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Volumn 50, Issue 3, 2012, Pages 311-318

Deviated nasal septum hinders intranasal sprays: A computer simulation study

Author keywords

Computational fluid dynamics; Inspiratory airflow; Intranasal spray; Particle deposition; Septal deviation

Indexed keywords

NOSE SPRAY;

EID: 84865336992     PISSN: 03000729     EISSN: None     Source Type: Journal    
DOI: 10.4193/rhin12.053     Document Type: Article
Times cited : (38)

References (39)
  • 1
    • 0036896831 scopus 로고    scopus 로고
    • Nasal drug delivery: New develop1.-ments and strategies
    • Illum L. Nasal drug delivery: new develop1.-ments and strategies. Drug Discovery Today 2002; 7:1184-1189.
    • (2002) Drug Discovery Today , vol.7 , pp. 1184-1189
    • Illum, L.1
  • 2
    • 34047227104 scopus 로고    scopus 로고
    • Characterization of deposition from nasal spray devices using a computational fluid dynamics model of the human nasal passages
    • Kimbell JS, Segal RA, Asgharian Bet al. Characterization of deposition from nasal spray devices using a computational fluid dynamics model of the human nasal passages. J Aerosol Med 2007; 20:59-74.
    • (2007) J Aerosol Med , vol.20 , pp. 59-74
    • Kimbell, J.S.1    Segal, R.A.2    Asgharian, B.3
  • 3
    • 84865324574 scopus 로고    scopus 로고
    • Effects of Anatomy and Particle Size on Nasal Sprays and Nebulizers
    • Nov 2. [Epub ahead of print]
    • Frank DO, Kimbell JS, Pawar S, Rhee JS. Effects of Anatomy and Particle Size on Nasal Sprays and Nebulizers. Otolaryngol Head Neck Surg. 2011 Nov 2. [Epub ahead of print].
    • (2011) Otolaryngol Head Neck Surg.
    • Frank, D.O.1    Kimbell, J.S.2    Pawar, S.3    Rhee, J.S.4
  • 4
    • 0032754596 scopus 로고    scopus 로고
    • Comparison of nasal deposition and clearance of aerosol generated by nebulizer and an aqueous spray pump
    • Suman JD, Laube BL, Dalby R. Comparison of nasal deposition and clearance of aerosol generated by nebulizer and an aqueous spray pump. Pharmaceutical Res. 1999; 16: 1648-1652.
    • (1999) Pharmaceutical Res. , vol.16 , pp. 1648-1652
    • Suman, J.D.1    Laube, B.L.2    Dalby, R.3
  • 5
    • 84864332253 scopus 로고    scopus 로고
    • Nasal Deposition and Clearance in Man: Comparison of a Bidirectional Powder Device and a Traditional Liquid Spray Pump
    • Jan 17. [Epub ahead of print]
    • Djupes land PG, Sk ret t ing A. Nasal Deposition and Clearance in Man: Comparison of a Bidirectional Powder Device and a Traditional Liquid Spray Pump. J Aerosol Med Pulm Drug Deliv. 2012. Jan 17. [Epub ahead of print].
    • (2012) J Aerosol Med Pulm Drug Deliv.
    • Djupesland, P.G.1    Skretting, A.2
  • 6
    • 37548998558 scopus 로고    scopus 로고
    • The influence of spray properties on intranasal deposition
    • Foo MY, Cheng Y-S, Su W-C, Donovan MD. The influence of spray properties on intranasal deposition. J Aerosol Med 2007; 20: 495-508.
    • (2007) J Aerosol Med , vol.20 , pp. 495-508
    • Foo, M.Y.1    Cheng, Y-S.2    Su, W-C.3    Donovan, M.D.4
  • 8
    • 33746585786 scopus 로고    scopus 로고
    • Expanding choices in intranasal steroid therapy: Summary of a roundtable meeting
    • Blaiss MS, Benninger MS, Fronmer L, et al. Expanding choices in intranasal steroid therapy: Summary of a roundtable meeting. Allergy Asthma Proc. 2006; 27: 254-264.
    • (2006) Allergy Asthma Proc. , vol.27 , pp. 254-264
    • Blaiss, M.S.1    Benninger, M.S.2    Fronmer, L.3
