Humanin prevents intra-renal microvascular remodeling and inflammation in hypercholesterolemic ApoE deficient mice

Life Sciences

Volumn 91, Issue 5-6, 2012, Pages 199-206

  Zhang, Xin ^a   Urbieta Caceres, Victor H ^a   Eirin, Alfonso ^a   Bell, Caitlin C ^a   Crane, John A ^a   Tang, Hui ^a   Jordan, Kyra L ^a   Oh, Yun Kyu ^a   Zhu, Xiang Yang ^a   Korsmo, Michael J ^a   Bachar, Adi R ^a   Cohen, Pinchas ^b   Lerman, Amir ^a   Lerman, Lilach O ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Angiogenesis; Humanin; Hypercholesterolemia; Inflammation; Kidney disease

Indexed keywords

ANGIOPOIETIN 1; ANGIOSTATIN; APOLIPOPROTEIN E; COLLAGEN TYPE 4; HUMANIN; MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOPONTIN; THROMBOSPONDIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; HISTOPATHOLOGY; HYPERCHOLESTEROLEMIA; MICROVASCULAR REMODELING; MOUSE; NEPHRITIS; NONHUMAN; PROTEIN EXPRESSION; RENAL PROTECTION; WESTERN BLOTTING;

ANIMALS; APOLIPOPROTEINS E; APOPTOSIS; ATHEROSCLEROSIS; BLOTTING, WESTERN; DISEASE PROGRESSION; FEMALE; HYPERCHOLESTEROLEMIA; INFLAMMATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; KIDNEY DISEASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROVESSELS; NEOVASCULARIZATION, PATHOLOGIC;

MUS;

EID: 84865271368     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.07.010     Document Type: Article

References (33)

