A stand-alone adenylation domain forms amide bonds in streptothricin biosynthesis

Nature Chemical Biology

Volumn 8, Issue 9, 2012, Pages 791-797

  Maruyama, Chitose ^a   Toyoda, Junya ^a   Kato, Yasuo ^b   Izumikawa, Miho ^c   Takagi, Motoki ^c   Shin Ya, Kazuo ^d   Katano, Hajime ^a   Utagawa, Takashi ^a   Hamano, Yoshimitsu ^a  

^a Fukui Prefectural Universifty ^*  (Japan)

^b TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^c Koto ku   (Japan)

^d NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; BACTERIAL PROTEIN; LYSINE; NONRIBOSOMAL PEPTIDE SYNTHETASE; OLIGOPEPTIDE; PROTEIN ORF18; PROTEIN ORF19; PROTEIN ORF5; STREPTOTHRICIN; UNCLASSIFIED DRUG;

ADENYLATION; ANTIBIOTIC BIOSYNTHESIS; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; BIOLOGICAL ACTIVITY; CATALYSIS; CHEMICAL BOND; CHEMICAL MODIFICATION; CHEMICAL REACTION; COVALENT BOND; ENZYME SUBSTRATE; GEL FILTRATION CHROMATOGRAPHY; GENE CLUSTER; GENE INACTIVATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; STREPTOMYCES; STREPTOMYCES ROCHEI; STRUCTURE ACTIVITY RELATION;

STREPTOMYCES;

EID: 84865335226     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1040     Document Type: Article

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