  • 10
    • 0034885109 scopus 로고    scopus 로고
    • Characterization of nasal spray pumps and deposition pattern in a replica of the human nasal airway
    • Cheng YS, Holmes TD, Gao J et al. Characterization of nasal spray pumps and deposition pattern in a replica of the human nasal airway. J Aerosol Med. 2001; 14: 267-280.
    • (2001) J Aerosol Med. , vol.14 , pp. 267-280
    • Cheng, Y.S.1    Holmes, T.D.2    Gao, J.3
  • 11
    • 0036408844 scopus 로고    scopus 로고
    • A study of intranasal distribution of azelastine hydrochloride aqueous nasal spray with different spray techniques
    • Bateman ND, Whymark AD, Clifton NJ, Woolford TJ. A study of intranasal distribution of azelastine hydrochloride aqueous nasal spray with different spray techniques. Clin Otolaryngol. 2002; 27: 327-330.
    • (2002) Clin Otolaryngol. , vol.27 , pp. 327-330
    • Bateman, N.D.1    Whymark, A.D.2    Clifton, N.J.3    Woolford, T.J.4
  • 12
    • 0034075905 scopus 로고    scopus 로고
    • The relationship between particle deposition in the anterior nasal passage and nasal passage characteristics
    • Kesavan J, Bascom R, Laube B, Swift DL. The relationship between particle deposition in the anterior nasal passage and nasal passage characteristics. J Aerosol Med. 2000; 13: 17-23.
    • (2000) J Aerosol Med. , vol.13 , pp. 17-23
    • Kesavan, J.1    Bascom, R.2    Laube, B.3    Swift, D.L.4
  • 13
    • 33750964875 scopus 로고    scopus 로고
    • Analysis of particle deposition in the turbinate and olfactory regions using a human nasal computational fluid dynamics model
    • Schroeter JD, Kimbell JS, Asgharian B. Analysis of particle deposition in the turbinate and olfactory regions using a human nasal computational fluid dynamics model. J Aerosol Med. 2006; 19: 301-313.
    • (2006) J Aerosol Med. , vol.19 , pp. 301-313
    • Schroeter, J.D.1    Kimbell, J.S.2    Asgharian, B.3
  • 14
    • 75749152943 scopus 로고    scopus 로고
    • Septal deviation and nasal resistance: An investigation using virtual surgery and computational fluid dynamics
    • Garcia GJ, Rhee JS, Senior BA, Kimbell JS. Septal deviation and nasal resistance: an investigation using virtual surgery and computational fluid dynamics. Am J Rhinol Allergy. 2010; 24: e46-53.
    • (2010) Am J Rhinol Allergy. , vol.24
    • Garcia, G.J.1    Rhee, J.S.2    Senior, B.A.3    Kimbell, J.S.4
  • 16
    • 34548442846 scopus 로고    scopus 로고
    • Atrophic rhinitis: A CFD study of air conditioning in the nasal cavity
    • Garcia GJM, Bailie N, Martins DA, Kimbell JS. Atrophic rhinitis: A CFD study of air conditioning in the nasal cavity. J Appl Physiol. 2007; 103: 1082-1092.
    • (2007) J Appl Physiol. , vol.103 , pp. 1082-1092
    • Garcia, G.J.M.1    Bailie, N.2    Martins, D.A.3    Kimbell, J.S.4
  • 18
    • 75749152943 scopus 로고    scopus 로고
    • Septal deviation and nasal resistance: An investigation using virtual surgery and computational fluid dynamics
    • Garcia GJM, Rhee JS, Senior BA, Kimbell JS. Septal deviation and nasal resistance: An investigation using virtual surgery and computational fluid dynamics. Am J Rhinol Allerg 2009; 24: e46-53.
    • (2009) Am J Rhinol Allerg , vol.24
    • Garcia, G.J.M.1    Rhee, J.S.2    Senior, B.A.3    Kimbell, J.S.4
  • 20
    • 84862167892 scopus 로고    scopus 로고
    • Computed nasal resistance compared with patient-reported symptoms in surgically treated nasal airway passages: A Preliminary Report
