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Volumn 209, Issue , 2012, Pages 126-137

The influence of customized geometries and process parameters on nanoemulsion and solid lipid nanoparticle production in microsystems

Author keywords

Customized micro fluidics systems; Droplet break up efficiency; High pressure homogenization; Nanoemulsion; Solid lipid nanoparticles

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; DESIGN PARAMETERS; DROPLET BREAKUP; ELEVATED TEMPERATURE; HIGH PRESSURE HOMOGENIZATION; HIGH QUALITY; NANOEMULSION; PHARMACEUTICAL APPLICATIONS; PROCESS PARAMETERS; SOLID LIPID NANOPARTICLE (SLN); STRAIGHT CHANNEL; Z-CHANNELS;

EID: 84865408356     PISSN: 13858947     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cej.2012.07.115     Document Type: Article
Times cited : (27)

References (32)
  • 1
    • 2342619540 scopus 로고    scopus 로고
    • High-pressure homogenization as a process for emulsion formation
    • Schultz S., Wagner G., Urban K., Ulrich J. High-pressure homogenization as a process for emulsion formation. Chem. Eng. Technol. 2004, 27:361-368.
    • (2004) Chem. Eng. Technol. , vol.27 , pp. 361-368
    • Schultz, S.1    Wagner, G.2    Urban, K.3    Ulrich, J.4
  • 3
    • 67650035441 scopus 로고    scopus 로고
    • Structural design principles for delivery of bioactive components in nutraceuticals and functional foods
    • McClements D.J., Decker E.A., Park Y., Weiss J. Structural design principles for delivery of bioactive components in nutraceuticals and functional foods. Crit. Rev. Food Sci. Nutr. 2009, 49:577-606.
    • (2009) Crit. Rev. Food Sci. Nutr. , vol.49 , pp. 577-606
    • McClements, D.J.1    Decker, E.A.2    Park, Y.3    Weiss, J.4
  • 5
    • 59649097447 scopus 로고    scopus 로고
    • Lipid nanoparticles for parenteral delivery of actives
    • Joshi M.D., Müller R.H. Lipid nanoparticles for parenteral delivery of actives. Eur. J. Pharm. Biopharm. 2009, 71:161-172.
    • (2009) Eur. J. Pharm. Biopharm. , vol.71 , pp. 161-172
    • Joshi, M.D.1    Müller, R.H.2
  • 6
    • 80054804587 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: an oral bioavailability enhancer vehicle
    • Harde H., Das M., Jain S. Solid lipid nanoparticles: an oral bioavailability enhancer vehicle. Expert Opin. Drug Delivery 2011, 8:1407-1424.
    • (2011) Expert Opin. Drug Delivery , vol.8 , pp. 1407-1424
    • Harde, H.1    Das, M.2    Jain, S.3
  • 7
    • 45849118730 scopus 로고    scopus 로고
    • Lipid nanoparticles (SLN®, NLC®) for cutaneous drug delivery: structure, protection and skin effects
    • Souto E.B., Almeida A.J., Müller R.H. Lipid nanoparticles (SLN®, NLC®) for cutaneous drug delivery: structure, protection and skin effects. J. Biomed. Nanotechnol. 2007, 3:317-331.
    • (2007) J. Biomed. Nanotechnol. , vol.3 , pp. 317-331
    • Souto, E.B.1    Almeida, A.J.2    Müller, R.H.3
  • 8
    • 57849099131 scopus 로고    scopus 로고
    • Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products
    • Pardeike J., Hommoss A., Müller R.H. Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products. Int. J. Pharm. 2009, 366:170-184.
    • (2009) Int. J. Pharm. , vol.366 , pp. 170-184
    • Pardeike, J.1    Hommoss, A.2    Müller, R.H.3
  • 9
    • 33748318061 scopus 로고    scopus 로고
    • Sun protection enhancement of titanium dioxide crystals by the use of carnauba wax nanoparticles: the synergistic interaction between organic and inorganic sunscreens at nanoscale
    • Villalobos-Hernandez J.R., Müller-Goymann C.C. Sun protection enhancement of titanium dioxide crystals by the use of carnauba wax nanoparticles: the synergistic interaction between organic and inorganic sunscreens at nanoscale. Int. J. Pharm. 2006, 322:161-170.
    • (2006) Int. J. Pharm. , vol.322 , pp. 161-170
    • Villalobos-Hernandez, J.R.1    Müller-Goymann, C.C.2
  • 10
    • 36248939564 scopus 로고    scopus 로고
    • In vitro erythemal UV-A protection factors of inorganic sunscreens distributed in aqueous media using carnauba wax-decyl oleate nanoparticles