1. H.M. Amin, T.J. McDonnell, Y. Ma, Q. Lin, Y. Fujio, and K. Kunisada Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma Oncogene 23 2004 5426 5434
2. Y. Asou, S.R. Rittling, H. Yoshitake, K. Tsuji, K. Shinomiya, and A. Nifuji Osteopontin facilitates angiogenesis, accumulation of osteoclasts, and resorption in ectopic bone Endocrinology 142 2001 1325 1332
3. A.R. Bachar, L. Scheffer, A.S. Schroeder, H.K. Nakamura, L.J. Cobb, and Y.K. Oh Humanin is expressed in human vascular walls and has a cytoprotective effect against oxidized LDL-induced oxidative stress Cardiovasc Res 88 2010 360 366
4. M.D. Bentley, M. Rodriguez-Porcel, A. Lerman, M.H. Sarafov, J.C. Romero, and L.I. Pelaez Enhanced renal cortical vascularization in experimental hypercholesterolemia Kidney Int 61 2002 1056 1063
5. A.R. Chade, M. Rodriguez-Porcel, J.P. Grande, J.D. Krier, A. Lerman, and J.C. Romero Distinct renal injury in early atherosclerosis and renovascular disease Circulation 106 2002 1165 1171
6. A.R. Chade, M. Rodriguez-Porcel, J.P. Grande, X. Zhu, V. Sica, and C. Napoli Mechanisms of renal structural alterations in combined hypercholesterolemia and renal artery stenosis Arterioscler Thromb Vasc Biol 23 2003 1295 1301
7. A.R. Chade, J. Herrmann, X. Zhu, J.D. Krier, A. Lerman, and L.O. Lerman Effects of proteasome inhibition on the kidney in experimental hypercholesterolemia J Am Soc Nephrol 16 2005 1005 1012
8. A.R. Chade, A. Lerman, and L.O. Lerman Kidney in early atherosclerosis Hypertension 45 2005 1042 1049
9. A.R. Chade, X. Zhu, O.P. Mushin, C. Napoli, A. Lerman, and L.O. Lerman Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia FASEB J 20 2006 1706 1708
10. A.R. Chade, J.D. Krier, O. Galili, A. Lerman, and L.O. Lerman Role of renal cortical neovascularization in experimental hypercholesterolemia Hypertension 50 2007 729 736
11. A.J. Collins, S. Li, D.T. Gilbertson, J. Liu, S.C. Chen, and C.A. Herzog Chronic kidney disease and cardiovascular disease in the Medicare population Kidney Int Suppl 2003 S24 S31
12. A. Dandapat, C. Hu, L. Sun, and J.L. Mehta Small concentrations of oxLDL induce capillary tube formation from endothelial cells via LOX-1-dependent redox-sensitive pathway Arterioscler Thromb Vasc Biol 27 2007 2435 2442
13. B. Guo, D. Zhai, E. Cabezas, K. Welsh, S. Nouraini, and A.C. Satterthwait Humanin peptide suppresses apoptosis by interfering with Bax activation Nature 423 2003 456 461
14. Y. Hashimoto, T. Niikura, H. Tajima, T. Yasukawa, H. Sudo, and Y. Ito A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta Proc Natl Acad Sci U S A 98 2001 6336 6341
15. P.T. Hoang, P. Park, L.J. Cobb, V. Paharkova-Vatchkova, M. Hakimi, and P. Cohen The neurosurvival factor Humanin inhibits beta-cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonobese diabetic mice Metabolism 59 2010 343 349
16. M. Ikonen, B. Liu, Y. Hashimoto, L. Ma, K.W. Lee, and T. Niikura Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis Proc Natl Acad Sci U S A 100 2003 13042 13047
17. G. Ligresti, A.C. Aplin, P. Zorzi, A. Morishita, and R.F. Nicosia Macrophage-derived tumor necrosis factor-alpha is an early component of the molecular cascade leading to angiogenesis in response to aortic injury Arterioscler Thromb Vasc Biol 31 2011 1151 1159
18. J. Miao, W. Zhang, R. Yin, R. Liu, C. Su, and G. Lei S14G-Humanin ameliorates Abeta25-35-induced behavioral deficits by reducing neuroinflammatory responses and apoptosis in mice Neuropeptides 42 2008 557 567
19. P.R. Moreno, K.R. Purushothaman, E. Zias, J. Sanz, and V. Fuster Neovascularization in human atherosclerosis Curr Mol Med 6 2006 457 477
20. K.S. Moulton, K. Vakili, D. Zurakowski, M. Soliman, C. Butterfield, and E. Sylvin Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis Proc Natl Acad Sci U S A 100 2003 4736 4741
21. B.P. Oberg, E. McMenamin, F.L. Lucas, E. McMonagle, J. Morrow, and T.A. Ikizler Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease Kidney Int 65 2004 1009 1016
22. Y.K. Oh, A.R. Bachar, D.G. Zacharias, S.G. Kim, J. Wan, and L.J. Cobb Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice Atherosclerosis 219 2011 65 73
23. A.S. Plump, J.D. Smith, T. Hayek, K. Aalto-Setala, A. Walsh, and J.G. Verstuyft Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells Cell 71 1992 343 353
24. R. Salcedo, M.L. Ponce, H.A. Young, K. Wasserman, J.M. Ward, and H.K. Kleinman Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression Blood 96 2000 34 40
25. L. Salomonsson, S. Pettersson, M.C. Englund, O. Wiklund, and B.G. Ohlsson Post-transcriptional regulation of VEGF expression by oxidised LDL in human macrophages Eur J Clin Invest 32 2002 767 774
26. M. Scatena, L. Liaw, and C.M. Giachelli Osteopontin: a multifunctional molecule regulating chronic inflammation and vascular disease Arterioscler Thromb Vasc Biol 27 2007 2302 2309
27. M.A. Sparks, K.K. Parsons, J. Stegbauer, S.B. Gurley, A. Vivekanandan-Giri, and C.N. Fortner Angiotensin II type 1A receptors in vascular smooth muscle cells do not influence aortic remodeling in hypertension Hypertension 57 2011 577 585
28. J. Wang, C. Ouyang, X. Chen, B. Fu, Y. Lu, and Q. Hong STAT3 inhibits apoptosis of human renal tubular epithelial cells induced by ATP depletion/recovery Nephron Exp Nephrol 108 2008 e11 e18
29. G. Wuerzner, M. Pruijm, M. Maillard, P. Bovet, C. Renaud, and M. Burnier Marked association between obesity and glomerular hyperfiltration: a cross-sectional study in an African population Am J Kidney Dis 56 2010 303 312
30. C.H. Yeh, H.S. Chiang, T.Y. Lai, and C.T. Chien Unilateral ureteral obstruction evokes renal tubular apoptosis via the enhanced oxidative stress and endoplasmic reticulum stress in the rat Neurourol Urodyn 30 2011 472 479
31. D.G. Zacharias, S.G. Kim, A.E. Massat, A.R. Bachar, Y.K. Oh, and J. Herrmann Humanin, a cytoprotective peptide, is expressed in carotid artherosclerotic plaques in humans PLoS One 7 2012 e31065
32. X.Y. Zhu, M. Rodriguez-Porcel, M.D. Bentley, A.R. Chade, V. Sica, and C. Napoli Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia Circulation 109 2004 2109 2115
33. X.Y. Zhu, A.R. Chade, J.D. Krier, E. Daghini, R. Lavi, and A. Guglielmotti The chemokine monocyte chemoattractant protein-1 contributes to renal dysfunction in swine renovascular hypertension J Hypertens 27 2009 2063 2073