Design, optimization and in vitro evaluation of reverse micelle-loaded lipid nanocarriers containing erlotinib hydrochloride

International Journal of Pharmaceutics

Volumn 436, Issue 1-2, 2012, Pages 194-200

  Vrignaud, Sandy ^a,b   Hureaux, José ^a,b   Wack, Séverine ^a   Benoit, Jean Pierre ^a,b,c   Saulnier, Patrick ^a  

^a UNIVERSITÉ D'ANGERS   (France)

^b ANGERS UNIVERSITY HOSPITAL   (France)

^c PSL RESEARCH UNIVERSITY   (France)

Author keywords

BxPC 3 cells; Lipid nanoparticles; PIT method; Polyoxyethylene sorbitan fatty acid esters; Sorbitan esters; Tyrosine kinase inhibitor

Indexed keywords

ERLOTINIB; NANOCARRIER; SOLUTOL HS 15; SORBITAN TRIOLEATE;

ARTICLE; CARCINOMA CELL; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DISPERSION; DRUG DESIGN; DRUG FORMULATION; DRUG SCREENING; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO STUDY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PRODUCTIVITY; REVERSE MICELLE; TEMPERATURE; ZETA POTENTIAL;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG CARRIERS; HUMANS; MICELLES; NANOPARTICLES; PROTEIN KINASE INHIBITORS; QUINAZOLINES; SURFACE-ACTIVE AGENTS; TRIGLYCERIDES;

EID: 84865282526     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.06.026     Document Type: Article

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