메뉴 건너뛰기




Volumn 21, Issue 8, 2011, Pages 216-220

The Role of HCN Channels in Ventricular Repolarization

Author keywords

[No Author keywords available]

Indexed keywords

HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

EID: 84865190764     PISSN: 10501738     EISSN: 18732615     Source Type: Journal    
DOI: 10.1016/j.tcm.2012.05.013     Document Type: Review
Times cited : (21)

References (32)
  • 1
    • 67749116532 scopus 로고    scopus 로고
    • Control of heart rate by cAMP sensitivity of HCN channels
    • Alig J., Marger L., Mesirca P., et al. Control of heart rate by cAMP sensitivity of HCN channels. Proc Natl Acad Sci U S A 2009, 106:12189-12194.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12189-12194
    • Alig, J.1    Marger, L.2    Mesirca, P.3
  • 2
    • 0036021103 scopus 로고    scopus 로고
    • Cardiac HCN channels: Structure, function, and modulation
    • Biel M., Schneider A., Wahl C. Cardiac HCN channels: Structure, function, and modulation. Trends Cardiovasc Med 2002, 12:206-212.
    • (2002) Trends Cardiovasc Med , vol.12 , pp. 206-212
    • Biel, M.1    Schneider, A.2    Wahl, C.3
  • 3
    • 67651030760 scopus 로고    scopus 로고
    • Hyperpolarization-activated cation channels: From genes to function
    • Biel M., Wahl-Schott C., Michalakis S., Zong X. Hyperpolarization-activated cation channels: From genes to function. Physiol Rev 2009, 89:847-885.
    • (2009) Physiol Rev , vol.89 , pp. 847-885
    • Biel, M.1    Wahl-Schott, C.2    Michalakis, S.3    Zong, X.4
  • 5
    • 0019229267 scopus 로고
    • Voltage-clamp investigations of membrane currents underlying pace-maker activity in rabbit sino-atrial node
    • Brown H., Difrancesco D. Voltage-clamp investigations of membrane currents underlying pace-maker activity in rabbit sino-atrial node. J Physiol 1980, 308:331-351.
    • (1980) J Physiol , vol.308 , pp. 331-351
    • Brown, H.1    Difrancesco, D.2
  • 6
    • 33646598103 scopus 로고    scopus 로고
    • I(f) in non-pacemaker cells: Role and pharmacological implications
    • Cerbai E., Mugelli A. I(f) in non-pacemaker cells: Role and pharmacological implications. Pharmacol Res 2006, 53:416-423.
    • (2006) Pharmacol Res , vol.53 , pp. 416-423
    • Cerbai, E.1    Mugelli, A.2
  • 7
    • 26844506839 scopus 로고    scopus 로고
    • The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient
    • Costantini D.L., Arruda E.P., Agarwal P., et al. The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell 2005, 123:347-358.
    • (2005) Cell , vol.123 , pp. 347-358
    • Costantini, D.L.1    Arruda, E.P.2    Agarwal, P.3
  • 8
    • 0032514164 scopus 로고    scopus 로고
    • + channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome
    • + channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome. Circ Res 1998, 83:95-102.
    • (1998) Circ Res , vol.83 , pp. 95-102
    • Drici, M.D.1    Arrighi, I.2    Chouabe, C.3
  • 9
    • 80055010250 scopus 로고    scopus 로고
    • HCN3 contributes to the ventricular action potential waveform in the murine heart
    • Fenske S., Mader R., Scharr A., et al. HCN3 contributes to the ventricular action potential waveform in the murine heart. Circ Res 2011, 109:1015-1023.
    • (2011) Circ Res , vol.109 , pp. 1015-1023
    • Fenske, S.1    Mader, R.2    Scharr, A.3
  • 10
    • 0017681611 scopus 로고
    • Ionic membrane conductance during the time course of the cardiac action potential
    • Goldman Y., Morad M. Ionic membrane conductance during the time course of the cardiac action potential. J Physiol 1977, 268:655-695.
    • (1977) J Physiol , vol.268 , pp. 655-695
    • Goldman, Y.1    Morad, M.2
  • 12
    • 35648939866 scopus 로고    scopus 로고
    • HCN4 provides a "depolarization reserve" and is not required for heart rate acceleration in mice
    • Herrmann S., Stieber J., Stöckl G., et al. HCN4 provides a "depolarization reserve" and is not required for heart rate acceleration in mice. EMBO J 2007, 26:4423-4432.
