메뉴 건너뛰기




Volumn 12, Issue , 2012, Pages

The effect of sulindac, a non-steroidal anti-inflammatory drug, attenuates inflammation and fibrosis in a mouse model of chronic pancreatitis

Author keywords

Chemoprevention; Chronic pancreatitis; Sulindac

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CERULETIDE; GLI PROTEIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SONIC HEDGEHOG PROTEIN; SULINDAC; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84865289194     PISSN: None     EISSN: 1471230X     Source Type: Journal    
DOI: 10.1186/1471-230X-12-115     Document Type: Article
Times cited : (30)

References (38)
  • 1
    • 33746156525 scopus 로고    scopus 로고
    • A selective COX-2 inhibitor suppresses chronic pancreatitis in an animal model (WBN/Kob rats): significant reduction of macrophage infiltration and fibrosis
    • 1856270, 16322109
    • Reding T, et al. A selective COX-2 inhibitor suppresses chronic pancreatitis in an animal model (WBN/Kob rats): significant reduction of macrophage infiltration and fibrosis. Gut 2006, 55(8):1165-1173. 1856270, 16322109.
    • (2006) Gut , vol.55 , Issue.8 , pp. 1165-1173
    • Reding, T.1
  • 2
    • 77954376035 scopus 로고    scopus 로고
    • Angiotensin II signaling through the AT1a and AT1b receptors does not have a role in the development of cerulein-induced chronic pancreatitis in the mouse
    • 10.1152/ajpgi.00006.2010, 20413721
    • Ulmasov B, et al. Angiotensin II signaling through the AT1a and AT1b receptors does not have a role in the development of cerulein-induced chronic pancreatitis in the mouse. Am J Physiol Gastrointest Liver Physiol 2010, 299(1):G70-G80. 10.1152/ajpgi.00006.2010, 20413721.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.299 , Issue.1
    • Ulmasov, B.1
  • 3
    • 56649114152 scopus 로고    scopus 로고
    • Mechanisms of pancreatic fibrosis and applications to the treatment of chronic pancreatitis
    • 10.1007/s00535-008-2249-7, 19012035
    • Shimizu K. Mechanisms of pancreatic fibrosis and applications to the treatment of chronic pancreatitis. J Gastroenterol 2008, 43(11):823-832. 10.1007/s00535-008-2249-7, 19012035.
    • (2008) J Gastroenterol , vol.43 , Issue.11 , pp. 823-832
    • Shimizu, K.1
  • 4
    • 77955165771 scopus 로고    scopus 로고
    • Connective tissue growth factor production by activated pancreatic stellate cells in mouse alcoholic chronic pancreatitis
    • 10.1038/labinvest.2010.82, 2901405, 20368699
    • Charrier AL, Brigstock DR. Connective tissue growth factor production by activated pancreatic stellate cells in mouse alcoholic chronic pancreatitis. Lab Invest 2010, 90(8):1179-1188. 10.1038/labinvest.2010.82, 2901405, 20368699.
    • (2010) Lab Invest , vol.90 , Issue.8 , pp. 1179-1188
    • Charrier, A.L.1    Brigstock, D.R.2
  • 5
    • 0037962905 scopus 로고    scopus 로고
    • Cell migration: a novel aspect of pancreatic stellate cell biology
    • 10.1136/gut.52.5.677, 1773645, 12692052
    • Phillips PA, et al. Cell migration: a novel aspect of pancreatic stellate cell biology. Gut 2003, 52(5):677-682. 10.1136/gut.52.5.677, 1773645, 12692052.
    • (2003) Gut , vol.52 , Issue.5 , pp. 677-682
    • Phillips, P.A.1
  • 6
    • 0036282292 scopus 로고    scopus 로고
    • Pancreatic stellate cells respond to inflammatory cytokines: potential role in chronic pancreatitis
    • 10.1136/gut.50.4.535, 1773172, 11889076
    • Mews P, et al. Pancreatic stellate cells respond to inflammatory cytokines: potential role in chronic pancreatitis. Gut 2002, 50(4):535-541. 10.1136/gut.50.4.535, 1773172, 11889076.
