analysis comparing OsteoGraf/N with Pep- Gen P-15 in the maxillary sinus elevation procedure: A case report. Implant Dent 2000;9:298-302.
11. Yukna RA, Krauser JT, Callan DP, Evans GH, Cruz R, Martin M. Multi-center clinical comparison of combination anorganic bovine-derived hydroxyapatite matrix (ABM)/cell binding peptide (P-15) and ABM in human periodontal osseous defects.6-month results.J Periodontol 2000;71:1671-1679.
12. Barboza EP, de Souza RO, Caúla AL, Neto LG, Caúla Fde O, Duarte ME. Bone regeneration of localized chronic alveolar defects utilizing cell binding peptide associated with anorganic bovine-derived bone mineral: a clinical and histological study. J Periodontol 2002;73:1153-1159.
13. Yukna RA, Krauser JT, Callan DP, Evans GH, Cruz R, Martin M. Thirty-six month follow-up of 25 patients treated with combination anorganic bovine-derived hydroxyapatite matrix (ABM)/cell-binding peptide (P-15) bone replacement grafts in human infrabony defects. I. Clinical findings. J Periodontol 2002;73:123-128.
14. Yukna R, Salinas TJ, Carr RF. Periodontal regeneration following use of ABM/P-15: A case report. Int J Periodontics Restorative Dent 2002;22:146-155.
15. Walters SP, Greenwell H, Hill M, Drisko C, Pickman K, Scheetz JP. Comparison of porous and non-porous teflon membranes plus a xenograft in the treatment of vertical osseous defects: A clinical reentry study. J Periodontol 2003, 74:1161-1168.
16. Hahn J, Rohrer MD.Tofe AJ. Clinical, radiographic, histologic, and histo-morphometric comparison of PepGen P-15 particulate and PepGen P-15 flow in extraction sockets: A same- mouth case study. Implant Dent 2003;12:170-174.
17. Tehemar S, Hanes P, Sharawy M. Enhancement of osseointe- gration of implants placed into extraction sockets of healthy and periodontally diseased teeth by using graft material, an ePTFE membrane, or a combination. Clin Implant Dent Relat Res 2003;5:193-211.
18. Radhakrishnan S, Anusuya CN.Comparative clinical evaluation of combination anorganic bovine-derived hydroxyapatite matrix (ABM)/cell binding peptide (P-15) and open flap debridement (DEBR) in human periodontal osseous defects: A 6 month pilot study. J Int Acad Periodontol 2004;6:101-107.
19. Hahn J. 8-year onlay bone graft and ridge augmentation with PepGen P-15: A clinical and radiographic case study. Implant Dent 2004;13:228-231.
20. Degidi M, Piattelli M, Scarano A, lezzi G, Piattelli A. Maxillary sinus augmentation with a synthetic cell-binding peptide: histological and histomorpho-metrical results in humans. J Oral Implantol 2004;30:376-383.
21. Gelbart M, Friedman R, Burlui V, Rohrer M, Atkinson B. Maxillary sinus augmentation using a peptide-modified graft material in three mixtures: A prospective human case series of histologic and histomorphometric results. Implant Dent 2005;14: 185-193.
22. Philippart P, Daubie V, Pochet R. Sinus grafting using recombinant human tissue factor, platelet-rich plasma gel, autologous bone, and anorganic bovine bone mineral xenograft: Histologic analysis and case reports. Int J Oral Maxillofac Implants 2005;20:274-281.
23. Yeung RW, Jin LJ, Pang M, Pow E. Human histologic and electromicroscopic analysis with synthetic peptide enhanced hydroxyapatite in the maxillary sinus elevation procedure: A case report. Implant Dent 2005;14:237-241.
24. Thompson DM, Rohrer MD, Prasad HS. Comparison of bone grafting materials in human extraction sockets: Clinical, histologic, and histomorphometric evaluations. Implant Dent 2006;15:89-96.
25. Scarano A, lezzi G, Petrone G, et al. Cortical bone regeneration with a synthetic cell-binding peptide: A histologic and histo- morphometric pilot study. Implant Dent 2003;12:318-324.
26. Vastardis S, Yukna RA, Mayer ET, Atkinson BL. Periodontal regeneration with peptide-enhanced anorganic bone matrix in particulate and putty form in dogs. J Periodontol 2005;76: 1690-1696.
27. Artzi Z, Weinreb M, Tal H, et al. Experimental intrabony and periodontal defects treated with natural mineral combined with a synthetic cell-binding peptide in the canine: Morphometry evaluations.J Periodontol 2006, 77:1658-1664.
28. Schmitz JP, Hollinger JO.The critical size defect as an experimental model for cranio-mandibulofacial nonunions. Clin Orthop Relat Res 1986;205:299-308.
29. Hollinger JO, Kleinschmidt JC.The critical size defect as an experimental model to test bone repair materials. J Craniofac Surg 1990;1:60-68.
30. Bosch C, Melsen B, Gibbons R, Vargervik K. Human recombinant transforming growth factor-beta 1 in healing of calvarial bone defects. J Craniofac Surg 1996, 7:300-310.
31. Bosch C, Melsen B.Vargervik K. Importance of the critical-size bone defect in testing bone-regenerating materials. J Craniofac Surg 1998;9:310-316.
32. Mardas N, Kostopoulos L, Karring T. Bone and suture regeneration in calvarial defects by e-PTFE-membranes and demineralized bone matrix and the impact on calvarial growth: An experimental study in the rat. J Craniofac Surg 2002;13: 453-462; discussion 462-464.
