Chemical composition, olfactory analysis and antibacterial activity of Thymus vulgaris chemotypes geraniol, 4-thujanol/terpinen-4-ol, thymol and linalool cultivated in Southern France

Natural Product Communications

Volumn 7, Issue 8, 2012, Pages 1095-1098

  Schmidt, Erich ^a   Wanner, Jürgen ^b   Höferl, Martina ^a   Jirovetz, Leopold ^a   Buchbauer, Gerhard ^a   Gochev, Velizar ^c   Girova, Tania ^c   Stoyanova, Albena ^d   Geissler, Margit ^e  

^a UNIVERSITY OF VIENNA   (Austria)

^b Kurt Kitzing Co   (Germany)

^c UNIVERSITY OF PLOVDIV   (Bulgaria)

^d UNIVERSITY OF FOOD TECHNOLOGIES   (Bulgaria)

^e Shimadzu Germany ^*  (Germany)

Author keywords

Antibacterial activity; Chemotype; Essential oil; Thymus vulgaris

Indexed keywords

4 THUJANOL; AMOXICILLIN; CEFAZOLIN; CIPROFLOXACIN; ESSENTIAL OIL; GERANIOL; LINALOOL; NALIDIXIC ACID; TERPINEN 4 OL; THYMOL; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; BROCHOTHRIX THERMOSPHACTA; CHEMICAL COMPOSITION; CONTROLLED STUDY; DRUG POTENCY; ESCHERICHIA COLI; FRANCE; GAS CHROMATOGRAPHY; MASS FRAGMENTOGRAPHY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; ODOR; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS FRAGI; SALMONELLA; SALMONELLA ABONY; STAPHYLOCOCCUS AUREUS; THYME;

EID: 84865296210     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x1200700833     Document Type: Article

References (39)

