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Volumn , Issue , 2012, Pages 115-128

Alfalfa the bountiful leading crop of all times' ecologies: Emerging biopharm and medicinal implications

Author keywords

Alfalfa; Biopharming; Health; Medicine; Pharmaceutical; Plant; Protein; Seed

Indexed keywords


EID: 84865243798     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (1)

References (44)
  • 2
    • 1542367699 scopus 로고    scopus 로고
    • Monoclonal C5-1 antibody produced in transgenic alfalfa plants exhibits a N-glycosylation that is homogenous and suitable for glyco-engineering into human-compatible structures
    • Doi: 10.1046/j.1467-7652.2003.00041.x
    • Bardor, M., Loutelier-Bourhis, C., Paccalet, T., Cosette, P., Fitchette, A-C., Vézina, L-P., Trépanier, S., Dargis, M., Lemieux, R., Loïc Faye, C-L. & Lerouge, P. (2003). Monoclonal C5-1 antibody produced in transgenic alfalfa plants exhibits a N-glycosylation that is homogenous and suitable for glyco-engineering into human-compatible structures. Plant Biotechnol. J. 1, 451-462. Doi: 10.1046/j.1467-7652.2003.00041.x.
    • (2003) Plant Biotechnol. J. , vol.1 , pp. 451-462
    • Bardor, M.1    Loutelier-Bourhis, C.2    Paccalet, T.3    Cosette, P.4    Fitchette, A.-C.5    Vézina, L.-P.6    Trépanier, S.7    Dargis, M.8    Lemieux, R.9    Loïc Faye, C.-L.10    Lerouge, P.11
  • 3
    • 0001081886 scopus 로고
    • The expression of a nopaline synthase - human growth hormone chimaeric gene in transformed tobacco and sunflower callus tissue
    • Barta, A., Sommergruber, K., Thompson, D. (1986). The expression of a nopaline synthase - human growth hormone chimaeric gene in transformed tobacco and sunflower callus tissue Plant Mol. Biol. 6 (5), 347-357.
    • (1986) Plant Mol Biol. , vol.6 , Issue.5 , pp. 347-357
    • Barta, A.1    Sommergruber, K.2    Thompson, D.3
  • 5
    • 0028821555 scopus 로고
    • Changes in protein methylation associated with the elicitation response in cell cultures of alfalfa (Medicago sativa L.)
    • Daniell, T. & Edwards, R. (1995). Changes in protein methylation associated with the elicitation response in cell cultures of alfalfa (Medicago sativa L.). FEBS Lett. 360, 57-61.
    • (1995) FEBS Lett. , vol.360 , pp. 57-61
    • Daniell, T.1    Edwards, R.2
  • 6
    • 25644454549 scopus 로고    scopus 로고
    • Efficient and Reliable Production of Pharmaceuticals in Alfalfa
    • Edited by Rainer Fischer, Stefan Schillberg. WILEY-VCH Verlag GmbH & Co. KGaA,Weinheim
    • D'Aoust, M-A., Lerouge, P., Busse, U., Bilodeau, P., Trépanier, S., Gomord, V., Faye, L. & Vézina, L-P. (2004). Efficient and Reliable Production of Pharmaceuticals in Alfalfa. Molecular Farming. Edited by Rainer Fischer, Stefan Schillberg. WILEY-VCH Verlag GmbH & Co. KGaA,Weinheim.
    • (2004) Molecular Farming
    • D'Aoust, M.-A.1    Lerouge, P.2    Busse, U.3    Bilodeau, P.4    Trépanier, S.5    Gomord, V.6    Faye, L.7    Vézina, L.-P.8
  • 7
    • 0028083496 scopus 로고
    • Effect of plant genotype on the transformation of cultivated alfalfa (Medicago sativa) by Agrobacterium tumefaciens
    • Du S., Erickon L., Bowley S. (1994). Effect of plant genotype on the transformation of cultivated alfalfa (Medicago sativa) by Agrobacterium tumefaciens Plant Cell Rep., 13(6), 330-334.
