-
1
-
-
33645401909
-
Skin barrier function and allergic risk
-
T.J. Hudson Skin barrier function and allergic risk Nat Genet 38 2006 399 400
-
(2006)
Nat Genet
, vol.38
, pp. 399-400
-
-
Hudson, T.J.1
-
2
-
-
66749163178
-
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming
-
P.G. Fallon, T. Sasaki, A. Sandilands, L.E. Campbell, S.P. Saunders, N.E. Mangan, J.J. Callanan, H. Kawasaki, A. Shiohama, A. Kubo, J.P. Sundberg, R.B. Presland, P. Fleckman, N. Shimizu, J. Kudoh, A.D. Irvine, M. Amagai, W.H. McLean A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming Nat Genet 41 2009 602 608
-
(2009)
Nat Genet
, vol.41
, pp. 602-608
-
-
Fallon, P.G.1
Sasaki, T.2
Sandilands, A.3
Campbell, L.E.4
Saunders, S.P.5
Mangan, N.E.6
Callanan, J.J.7
Kawasaki, H.8
Shiohama, A.9
Kubo, A.10
Sundberg, J.P.11
Presland, R.B.12
Fleckman, P.13
Shimizu, N.14
Kudoh, J.15
Irvine, A.D.16
Amagai, M.17
McLean, W.H.18
-
3
-
-
69349087273
-
Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens
-
T.C. Scharschmidt, M.Q. Man, Y. Hatano, D. Crumrine, R. Gunathilake, J.P. Sundberg, K.A. Silva, T.M. Mauro, M. Hupe, S. Cho, Y. Wu, A. Celli, M. Schmuth, K.R. Feingold, P.M. Elias Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens J Allergy Clin Immunol 124 2009 496 506 506 e491-496
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 496-506
-
-
Scharschmidt, T.C.1
Man, M.Q.2
Hatano, Y.3
Crumrine, D.4
Gunathilake, R.5
Sundberg, J.P.6
Silva, K.A.7
Mauro, T.M.8
Hupe, M.9
Cho, S.10
Wu, Y.11
Celli, A.12
Schmuth, M.13
Feingold, K.R.14
Elias, P.M.15
-
4
-
-
77952058742
-
Flaky tail mouse denotes human atopic dermatitis in the steady state and by topical application with Dermatophagoides pteronyssinus extract
-
C.S. Moniaga, G. Egawa, H. Kawasaki, M. Hara-Chikuma, T. Honda, H. Tanizaki, S. Nakajima, A. Otsuka, H. Matsuoka, A. Kubo, J. Sakabe, Y. Tokura, Y. Miyachi, M. Amagai, K. Kabashima Flaky tail mouse denotes human atopic dermatitis in the steady state and by topical application with Dermatophagoides pteronyssinus extract Am J Pathol 176 2010 2385 2393
-
(2010)
Am J Pathol
, vol.176
, pp. 2385-2393
-
-
Moniaga, C.S.1
Egawa, G.2
Kawasaki, H.3
Hara-Chikuma, M.4
Honda, T.5
Tanizaki, H.6
Nakajima, S.7
Otsuka, A.8
Matsuoka, H.9
Kubo, A.10
Sakabe, J.11
Tokura, Y.12
Miyachi, Y.13
Amagai, M.14
Kabashima, K.15
-
5
-
-
0027744129
-
Occludin: A novel integral membrane protein localizing at tight junctions
-
M. Furuse, T. Hirase, M. Itoh, A. Nagafuchi, S. Yonemura, S. Tsukita Occludin: a novel integral membrane protein localizing at tight junctions J Cell Biol 123 1993 1777 1788
-
(1993)
J Cell Biol
, vol.123
, pp. 1777-1788
-
-
Furuse, M.1