    • Kimbell JS, Garcia GJ, Frank DO, Cannon DE, Pawar S, Rhee JS. Computed nasal resistance compared with patient-reported symptoms in surgically treated nasal airway passages: A Preliminary Report. Am J Rhinol Allergy. 2012; 26: 94-98.
    • (2012) Am J Rhinol Allergy. , vol.26 , pp. 94-98
    • Kimbell, J.S.1    Garcia, G.J.2    Frank, D.O.3    Cannon, D.E.4    Pawar, S.5    Rhee, J.S.6
  • 21
    • 77955018407 scopus 로고    scopus 로고
    • Objective measures in aesthetic and functional nasal surgery: Perspectives on nasal form and function
    • Pawar SS, Garcia GJ, Kimbell JS, Rhee JS. Objective measures in aesthetic and functional nasal surgery: perspectives on nasal form and function. Facial Plast Surg. 2010; 26: 320-327.
    • (2010) Facial Plast Surg. , vol.26 , pp. 320-327
    • Pawar, S.S.1    Garcia, G.J.2    Kimbell, J.S.3    Rhee, J.S.4
  • 23
    • 78650607389 scopus 로고    scopus 로고
    • Effects of Surface Smoothness on Inertial Particle Deposition in Human Nasal Models
    • Schroeter JD, Garcia GJ, Kimbell JS. Effects of Surface Smoothness on Inertial Particle Deposition in Human Nasal Models. J Aerosol Sci. 2011; 42: 52-63.
    • (2011) J Aerosol Sci. , vol.42 , pp. 52-63
    • Schroeter, J.D.1    Garcia, G.J.2    Kimbell, J.S.3
  • 24
    • 53849119850 scopus 로고    scopus 로고
    • Numerical simulations investigating the regional and overall deposition efficiency of the human nasal cavity
    • Shanley KT, Zamankhan P, Ahmadi G, Hopke PK, Cheng YS. Numerical simulations investigating the regional and overall deposition efficiency of the human nasal cavity. Inhalation Toxicol. 2008; 20: 1093-1100.
    • (2008) Inhalation Toxicol. , vol.20 , pp. 1093-1100
    • Shanley, K.T.1    Zamankhan, P.2    Ahmadi, G.3    Hopke, P.K.4    Cheng, Y.S.5
  • 25
    • 70349964535 scopus 로고    scopus 로고
    • Indicators for the correct usage of intranasal medications: A computational fluid dynamics study
    • Garlapati RR, Lee HP, Chong FH, Wang DY. Indicators for the correct usage of intranasal medications: A computational fluid dynamics study. Laryngoscope 2009; 119: 1975-1982.
    • (2009) Laryngoscope , vol.119 , pp. 1975-1982
    • Garlapati, R.R.1    Lee, H.P.2    Chong, F.H.3    Wang, D.Y.4
  • 26
    • 77958137641 scopus 로고    scopus 로고
    • A computational fluid dynamics model for drug delivery in a nasal cavity with inferior turbinate hypertrophy
    • Chen XB, Lee HP, Chong VF, Wang de Y. A computational fluid dynamics model for drug delivery in a nasal cavity with inferior turbinate hypertrophy. J Aerosol Med Pulm Drug Deliv. 2010; 23: 329-338.
    • (2010) J Aerosol Med Pulm Drug Deliv. , vol.23 , pp. 329-338
    • Chen, X.B.1    Lee, H.P.2    Chong, V.F.3    de Wang, Y.4
  • 27
    • 77957588347 scopus 로고    scopus 로고
    • Numerical simulation of the effects of inferior turbinate surgery on nasal airway heating capacity
    • Chen XB, Lee HP, Chong VF, Wang DY. Numerical simulation of the effects of inferior turbinate surgery on nasal airway heating capacity. Am J Rhinol Allergy. 2010; 24: e118-122.
    • (2010) Am J Rhinol Allergy. , vol.24
    • Chen, X.B.1    Lee, H.P.2    Chong, V.F.3    Wang, D.Y.4
  • 28
    • 77953015909 scopus 로고    scopus 로고
    • A review of the implications of computational fluid dynamic studies on nasal airflow and physiology
    • Leong SC, Chen XB, Lee HP, Wang DY. A review of the implications of computational fluid dynamic studies on nasal airflow and physiology. Rhinology. 2010; 48: 139-145.