    • (2002) Gut , vol.50 , Issue.4 , pp. 535-541
    • Mews, P.1
  • 7
    • 37249092998 scopus 로고    scopus 로고
    • Pancreatic stellate cells: new target in the treatment of chronic pancreatitis
    • Talukdar R, Tandon RK. Pancreatic stellate cells: new target in the treatment of chronic pancreatitis. J Gastroenterol Hepatol 2008, 23(1):34-41.
    • (2008) J Gastroenterol Hepatol , vol.23 , Issue.1 , pp. 34-41
    • Talukdar, R.1    Tandon, R.K.2
  • 8
    • 84863153557 scopus 로고    scopus 로고
    • L-cysteine administration attenuates pancreatic fibrosis induced by TNBS in rats by inhibiting the activation of pancreatic stellate cell
    • 10.1371/journal.pone.0031807, 3281011, 22359633
    • Yang L, et al. L-cysteine administration attenuates pancreatic fibrosis induced by TNBS in rats by inhibiting the activation of pancreatic stellate cell. PLoS One 2012, 7(2):e31807. 10.1371/journal.pone.0031807, 3281011, 22359633.
    • (2012) PLoS One , vol.7 , Issue.2
    • Yang, L.1
  • 9
    • 0141842604 scopus 로고    scopus 로고
    • Distribution of Indian hedgehog and its receptors patched and smoothened in human chronic pancreatitis
    • 10.1677/joe.0.1780467, 12967338
    • Kayed H, et al. Distribution of Indian hedgehog and its receptors patched and smoothened in human chronic pancreatitis. J Endocrinol 2003, 178(3):467-478. 10.1677/joe.0.1780467, 12967338.
    • (2003) J Endocrinol , vol.178 , Issue.3 , pp. 467-478
    • Kayed, H.1
  • 10
    • 44449138137 scopus 로고    scopus 로고
    • Indian hedgehog promotes the migration of rat activated pancreatic stellate cells by increasing membrane type-1 matrix metalloproteinase on the plasma membrane
    • 10.1002/jcp.21372, 18286538
    • Shinozaki S, et al. Indian hedgehog promotes the migration of rat activated pancreatic stellate cells by increasing membrane type-1 matrix metalloproteinase on the plasma membrane. J Cell Physiol 2008, 216(1):38-46. 10.1002/jcp.21372, 18286538.
    • (2008) J Cell Physiol , vol.216 , Issue.1 , pp. 38-46
    • Shinozaki, S.1
  • 11
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: structural, cellular, and molecular biology
    • 10.1146/annurev.biochem.69.1.145, 10966456
    • Smith WL, DeWitt DL, Garavito RM. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 2000, 69:145-182. 10.1146/annurev.biochem.69.1.145, 10966456.
    • (2000) Annu Rev Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    DeWitt, D.L.2    Garavito, R.M.3
  • 12
    • 0035990225 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is overexpressed in chronic pancreatitis
    • 10.1097/00006676-200207000-00008, 12131767
    • Schlosser W, et al. Cyclooxygenase-2 is overexpressed in chronic pancreatitis. Pancreas 2002, 25(1):26-30. 10.1097/00006676-200207000-00008, 12131767.
    • (2002) Pancreas , vol.25 , Issue.1 , pp. 26-30
    • Schlosser, W.1
  • 13
    • 79957948001 scopus 로고    scopus 로고
    • COX-2 is not required for the development of murine chronic pancreatitis
    • 10.1152/ajpgi.00497.2010, 21372163
    • Silva A, et al. COX-2 is not required for the development of murine chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol 2011, 300(6):G968-G975. 10.1152/ajpgi.00497.2010, 21372163.
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.300 , Issue.6
    • Silva, A.1
  • 14
    • 77958536786 scopus 로고    scopus 로고
    • Flavocoxid, a dual inhibitor of cyclooxygenase-2 and 5-lipoxygenase, reduces pancreatic damage in an experimental model of acute pancreatitis
    • 10.1111/j.1476-5381.2010.00933.x, 2998682, 20977452
    • Polito F, et al. Flavocoxid, a dual inhibitor of cyclooxygenase-2 and 5-lipoxygenase, reduces pancreatic damage in an experimental model of acute pancreatitis. Br J Pharmacol 2010, 161(5):1002-1011. 10.1111/j.1476-5381.2010.00933.x, 2998682, 20977452.
