Mechanism of folate deficiency-induced apoptosis in mouse embryonic stem cells: Cell cycle arrest/apoptosis in G1/G0 mediated by microRNA-302a and tumor suppressor gene Lats2

International Journal of Biochemistry and Cell Biology

Volumn 44, Issue 11, 2012, Pages 1750-1760

  Liang, Yan ^a,b   Li, Yuanyuan ^b   Li, Zhengli ^b   Liu, Zhuo ^b   Zhang, Zhiping ^c   Chang, Shaoyan ^b   Wu, Jianxin ^a,b  

^a PEKING UNIVERSITY   (China)

^b CAPITAL INSTITUTE OF PEDIATRICS   (China)

^c Children's Hospital of Shanxi   (China)

Author keywords

Apoptosis; Cell cycle; Folate deficiency; Lats2; miR 302a

Indexed keywords

MESSENGER RNA; MICRORNA; MICRORNA 302A; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOINFORMATICS; CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CULTURE MEDIUM; EMBRYONIC STEM CELL; FOLIC ACID DEFICIENCY; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION PROFILING; GENE TARGETING; IN VITRO STUDY; MOUSE; NONHUMAN; TUMOR SUPPRESSOR GENE; TUMOR SUPPRESSOR GENE LATS2;

3' UNTRANSLATED REGIONS; ANIMALS; APOPTOSIS; BASE SEQUENCE; CELL CYCLE CHECKPOINTS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CULTURE MEDIA; EMBRYONIC STEM CELLS; FLOW CYTOMETRY; FOLIC ACID DEFICIENCY; G0 PHASE; G1 PHASE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; GENES, REPORTER; LUCIFERASES; MICE; MICRORNAS; MOLECULAR SEQUENCE DATA; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

MAMMALIA;

EID: 84865285558     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2012.07.014     Document Type: Article

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