33. Gosain AK, Song L, Yu P, et al.Osteogenesis in cranial defects: reassessment of the concept of critical size and the expression of TGF-beta isoforms. Plast Reconstr Surg 2000;106: 360-371. (Pubitemid 30640457)
34. Blom EJ, Klein-Nulend J, Yin L, vanWaas MA, Burger EH.Trans- forming growth factor-betal incorporated in calcium phosphate cement stimulates osteotransductivity in rat calvarial bone defects. Clin Oral Implants Res 2001;12:609-616
35. Cacciafesta V, Dalstra M, Bosch C, Melsen B, Andreassen "FT. Growth hormone treatment promotes guided bone regeneration in rat calvarial defects. Eur J Orthod 2001;23:733-740.
36. Verna C, Dalstra M, Wikesj ;154 ; UM, Trombelli L, Bosch C. Healing patterns in calvarial bone defects following guided bone regeneration in rats. A micro-CT scan analysis. J Clin Periodontol 2002;29:865-870.
37. Zanchetta P, Lagarde N.Guezennec J. Systemic effects on bone healing of a new hyaluronic acid-like bacterial exopolysaccharide.Calcif Tissue Int 2003, 73:232-236. (Pubitemid 37152883)
38. Donos N, Lang NP, Karoussis IK, Bosshardt DJonetti M, Kostopoulos L. Effect of GBR in combination with depro- teinized bovine bone mineral and/or enamel matrix proteins on the healing of critical-size defects. Clin Oral Implants Res 2004;15:101-111.
39. Aalami OO, Nacamuli RP, Lenton KA, et al. Applications of a mouse model of calvarial healing: Differences in regenerative abilities of juveniles and adults. Plast Reconstr Surg 2004;114: 713-720.
40. Aybar Odstrcil A, Territoriale E.Missana L.An experimental model in calvaria to evaluate bone therapies. Acta Odontol Latinoam 2005;18:63-67.
41. Donath K, Breuner G. A method for the study of undecalcified bone and teeth with attached soft tissues.The Sage-Schliff (sawing and grinding) technique. J Oral Pathol 1982;11: 318-326.
42. Marden U, Hollinger JO, Chaudhari A, TurekT, Schaub RG.Ron E. Recombinant human bone morphogenic protein-2 is superior to demineralized bone matrix in repairing craniotomy defects in rats.J Biomed Mater Res 1994, 28:1127-1138.
43. Lim SC, Lee MJ, Yeo HH. Effects of various implant materials on regeneration of calvarial defects in rats. Pathol Int 2000;50: 594-602.
44. 44. Linde A, Hedner E. Recombinant bone morphogenic protein-2 enhances bone healing, guided by osteopromotive e-PTFE membranes: An experimental study in rats. Calcif Tissue Int 1995;56:549-553.
45. Mukherjee DP.Tunkle AS, Roberts RA, Clavenna A, Rogers S, Smith D. An animal evaluation of a paste of chitosan gluta- mate and hydroxyapatite as a synthetic bone graft material. J Biomed Mater Res B Appl Biomater 2003;67:603-609.
46. Suzuki O, Kamakura S, Katagiri T, et al. Bone formation enhanced by implanted octacalcium phosphate involving conversion into Ca-deficient hydroxyapatite. Biomaterials 2006;27:2671-2681.
47. Montjovent MO, Mathieu L, Schmoekel H, et al. Repair of critical size defects in the rat cranium using ceramic-reinforced PLA scaffolds obtained by supercritical gas foaming. J Biomed Mater Res A 2007, 83:41-51.
48. Develioglu H, Saraydin SU, Dupoirieux L, Sahin ZD. Histological findings of long-term healing of the experimental defects by application of a synthetic biphasic ceramic in rats.J Biomed Mater Res A 2007;80:505-508.
49. Furlaneto FA, Nagata MJ, Fucini SE, DeliberadorTM, Okamoto T, Messora MR. Bone healing in critical-size defects treated with bioactive glass/calcium sulfate: a histologic and histo- metric study in rat calvaria. Clin Oral Implants Res 2007;18: 311-318.
50. Lin Y, Tang W, Wu L, et al. Bone regeneration by BMP-2 enhanced adipose stem cells loading on alginate gel. His- tochem Cell Biol 2008;129:203-210.
51. Poehling S, Pippig SD, Hellerbrand K, Siedler M, Schiitz A, Dony C. Superior effect of MD05, beta-tricalcium phosphate coated with recombinant human growth/ differentiation factor-5, compared to conventional bone substitutes in the rat calvarial defect model. J Periodontol 2006;77:1582-1590.
52. Artzi Z, Weinreb M, Givol N, , et al.Biomaterial resorption rate and healing site morphology of inorganic bovine bone and beta-tricalcium phosphate in the canine: a 24-month longitudinal histologic study and morphometric analysis. Int J Oral Maxillofac Implants 2004;19:357-368.
53. Tal H, Artzi Z, Moses O, Nemcovsky C, Kozlovsky A. Guided periodontal regeneration using bilayered collagen membranes and bovine bone mineral in fenestration defects in the canine. Int J Periodontics Restorative Dent 2005 25:509-518.
54. Nomura T, Katz JL, Powers MP, Saito C. Evaluation of the micro- mechanical elastic properties of potential bone-grafting materials. J Biomed Mater Res B Appl Biomater 2005;73:29-34.