    • Villalobos-Hernandez J.R., Müller-Goymann C.C. In vitro erythemal UV-A protection factors of inorganic sunscreens distributed in aqueous media using carnauba wax-decyl oleate nanoparticles. Eur. J. Pharm. Biopharm. 2007, 65:122-125.
    • (2007) Eur. J. Pharm. Biopharm. , vol.65 , pp. 122-125
    • Villalobos-Hernandez, J.R.1    Müller-Goymann, C.C.2
  • 11
    • 0037677616 scopus 로고    scopus 로고
    • Characterization of solidified reverse micellar solutions (SRMS) and production development of SRMS-based nanosuspensions
    • Friedrich I., Müller-Goymann C. Characterization of solidified reverse micellar solutions (SRMS) and production development of SRMS-based nanosuspensions. Eur. J. Pharm. Biopharm. 2003, 56:111-119.
    • (2003) Eur. J. Pharm. Biopharm. , vol.56 , pp. 111-119
    • Friedrich, I.1    Müller-Goymann, C.2
  • 12
    • 27644538545 scopus 로고    scopus 로고
    • Drug release and permeation studies of nanosuspensions based on solidified reverse micellar solutions (SRMS)
    • Friedrich I., Reichl S., Müller-Goymann C. Drug release and permeation studies of nanosuspensions based on solidified reverse micellar solutions (SRMS). Int. J. Pharm. 2005, 305:167-175.
    • (2005) Int. J. Pharm. , vol.305 , pp. 167-175
    • Friedrich, I.1    Reichl, S.2    Müller-Goymann, C.3
  • 15
    • 0035946615 scopus 로고    scopus 로고
    • Solid lipid nanoparticles production, characterization and applications
    • Mehnert W., Mäder K. Solid lipid nanoparticles production, characterization and applications. Adv. Drug Delivery Rev. 2001, 47:165-196.
    • (2001) Adv. Drug Delivery Rev. , vol.47 , pp. 165-196
    • Mehnert, W.1    Mäder, K.2
  • 16
    • 0024381166 scopus 로고
    • Design and characterization of a submicronized o/w emulsion of diazepam for parenteral use
    • Levy M., Benita S. Design and characterization of a submicronized o/w emulsion of diazepam for parenteral use. Int. J. Pharm. 1989, 54:103-112.
    • (1989) Int. J. Pharm. , vol.54 , pp. 103-112
    • Levy, M.1    Benita, S.2
  • 17
    • 2342643460 scopus 로고    scopus 로고
    • Emulsification: more than just comminution: emulgieren: mehr als nur zerkleinern
    • Schuchmann H.P., Danner T. Emulsification: more than just comminution: emulgieren: mehr als nur zerkleinern. Chem. Ing. Tech. 2004, 76:364-375.
    • (2004) Chem. Ing. Tech. , vol.76 , pp. 364-375
    • Schuchmann, H.P.1    Danner, T.2
  • 18
    • 79955794727 scopus 로고    scopus 로고
    • Preparation, characterization and biocompatibility studies on risperidone-loaded solid lipid nanoparticles (SLN): high pressure homogenization versus ultrasound
    • Silva A., González-Mira E., García M., Egea M., Fonseca J., Silva R., Santos D., Souto E., Ferreira D. Preparation, characterization and biocompatibility studies on risperidone-loaded solid lipid nanoparticles (SLN): high pressure homogenization versus ultrasound. Colloids Surf. B 2011, 86:158-165.
    • (2011) Colloids Surf. B , vol.86 , pp. 158-165
    • Silva, A.1    González-Mira, E.2    García, M.3    Egea, M.4    Fonseca, J.5    Silva, R.6    Santos, D.7    Souto, E.8    Ferreira, D.9
  • 19
    • 0023946332 scopus 로고
    • The production of parenteral feeding emulsions by microfluidizer
    • Washington C., Davis S.S. The production of parenteral feeding emulsions by microfluidizer. Int. J. Pharm. 1988, 44:169-176.
    • (1988) Int. J. Pharm. , vol.44 , pp. 169-176
    • Washington, C.1    Davis, S.S.2
  • 20
    • 84874331778 scopus 로고    scopus 로고
    • Development of a dispersion micro-element for pharmaceutical screening applications: material and fabrication
    • MST Kongress
    • C. Lesche, S. Büttgenbach, Development of a dispersion micro-element for pharmaceutical screening applications: material and fabrication, MST Kongress (2009).
    • (2009)
    • Lesche, C.1    Büttgenbach, S.2
  • 21
    • 84864614291 scopus 로고    scopus 로고
    • Novel 3D manufacturing method combining microelectrial discharge machining and electrochemical polishing
