In vitro bioaccessibility of coenzyme Q10 in enriched yoghurts

International Journal of Food Science and Technology

Volumn 47, Issue 9, 2012, Pages 1986-1992

  Ercan, Pidotlessnar ^a   El, Sedef Nehir ^a  

^a EGE UNIVERSITY   (Turkey)

Author keywords

cyclodextrin coenzyme Q10 complex; Bioaccessibility; Coenzyme Q10; Enrichment; Nanoparticle coenzyme Q10

Indexed keywords

BIOACCESSIBILITY; COENZYME Q10; IN-CONTROL; IN-VITRO; SKIM MILKS; SPHERICAL SHAPE;

BLAST ENRICHMENT; EMULSIFICATION;

NANOPARTICLES;

EID: 84865185507     PISSN: 09505423     EISSN: 13652621     Source Type: Journal    
DOI: 10.1111/j.1365-2621.2012.03061.x     Document Type: Article

References (33)

1. Ankola, D.D., Viswanad, B., Bhardwaj, V., Ramarao, P. & Kumar, M.N.V.R. (2007). Development of potent oral nanoparticulate formulation of coenzyme Q10 for treatment of hypertension: can the simple nutritional supplements be used as first line therapeutic agents for prophylaxis/therapy? European Journal of Pharmaceutics and Biopharmaceutics, 67, 361-369.
2. AOAC (1995). Official Methods of Analyses, 16th edn. Washington, DC: Association of Official Agricultural Chemists.
3. Bala, I., Bharadwaj, V., Hariharan, S., Sitterberg, J., Bakowsky, U. & Kumar, M.N.V.R. (2005). Design of biodegradable nanoparticles: a novel approach to encapsulating poorly soluble phytochemical ellagic acid. Nanotechnology, 16, 2819-2822.
4. Bhagavan, H.N., Chopra, R.K., Craft, N.E., Chitchumroonchokchai, C. & Failla, M.L. (2007). Assessment of coenzyme Q10 absorption using an in vitro digestion-Caco-2 cell model. International Journal of Pharmaceutics, 333, 112-117.
5. Crane, F.L. (2001). Biochemical functions of coenzyme Q10. Journal of the American College of Nutrition, 20, 591-598.
6. Ercan, P. & El, S.N. (2011). Changes in content of coenzyme Q10 in beef muscle, beef liver and beef heart with cooking and in vitro digestion. Journal of Food Composition and Analysis, 24, 1136-1140.
7. Esmaeili, F., Hosseini-Nasr, M., Rad-Malekshahi, M., Samadi, N., Atyabi, F. & Dinarvand, R. (2007). Preparation and antibacterial activity evaluation of rifampicin-loaded poly lactide-co-glycolide nanoparticles. Clinical Nanomedicine. Nanomedicine: Nanotechnology, Biology, and Medicine, 3, 161-167.
8. Esmaeili, F., Atyabi, F. & Dinarvand, R. (2008a). Preparation and characterization of estradiol-loaded PLGA nanoparticles using homogenization-solvent diffusion method. DARU, 16, 196-202.
9. Esmaeili, F., Ghahremani, M.H., Esmaeili, B., Khoshayand, M.R., Atyabi, F. & Dinarvand, R. (2008b). PLGA nanoparticles of different surface properties: preparation and evaluation of their body distribution. Pharmaceutical Nanotechnology. International Journal of Pharmaceutics, 349, 249-255.
10. Fir, M., Šmidovnik, A., Wondra, A.G., Žmitek, J., Prošek, M. & Milivojevič, L. (2006). Quantitative determination of Coenzyme Q10 in kefir and yogurt. 12th International Symposium on Separation Sciences, 171, Lipica, Slovenia.
11. Hariharan, S., Bhardwaj, V., Bala, I., Sitterberg, J., Bakowsky, U. & Kumar, M.N.V.R. (2006). Design of estradiol loaded PLGA nanoparticle formulations: a potential oral delivery system for hormone therapy. Pharmaceutical Research, 23, 184-195.
12. Hu, X., Guo, Y., Wang, L., Hua, D., Hong, Y. & Li, J. (2011). Coenzyme Q10 nanoparticles prepared by a supercritical fluid-based method. The Journal of Supercritical Fluids, 57, 66-72.
