The NF-κB-like factor DIF could explain some positive effects of a mild stress on longevity, behavioral aging, and resistance to strong stresses in Drosophila melanogaster

Biogerontology

Volumn 13, Issue 4, 2012, Pages 445-455

  Le Bourg, Éric ^a   Malod, Kévin ^a   Massou, Isabelle ^a  

^a Université Paul Sabatier   (France)

Author keywords

Aging; Behavioral aging; Cold stress; DIF transcription factor; Drosophila melanogaster; Fungal infection; Heat stress; Hormesis; Longevity; Mild stress

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DIF; UNCLASSIFIED DRUG;

ARTICLE; COLD STRESS; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; FEMALE; HEAT STRESS; HORMESIS; INNATE IMMUNITY; LONGEVITY; MALE; MYCOSIS; NONHUMAN; PRIORITY JOURNAL; STRESS;

AGING; ANIMALS; BEHAVIOR, ANIMAL; COLD TEMPERATURE; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; LONGEVITY; MALE; MUTATION; SEX FACTORS; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS;

EID: 84865390133     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-012-9389-0     Document Type: Article

References (39)

1. Bauer M, Katzenberger JD, Hamm AC, Bonaus M, Zinke I, Jaekel J, Pankratz MJ (2006) Purine and folate metabolism as a potential target of sex-specific nutrient allocation in Drosophila and its implication for lifespan-reproduction tradeoff. Physiol Genomics 25:393-404 (Pubitemid 43764762)
2. Becker T, Loch G, Beyer M, Zinke I, Aschenbrenner AC, Carrera P, Inhester T, Schultze JL, Hoch M (2010) FOXO-dependent regulation of innate immune homeostasis. Nature 463:369-373
3. Carter ME, Brunet A (2007) FOXO transcription factors. Curr Biol 17:R113-R114 (Pubitemid 46241884)
4. Chen J, Senturk D, Wang JL, Müller HG, Carey JR, Caswell H, Caswell-Chen EP (2007) A demographic analysis of the fitness cost of extended longevity in Caenorhabditis ele-gans. J Gerontol A Biol Sci Med Sci 62:126-135 (Pubitemid 47065736)
5. Colinet H, Lee SF, Hoffmann A (2010) Temporal expression of heat shock genes during cold stress and recovery from chill coma in adult Drosophila melanogaster. FEBS J 277:174-185
6. Hasegawa Y, Saito T, Ogihara T, Ishigaki Y, Yamada T, Imai J, Uno K, Gao J, Kaneko K, Shimosawa T, Asano T, Fujita T, Oka Y, Katagiri H (2012) Blockade of the nuclear factor-jB pathway in the endothelium prevents insulin resistance and prolongs lifespans. Circulation 125:1122-1133
7. Hercus MJ, Loeschcke V, Rattan SIS (2003) Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress. Biogerontology 4:149-156 (Pubitemid 36818011)
8. Jenkins NL, McColl G, Lithgow GJ (2004) Fitness cost of extended lifespan in Caenorhabdidtis elegans. Proc Biol Sci 271:2523-2526
9. Kristensen TN, Sørensen JG, Loeschcke V (2003) Mild heat stress at a young age in Drosophila melanogaster leads to increased Hsp70 synthesis after stress exposure later in life. J Genet 82:89-94 (Pubitemid 38650947)
10. Le Bourg E (2007) Hormetic effects of repeated exposures to cold at young age on longevity, aging and resistance to heat or cold shocks in Drosophila melanogaster. Biogerontol-ogy 8:431-444 (Pubitemid 47054800)
11. Le Bourg E (2008) Three mild stresses known to increase longevity in Drosophila melanogaster flies do not increase resistance to oxidative stress. Am J Pharmacol Toxicol 3:134-140
12. Le Bourg E (2009a) Hormesis, aging and longevity. Biochim Biophys Acta 1790:1030-1039
13. Le Bourg E (2009b) Mild stress and life extension in Drosophila melanogaster. In: Sell C, Lorenzini A, Brown-Borg HM (eds) Life-span extension, single-cell organisms to man. Humana Press, Dordrecht, pp 75-88
14. Le Bourg E (2010) Combined effects of suppressing live yeast and of a cold pretreatment on longevity, aging and resistance to several stresses in Drosophila melanogaster. Bi-ogerontology 11:245-254
15. Le Bourg E (2011a) A cold stress applied at various ages can increase resistance to heat and fungal infection in aged Drosophila melanogaster flies. Biogerontology 12:185-193
16. Le Bourg E (2011b) The NF-kB like factor DIF has weaker effects on Drosophila melanogaster immune defenses than previously thought. J Comp Physiol B 181:741-750
