Synthesis of cross-linked carboxyl poly(glycerol methacrylate) and its application for the controlled release of doxorubicin

European Journal of Pharmaceutical Sciences

Volumn 47, Issue 3, 2012, Pages 556-563

  Gu, Wenxing ^a   Ma, Yanan ^a   Zhu, Chuyu ^a   Chen, Baoquan ^a   Ma, Jianbiao ^a   Gao, Hui ^a  

^a TIANJIN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Cross linking; DOX release; pH responsive; Poly(glycerol methacrylate)

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOXYL POLY(GLYCEROL METHACRYLATE); DOXORUBICIN; DRUG CARRIER; HEXAMETHYLENE DIISOCYANATE; NANOPARTICLE; POLYMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; CROSS LINKING; DRUG RELEASE; ENCAPSULATION; GEL PERMEATION CHROMATOGRAPHY; MOLECULAR WEIGHT; MOUSE; NANOENCAPSULATION; NONHUMAN; PH; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL SURVIVAL; CROSS-LINKING REAGENTS; CYANATES; DELAYED-ACTION PREPARATIONS; DOXORUBICIN; DRUG CARRIERS; METHACRYLATES; MICE; NANOPARTICLES; NIH 3T3 CELLS; POLYMERS;

EID: 84865440553     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.07.009     Document Type: Article

References (32)

