In situ application of hydrogel-type fibrin-islet composite optimized for rapid glycemic control by subcutaneous xenogeneic porcine islet transplantation

Journal of Controlled Release

Volumn 162, Issue 2, 2012, Pages 382-390

  Kim, Jung Sik ^a,b,c   Lim, Jong Hyung ^a,b,c   Nam, Hye Young ^a,b,c   Lim, Hyun Ju ^a,b,c   Shin, Jun Seop ^a,b,c   Shin, Jin Young ^a,b,c   Ryu, Ju Hee ^d   Kim, Kwangmeyung ^d   Kwon, Ick Chan ^d   Jin, Sang Man ^e   Kim, Hang Rae ^c   Kim, Sang Joon ^b   Park, Chung Gyu ^a,b,c  

^a Seoul National University   (South Korea)

^b Seoul National University Hospital   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

^d Korea Institute of Science and Technology   (South Korea)

^e Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Fibrin; Porcine islet; Subcutaneous islet transplantation; Xenotransplantation

Indexed keywords

ANGIOGENESIS; CLINICAL APPLICATION; DIABETIC MICE; ENGRAFTMENT; FIBRIN; GLYCEMIC CONTROL; IN-SITU; IN-VIVO; ISLET TRANSPLANTATION; MECHANISTIC STUDIES; OUTER SURFACE; PORCINE ISLET; SINGLE CELLS; VASCULARIZATION; XENOTRANSPLANTATION;

GRAFTS; OPTIMIZATION;

HYDROGELS;

FIBRIN; FIBRINOGEN; THROMBIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; COMPOSITE MATERIAL; CONTROLLED STUDY; DIABETES CONTROL; DIABETES MELLITUS; GLYCEMIC CONTROL; HYDROGEL; IN VIVO STUDY; KIDNEY CAPSULE; MOUSE; NONHUMAN; ORGAN WEIGHT; PANCREAS FUNCTION; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; REVASCULARIZATION; SUBCUTANEOUS ISLET TRANSPLANTATION; SUBCUTANEOUS TISSUE; SWINE; XENOGRAFT; XENOTRANSPLANTATION;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS; FIBRIN; HYDROGELS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED NOD; MICE, SCID; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84865327127     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.07.018     Document Type: Article

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