Reverse micelle-loaded lipid nano-emulsions: New technology for nano-encapsulation of hydrophilic materials

International Journal of Pharmaceutics

Volumn 398, Issue 1-2, 2010, Pages 204-209

  Anton, Nicolas ^a,b   Mojzisova, Halina ^c,d   Porcher, Emilien ^e   Benoit, Jean Pierre ^e,f   Saulnier, Patrick ^e  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b Faculté de Pharmacie   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d CNRS 7033   (France)

^e UNIVERSITÉ D'ANGERS   (France)

^f PSL RESEARCH UNIVERSITY   (France)

Author keywords

Hydrophilic material; Low energy method; Nano emulsification; Nano emulsion; Phase inversion temperature; PIT method; Reverse micelle

Indexed keywords

FLUORESCEIN SODIUM; LIPID EMULSION;

ARTICLE; DRUG FORMULATION; HYDROPHILICITY; NANOEMULSION; NANOENCAPSULATION; PRIORITY JOURNAL; REVERSE MICELLE; THERMODYNAMICS;

EMULSIONS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPIDS; MICELLES; NANOPARTICLES; NANOTECHNOLOGY;

EID: 77956210944     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.07.039     Document Type: Article

References (23)

1. Almeida A.J., Souto E. Solid lipid nanoparticles as a drug delivery system for peptides and proteins. Adv. Drug Deliv. Rev. 2007, 59:478-490.
2. Anton N., Benoit J.P., Saulnier P. Design and production of nanoparticles formulated from nano-emulsion templates: a review. J. Control Release 2008, 128:185-199.
3. Anton N., Gayet P., Benoit J.P., Saulnier P. Nano-emulsion and nanocapsules by the pit method: an investigation on the role of the temperature cycling on the emulsion phase inversion. Int. J. Pharm. 2007, 344:44-52.
4. Anton N., Saulnier P., Beduneau A., Benoit J.P. Salting-out effect induced by temperature cycling on a water/nonionic surfactant/oil system. J. Phys. Chem. B 2007, 111:3651-3657.
5. Anton N., Vandamme T. The universality of low-energy nano-emulsification. Int. J. Pharm. 2009, 377:142-147.
6. Béduneau A., Saulnier P., Anton N., Hindré F., Passirani C., Rajerison H., Noiret N., Benoit J.P. Pegylated nanocapsules produced by an organic solvent-free method: Evaluation of their stealth properties. Pharm. Res. 2006, 23:2190-2199.
7. Bouchemal K., Briançon S., Perrier E., Fessi H. Nano-emulsion formation using spontaneous emulsification: solvent, oil and surfactant optimisation. Int. J. Pharm. 2004, 280:241-251.
8. Forster T., von Rybinsky W., Wadle A. Influence of microemulsion phases on the preparation of fine-disperse emulsion. Adv. Colloid Interface Sci. 1995, 58:119-149.
9. Gomes J.F.P.d.S., Sonnen A.F.-P., Kronenberger A., Fritz J., Coelho M.A.N., Fournier D., Fournier-Noel C., Mauzac M., Winterhalter M. Stable polymethacrylate nanocapsules from ultraviolet light-induced template radical polymerization of unilamellar liposomes. Langmuir 2006, 22:7755-7759.
10. Heurtault B., Saulnier P., Pech B., Proust J.E., Richard J., Benoit J.P. A novel phase inversion-based process for the preparation of lipid nanocarriers. Pharm. Res. 2002, 19:875-880.
11. Hillaireau H., Le Doan T., Basnard M., Chacun H., Janin J., Couvreur P. Encapsulation of antiviral analogues azidothymidine-triphosphate and cidofovir in poly(iso-butylcyanoacrylate) nanocapsules. Int. J. Pharm. 2006, 324:37-42.
12. Lambert G., Fattal E., Pinto-Alphandary H., Gulik A., Couvreur P. Polyisobutylcyanoacrylate nanocapsules containing an aqueous core as a novel colloidal carrier for the delivery of oligonucleotides. Pharm. Res. 2000, 17:707-714.
13. Lambert B., Bertrand J.R., Fattal E., Subra F., Pinto-Alphandary H., Malvy C., Auclair C., Couvreur P. Ews fli-1 antisense nanocapsules inhibits ewing sarcoma-related tumor in mice. Biochem. Biophys. Res. Commun. 2000, 279:401-406.
14. Lamprecht A., Benoit J.P. Etoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous p-glycoprotein inhibition. J. Control Release 2006, 112:108-113.
15. Lamprecht A., Bouligand Y., Benoit J.P. New lipid nanocapsules exhibit sustained release properties for amiodarone. J. Control Release 2002, 84:59-68.
16. Morales D., Guiterrez J.M., Garcia-Celma M.J., Solans C. A study of the relation between bicontinuous microemulsions and oil/water nano-emulsion formation. Langmuir 2003, 19:7196-7200.
17. Perez C., Sanchez A., Putnam D., Ting D., Langer R., Alonso M.J. Poly(lactic acid)-poly(ethylene glycol) nanoparticles as a new carrier for the delivery of plasmid dna. J. Control Release 2001, 75:211-224.
18. Ruysschaert T., Paquereau L., Winterhalter M., Fournier D. Stabilization of liposomes through enzymatic polymerization of dna. Nano Lett. 2006, 6:2755-2757.
19. Salager J.L., Forgiarini A., Marquez L., Pena A., Pizzino P., Rodriguez P., Rondon-Gonzalez M. Using emulsion inversion in industrial processes. Adv. Colloid Interface Sci. 2004, 108-109:259-272.
20. Saulnier, P., Benoit, J., Anton, N., 2008. Nanocapusles with liquid lipidic core loaded with water-soluble or water-dispersible ingredient(s), Patent number WO2009/001019 A2.
21. Solans C., Izquierdo P., Nolla J., Azemar N., Garcia-Celma M.J. Nano-emulsion. Curr. Opin. Colloid Interface Sci. 2005, 10:102-110.
22. Tadros T.F., Izquierdo P., Esquena J., Solans C. Formation and stability of nano-emulsions. Adv. Colloid Interface Sci. 2004, 108-109:303-318.
23. Taylor P. Ostwald ripening in emulsions. Adv. Colloid Interface Sci. 1998, 75:107-163.