Preparation and characterization of pH- and temperature-sensitive pullulan microspheres for controlled release of drugs

Biomaterials

Volumn 29, Issue 18, 2008, Pages 2767-2775

  Fundueanu, Gheorghe ^a,b   Constantin, Marieta ^b   Ascenzi, Paolo ^c,d  

^a UNIVERSITY OF FERRARA   (Italy)

^b PETRU PONI INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Romania)

^c ROMA TRE UNIVERSITY   (Italy)

^d NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

Author keywords

Drug delivery; Intelligent microspheres; Lower critical solution temperature; pH thermo responsive copolymers; Pullulan

Indexed keywords

BIOCOMPATIBILITY; BIODEGRADABLE POLYMERS; CONTROLLED DRUG DELIVERY; HYDROPHILICITY; PH; PHASE TRANSITIONS; SWELLING;

INTELLIGENT MICROSPHERES; LOWER CRITICAL SOLUTION TEMPERATURE; PH/THERMO-RESPONSIVE COPOLYMERS;

MICROSPHERES;

EPICHLOROHYDRIN; LYSOZYME; MICROSPHERE; POLY(N ISOPROPYLACRYLAMIDE); PULLULAN; SUCCINIC ANHYDRIDE;

ARTICLE; CONTROLLED DRUG RELEASE; CROSS LINKING; DRUG DELIVERY SYSTEM; HEAT SENSITIVITY; IONIZATION; MOLECULAR MODEL; PH; PHASE TRANSITION; PRIORITY JOURNAL; PROTON TRANSPORT; TEMPERATURE SENSITIVITY;

DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; GLUCANS; HYDROGEN-ION CONCENTRATION; KINETICS; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS; TEMPERATURE;

EID: 42049083157     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.03.025     Document Type: Article

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