    • Richter C., Krah T., Büttgenbach S. Novel 3D manufacturing method combining microelectrial discharge machining and electrochemical polishing. Microsyst. Technol. 2012.
    • (2012) Microsyst. Technol.
    • Richter, C.1    Krah, T.2    Büttgenbach, S.3
  • 23
    • 84874329074 scopus 로고    scopus 로고
    • Effect of emulsifier type and disruption chamber geometry on the fabrication of food nanoemulsions by high pressure homogenization
    • 111104124945002.
    • F. Donsì, M. Sessa, G. Ferrari, Effect of emulsifier type and disruption chamber geometry on the fabrication of food nanoemulsions by high pressure homogenization, Ind. Eng. Chem. Res. (2011) 111104124945002.
    • (2011) Ind. Eng. Chem. Res.
    • Donsì, F.1    Sessa, M.2    Ferrari, G.3
  • 24
    • 14544277961 scopus 로고    scopus 로고
    • Emulsion processing-from single-drop deformation to design of complex processes and products
    • Windhab E., Dressler M., Feigl K., Fischer P., Megias-Alguacil D. Emulsion processing-from single-drop deformation to design of complex processes and products. Chem. Eng. Sci. 2005, 60:2101-2113.
    • (2005) Chem. Eng. Sci. , vol.60 , pp. 2101-2113
    • Windhab, E.1    Dressler, M.2    Feigl, K.3    Fischer, P.4    Megias-Alguacil, D.5
  • 25
    • 57749084381 scopus 로고    scopus 로고
    • Studying the effects of adsorption, recoalescence and fragmentation in a high pressure homogenizer using a dynamic simulation model
    • Håkansson A., Trägårdh C., Bergenståhl B. Studying the effects of adsorption, recoalescence and fragmentation in a high pressure homogenizer using a dynamic simulation model. Food Hydrocolloids 2009, 23:1177-1183.
    • (2009) Food Hydrocolloids , vol.23 , pp. 1177-1183
    • Håkansson, A.1    Trägårdh, C.2    Bergenståhl, B.3
  • 26
    • 0033370405 scopus 로고    scopus 로고
    • Investigations on the role of surfactants in mechanical emulsification using a high-pressure homogenizer with an orifice valve
    • Brösel S., Schubert H. Investigations on the role of surfactants in mechanical emulsification using a high-pressure homogenizer with an orifice valve. Chem. Eng. Process. 1999, 38:533-540.
    • (1999) Chem. Eng. Process. , vol.38 , pp. 533-540
    • Brösel, S.1    Schubert, H.2
  • 27
    • 0035281869 scopus 로고    scopus 로고
    • Evaluation of a new high-pressure dispersion unit (HPN) for emulsification
    • Kolb G., Viardot K., Wagner G., Ulrich J. Evaluation of a new high-pressure dispersion unit (HPN) for emulsification. Chem. Eng. Technol. 2001, 24:293-296.
    • (2001) Chem. Eng. Technol. , vol.24 , pp. 293-296
    • Kolb, G.1    Viardot, K.2    Wagner, G.3    Ulrich, J.4
  • 28
    • 0037487242 scopus 로고    scopus 로고
    • Production of emulsions in high-pressure homogenizers - Part II: influence of cavitation on droplet breakup
    • Freudig B., Tesch S., Schubert H. Production of emulsions in high-pressure homogenizers - Part II: influence of cavitation on droplet breakup. Chem. Eng. Technol. 2003, 26:266-270.
    • (2003) Chem. Eng. Technol. , vol.26 , pp. 266-270
    • Freudig, B.1    Tesch, S.2    Schubert, H.3
  • 30
    • 29244486455 scopus 로고    scopus 로고
    • Structural investigations on lipid nanoparticles containing high amounts of lecithin
    • Schubert M.A., Harms M., Müller-Goymann C.C. Structural investigations on lipid nanoparticles containing high amounts of lecithin. Eur. J. Pharm. Sci. 2006, 27:226-236.
    • (2006) Eur. J. Pharm. Sci. , vol.27 , pp. 226-236
    • Schubert, M.A.1    Harms, M.2    Müller-Goymann, C.C.3
  • 31
    • 1842503102 scopus 로고    scopus 로고
    • Investigation on particle self-assembly in solid lipid-based colloidal drug carrier systems
    • Illing A., Unruh T., Koch M.H.J. Investigation on particle self-assembly in solid lipid-based colloidal drug carrier systems. Pharm. Res. 2004, 21:592-597.
    • (2004) Pharm. Res. , vol.21 , pp. 592-597
    • Illing, A.1    Unruh, T.2    Koch, M.H.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.