Hirase, T.2
Itoh, M.3
Nagafuchi, A.4
Yonemura, S.5
Tsukita, S.6
-
6
-
-
0032577975
-
Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
-
M. Furuse, K. Fujita, T. Hiiragi, K. Fujimoto, S. Tsukita Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin J Cell Biol 141 1998 1539 1550
-
(1998)
J Cell Biol
, vol.141
, pp. 1539-1550
-
-
Furuse, M.1
Fujita, K.2
Hiiragi, T.3
Fujimoto, K.4
Tsukita, S.5
-
7
-
-
0028799226
-
Tight junctions and the molecular basis for regulation of paracellular permeability
-
J.M. Anderson, C.M. Van Itallie Tight junctions and the molecular basis for regulation of paracellular permeability Am J Physiol 269 1995 G467 G475
-
(1995)
Am J Physiol
, vol.269
-
-
Anderson, J.M.1
Van Itallie, C.M.2
-
9
-
-
0027207967
-
The molecular organization of tight junctions
-
S. Citi The molecular organization of tight junctions J Cell Biol 121 1993 485 489
-
(1993)
J Cell Biol
, vol.121
, pp. 485-489
-
-
Citi, S.1
-
10
-
-
0242641571
-
E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles
-
P. Young, O. Boussadia, H. Halfter, R. Grose, P. Berger, D.P. Leone, H. Robenek, P. Charnay, R. Kemler, U. Suter E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles EMBO J 22 2003 5723 5733
-
(2003)
EMBO J
, vol.22
, pp. 5723-5733
-
-
Young, P.1
Boussadia, O.2
Halfter, H.3
Grose, R.4
Berger, P.5
Leone, D.P.6
Robenek, H.7
Charnay, P.8
Kemler, R.9
Suter, U.10
-
11
-
-
79952307688
-
Tight junction defects in patients with atopic dermatitis
-
A. De Benedetto, N.M. Rafaels, L.Y. McGirt, A.I. Ivanov, S.N. Georas, C. Cheadle, A.E. Berger, K. Zhang, S. Vidyasagar, T. Yoshida, M. Boguniewicz, T. Hata, L.C. Schneider, J.M. Hanifin, R.L. Gallo, N. Novak, S. Weidinger, T.H. Beaty, D.Y. Leung, K.C. Barnes, L.A. Beck Tight junction defects in patients with atopic dermatitis J Allergy Clin Immunol 127 2011 773-786e771-777
-
(2011)
J Allergy Clin Immunol
, vol.127
-
-
De Benedetto, A.1
Rafaels, N.M.2
McGirt, L.Y.3
Ivanov, A.I.4
Georas, S.N.5
Cheadle, C.6
Berger, A.E.7
Zhang, K.8
Vidyasagar, S.9
Yoshida, T.10
Boguniewicz, M.11
Hata, T.12
Schneider, L.C.13
Hanifin, J.M.14
Gallo, R.L.15
Novak, N.16
Weidinger, S.17
Beaty, T.H.18
Leung, D.Y.19
Barnes, K.C.20
Beck, L.A.21
more..
-
12
-
-
33244463813
-
Complex networks orchestrate epithelial-mesenchymal transitions
-
J.P. Thiery, J.P. Sleeman Complex networks orchestrate epithelial-mesenchymal transitions Nat Rev Mol Cell Biol 7 2006 131 142
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 131-142
-
-
Thiery, J.P.1
Sleeman, J.P.2
-
13
-
-
39149091017
-
Outside-in signaling through integrins and cadherins: A central mechanism to control epidermal growth and differentiation?