1. A. Blencowe, J.F. Tang, T.K. Goh, and G.G. Qiao Core cross-linked star polymers via controlled radical polymerisation Polymer 50 2009 5 32
2. J. Ding, L. Wang, H.J. Yu, J. Huo, Q.Q. Liu, and A.G. Xiao Controllable formation of nanorods through electrostatic-assisted assembly of star poly (methacrylic acid) induced by surfactants J. Hys. Chem. C. 113 2009 3471 3477
3. E. Fleige, M.A. Quadir, and R. Haag Stimuli-responsive polymeric nanocarriers for the controlled transport of active compounds: concepts and applications Adv. Drug Delivery Rev. 64 2012 866 884
4. G. Fundueanu, M. Constantin, and P. Ascenzi Preparation and characterization of pH- and temperature-sensitive pollutant microspheres for controlled release of drugs Biomaterials 29 2008 2767 2775
5. H. Gao, M.-C. Jones, P. Tewari, M.R. Chen, R.E. Prudhomme, and J.-C. Leroux Star-shaped alkylated poly(glycerol methacrylate) reverse micelles: synthesis and evaluation of their solubilizing properties Dichloromethane J. Polym. Sci. Part A: Polym. Chem. 45 2007 2425 2435
6. H. Gao, M.-C. Jones, J. Chen, R.E. Prud'homme, and J.-C. Leroux Core cross-linked reverse micelles from star-shaped polymers Chem. Mater. 2008 20 2008 3063 3067
7. A.A. Ghahremankhani, F. Dorkoosh, and R. Dinarvand PLGA-PEG-PLGA tri-block copolymers as an in situ gel forming system for calcitonin delivery Polym. Bull. 59 2007 637 646
8. T. Gong, and C.C. Wang Preparation of highly cross-linked monodispersed functional polystyrene particles by utilizing the delayed addition method J. Mater. Sci. 43 2008 1926 1932
9. J. Groll, Z. Ademovic, T. Ameringer, D. Klee, and M. Moeller Comparison of coatings from reactive star shaped PEG-stat-PPG prepolymers and grafted linear PEG for biological and medical applications Biomacromolecules 6 2005 956 962
10. D. Horak Magnetic poly (glycidyl methacrylate) microspheres by dispersion polymerization J. Polym. Sci. Pol. Chem. 39 2001 3707 3715
11. S. Jukka, K. Harri, H. Risto, and M. Minna Synthesis of novel chain extended and crosslinked poly-lactones for tissue regeneration and controlled release applications Stud. Mechanobiol Tissue Eng. Biomater. 8 2011 409 438
12. J. Kost, and R. Langer Responsive polymeric delivery systems Adv. Drug Delivery Rev. 46 2001 125 148
13. A. Lavasanifar, J. Samuel, and G.S. Kwon Poly(ethyleneoxide) block poly(L-amino acid) micelles for drug delivery Adv. Drug Delivery. Rev. 54 2002 169 190
14. Y.Q. Li, and Y.H. Bae Polymer architecture and drug delivery Pharmacol. Res. 23 2006 1 30
15. J. Lidia, A. Balas, J.T. Haponiuk, G. Nowaczyk, and S. Jurga Thermal and dynamic mechanical analysis of cross-linked poly (Esterurethanes) J. Therm. Anal. Calorimetry 2 2007 419 423
16. X.Y. Lu, H. Gao, C. Li, Y.W. Yang, Y.N. Wang, Y.G. Fan, G.L. Wu, and J.B. Ma Polyelectrolyte complex nanoparticles of amino poly(glycerol methacrylate)s and insulin Int. J. Pharm. 423 2012 195 201
17. Y.N. Ma, H. Gao, W.X. Gu, Y.N. Wang, Y.G. Fan, G.L. Wu, and J.B. Ma Carboxylated poly(glycerol methacrylate)s for doxorubicin delivery Eur. J. Pharm. Sci. 45 2012 65 72
18. G.R. Newkome, Z. Yao, G.R. Baker, and V.K. Gupta Cascade molecules: a new approach to micelles. a [27]- arborol J. Org. Chem. 50 1985 2003 2004
19. R.K. O'Reilly, J. HawkerC, and K.L. Wooley Cross-linked block copolymer micelles: functional nanostructures of great potential and versatility Chem. Soc. Rev. 35 2006 1068 1083
20. M. Ouchi, T. Terashima, and M. Sawamoto Transition metal-catalyzed living radical polymerization: toward perfection in catalysis and precision polymer synthesis Chem. Rev. 109 2009 4963 5050
21. S. Qiu, H. Huang, X.H. Dai, W. Zhou, and C.M. Dong Star-shaped polypeptide glycopolymer bio-hybrids: synthesis, self-assembly, biomolecular recognition, and controlled drug release behavior J. Polym. Sci. A.: Polym. Chem. 47 2009 2009 2023
22. E.S. Read, and S.P. Armes Recent advances in shell cross-linked micelles Chem. Commun. 29 2007 3021 3035
23. M.V. Risbud, A.A. Hardikar, S.V. Bhat, and R.R. Bhonde PH-sensitive freeze-dried chitosan-polyvinyl pyrrolidone hydrogels as controlled release system for antibiotic delivery J. Controlled Release 68 2000 23 30
24. D. Schmaljohann Thermo- and pH-responsive polymers in drug delivery Adv. Drug Delivery Rev. 58 2006 1655 1670
25. Y. Sun, and W.Q. Liu Synthesis and properties of cross-linkable block copolymer end-capped with 2,2,3,4,4,4-hexafluorobutyl methacrylate J. Polym. Res. 19 2012 9768
26. T. Terashima, M. Ouchi, T. Ando, and M. Sawamoto Thermoregulated phase-transfer catalysis via PEG-armed Ru (II)-bearing microgel core star polymers: efficient and reusable Ru (II) catalysts for aqueous transfer hydrogenation of ketones J. Polym. Sci. A: Polym. Chem. 48 2010 373 379
27. P.D. Thornton, R.J. Mart, and R.V. Ulijin Enzyme-responsive polymer hydrogel particles for controlled release Adv. Mater. 19 2007 1252 1256
28. K.B. Thurmond, T. Kowalewski, and K.L. Wooley The preparation of shell-cross-linked small particles J. Am. Chem. Soc. 118 1996 7239 7240
29. D.A. Tomalia, and H.A. Baker A new class of polymers: starburst-dendritic macromolecules Polym. J. 17 1985 117 132
30. Xiao, L.; Zhu, B.K.; 2006. Reaction and characterization of crosslinking hyper-branched poly(amine-ester) with succine snhydride. J. East China Uni. Sci. Tech. (Nat. Sci. Ed.) 32, 1164-1168.
31. W. Xiong, X. Gao, Y.B. Zhao, H.B. Xu, and X.L. Yang The dual temperature pH-sensitive multiphase behavior of poly(N-isopropylacrylamide-co-acrylic acid) microgels for potential application in situ gelling system Colloids Surf. B 84 2011 103 110
32. Y.-W. Yang Towards biocompatible nanovalves based on mesoporous silica nanoparticles Med. Chem. Commun. 2 2011 1033 1049