    • (2007) EMBO J , vol.26 , pp. 4423-4432
    • Herrmann, S.1    Stieber, J.2    Stöckl, G.3
  • 13
    • 0036110328 scopus 로고    scopus 로고
    • Ion channel remodeling in cardiac hypertrophy is prevented by blood pressure reduction without affecting heart weight increase in rats with abdominal aortic banding
    • Hiramatsu M., Furukawa T., Sawanobori T., Hiraoka M. Ion channel remodeling in cardiac hypertrophy is prevented by blood pressure reduction without affecting heart weight increase in rats with abdominal aortic banding. J Cardiovasc Pharmacol 2002, 39:866-874.
    • (2002) J Cardiovasc Pharmacol , vol.39 , pp. 866-874
    • Hiramatsu, M.1    Furukawa, T.2    Sawanobori, T.3    Hiraoka, M.4
  • 14
    • 84865195928 scopus 로고    scopus 로고
    • Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart
    • Hofmann F., Fabritz L., Stieber J., et al. Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart. Cardiovasc Res 2012, 95:317-326.
    • (2012) Cardiovasc Res , vol.95 , pp. 317-326
    • Hofmann, F.1    Fabritz, L.2    Stieber, J.3
  • 15
    • 0031963215 scopus 로고    scopus 로고
    • Hyperpolarization-activated inward current in ventricular myocytes from normal and failing human hearts
    • Hoppe U.C., Jansen E., Südkamp M., Beuckelmann D.J. Hyperpolarization-activated inward current in ventricular myocytes from normal and failing human hearts. Circulation 1998, 97:55-65.
    • (1998) Circulation , vol.97 , pp. 55-65
    • Hoppe, U.C.1    Jansen, E.2    Südkamp, M.3    Beuckelmann, D.J.4
  • 16
    • 0030823390 scopus 로고    scopus 로고
    • Genetically induced reduction in small currents has major impact
    • Kass R.S. Genetically induced reduction in small currents has major impact. Circulation 1997, 96:1720-1721.
    • (1997) Circulation , vol.96 , pp. 1720-1721
    • Kass, R.S.1
  • 17
    • 33847104663 scopus 로고    scopus 로고
    • Direct inhibition of cardiac hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by clonidine
    • Knaus A., Zong X., Beetz N., et al. Direct inhibition of cardiac hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by clonidine. Circulation 2007, 115:872-880.
    • (2007) Circulation , vol.115 , pp. 872-880
    • Knaus, A.1    Zong, X.2    Beetz, N.3
  • 18
    • 0032508040 scopus 로고    scopus 로고
    • A family of hyperpolarization-activated mammalian cation channels
    • Ludwig A., Zong X., Jeglitsch M., et al. A family of hyperpolarization-activated mammalian cation channels. Nature 1998, 393:587-591.
    • (1998) Nature , vol.393 , pp. 587-591
    • Ludwig, A.1    Zong, X.2    Jeglitsch, M.3
  • 19
    • 22844433789 scopus 로고    scopus 로고
    • The murine HCN3 gene encodes a hyperpolarization-activated cation channel with slow kinetics and unique response to cyclic nucleotides
    • Mistrík P., Mader R., Michalakis S., et al. The murine HCN3 gene encodes a hyperpolarization-activated cation channel with slow kinetics and unique response to cyclic nucleotides. J Biol Chem 2005, 280:27056-27061.
    • (2005) J Biol Chem , vol.280 , pp. 27056-27061
    • Mistrík, P.1    Mader, R.2    Michalakis, S.3
  • 20
    • 70349325703 scopus 로고    scopus 로고
    • Is there a significant transmural gradient in repolarization time in the intact heart?. Cellular basis of the T wave: A century of controversy
    • Patel C., Burke J.F., Patel H., et al. Is there a significant transmural gradient in repolarization time in the intact heart?. Cellular basis of the T wave: A century of controversy. Circ Arrhythm Electrophysiol 2009, 2:80-88.
    • (2009) Circ Arrhythm Electrophysiol , vol.2 , pp. 80-88
    • Patel, C.1    Burke, J.F.2    Patel, H.3
  • 21
    • 70349652537 scopus 로고    scopus 로고
    • Transcription profiling of HCN-channel isotypes throughout mouse cardiac development
    • Schweizer P.A., Yampolsky P., Malik R., et al. Transcription profiling of HCN-channel isotypes throughout mouse cardiac development. Basic Res Cardiol 2009, 104:621-629.