    • (2010) Br J Pharmacol , vol.161 , Issue.5 , pp. 1002-1011
    • Polito, F.1
  • 15
    • 84155170905 scopus 로고    scopus 로고
    • Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-E(2) in the spinal cord
    • 10.1016/j.pain.2011.09.021, 22030324
    • Marshall TM, et al. Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-E(2) in the spinal cord. Pain 2012, 153(1):86-94. 10.1016/j.pain.2011.09.021, 22030324.
    • (2012) Pain , vol.153 , Issue.1 , pp. 86-94
    • Marshall, T.M.1
  • 16
    • 77949524833 scopus 로고    scopus 로고
    • Prostaglandin E2 regulates the expression of connective tissue growth factor (CTGF/CCN2) in human osteoarthritic chondrocytes via the EP4 receptor
    • 10.1186/1756-0500-3-5, 2826353, 20205862
    • Masuko K, et al. Prostaglandin E2 regulates the expression of connective tissue growth factor (CTGF/CCN2) in human osteoarthritic chondrocytes via the EP4 receptor. BMC Res Notes 2010, 3:5. 10.1186/1756-0500-3-5, 2826353, 20205862.
    • (2010) BMC Res Notes , vol.3 , pp. 5
    • Masuko, K.1
  • 17
    • 77953374322 scopus 로고    scopus 로고
    • Resolution of inflammation in murine autoimmune arthritis is disrupted by cyclooxygenase-2 inhibition and restored by prostaglandin E2-mediated lipoxin A4 production
    • 10.4049/jimmunol.0903816, 3032587, 20435922
    • Chan MM, Moore AR. Resolution of inflammation in murine autoimmune arthritis is disrupted by cyclooxygenase-2 inhibition and restored by prostaglandin E2-mediated lipoxin A4 production. J Immunol 2010, 184(11):6418-6426. 10.4049/jimmunol.0903816, 3032587, 20435922.
    • (2010) J Immunol , vol.184 , Issue.11 , pp. 6418-6426
    • Chan, M.M.1    Moore, A.R.2
  • 18
    • 80755168365 scopus 로고    scopus 로고
    • Colon tumour cells increase PGE(2) by regulating COX-2 and 15-PGDH to promote survival during the microenvironmental stress of glucose deprivation
    • 10.1093/carcin/bgr210, 21926111
    • Roberts HR, et al. Colon tumour cells increase PGE(2) by regulating COX-2 and 15-PGDH to promote survival during the microenvironmental stress of glucose deprivation. Carcinogenesis 2011, 32(11):1741-1747. 10.1093/carcin/bgr210, 21926111.
    • (2011) Carcinogenesis , vol.32 , Issue.11 , pp. 1741-1747
    • Roberts, H.R.1
  • 19
    • 55949098253 scopus 로고    scopus 로고
    • Expression analysis of the prostaglandin E2 production pathway in human pancreatic cancers
    • 10.1097/MPA.0b013e31816618ba, 18665070
    • Hasan S, et al. Expression analysis of the prostaglandin E2 production pathway in human pancreatic cancers. Pancreas 2008, 37(2):121-127. 10.1097/MPA.0b013e31816618ba, 18665070.
    • (2008) Pancreas , vol.37 , Issue.2 , pp. 121-127
    • Hasan, S.1
  • 20
    • 33845989205 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is required for activated pancreatic stellate cells to respond to proinflammatory cytokines
    • Aoki H, et al. Cyclooxygenase-2 is required for activated pancreatic stellate cells to respond to proinflammatory cytokines. Am J Physiol Cell Physiol 2007, 292(1):C259-C268.
    • (2007) Am J Physiol Cell Physiol , vol.292 , Issue.1
    • Aoki, H.1
  • 21
    • 34249855319 scopus 로고    scopus 로고
    • Selective cyclooxygenase-2 inhibitor ameliorates cholecystokinin-octapeptide-induced acute pancreatitis in rats
    • Seo SW, et al. Selective cyclooxygenase-2 inhibitor ameliorates cholecystokinin-octapeptide-induced acute pancreatitis in rats. World J Gastroenterol 2007, 13(16):2298-2304.
