Are biological actions of neurokinin A in the adult brain mediated by a cross-talk between the NK1 and NK2 receptors?

Neuropharmacology

Volumn 63, Issue 6, 2012, Pages 958-965

  Tauer, Ulrike ^a   Zhao, Yi ^a   Hunt, Steven P ^b   Culman, Juraj ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Brain; Mouse; Neurokinin A; NK1 NK2 receptor interaction

Indexed keywords

2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; NEUROKININ 1 RECEPTOR; NEUROKININ 2 RECEPTOR; NEUROKININ 2 RECEPTOR AGONIST; NEUROKININ 3 RECEPTOR; NEUROKININ A; NEUROKININ A [4-10][10 NORLEUCINE]; NEUROKININ A [4-10][8 BETA ALANINE]; OSANETANT; SENKTIDE; SR 48958; SUBSTANCE P; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GROOMING; MALE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; RECEPTOR UPREGULATION; WILD TYPE;

ANIMALS; BEHAVIOR, ANIMAL; BENZAMIDES; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; GROOMING; INJECTIONS, INTRAVENTRICULAR; ISOINDOLES; MALE; MICE; MICE, KNOCKOUT; NEUROKININ A; PEPTIDE FRAGMENTS; PIPERIDINES; RECEPTOR CROSS-TALK; RECEPTORS, NEUROKININ-1; RECEPTORS, NEUROKININ-2; RECEPTORS, NEUROKININ-3; STEREOISOMERISM; SUBSTANCE P;

EID: 84865255047     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.06.041     Document Type: Article

References (39)

