Preparation of ibuprofen/EC-PVP sustained-release composite particles by supercritical CO2 anti-solvent technology

Yaoxue Xuebao

Volumn 47, Issue 6, 2012, Pages 791-796

  Cai, Jin Yuan ^a   Huang, De Chun ^a   Wang, Zhi Xiang ^a   Dang, Bei Lei ^a   Wang, Qiu Ling ^a   Su, Xin Guang ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Composite particle; Ibuprofen; In vitro releasing; Supercritical CO2 anti solvent technology; Sustained release

Indexed keywords

CARBON DIOXIDE; ETHYL CELLULOSE; IBUPROFEN; IBUPROFEN ETHYL CELLULOSE POLYVINYLPYRROLIDONE; POVIDONE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL COMPOSITION; COMPLEX FORMATION; COMPOSITE PARTICLE; CONCENTRATION RESPONSE; CRYSTALLIZATION; CRYSTALLIZATION PRESSURE; CRYSTALLIZATION TEMPERATURE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG SOLUBILITY; DRUG SYNTHESIS; ELECTRON MICROSCOPY; ENCAPSULATION; ENCAPSULATION EFFICIENCY; IN VITRO STUDY; INFRARED SPECTROSCOPY; MEDICAL TECHNOLOGY; PARAMETERS; PARTICLE SIZE; PARTICLE SIZE DISTRIBUTION; PROCESS OPTIMIZATION; SUPERCRITICAL CARBON DIOXIDE ANTI SOLVENT TECHNOLOGY; SUSTAINED DRUG RELEASE; SUSTAINED RELEASE FORMULATION; VELOCITY;

CALORIMETRY, DIFFERENTIAL SCANNING; CARBON DIOXIDE; CELLULOSE; CRYSTALLIZATION; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG COMPOUNDING; IBUPROFEN; MICROSCOPY, CONFOCAL; PARTICLE SIZE; POVIDONE; SOLUBILITY; SPECTROPHOTOMETRY, INFRARED; TECHNOLOGY, PHARMACEUTICAL;

EID: 84865346361     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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