    • (2007) World J Gastroenterol , vol.13 , Issue.16 , pp. 2298-2304
    • Seo, S.W.1
  • 22
    • 0034980582 scopus 로고    scopus 로고
    • Sulindac and its derivatives: a novel class of anticancer agents
    • Haanen C. Sulindac and its derivatives: a novel class of anticancer agents. Curr Opin Investig Drugs 2001, 2(5):677-683.
    • (2001) Curr Opin Investig Drugs , vol.2 , Issue.5 , pp. 677-683
    • Haanen, C.1
  • 23
  • 24
    • 19944403591 scopus 로고    scopus 로고
    • Novel antioxidant ameliorates the fibrosis and inflammation of cerulein-induced chronic pancreatitis in a mouse model
    • Yoo BM, et al. Novel antioxidant ameliorates the fibrosis and inflammation of cerulein-induced chronic pancreatitis in a mouse model. Pancreatology 2005, 5(2-3):165-176.
    • (2005) Pancreatology , vol.5 , Issue.2-3 , pp. 165-176
    • Yoo, B.M.1
  • 25
    • 84856606842 scopus 로고    scopus 로고
    • Animal models for investigating chronic pancreatitis
    • 10.1186/1755-1536-4-26, 3274456, 22133269
    • Aghdassi AA, et al. Animal models for investigating chronic pancreatitis. Fibrogenesis Tissue Repair 2011, 4(1):26. 10.1186/1755-1536-4-26, 3274456, 22133269.
    • (2011) Fibrogenesis Tissue Repair , vol.4 , Issue.1 , pp. 26
    • Aghdassi, A.A.1
  • 26
    • 0034087517 scopus 로고    scopus 로고
    • Repetitive self-limited acute pancreatitis induces pancreatic fibrogenesis in the mouse
    • 10.1023/A:1005423122127, 10759232
    • Neuschwander-Tetri BA, et al. Repetitive self-limited acute pancreatitis induces pancreatic fibrogenesis in the mouse. Dig Dis Sci 2000, 45(4):665-674. 10.1023/A:1005423122127, 10759232.
    • (2000) Dig Dis Sci , vol.45 , Issue.4 , pp. 665-674
    • Neuschwander-Tetri, B.A.1
  • 27
    • 33745890260 scopus 로고    scopus 로고
    • Review of experimental animal models of acute pancreatitis
    • Su KH, Cuthbertson C, Christophi C. Review of experimental animal models of acute pancreatitis. HPB (Oxford) 2006, 8(4):264-286.
    • (2006) HPB (Oxford) , vol.8 , Issue.4 , pp. 264-286
    • Su, K.H.1    Cuthbertson, C.2    Christophi, C.3
  • 28
    • 0031823483 scopus 로고    scopus 로고
    • The sulfide metabolite of sulindac prevents tumors and restores enterocyte apoptosis in a murine model of familial adenomatous polyposis
    • 10.1093/carcin/19.1.87, 9472698
    • Mahmoud NN, et al. The sulfide metabolite of sulindac prevents tumors and restores enterocyte apoptosis in a murine model of familial adenomatous polyposis. Carcinogenesis 1998, 19(1):87-91. 10.1093/carcin/19.1.87, 9472698.
    • (1998) Carcinogenesis , vol.19 , Issue.1 , pp. 87-91
    • Mahmoud, N.N.1
  • 29
    • 80755169509 scopus 로고    scopus 로고
    • Inhibition of chronic pancreatitis and pancreatic intraepithelial neoplasia (PanIN) by capsaicin in LSL-KrasG12D/Pdx1-Cre mice
    • 10.1093/carcin/bgr191, 21859833
    • Bai H, et al. Inhibition of chronic pancreatitis and pancreatic intraepithelial neoplasia (PanIN) by capsaicin in LSL-KrasG12D/Pdx1-Cre mice. Carcinogenesis 2011, 32(11):1689-1696. 10.1093/carcin/bgr191, 21859833.
    • (2011) Carcinogenesis , vol.32 , Issue.11 , pp. 1689-1696
    • Bai, H.1
  • 30
    • 0036313896 scopus 로고    scopus 로고
    • Inhibition of chronic ulcerative colitis-associated colorectal adenocarcinoma development in a murine model by N-acetylcysteine
    • 10.1093/carcin/23.6.993, 12082021
    • Seril DN, et al. Inhibition of chronic ulcerative colitis-associated colorectal adenocarcinoma development in a murine model by N-acetylcysteine. Carcinogenesis 2002, 23(6):993-1001. 10.1093/carcin/23.6.993, 12082021.