-
E.J. Muller, L. Williamson, C. Kolly, M.M. Suter Outside-in signaling through integrins and cadherins: a central mechanism to control epidermal growth and differentiation? J Invest Dermatol 128 2008 501 516
-
(2008)
J Invest Dermatol
, vol.128
, pp. 501-516
-
-
Muller, E.J.1
Williamson, L.2
Kolly, C.3
Suter, M.M.4
-
14
-
-
77956180402
-
SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress
-
S. Caito, S. Rajendrasozhan, S. Cook, S. Chung, H. Yao, A.E. Friedman, P.S. Brookes, I. Rahman SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress FASEB J 24 2010 3145 3159
-
(2010)
FASEB J
, vol.24
, pp. 3145-3159
-
-
Caito, S.1
Rajendrasozhan, S.2
Cook, S.3
Chung, S.4
Yao, H.5
Friedman, A.E.6
Brookes, P.S.7
Rahman, I.8
-
15
-
-
58149360793
-
SIRT1 promotes differentiation of normal human keratinocytes
-
G. Blander, A. Bhimavarapu, T. Mammone, D. Maes, K. Elliston, C. Reich, M.S. Matsui, L. Guarente, J.J. Loureiro SIRT1 promotes differentiation of normal human keratinocytes J Invest Dermatol 129 2009 41 49
-
(2009)
J Invest Dermatol
, vol.129
, pp. 41-49
-
-
Blander, G.1
Bhimavarapu, A.2
Mammone, T.3
Maes, D.4
Elliston, K.5
Reich, C.6
Matsui, M.S.7
Guarente, L.8
Loureiro, J.J.9
-
16
-
-
39149098125
-
Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6
-
B.E. Kim, D.Y. Leung, M. Boguniewicz, M.D. Howell Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6 Clin Immunol 126 2008 332 337
-
(2008)
Clin Immunol
, vol.126
, pp. 332-337
-
-
Kim, B.E.1
Leung, D.Y.2
Boguniewicz, M.3
Howell, M.D.4
-
17
-
-
35348891489
-
N-acetylcysteine protects melanocytes against oxidative stress/damage and delays onset of ultraviolet-induced melanoma in mice
-
M.A. Cotter, J. Thomas, P. Cassidy, K. Robinette, N. Jenkins, S.R. Florell, S. Leachman, W.E. Samlowski, D. Grossman N-acetylcysteine protects melanocytes against oxidative stress/damage and delays onset of ultraviolet-induced melanoma in mice Clin Cancer Res 13 2007 5952 5958
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5952-5958
-
-
Cotter, M.A.1
Thomas, J.2
Cassidy, P.3
Robinette, K.4
Jenkins, N.5
Florell, S.R.6
Leachman, S.7
Samlowski, W.E.8
Grossman, D.9
-
18
-
-
0023852747
-
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line
-
P. Boukamp, R.T. Petrussevska, D. Breitkreutz, J. Hornung, A. Markham, N.E. Fusenig Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line J Cell Biol 106 1988 761 771
-
(1988)
J Cell Biol
, vol.106
, pp. 761-771
-
-
Boukamp, P.1
Petrussevska, R.T.2
Breitkreutz, D.3
Hornung, J.4
Markham, A.5
Fusenig, N.E.6
-
19
-
-
77952341618
-
Activation of vascular endothelial growth factor receptor 2 in a cellular model of loricrin keratoderma
-
K. Yoneda, T. Demitsu, K. Nakai, T. Moriue, W. Ogawa, J. Igarashi, H. Kosaka, Y. Kubota Activation of vascular endothelial growth factor receptor 2 in a cellular model of loricrin keratoderma J Biol Chem 285 2010 16184 16194
-
(2010)
J Biol Chem
, vol.285
, pp. 16184-16194
-
-
Yoneda, K.1
Demitsu, T.2
Nakai, K.3
Moriue, T.4
Ogawa, W.5
Igarashi, J.6
Kosaka, H.7
Kubota, Y.8
-
20
-
-
0015340422
-
Two new mutations in linkage group XVI of the house mouse: Flaky tail and varitint-waddler-J
-
P.W. Lane Two new mutations in linkage group XVI of the house mouse Flaky tail and varitint-waddler-J J Hered 63 1972 135 140
-
(1972)
J Hered
, vol.63
, pp. 135-140
-
-
Lane, P.W.1
-
21
-
-
0034523633
-
Loss of normal profilaggrin and filaggrin in flaky tail (ft/ft) mice: An animal model for the filaggrin-deficient skin disease ichthyosis vulgaris
-
