Predicting weight loss of obese adolescents in lifestyle interventions by genetic screening: A promising approach for researchers and clinicians?

Journal of Pediatrics

Volumn 161, Issue 3, 2012, Pages 382-384

  Reinehr, Thomas ^a  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; LEPTIN RECEPTOR; MELANOCORTIN 4 RECEPTOR; PROOPIOMELANOCORTIN;

BODY MASS; CHILDHOOD OBESITY; EDITORIAL; FOLLOW UP; GENE LOCUS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; HEALTH BEHAVIOR; HUMAN; LIFESTYLE MODIFICATION; PRIORITY JOURNAL; SAMPLE SIZE; SINGLE NUCLEOTIDE POLYMORPHISM; WEIGHT REDUCTION;

BODY MASS INDEX; FEMALE; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; WEIGHT LOSS;

EID: 84865309614     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2012.04.067     Document Type: Editorial

References (9)

1. J. Hebebrand, C. Sommerlad, F. Geller, T. Görg, and A. Hinney The genetics of obesity: practical implications Int J Obes Relat Metab Disord 25 Suppl 1 2001 S10 S18
2. A. Hinney, C.I. Vogel, and J. Hebebrand From monogenic to polygenic obesity: recent advances Eur Child Adolesc Psychiatry 19 2010 297 310
3. E.K. Speliotes, C.J. Willer, S.I. Berndt, K.L. Monda, G. Thorleifsson, and A.U. Jackson Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index Nat Genet 42 2010 937 948
4. A. Moleres, T. Rendo-Urteaga, M.A. Zulet, A. Marcos, C. Campoy, and J.M. Garagorri Obesity susceptibility loci on body mass index and weight loss in Spanish adolescents after a lifestyle intervention J Pediatr 161 2012 466 470
5. C.H. Andreasen, K.L. Stender-Petersen, M.S. Mogensen, S.S. Torekov, L. Wegner, and G. Andersen Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation Diabetes 57 2008 95 101
6. M. Juonala, J. Juhola, C.G. Magnussen, P. Würtz, J.S. Viikari, and R. Thomson Childhood environmental and genetic predictors of adulthood obesity: the Cardiovascular Risk in Young Finns Study J Clin Endocrinol Metab 96 2011 E1542 E1549
7. T. Reinehr, J. Hebebrand, S. Friedel, A.M. Toschke, H. Brumm, and H. Biebermann Lifestyle intervention in obese children with variations in the melanocortin 4 receptor gene Obesity (Silver Spring) 17 2009 382 389
8. F.I. Milagro, J. Campion, P. Cordero, E. Goyenechea, A.M. Gómez-Uriz, and I. Abete A dual epigenomic approach for the search of obesity biomarkers: DNA methylation in relation to diet-induced weight loss FASEB J 25 2011 1378 1389
9. T. Reinehr, K. Widhalm, D. l'Allemand, S. Wiegand, M. Wabitsch, and R.W. Holl Two-year follow-up in 21,784 overweight children and adolescents with lifestyle intervention Obesity (Silver Spring) 17 2009 1196 1199