    • (2002) Carcinogenesis , vol.23 , Issue.6 , pp. 993-1001
    • Seril, D.N.1
  • 31
    • 79958832472 scopus 로고    scopus 로고
    • Oxidative stress in chronic pancreatitis: pathophysiological relevance and management
    • 10.1089/ars.2011.4115, 21902596
    • Tandon RK, Garg PK. Oxidative stress in chronic pancreatitis: pathophysiological relevance and management. Antioxid Redox Signal 2011, 15(10):2757-2766. 10.1089/ars.2011.4115, 21902596.
    • (2011) Antioxid Redox Signal , vol.15 , Issue.10 , pp. 2757-2766
    • Tandon, R.K.1    Garg, P.K.2
  • 32
    • 14644426005 scopus 로고    scopus 로고
    • Therapeutic effects of troglitazone in experimental chronic pancreatitis in mice
    • 10.1016/S0002-9440(10)62293-6, 1602356, 15743784
    • van Westerloo DJ, et al. Therapeutic effects of troglitazone in experimental chronic pancreatitis in mice. Am J Pathol 2005, 166(3):721-728. 10.1016/S0002-9440(10)62293-6, 1602356, 15743784.
    • (2005) Am J Pathol , vol.166 , Issue.3 , pp. 721-728
    • van Westerloo, D.J.1
  • 33
    • 55149097289 scopus 로고    scopus 로고
    • Tumor necrosis factor and cancer, buddies or foes?
    • 10.1111/j.1745-7254.2008.00889.x, 2631033, 18954521
    • Wang X, Lin Y. Tumor necrosis factor and cancer, buddies or foes?. Acta Pharmacol Sin 2008, 29(11):1275-1288. 10.1111/j.1745-7254.2008.00889.x, 2631033, 18954521.
    • (2008) Acta Pharmacol Sin , vol.29 , Issue.11 , pp. 1275-1288
    • Wang, X.1    Lin, Y.2
  • 34
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: linking inflammation and immunity to cancer development and progression
    • 10.1038/nri1703, 16175180
    • Karin M, Greten FR. NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 2005, 5(10):749-759. 10.1038/nri1703, 16175180.
    • (2005) Nat Rev Immunol , vol.5 , Issue.10 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 35
    • 75849117800 scopus 로고    scopus 로고
    • Inflammation and oncogenesis: a vicious connection
    • 10.1016/j.gde.2009.11.004, 2821983, 20036794
    • Grivennikov SI, Karin M. Inflammation and oncogenesis: a vicious connection. Curr Opin Genet Dev 2010, 20(1):65-71. 10.1016/j.gde.2009.11.004, 2821983, 20036794.
    • (2010) Curr Opin Genet Dev , vol.20 , Issue.1 , pp. 65-71
    • Grivennikov, S.I.1    Karin, M.2
  • 36
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • 10.1016/j.cell.2010.01.025, 2866629, 20303878
    • Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010, 140(6):883-899. 10.1016/j.cell.2010.01.025, 2866629, 20303878.
    • (2010) Cell , vol.140 , Issue.6 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 37
    • 0028270481 scopus 로고
    • Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant
    • 10.1073/pnas.91.9.3652, 43639, 8170963
    • Carr MW, et al. Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proc Natl Acad Sci U S A 1994, 91(9):3652-3656. 10.1073/pnas.91.9.3652, 43639, 8170963.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , Issue.9 , pp. 3652-3656
    • Carr, M.W.1
  • 38
    • 0037322618 scopus 로고    scopus 로고
    • Differential roles of signaling pathways for proliferation and migration of rat pancreatic stellate cells
    • 10.1620/tjem.199.69, 12705352
    • Masamune A, et al. Differential roles of signaling pathways for proliferation and migration of rat pancreatic stellate cells. Tohoku J Exp Med 2003, 199(2):69-84. 10.1620/tjem.199.69, 12705352.
    • (2003) Tohoku J Exp Med , vol.199 , Issue.2 , pp. 69-84
    • Masamune, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.