R.B. Presland, D. Boggess, S.P. Lewis, C. Hull, P. Fleckman, J.P. Sundberg Loss of normal profilaggrin and filaggrin in flaky tail (ft/ft) mice: an animal model for the filaggrin-deficient skin disease ichthyosis vulgaris J Invest Dermatol 115 2000 1072 1081
-
(2000)
J Invest Dermatol
, vol.115
, pp. 1072-1081
-
-
Presland, R.B.1
Boggess, D.2
Lewis, S.P.3
Hull, C.4
Fleckman, P.5
Sundberg, J.P.6
-
22
-
-
79956054080
-
TNF-alpha downregulates filaggrin and loricrin through c-Jun N-terminal kinase: Role for TNF-alpha antagonists to improve skin barrier
-
B.E. Kim, M.D. Howell, E. Guttman, P.M. Gilleaudeau, I.R. Cardinale, M. Boguniewicz, J.G. Krueger, D.Y. Leung TNF-alpha downregulates filaggrin and loricrin through c-Jun N-terminal kinase: role for TNF-alpha antagonists to improve skin barrier J Invest Dermatol 131 2011 1272 1279
-
(2011)
J Invest Dermatol
, vol.131
, pp. 1272-1279
-
-
Kim, B.E.1
Howell, M.D.2
Guttman, E.3
Gilleaudeau, P.M.4
Cardinale, I.R.5
Boguniewicz, M.6
Krueger, J.G.7
Leung, D.Y.8
-
23
-
-
79959249198
-
Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function
-
R. Gruber, P.M. Elias, D. Crumrine, T.K. Lin, J.M. Brandner, J.P. Hachem, R.B. Presland, P. Fleckman, A.R. Janecke, A. Sandilands, W.H. McLean, P.O. Fritsch, M. Mildner, E. Tschachler, M. Schmuth Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function Am J Pathol 178 2011 2252 2263
-
(2011)
Am J Pathol
, vol.178
, pp. 2252-2263
-
-
Gruber, R.1
Elias, P.M.2
Crumrine, D.3
Lin, T.K.4
Brandner, J.M.5
Hachem, J.P.6
Presland, R.B.7
Fleckman, P.8
Janecke, A.R.9
Sandilands, A.10
McLean, W.H.11
Fritsch, P.O.12
Mildner, M.13
Tschachler, E.14
Schmuth, M.15
-
24
-
-
27944482616
-
E-cadherin promotes EGFR-mediated cell differentiation and MUC5AC mucin expression in cultured human airway epithelial cells
-
S. Kim, A.J. Schein, J.A. Nadel E-cadherin promotes EGFR-mediated cell differentiation and MUC5AC mucin expression in cultured human airway epithelial cells Am J Physiol Lung Cell Mol Physiol 289 2005 L1049 L1060
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.289
-
-
Kim, S.1
Schein, A.J.2
Nadel, J.A.3
-
25
-
-
0034731148
-
Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation
-
S. Pece, J.S. Gutkind Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation J Biol Chem 275 2000 41227 41233
-
(2000)
J Biol Chem
, vol.275
, pp. 41227-41233
-
-
Pece, S.1
Gutkind, J.S.2
-
26
-
-
77955867229
-
Thiol redox transitions in cell signaling: A lesson from N-acetylcysteine
-
T. Parasassi, R. Brunelli, G. Costa, M. De Spirito, E. Krasnowska, T. Lundeberg, E. Pittaluga, F. Ursini Thiol redox transitions in cell signaling: a lesson from N-acetylcysteine ScientificWorldJournal 10 2010 1192 1202
-
(2010)
ScientificWorldJournal
, vol.10
, pp. 1192-1202
-
-
Parasassi, T.1
Brunelli, R.2
Costa, G.3
De Spirito, M.4
Krasnowska, E.5
Lundeberg, T.6
Pittaluga, E.7
Ursini, F.8
-
27
-
-
0035066130
-
Thiols decrease cytokine levels and down-regulate the expression of CD30 on human allergen-specific T helper (Th) 0 and Th2 cells
-
A. Bengtsson, M. Lundberg, J. Avila-Carino, G. Jacobsson, A. Holmgren, A. Scheynius Thiols decrease cytokine levels and down-regulate the expression of CD30 on human allergen-specific T helper (Th) 0 and Th2 cells Clin Exp Immunol 123 2001 350 360
-
(2001)
Clin Exp Immunol
, vol.123
, pp. 350-360
-
-
Bengtsson, A.1
Lundberg, M.2
Avila-Carino, J.3
Jacobsson, G.4
Holmgren, A.5
Scheynius, A.6
-
28
-
-
0345685437
-
Topical N-acetylcysteine for lamellar ichthyosis
-
P. Redondo, A. Bauza Topical N-acetylcysteine for lamellar ichthyosis Lancet 354 1999 1880
-
(1999)
Lancet
, vol.354
, pp. 1880
-
-
Redondo, P.1
Bauza, A.2
|