    • (2010) Rhinology. , vol.48 , pp. 139-145
    • Leong, S.C.1    Chen, X.B.2    Lee, H.P.3    Wang, D.Y.4
  • 29
    • 67349115950 scopus 로고    scopus 로고
    • Comparison of micron-and nanoparticle deposition patterns in a realistic human nasal cavity
    • Wang SM, Inthavong K, Wen J, Tu JY, Xue CL. Comparison of micron-and nanoparticle deposition patterns in a realistic human nasal cavity. Respir Physiol Neurobiol. 2009; 166:142-151.
    • (2009) Respir Physiol Neurobiol. , vol.166 , pp. 142-151
    • Wang, S.M.1    Inthavong, K.2    Wen, J.3    Tu, J.Y.4    Xue, C.L.5
  • 30
    • 78650723580 scopus 로고    scopus 로고
    • Simulation of sprayed particle deposition in a human nasal cavity including a nasal spray device
    • Inthavong K, Ge Q, Se CMK, Yang W, Tu JY. Simulation of sprayed particle deposition in a human nasal cavity including a nasal spray device. J Aerosol Sci. 2011; 42: 100-113.
    • (2011) J Aerosol Sci. , vol.42 , pp. 100-113
    • Inthavong, K.1    Ge, Q.2    Se, C.M.K.3    Yang, W.4    Tu, J.Y.5
  • 31
    • 84862908941 scopus 로고    scopus 로고
    • A numerical study of spray particle deposition in a human nasal cavity
    • Inthavong K, Tian ZF, Li HFet al. A numerical study of spray particle deposition in a human nasal cavity. Aerosol Sci Technol. 2006; 40: 1034-1045.
    • (2006) Aerosol Sci Technol. , vol.40 , pp. 1034-1045
    • Inthavong, K.1    Tian, Z.F.2    Li, H.F.3
  • 32
    • 44549088900 scopus 로고    scopus 로고
    • Optimising nasal spray parameters for efficient drug delivery using computational fluid dynamics
    • Inthavong K, Tian ZF, Tu JY, Yang W, Xue C. Optimising nasal spray parameters for efficient drug delivery using computational fluid dynamics. Comp Biol Med. 2008; 38: 713-726.
    • (2008) Comp Biol Med. , vol.38 , pp. 713-726
    • Inthavong, K.1    Tian, Z.F.2    Tu, J.Y.3    Yang, W.4    Xue, C.5
  • 35
    • 0029844354 scopus 로고    scopus 로고
    • Quantifying the distribution of inhalation exposure in human populations: Distribution of minute volumes in adults and children
    • Beals JA, Funk LM, Fountain R, Sedman R. Quantifying the distribution of inhalation exposure in human populations: distribution of minute volumes in adults and children. Environ Health Perspect. 1996; 104: 974-979.
    • (1996) Environ Health Perspect. , vol.104 , pp. 974-979
    • Beals, J.A.1    Funk, L.M.2    Fountain, R.3    Sedman, R.4
  • 36
    • 0036147554 scopus 로고    scopus 로고
    • Validity of in vitro tests on aqueous spray pumps as surrogates for nasal deposition
    • Suman JD, Laube BL, Lin TC, Brouet G, Dalby R. Validity of in vitro tests on aqueous spray pumps as surrogates for nasal deposition. Pharmaceut Res. 2002; 19: 1-6.
    • (2002) Pharmaceut Res. , vol.19 , pp. 1-6
    • Suman, J.D.1    Laube, B.L.2    Lin, T.C.3    Brouet, G.4    Dalby, R.5
  • 37
    • 0022586321 scopus 로고
    • A comparison of the regional deposition in a model nose of a drug discharged from metered aerosol and metered-pump nasal delivery systems
    • Hallworth GW, Padfield JM. A comparison of the regional deposition in a model nose of a drug discharged from metered aerosol and metered-pump nasal delivery systems. J Allergy Clin Immunol. 1986; 77: 348-353.
    • (1986) J Allergy Clin Immunol. , vol.77 , pp. 348-353
    • Hallworth, G.W.1    Padfield, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.