    • (1994) Plant Cell Rep. , vol.13 , Issue.6 , pp. 330-334
    • Du, S.1    Erickon, L.2    Bowley, S.3
  • 8
    • 14744305980 scopus 로고    scopus 로고
    • Development of transgenic alfalfa plants containing the foot and mouth disease virus structural polyprotein gene P1 and its utilization as an experimental immunogen
    • Dus Santos, M. J., Carrillo, C., Ardila, F., Rios, R. D. (2005). Development of transgenic alfalfa plants containing the foot and mouth disease virus structural polyprotein gene P1 and its utilization as an experimental immunogen. Vaccine 23, 1838-1843.
    • (2005) Vaccine , vol.23 , pp. 1838-1843
    • Dus Santos, M.J.1    Carrillo, C.2    Ardila, F.3    Rios, R.D.4
  • 9
    • 0033667765 scopus 로고    scopus 로고
    • Molecular farming of pharmaceutical proteins
    • Fischer, R. & Emans, N. (2000). Molecular farming of pharmaceutical proteins Transgenic Res. 9 (4-5), 279-299.
    • (2000) Transgenic Res. , vol.9 , Issue.4-5 , pp. 279-299
    • Fischer, R.1    Emans, N.2
  • 11
    • 0034833829 scopus 로고    scopus 로고
    • Nutritional and health benefits of soy proteins
    • Friedman, M. & Brandon, D. L. (2001). Nutritional and health benefits of soy proteins. J. Agric. Food Chem. 49 (3), 1069-1086.
    • (2001) J. Agric. Food Chem. , vol.49 , Issue.3 , pp. 1069-1086
    • Friedman, M.1    Brandon, D.L.2
  • 13
    • 33645742380 scopus 로고    scopus 로고
    • Research Advances on Transgenic Plant Vaccines
    • HAN, M., SU, T., ZU, Y-G. & AN, Z-G. (2006). Research Advances on Transgenic Plant Vaccines. Acta Genetica Sinica. 33, 285-293.
    • (2006) Acta Genetica Sinica. , vol.33 , pp. 285-293
    • Han, M.1    Su, T.2    Zu, Y.-G.3    An, Z.-G.4
  • 14
    • 0025715923 scopus 로고
    • Antibodies produced in plants
    • Hiatt A. (1990). Antibodies produced in plants. Nature, 344, 469-470.
    • (1990) Nature , vol.344 , pp. 469-470
    • Hiatt, A.1
  • 15
    • 84865270648 scopus 로고    scopus 로고
    • Production of biopharmaceuticals, antibodies, and edible vaccines in transgenic plants
    • Jelaska, S., Mihaljevic, S. & Bauer, N. (2005). Production of biopharmaceuticals, antibodies, and edible vaccines in transgenic plants. Cur. Stud. Biotechnol. 5, 121-127.
    • (2005) Cur. Stud. Biotechnol. , vol.5 , pp. 121-127
    • Jelaska, S.1    Mihaljevic, S.2    Bauer, N.3
  • 16
    • 0027502467 scopus 로고
    • Functional Cooperation among Human IgG-Specific Murine Monoclonal Antibodies for the Detection of Weak Blood Group Antibodies in Routine Agglutination Tests
    • Laurent, M. St., Marcil, A., Verrette, S. et al. (1993). Functional Cooperation among Human IgG-Specific Murine Monoclonal Antibodies for the Detection of Weak Blood Group Antibodies in Routine Agglutination Tests. Vox. Sang. 64 (2), 99-105.
    • (1993) Vox. Sang. , vol.64 , Issue.2 , pp. 99-105
    • Laurent, M.S.1    Marcil, A.2    Verrette, S.3
  • 18
    • 0000452573 scopus 로고
    • Expression and characterization of human lactoferrin in yeast Saccharomyces cerevisiae
    • Liang Q., Richardson T. (1993). Expression and characterization of human lactoferrin in yeast Saccharomyces cerevisiae. J. Agric Food Chem. 41, 1800-1807.
    • (1993) J. Agric Food Chem. , vol.41 , pp. 1800-1807
    • Liang, Q.1    Richardson, T.2
  • 19
    • 0032103849 scopus 로고    scopus 로고
    • Selection of biologically active human interleukin-2 and interleukin-4 from genetically modified tobacco cells in suspension culture
    • Magnuson N.S., Linzmaier P.M., Reeves R., An G., HayGlas K., Lee J.M. (1998). Selection of biologically active human interleukin-2 and interleukin-4 from genetically modified tobacco cells in suspension culture. Protein Expr. Purif., 13, 45-52.