17. Le Bourg E (2012) Combined effects of two mild stresses (cold and hypergravity) on longevity, behavioral aging, and resistance to severe stresses in Drosophila melanogaster. Biogerontology 13:313-328
18. Le Bourg E, Fournier D (2004) Is lifespan extension accompanied by improved antioxidant defences? A study of superoxide dismutase and catalase in Drosophila melano-gaster flies that lived in hypergravity at young age. Bio-gerontology 5:261-266 (Pubitemid 39157991)
19. Le Bourg E, Massou I, Gobert V (2009) Cold stress increases resistance to fungal infection throughout life in Drosophila melanogaster. Biogerontology 10:613-625
20. Lemâitre B, Hoffmann J (2007) The host defense of Drosophila melanogaster. Annu Rev Immunol 25:697-743 (Pubitemid 46697922)
21. Lemâitre B, Reichhart JM, Hoffmann JA (1997) Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proc Natl Acad Sci USA 94:14614-14619 (Pubitemid 28041422)
22. Marden JH, Rogina B, Montooth KL, Helfand SL (2003) Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies. Proc Natl Acad Sci USA 100:3369-3373 (Pubitemid 36356590)
23. Martinelli C, Reichhart JM (2005) Evolution and integration of innate immune systems from fruit flies to man: lessons and questions. J Endotoxin Res 11:243-248 (Pubitemid 41358860)
24. Mattson MP, Calabrese EJ (eds) (2010) Hormesis: a revolution in biology, toxicology and medicine. Springer, Dordrecht
25. Moskalev A, Shaposhnikov M (2011) Pharmacological inhibition of NF-jB prolongs lifespan of Drosophila melano-gaster. Aging (Albany NY) 3:391-394
26. Moskalev A, Shaposhnikov M, Turysheva E (2009) Life span alteration after irradiation in Drosophila melanogaster strains with mutations of Hsf and Hsps. Biogerontology 10:3-11
27. Moskalev AA, Plyusnina EN, Shaposhnikov MV (2011) Radiation hormesis and radioadaptive response in Drosophila melanogaster flies with different genetic backgrounds: the role of cellular stress-resistance mechanisms. Biogeron-tology 12:253-263
28. Roberts JR, Rowe PA, Demaine AG (2002) Activation of NF-jB and MAP kinase cascades by hypothermic stress in endothelial cells. Cryobiology 44:161-169 (Pubitemid 36132368)
29. Rutschmann S, Jung AC, Hetru C, Reichhart JM, Hoffmann JA, Ferrandon D (2000) The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Dro-sophila. Immunity 12:569-580
30. Salminen A, Huuskonen J, Ojala J, Kauppinen A, Kaarniranta K, Suuronen T (2008) Activation of innate immunity system during aging: nF-jB signaling is the molecular culprit of inflamm-aging. Ageing Res Rev 7:83-105 (Pubitemid 351418294)
31. Sarup P, Loeschcke V (2011) Life extension and the position of the hormetic zone depends on sex and genetic background in Drosophila melanogaster. Biogerontology 12:109-117
32. Selkirk GA, McLellan TM, Wright HE, Rhind SG (2008) Mild endotoxemia, NF-jB translocation, and cytokine increase during exertional heat stress in trained and untrained individuals. Am J Physiol Regul Integr Comp Physiol 295:R611-R623
33. Seong KM, Kim CS, Seo SW, Jeon HY, Lee BS, Nam SY, Yang KH, Kim JY, Kim CS, Min KJ, Jin YW (2011) Genome-wide analysis of low-dose irradiated male Drosophila melanogaster with extended longevity. Biogerontology 12:93-107
34. Sinclair BJ, Gibbs AG, Roberts SP (2007) Gene transcription during exposure to, and recovery from, cold and desiccation stress in Drosophila melanogaster. Insect Mol Biol 16:435-443 (Pubitemid 47094272)
35. Sørensen JG, Kristensen TN, Kristensen KV, Loeschcke V (2007) Sex specific effects of heat induced hormesis in Hsf-deficient Drosophila melanogaster. Exp Gerontol 42:11231129
36. Vaiserman AM, Koshel NM, Litoshenko AY, Mozzhukhina TG, Voitenko VP (2003) Effect of X-irradiation in early ontogenesis on the longevity and amount of S1 nuclease-sensitive DNA sites in adult Drosophila melanogaster. Biogerontology 4:9-14 (Pubitemid 36372271)
37. Van Voorhies WA, Curtsinger JW, Rose MR (2006) Do longevity mutants always show trade-offs? Exp Gerontol 41:1055-1058 (Pubitemid 44821683)
38. Walker DW, McColl G, Jenkins NL, Harris J, Lithgow GJ (2000) Evolution of lifespan in C. elegans. Nature 405:296-297 (Pubitemid 30337051)
39. Zhang J, Marshall KE, Westwood JT, Clark MS, Sinclair BJ (2011) Divergent transcriptomic responses to repeated and single cold exposures in Drosophila melanogaster. J Exp Biol 214:4021-4029