1. (a) Morales R. (2001) The history botany and taxonomy of the genus Thymus. In Thyme. The genus Thymus. Stahl-Biskup E, Sáez F. (Eds), Taylor and Francis, London, UK. 1-43;
2. (b) Stahl-Biskup E. (2001) Essential oil chemistry of the genus Thymus - a global view. In Thyme. The genus Thymus. Stahl-Biskup E, Sáez F (Eds), Taylor and Francis, London, UK. 75-124.
3. Wichtl M. (Ed.) (2009) Teedrogen und Phytopharmaka., Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, Germany.
4. (a) Meister A, Bernhardt G, Christoffel V, Buschauer A. (1999) Antispasmodic activity of Thymus vulgaris extract on the isolated Guinea-pig trachea: discrimination between drug and ethanol effects. Planta Medica, 65, 512-516;
5. (b) Wienkötter N, Begrow F, Kinzinger U, Schierstedt D, Verspohl EJ. (2007) The effect of thyme extract on beta2-receptors and mucociliary clearance. Planta Medica, 73, 629-635;
6. (c) Hammer KA, Carson CF, Riley TV. (1999) Antimicrobial activity of essential oils and other plant extracts. Journal of Applied Microbiology, 86, 985-990.
7. (a) Hotta M, Nakata R, Katsukawa M, Hori K, Takahashi S, Inoue H. (2010) Carvacrol, a component of thyme oil, activates PPARα and γ and suppresses COX-2 expression. Journal of Lipid Research, 51, 132-139;
8. (b) Soković, MD, Vukojević J, Marin PD, Brkić DD, Vajs V, van Griensven LJ. (2009) Chemical composition of essential oils of Thymus and Mentha species and their antifungal activities. Molecules, 14, 238-249.
9. (a) Astani A, Reichling J, Schnitzler P. (2010) Comparative study on the antiviral activity of selected monoterpenes derived from essential oils. Phytotherapy Research, 24, 673-679;
10. (b) Zu Y, Yu H, Liang L, Fu Y, Efferth T, Liu X, Wu N. (2010) Activities of ten essential oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer cells. Molecules, 15, 3200-3210.
11. Wei A, Shibamoto T. (2010) Antioxidant/lipoxygenase inhibitory activities and chemical compositions of selected essential oils. Journal of Agricultural and Food Chemistry, 58, 7218-7225.
12. Granger R, Passet J. (1973) T. vulgaris spontané de France: Races chimiques et chemotaxonomie. Phytochemistry, 12, 1683-1691.
13. (a) Kaloustian J, Abou L, Mikail C, Amiot MJ, Portugal H. (2005) Southern French thyme oils: chromatographic study of chemotypes. Journal of the Science of Food and Agriculture, 85, 2437-2444;
14. (b) Franz C. (1993) Genetics. In Volatile oil crops: their biology, biochemistry and production. Hay RKM, Waterman PG. (Eds), Longman Scientific & Technical, Harlow. 63-96;
15. (c) Desjardins AE. (2008) Natural product chemistry meets genetics: when is a genotype a chemotype? Journal of Agricultural and Food Chemistry, 56, 7587-7592.
16. Rohloff J. (2003) Cultivation of Herbs and Medicinal Plants in Norway - Essential Oil Production and Quality Control (PhD thesis), Norwegian University of Science and Technology, Trondheim, Norway. 8-9.
17. Thompson JD, Calchat JC, Michet A, Linhart YB, Ehlers B. (2003) Qualitative and quantitative variation in monoterpene co-occurrence and composition in the essential oil of Thymus vulgaris chemotypes. Journal of Chemical Ecology, 29, 859-880.
18. Echeverrigaray S, Agostini G, Atti-Serfini L, Paroul N, Pauletti GF, Atti dos Santos AC. (2001) Correlation between the chemical and genetic relationships among commercial thyme cultivars. Journal of Agricultural and Food Chemistry, 49, 4220-4223.
19. De Martino L, De Feo V, Nazzaro F. (2009) Chemical composition and in vitro antimicrobial and mutagenic activities of seven Lamiaceae essential oils. Molecules, 14, 4213-30.
20. Arctander S. (1961) Arctander's Perfume and Flavour Materials of Natural Origin. Allured books, Illinois.
21. (a) Dorman HJ, Deans SG. (2000) Antimicrobial agents from plants: antibacterial activity of plant volatile oils. Journal of Applied Microbiology, 88, 308-316;
22. (b) Veldhuizen EA, Tjerdsmaa-van Bokhoven JLM, Zweijtzer C, Burt SA, Haagsman HP. (2006) Structural requirements for the antimicrobial activity of carvacrol. Journal of Agricultural and Food Chemistry, 54, 1874-1879;
23. (c) Kamatou GPP, Viljoen AM. (2008) Linalool - A review of a biologically active compound of commercial importance. Natural Product Communications, 3, 1183-1192.
24. Iten F, Saller R, Abel G, Reichling R. (2009) Additive antimicrobial effects of the active components of the essential oil of Thymus vulgaris chemotype carvacrol. Planta Medica, 75, 1231-1236.
25. Jirovetz L, Schmidt E, Denkova Z, Stoyanova A, Nikolova R. (2007) Purity, antimicrobial activities and olfactoric evaluations of geraniol/nerol and various of their derivatives. Journal of Essential Oil Research, 19, 288-291.
26. Höferl M, Buchbauer G, Jirovetz L, Schmidt E, Stoyanova A, Denkova Z, Slavchev A, Geissler M. (2009) Correlation of antimicrobial activities of various essential oils and their main aromatic volatile constituents. Journal of Essential Oil Research, 21, 459-463.
27. Bozin B, Mimica-Dukic N, Simin N, Anackow G. (2006) Characterization of the volatile composition of essential oils of some Lamiaceae spices and the antimicrobial and antioxidant activities of the entire oils. Journal of Agricultural and Food Chemistry, 54, 1822-1828.
28. (a) Marino M, Bersani C, Comi, G. (1999) Antimicrobial activity of the essential oils of Thymus vulgaris L. measured using a bioimpedometric method. Journal of Food Protection, 62, 1017-1023;
29. (b) Warnke PH, Becker ST, Podschun R, Sivananthan S, Springer IN, Russo PA, Wiltfang J, Fickenscher H, Sherry E. (2009) The battle against multi-resistant strains: Renaissance of antimicrobial essential oils as a promising force to fight hospital-acquired infections. Journal of Craniomaxillofacial Surgery, 37, 392-397.
30. Fratianni F, De Martino L, Melone A, De Feo V, Coppola R, Nazzaro F. (2010) Preservation of chicken breast meat treated with thyme and balm essential oils. Journal of Food Science, 75, M528-M535.
31. Irkin R, Korukluoglu M. (2009) Growth inhibition of pathogenic bacteria and some yeasts by selected essential oils and survival of L. monocytogenes and C. albicans in apple-carrot juice. Foodborne Pathogens and Disease, 6, 387-394.
32. Schmidt E, Bail S, Buchbauer G, Stoilova I, Atanasova T, Stoyanova A, Krastanov A, Jirovetz L. (2009) Chemical composition, olfactory evaluation and antioxidant effects of essential oil from Mentha x piperita. Natural Product Communications, 4, 1107-1112.
33. (a) Adams RP. (2007) Identification of Essential Oil Components by Gas Chromatography /Quadrupole Mass Spectroscopy. Allured Publishing, Illinois;
34. (b) Joulain D, König WA. (1998) The Atlas of Spectral Data of Sesquiterpene Hydrocarbons, E.B.-Verlag, Hamburg;
35. (c) Kondjoyan N, Berdaque JL. (1996) A compilation of relative retention indices for the analysis of aromatic compounds, Edition du Laboratoire Flaveur, Saint Genes Champanelle;
36. (d) Davies NW. (1990) Gas chromatographic retention indices of monoterpenes and sesquiterpenes on methyl silicon and Carbowax 20M phases. Journal of Chromatography A, 503, 1-24;
37. (e) Jennings W, Shibamoto T. (1980) Qualitative analysis of flavour and fragrance volatiles by glass capillary gas chromatography, Academic Press, New York
38. National Committee Clinical Laboratory Standards. (1990) Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically. Approved Standard. NCCLS Publication M7-A2,Villanova
39. National Committee Clinical Laboratory Standards. (2002) Reference methods for broth dilution and fungal susceptibility testing of yeasts, Approved Standard, -Publications M27-A2, Wayne.