    • (2009) Basic Res Cardiol , vol.104 , pp. 621-629
    • Schweizer, P.A.1    Yampolsky, P.2    Malik, R.3
  • 22
    • 48849089617 scopus 로고    scopus 로고
    • Molecular basis of funny current (If) in normal and failing human heart
    • Stillitano F., Lonardo G., Zicha S., et al. Molecular basis of funny current (If) in normal and failing human heart. J Mol Cell Cardiol 2008, 45:289-299.
    • (2008) J Mol Cell Cardiol , vol.45 , pp. 289-299
    • Stillitano, F.1    Lonardo, G.2    Zicha, S.3
  • 23
    • 78649711769 scopus 로고    scopus 로고
    • Pathophysiological remodeling of mouse cardiac myocytes expressing dominant negative mutant of neuron restrictive silencing factor
    • Takano M., Kinoshita H., Shioya T., et al. Pathophysiological remodeling of mouse cardiac myocytes expressing dominant negative mutant of neuron restrictive silencing factor. Circ J 2010, 74:2712-2719.
    • (2010) Circ J , vol.74 , pp. 2712-2719
    • Takano, M.1    Kinoshita, H.2    Shioya, T.3
  • 25
    • 0035980173 scopus 로고    scopus 로고
    • Gender-based differences in cardiac repolarization in mouse ventricle
    • Trépanier-Boulay V., St-Michel C., Tremblay A., Fiset C. Gender-based differences in cardiac repolarization in mouse ventricle. Circ Res 2001, 89:437-444.
    • (2001) Circ Res , vol.89 , pp. 437-444
    • Trépanier-Boulay, V.1    St-Michel, C.2    Tremblay, A.3    Fiset, C.4
  • 26
    • 60749121565 scopus 로고    scopus 로고
    • Role of HCN4 channel in preventing ventricular arrhythmia
    • Ueda K., Hirano Y., Higashiuesato Y., et al. Role of HCN4 channel in preventing ventricular arrhythmia. J Hum Genet 2009, 54:115-121.
    • (2009) J Hum Genet , vol.54 , pp. 115-121
    • Ueda, K.1    Hirano, Y.2    Higashiuesato, Y.3
  • 27
    • 49249098962 scopus 로고    scopus 로고
    • Mathematical model of the neonatal mouse ventricular action potential
    • Wang L.J., Sobie E.A. Mathematical model of the neonatal mouse ventricular action potential. Am J Physiol Heart Circ Physiol 2008, 294:H2565-H2575.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Wang, L.J.1    Sobie, E.A.2
  • 28
    • 70449162341 scopus 로고
    • Resting and action potentials of cardiac muscle
    • Weidmann S. Resting and action potentials of cardiac muscle. Ann N Y Acad Sci 1957, 65:663-678.
    • (1957) Ann N Y Acad Sci , vol.65 , pp. 663-678
    • Weidmann, S.1
  • 29
    • 73049141695 scopus 로고
    • Membrane excitation in cardiac muscle
    • Weidmann S. Membrane excitation in cardiac muscle. Circulation 1961, 24:499-505.
    • (1961) Circulation , vol.24 , pp. 499-505
    • Weidmann, S.1
  • 30
    • 0033567165 scopus 로고    scopus 로고
    • Elimination of the transient outward current and action potential prolongation in mouse atrial myocytes expressing a dominant negative Kv4 alpha subunit
    • Xu H., Li H., Nerbonne J.M. Elimination of the transient outward current and action potential prolongation in mouse atrial myocytes expressing a dominant negative Kv4 alpha subunit. J Physiol 1999, 519:11-21.
    • (1999) J Physiol , vol.519 , pp. 11-21
    • Xu, H.1    Li, H.2    Nerbonne, J.M.3
  • 31
    • 0032480801 scopus 로고    scopus 로고
    • Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome
    • Yan G.X., Antzelevitch C. Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome. Circulation 1998, 98:1928-1936.
    • (1998) Circulation , vol.98 , pp. 1928-1936
    • Yan, G.X.1    Antzelevitch, C.2
  • 32
    • 24144476557 scopus 로고    scopus 로고
    • Effect of input resistance voltage-dependency on DC estimate of membrane capacitance in cardiac myocytes
    • Zaniboni M., Cacciani F., Groppi M. Effect of input resistance voltage-dependency on DC estimate of membrane capacitance in cardiac myocytes. Biophys J 2005, 89:2170-2181.
    • (2005) Biophys J , vol.89 , pp. 2170-2181
    • Zaniboni, M.1    Cacciani, F.2    Groppi, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.