    • (1998) Protein Expr. Purif. , vol.13 , pp. 45-52
    • Magnuson, N.S.1    Linzmaier, P.M.2    Reeves, R.3    An, G.4    HayGlas, K.5    Lee, J.M.6
  • 21
    • 85013983365 scopus 로고    scopus 로고
    • Medicago Inc. Product development
    • Medicago Inc. Product development. (2008). http://www.medicago.com/en/product/.
    • (2008)
  • 24
    • 1642563969 scopus 로고    scopus 로고
    • On risk and plant-based biopharmaceuticals
    • Peterson, R. K. & Arntzen, C. J. (2004). On risk and plant-based biopharmaceuticals. Trends Biotechnol. 22, 64-66.
    • (2004) Trends Biotechnol. , vol.22 , pp. 64-66
    • Peterson, R.K.1    Arntzen, C.J.2
  • 25
    • 84989141866 scopus 로고
    • Transformation of Medicago sativa L Using a Ti Plasmid Derived Vector
    • Pezzotti M., Pupilli F., Damiani F., Arcioni S. (1991). Transformation of Medicago sativa L. Using a Ti Plasmid Derived Vector. Plant Breeding, 106, 39-46.
    • (1991) Plant Breeding , vol.106 , pp. 39-46
    • Pezzotti, M.1    Pupilli, F.2    Damiani, F.3    Arcioni, S.4
  • 26
    • 0023064090 scopus 로고
    • The chemistry and biological significance of saponins in foods and feedingstuffs
    • Price, K. R., Johnson, I. T. & Fenwick, G. R. (1987) The chemistry and biological significance of saponins in foods and feedingstuffs. CRC Grit Rev Food Sci Nutr 26, 27-135.
    • (1987) CRC Grit Rev Food Sci Nutr , vol.26 , pp. 27-135
    • Price, K.R.1    Johnson, I.T.2    Fenwick, G.R.3
  • 27
    • 25644449032 scopus 로고    scopus 로고
    • Glycosylation variations with expression systems and their impact on biological activity of therapeutic immunoglobulins
    • April
    • Raju, T. S. (2003). Glycosylation variations with expression systems and their impact on biological activity of therapeutic immunoglobulins. BioProcess Int. April, 44-52.
    • (2003) BioProcess Int. , pp. 44-52
    • Raju, T.S.1
  • 28
    • 0028876822 scopus 로고
    • Saponins as anticarcinogens
    • Rao, A. V. & Sung, M-K. (1995). Saponins as anticarcinogens. J. Nutr. 125, 7178-7248.
    • (1995) J. Nutr. , vol.125 , pp. 7178-7248
    • Rao, A.V.1    Sung, M.-K.2
  • 29
    • 33646193336 scopus 로고    scopus 로고
    • Plant-made vaccines: biotechnology and immunology in animal health
    • Rice, J., Ainley, W. M. & Shewen, P. (2005). Plant-made vaccines: biotechnology and immunology in animal health. Anim. Health Res. Rev. 6, 199-209.
    • (2005) Anim. Health Res. Rev. , vol.6 , pp. 199-209
    • Rice, J.1    Ainley, W.M.2    Shewen, P.3
  • 30
    • 58149112262 scopus 로고    scopus 로고
    • Plant-produced vaccines: promise and reality
    • Rybicki, E. P. (2009). Plant-produced vaccines: promise and reality. Drug Discov. Today 14, 16-24.
    • (2009) Drug Discov. Today , vol.14 , pp. 16-24
    • Rybicki, E.P.1
  • 32
    • 0001033145 scopus 로고
    • Effect of eight dietary proteins and their amino acid content on serum, hepatic and fecal steroids in the rat
    • Sautier, C., Flament, C., Doucet, C. & Suquet, J. P. (1986). Effect of eight dietary proteins and their amino acid content on serum, hepatic and fecal steroids in the rat. Nutr. Rep. Int. 34, 1051-1059.
