The two NK-1 binding sites correspond to distinct, independent, and non-interconvertible receptor conformational states as confirmed by plasmon-waveguide resonance spectroscopy

Biochemistry

Volumn 45, Issue 16, 2006, Pages 5309-5318

  Alves, Isabel D ^a,b,c   Delaroche, Diane ^c,d   Mouillac, Bernard ^e   Salamon, Zdzislaw ^a   Tollin, Gordon ^a,b   Hruby, Victor J ^a,b   Lavielle, Solange ^c,d   Sagan, Sandrine ^c,d  

^a UNIVERSITY OF ARIZONA   (United States)

^b University of Arizona   (United States)

^c SORBONNE UNIVERSITÉ   (France)

^d CNRS   (France)

^e INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOTROPY; ENZYMES; LIPIDS; MEASUREMENT THEORY; MOLECULAR STRUCTURE; SPECTROSCOPIC ANALYSIS;

HEPTAPEPTIDE ANALOGUES; LIGAND-RECEPTORS; WAVEGUIDE RESONANCE SPECTROSCOPY;

BIOCHEMISTRY;

ADENYLATE CYCLASE; HEXAPEPTIDE; NEUROKININ 1 RECEPTOR; NEUROKININ 2 RECEPTOR; NEUROKININ A; PHOSPHOLIPASE C; SUBSTANCE P; SUBSTANCE P DERIVATIVE;

ANIMAL CELL; ANISOTROPY; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; LIGAND BINDING; LIPID BILAYER; NONHUMAN; PLASMON WAVEGUIDE RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR BINDING; SPECTROSCOPY; THERMODYNAMICS;

ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; GENE EXPRESSION; HUMANS; LIGANDS; PROTEIN CONFORMATION; RECEPTORS, NEUROKININ-1; SURFACE PLASMON RESONANCE;

ANIMALIA;

EID: 33645990891     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi052586d     Document Type: Article

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