1. I.D. Alves, D. Delaroche, B. Mouillac, Z. Salamon, G. Tollin, V.J. Hruby, S. Lavielle, and S. Sagan The two NK-1 binding sites correspond to distinct, independent, and non-interconvertible receptor conformational states as confirmed by plasmon-waveguide resonance spectroscopy Biochemistry 45 2006 5309 5318
2. J.C. Beaujouan, M. Saffroy, Y. Torrens, and J. Glowinski Different subtypes of tachykinin NK(1) receptor binding sites are present in the rat brain J. Neurochem. 75 2000 1015 1026 (Pubitemid 30660489)
3. K.C. Berridge, J.C. Fentress, and H. Parr Natural syntax rules control action sequence of rats Behav. Brain Res. 23 1987 59 68 (Pubitemid 17234532)
4. N. Bhogal, D. Donnelly, and J.B. Findlay The ligand binding site of the neurokinin 2 receptor. Site-directed mutagenesis and identification of neurokinin A binding residues in the human neurokinin 2 receptor J. Biol. Chem. 269 1994 27269 27274
5. R. Couture, P. Picard, P. Poulat, and A. Pratt Characterization of the tachykinin receptors involved in spinal and supraspinal cardiovascular regulation Can. J. Physiol. Pharmacol. 73 1995 892 902
6. H.C. Cromwell, and K.C. Berridge Implementation of action sequences by a neostriatal site: a lesion mapping study of grooming syntax J. Neurosci. 16 1996 3444 3458 (Pubitemid 26142374)
7. J. Culman, C. Tschöpe, N. Jost, K. Itoi, and T. Unger Substance P and neurokinin A induced desensitization to cardiovascular and behavioral effects: evidence for the involvement of different tachykinin receptors Brain Res. 625 1993 75 83 (Pubitemid 23285445)
8. J. Culman, B. Wiegand, H. Spitznagel, S. Klee, and T. Unger Effects of the tachykinin NK1 receptor antagonist, RP 67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B Br. J. Pharmacol. 114 1995 1310 1316
9. C. De Felipe, J.F. Herrero, J.A. O'Brien, J.A. Palmer, C.A. Doyle, A.J. Smith, J.M. Laird, C. Belmonte, F. Cervero, and S.P. Hunt Altered nociception, analgesia and aggression in mice lacking the receptor for substance P Nature 392 1998 394 397 (Pubitemid 28168736)
10. X. Emonds-Alt, P. Vilain, P. Goulaouic, V. Proietto, D. Van Broeck, C. Advenier, E. Naline, G. Neliat, G. Le Fur, and J.C. Brelire A potent and selective non-peptide antagonist of the neurokinin A (NK2) receptor Life Sci. 50 1992 PL101 PL106
11. X. Emonds-Alt, D. Bichon, J.P. Ducoux, M. Heaulme, B. Miloux, M. Poncelet, V. Proietto, D. Van Broeck, P. Vilain, and G. Neliat SR 142801, the first potent non-peptide antagonist of the tachykinin NK3 receptor Life Sci. 56 1995 PL27 PL32
12. T.M. Fong, H. Yu, R.R. Huang, and C.D. Strader The extracellular domain of the neurokinin-1 receptor is required for high-affinity binding of peptides Biochemistry 31 1992 11806 11811
13. T.M. Fong, H. Yu, M.A. Cascieri, D. Underwood, C.J. Swain, and C.D. Strader Interaction of glutamine 165 in the fourth transmembrane segment of the human neurokinin-1 receptor with quinuclidine antagonists J. Biol. Chem. 269 1994 14957 14961 (Pubitemid 24198334)
14. T.M. Fong, R.C. Huang, H. Yu, C.J. Swain, D. Underwood, M.A. Cascieri, and C.D. Strader Mutational analysis of neurokinin receptor function Can. J. Physiol. Pharmacol. 73 1995 860 865
15. C. Garret, A. Carruette, V. Fardin, S. Moussaoui, J.F. Peyronel, J.C. Blanchard, and P.M. Laduron Pharmacological properties of a potent and selective nonpeptide substance P antagonist Proc. Natl. Acad. Sci. U. S. A. 88 1991 10208 10212 (Pubitemid 21915804)
16. U. Gether, Y. Yokota, X. Emonds-Alt, J.C. Brelire, J.A. Lowe 3rd, R.M. Snider, S. Nakanishi, and T.W. Schwartz Two nonpeptide tachykinin antagonists act through epitopes on corresponding segments of the NK1 and NK2 receptors Proc. Natl. Acad. Sci. U. S. A. 90 1993 6194 6198 (Pubitemid 23191481)
17. H. Hastrup, and T.W. Schwartz Septide and neurokinin A are high-affinity ligands on the NK-1 receptor: evidence from homologous versus heterologous binding analysis FEBS Lett. 399 1996 264 266 (Pubitemid 26426863)
18. T. Höckfelt, T. Kuteeva, D. Stanic, and. Ljungdahl The histochemistry of tachykinin system in the brain P. Holzer, Tachykinins. Handbook of Experimental Pharmacology 2004 Springer-Verlag Berlin, Heidelberg 63 120
19. R.R. Huang, H. Yu, C.D. Strader, and T.M. Fong Interaction of substance P with the second and seventh transmembrane domains of the neurokinin-1 receptor Biochemistry 33 1994 3007 3013 (Pubitemid 24103362)
20. C.J. Jensen, N.P. Gerard, T.W. Schwartz, and U. Gether The species selectivity of chemically distinct tachykinin nonpeptide antagonists is dependent on common divergent residues of the rat and human neurokinin-1 receptors Mol. Pharmacol. 45 1994 294 299 (Pubitemid 24063083)