13. Itagaki, S., Ochiai, A., Kobayashi, M., Sugawara, M., Hirano, T. & Iseki, K. (2010). Grapefruit juice enhance the uptake of coenzyme Q10 in the human intestinal cell-line Caco-2. Food Chemistry, 120, 552-555.
14. Kagan, V.E. & Quinn, P.T. (2001). Coenzyme Q: Molecular Mechanisms in Health and Disease. Boca Raton, FL: CRC Press.
15. Kubo, H., Fujii, K., Kawabe, T., Matsumoto, S., Kishida, H. & Hosoe, K. (2008). Food content of ubiquinol-10 and ubiquinone-10 in the Japanese diet. Journal of Food Composition and Analysis, 21, 199-210.
16. Mason, P. (2005). Potential uses for coenzyme Q10. The Pharmaceutical Journal, 275, 379-382.
17. Mattila, P. & Kumpulainen, J. (2001). Coenzyme Q9 and Q10: contents in foods and dietary intake. Journal of Food Composition and Analysis, 14, 409-417.
18. McClements, D.J. (2010). Design of nano-laminated coatings to control bioavailability of lipophilic food components. Journal of Food Science, 75, 30-42.
19. Moldenhauer, J. & Jan, C. (2005). Method for producing a coenzyme Q10/γ-cyclodextrin complex. US Patent 6861447.
20. Nehilla, B.J., Bergkvist, M., Popat, K.C. & Desai, T.A. (2008). Purified and surfactant-free coenzyme Q10-loaded biodegradable nanoparticles. Pharmaceutical Nanotechnology. International Journal of Pharmaceutics, 348, 107-114.
21. Overvad, K., Diamant, B., Holm, L., Hùlmer, G., Mortensen, S.A. & Stender, S. (1999). Review coenzyme Q10 in health and disease. European Journal of Clinical Nutrition, 53, 764-770.
22. Ozaki, A., Muromachi, A., Sumi, M., Sakai, Y., Morishita, K. & Okamoto, T. (2010). Emulsification of coenzyme Q(10) using gum arabic increases bioavailability in rats and human and improves food-processing suitability. Journal of Nutritional Science and Vitaminology, 56, 41-47.
23. Palzer, S. (2009). Food structures for nutrition, health and wellness. Trends Food Science and Techonology, 20, 194-200.
24. Parkhideh, D. (2008). Methods and compositions that enhance bioavailability of coenzyme-Q10. United States Patent 7, 438, 903, October 21.
25. Prada, J. & Aguilera, J.M. (2007). Food microstructure affects the bioavailability of several nutrients. Journal Food Science, 72, 21-31.
26. Pravst, I., Prošek, M., Wondra, A.G., Žmitek, K. & Žmitek, J. (2009). The stability of coenzyme Q10 in fortified foods. Acta Chime Slovenia, 56, 953-958.
27. Pravst, I., Žmitek, K. & Žmitek, J. (2010). Coenzyme Q10 contents in foods and fortification strategies. Critical Reviews in Food Science and Nutrition, 50, 269-280.
28. Swarnakar, N.K., Jain, A.K., Singh, R.P., Godugu, C., Das, M. & Jain, S. (2011). Oral bioavailability, therapeutic efficacy and reactive oxygen species scavenging properties of coenzyme Q10-loaded polymeric nanoparticles. Biomaterials, 32, 6860-6874.
29. Thanatuksorn, P., Kawai, K., Hayakawa, M., Hayashi, M. & Kajiwara, K. (2009). Improvement of the oral bioavailability of coenzyme Q10 by emulsification with fats and emulsifiers used in the food industry. LWT - Food Science and Technology, 42, 385-390.
30. Turkish Food Codex Communiqué on Fermented Milk Products. (2009). Communiqué No: 2009-25. Agriculture and Rural Affairs Minister, Ankara.
31. Ubbink, J. & Krüger, J. (2006). Physical approaches for the delivery of active ingredients in foods. Trends Food Science and Technology, 17, 244-254.
32. 10 in the diet-daily intake and relative bioavailability. Molecular Aspects of Medicine, 18, 251-254.
33. Žmitek, J., Žmitek, K. & Pravst, I. (2008). Improving the bioavailability of coenzyme Q10 from theory to practice. AgroFOOD Industry Hi-Tech, 19, 8-10.