Kinetic modelling of GlmU reactions - prioritization of reaction for therapeutic application

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Singh, Vivek K ^a   Das, Kaveri ^a   Seshadri, Kothandaraman ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; BACTERIAL ENZYME; ENZYME INHIBITOR; GLUCOSAMINE 1 PHOSPHATE N ACETYLTRANSFERASE; HEXOSE 1 PHOSPHATE URIDYLYLTRANSFERASE; N ACETYLGLUCOSAMINE 1 PHOSPHATE URIDYLYTRANSFERASE; PEPTIDOGLYCAN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOLOGICAL FUNCTIONS; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL LEVEL; CELL SURVIVAL; CHEMICAL PARAMETERS; CHEMICAL REACTION KINETICS; CONCENTRATION RESPONSE; ENZYME ACTIVITY; ENZYME INHIBITION; ESCHERICHIA COLI; ESSENTIAL GENE; GENETIC ANALYSIS; HIGH THROUGHPUT SCREENING; IN VIVO STUDY; NONHUMAN; PROTEIN TARGETING;

ACETYLGLUCOSAMINE; ACETYLTRANSFERASES; BIOCATALYSIS; COMPUTATIONAL BIOLOGY; DRUG RESISTANCE, BACTERIAL; ENZYME INHIBITORS; KINETICS; MODELS, CHEMICAL; MYCOBACTERIUM TUBERCULOSIS;

EID: 84865437024     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043969     Document Type: Article

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