21. M. Keller, S. Montgomery, W. Ball, M. Morrison, D. Snavely, G. Liu, R. Hargreaves, J. Hietala, C. Lines, K. Beebe, and S. Reines Lack of efficacy of the substance p (neurokinin1 receptor) antagonist aprepitant in the treatment of major depressive disorder Biol. Psychiatry 59 2006 216 223 (Pubitemid 43208967)
22. M.S. Kramer, N. Cutler, J. Feighner, R. Shrivastava, J. Carman, J.J. Sramek, S.A. Reines, G. Liu, D. Snavely, E. Wyatt-Knowles, J.J. Hale, S.G. Mills, M. MacCoss, C.J. Swain, T. Harrison, R.G. Hill, F. Hefti, E.M. Scolnick, M.A. Cascieri, G.G. Chicchi, S. Sadowski, A.R. Williams, L. Hewson, D. Smith, E.J. Carlson, R.J. Hargreaves, and N.M. Rupniak Distinct mechanism for antidepressant activity by blockade of central substance P receptors Science 281 1998 1640 1645 (Pubitemid 28435572)
23. C. Louis, J. Stemmelin, D. Boulay, O. Bergis, C. Cohen, and G. Griebel Additional evidence for anxiolytic- and antidepressant-like activities of saredutant (SR48968), an antagonist at the neurokinin-2 receptor in various rodent-models Pharmacol. Biochem. Behav. 89 2008 36 45
24. C.A. Maggi, and T.W. Schwartz The dual nature of the tachykinin NK1 receptor Trends Pharmacol. Sci. 18 1997 351 355 (Pubitemid 27435057)
25. C.A. Maggi, R. Patacchini, S. Giuliani, and A. Giachetti In vivo and in vitro pharmacology of SR 48,968, a non-peptide tachykinin NK2 receptor antagonist Eur. J. Pharmacol. 234 1993 83 90 (Pubitemid 23093408)
26. P. Picard, D. Regoli, and R. Couture Cardiovascular and behavioural effects of centrally administered tachykinins in the rat: characterization of receptors with selective antagonists Br. J. Pharmacol. 112 1994 240 249 (Pubitemid 24151733)
27. L. Pradier, J. Ménager, J. Le Guern, M.D. Bock, E. Heuillet, V. Fardin, C. Garret, A. Doble, and J.F. Mayaux Septide: an agonist for the NK1 receptor acting at a site distinct from substance P Mol. Pharmacol. 45 1994 287 293 (Pubitemid 24063082)
28. S.C. Prinster, C. Hague, and R.A. Hall Heterodimerization of g protein-coupled receptors: specificity and functional significance Pharmacol. Rev. 57 2005 289 298 (Pubitemid 41196951)
29. E. Ratti, K. Bellew, P. Bettica, H. Bryson, S. Zamuner, G. Archer, L. Squassante, A. Bye, D. Trist, K.R. Krishnan, and S. Fernandes Results from 2 randomized, double-blind, placebo-controlled studies of the novel NK1 receptor antagonist casopitant in patients with major depressive disorder J. Clin. Psychopharmacol. 31 2011 727 733
30. S. Ravard, J. Betschart, V. Fardin, O. Flamand, and J.C. Blanchard Differential ability of tachykinin NK-1 and NK-2 agonists to produce scratching and grooming behaviours in mice Brain Res. 651 1994 199 208 (Pubitemid 24222868)
31. D. Regoli, A. Boudon, and J.L. Fauchére Receptors and antagonists for substance P and related peptides Pharmacol. Rev. 46 1994 551 599
32. M. Saffroy, Y. Torrens, J. Glowinski, and J.C. Beaujouan Presence of NK2 binding sites in the rat brain J. Neurochem. 79 2001 985 996 (Pubitemid 33117077)
33. M. Saffroy, Y. Torrens, J. Glowinski, and J.C. Beaujouan Autoradiographic distribution of tachykinin NK2 binding sites in the rat brain: comparison with NK1 and NK3 binding sites Neuroscience 116 2003 761 773 (Pubitemid 36160572)
34. S. Sagan, G. Chassaing, L. Pradier, and S. Lavielle Tachykinin peptides affect differently the second messenger pathways after binding to CHO-expressed human NK-1 receptors J. Pharmacol. Exp. Ther. 276 1996 1039 1048 (Pubitemid 3041415)
35. R. Steinberg, N. Marco, B. Voutsinos, M. Bensaid, D. Rodier, J. Souilhac, R. Alonso, F. Oury-Donat, G. Le Fur, and P. Soubrie Expression and presence of septal neurokinin-2 receptors controlling hippocampal acetylcholine release during sensory stimulation in rat Eur. J. Neurosci. 10 1998 2337 2345 (Pubitemid 28302336)
36. R. Steinberg, R. Alonso, G. Griebel, L. Bert, M. Jung, F. Oury-Donat, M. Poncelet, C. Gueudet, C. Desvignes, G. Le Fur, and P. Soubrié Selective blockade of neurokinin-2 receptors produces antidepressant-like effects associated with reduced corticotropin-releasing factor function J. Pharmacol. Exp. Ther. 299 2001 449 458 (Pubitemid 32979655)
37. C. Tschöpe, P. Picard, J. Culman, A. Prat, K. Itoi, D. Regoli, T. Unger, and R. Couture Use of selective antagonists to dissociate the central cardiovascular and behavioural effects of tachykinins on NK1 and NK2 receptors in the rat Br. J. Pharmacol. 107 1992 750 755
38. A. Wijkhuisen, M.A. Sagot, Y. Frobert, C. Créminon, J. Grassi, D. Boquet, and J.Y. Couraud Identification in the NK1 tachykinin receptor of a domain involved in recognition of neurokinin A and septide but not of substance P FEBS Lett. 447 1999 155 159 (Pubitemid 29146077)
39. Y. Yokota, C. Akazawa, H. Ohkubo, and S. Nakanishi Delineation of structural domains involved in the subtype specificity of tachykinin receptors through chimeric formation of substance P/substance K receptors EMBO J. 11 1992 3585 3591