    • (1986) Nutr. Rep. Int. , vol.34 , pp. 1051-1059
    • Sautier, C.1    Flament, C.2    Doucet, C.3    Suquet, J.P.4
  • 33
    • 33947321425 scopus 로고    scopus 로고
    • Pharma-Planta: Road testing the developing regulatory guidelines for plant-made pharmaceuticals
    • DOI 10.1007/s11248-007-9074-2
    • Sparrow, P. A. C., Irwin, J. A., Dale, P. J., Twyman, R. M. & Ma, J. K. C. (2007). Pharma-Planta: Road testing the developing regulatory guidelines for plant-made pharmaceuticals. Transgen. Res. DOI 10.1007/s11248-007-9074-2
    • (2007) Transgen. Res.
    • Sparrow, P.A.C.1    Irwin, J.A.2    Dale, P.J.3    Twyman, R.M.4    Ma, J.K.C.5
  • 34
    • 0036355659 scopus 로고    scopus 로고
    • Practical considerations for pharmaceutical antibody production in different crop systems
    • Stoger, Sack, M., Perrin, Y. et al. (2002). Practical considerations for pharmaceutical antibody production in different crop systems. Mol. Breeding 9 (3), 149-158.
    • (2002) Mol. Breeding , vol.9 , Issue.3 , pp. 149-158
    • Stoger Sack, M.1    Perrin, Y.2
  • 35
    • 26844451777 scopus 로고    scopus 로고
    • Genetic modification of alfalfa (Medicago Sativa L.) for quality improvement and production of novel compounds
    • Eq. 19/2005 20th Anniversary AgroBioInstitute - R&D Special Issue
    • Vlahova, M., Stefanova, G., Petkov, P., Barbulova, A., Petkova, D., Kalushkov, P. & Atanassov, A. (2005). Genetic modification of alfalfa (Medicago Sativa L.) for quality improvement and production of novel compounds. Biotechnol. & Biotechnol. Eq. 19/2005 20th Anniversary AgroBioInstitute - R&D Special Issue.
    • (2005) Biotechnol. & Biotechnol
    • Vlahova, M.1    Stefanova, G.2    Petkov, P.3    Barbulova, A.4    Petkova, D.5    Kalushkov, P.6    Atanassov, A.7
  • 37
    • 31544476553 scopus 로고    scopus 로고
    • Mucosal immunization using recombinant plant-based oral vaccines
    • Streatfield, S. J. (2006). Mucosal immunization using recombinant plant-based oral vaccines. Methods 38, 150-157.
    • (2006) Methods , vol.38 , pp. 150-157
    • Streatfield, S.J.1
  • 38
    • 85031427579 scopus 로고    scopus 로고
    • Molecular Farming
    • (J.P Toutant, Balazs, Eds.), La grande Motte, France, 3-6 September
    • Tuboly T., Yu W., Baily A., Erickson L., Nagy E. (2000). In: Molecular Farming, (J.P. Toutant, Balazs, Eds.), Proceedings of the OECD Workshop, La grande Motte, France, 3-6 September 2000, 239-248.
    • (2000) Proceedings of the OECD Workshop , vol.2000 , pp. 239-248
    • Tuboly, T.1    Yu, W.2    Baily, A.3    Erickson, L.4    Nagy, E.5
  • 39
    • 0038066356 scopus 로고    scopus 로고
    • Plant cell factories and mucosal vaccines
    • Walmsley, A. M. & Arntzen, C. J. (2003). Plant cell factories and mucosal vaccines. Cur. Opin. Biotechnol. 14, 145-150.
    • (2003) Cur. Opin. Biotechnol. , vol.14 , pp. 145-150
    • Walmsley, A.M.1    Arntzen, C.J.2
  • 43
    • 2442625762 scopus 로고    scopus 로고
    • The plant vesicular transport engineering for production of useful recombinant proteins
    • Yoshida, K., Matsui, T. & Shinmyo, A. (2004). The plant vesicular transport engineering for production of useful recombinant proteins. J. Mol. Catal. B-Enzym, 28, 167-171.
    • (2004) J. Mol. Catal. B-Enzym , vol.28 , pp. 167-171
    • Yoshida, K.1    Matsui, T.2    Shinmyo, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.