Comparative in vitro efficacies of ethanol-, EDTA- and levofloxacin-based catheter lock solutions on eradication of Stenotrophomonas maltophilia biofilms

Journal of Medical Microbiology

Volumn 61, Issue PART 9, 2012, Pages 1248-1253

  de Rossi, Beatriz Passerini ^a   Feldman, Laureana ^a   Pineda, María Saliba ^a   Vay, Carlos ^b   Franco, Mirta ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b HOSPITAL DE CLÍNICAS JOSÉ DE SAN MARTÍN   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CHELATING AGENT; EDETIC ACID; LEVOFLOXACIN; SILICONE;

ARGENTINA; ARTICLE; BACTERIAL COUNT; BACTERIAL GROWTH; BACTERIAL SURVIVAL; BACTERIAL VIABILITY; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATION; BIOFILM; CATHETER CARE; CATHETER INFECTION; COMPARATIVE EFFECTIVENESS; DISINFECTION; ERADICATION THERAPY; IN VITRO STUDY; LIMIT OF DETECTION; NONHUMAN; PRIORITY JOURNAL; STENOTROPHOMONAS MALTOPHILIA;

ANTI-BACTERIAL AGENTS; ARGENTINA; BACTEREMIA; BIOFILMS; CATHETER-RELATED INFECTIONS; CATHETERS, INDWELLING; CHELATING AGENTS; COLONY COUNT, MICROBIAL; EDETIC ACID; ETHANOL; HOSPITALS, UNIVERSITY; HUMANS; MICROBIAL SENSITIVITY TESTS; OFLOXACIN; SOLUTIONS; STENOTROPHOMONAS MALTOPHILIA;

EID: 84865184600     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.039743-0     Document Type: Article

References (25)

1. Balestrino, D., Souweine, B., Charbonnel, N., Lautrette, A., Aumeran, C., Traoré, O. & Forestier, C. (2009). Eradication of microorganisms embedded in biofilm by an ethanol-based catheter lock solution. Nephrol Dial Transplant 24, 3204-3209.
2. Bleyer, A. J., Mason, L., Russell, G., Raad, I. I. & Sherertz, R. J. (2005). A randomized, controlled trial of a new vascular catheter flush solution (minocycline-EDTA) in temporary hemodialysis access. Infect Control Hosp Epidemiol 26, 520-524.
3. Bookstaver, P. B., Gerrald, K. R. & Moran, R. R. (2010). Clinical outcomes of antimicrobial lock solutions used in a treatment modality: a retrospective case series analysis. Clin Pharmacol 2, 123-130.
4. Broom, J., Woods, M., Allworth, A., McCarthy, J., Faoagali, J., Macdonald, S. & Pithie, A. (2008). Ethanol lock therapy to treat tunnelled central venous catheter-associated blood stream infections: results from a prospective trial. Scand J Infect Dis 40, 399-406.
5. Broom, J. K., O'Shea, S., Govindarajulu, S., Playford, E. G., Hawley, C. M., Isbel, N. M., Campbell, S. B., Mudge, D. W., Carpenter, S. & other authors (2009). Rationale and design of the HEALTHY-CATH trial: a randomised controlled trial of Heparin versus EthAnol Lock THerapY for the prevention of Catheter Associated infecTion in Haemodialysis patients. BMC Nephrol 10, 23.
6. Chambers, S. T., Peddie, B. & Pithie, A. (2006). Ethanol disinfection of plastic-adherent micro-organisms. J Hosp Infect 63, 193-196.
7. Cober, M. P., Kovacevich, D. S. & Teitelbaum, D. H. (2011). Ethanollock therapy for the prevention of central venous access device infections in pediatric patients with intestinal failure. JPEN J Parenter Enteral Nutr 35, 67-73.
8. Crossman, L. C., Gould, V. C., Dow, J. M., Vernikos, G. S., Okazaki, A., Sebaihia, M., Saunders, D., Arrowsmith, C., Carver, T. & other authors (2008). The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants. Genome Biol 9, R74.
9. Dannenberg, C., Bierbach, U., Rothe, A., Beer, J. & Körholz, D. (2003). Ethanol-lock technique in the treatment of bloodstream infections in pediatric oncology patients with broviac catheter. J Pediatr Hematol Oncol 25, 616-621.
10. Denton, M. & Kerr, K. G. (1998). Microbiological and clinical aspects of infection associated with Stenotrophomonas maltophilia. Clin Microbiol Rev 11, 57-80.
11. Donlan, R. M. (2011). Biofilm elimination on intravascular catheters: important considerations for the infectious disease practitioner. Clin Infect Dis 52, 1038-1045.
12. Fernandez-Hidalgo, N., Almirante, B., Calleja, R., Ruiz, I., Planes, A. M., Rodriguez, D., Pigrau, C. & Pahissa, A. (2006). Antibiotic-lock therapy for long-term intravascular catheter-related bacteraemia: results of an open, non-comparative study. J Antimicrob Chemother 57, 1172-1180.
13. Maiefski, M., Rupp, M. E. & Hermsen, E. D. (2009). Ethanol lock technique: review of the literature. Infect Control Hosp Epidemiol 30, 1096-1108.
14. Mermel, L. A., Allon, M., Bouza, E., Craven, D. E., Flynn, P., O'Grady, N. P., Raad, I. I., Rijnders, B. J., Sherertz, R. J. & Warren, D. K. (2009). Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 49, 1-45.
15. Mouw, E., Chessman, K., Lesher, A. & Tagge, E. (2008). Use of an ethanol lock to prevent catheter-related infections in children with short bowel syndrome. J Pediatr Surg 43, 1025-1029.
16. Onland, W., Shin, C. E., Fustar, S., Rushing, T. & Wong, W. Y. (2006). Ethanol-lock technique for persistent bacteremia of long-term intravascular devices in pediatric patients. Arch Pediatr Adolesc Med 160, 1049-1053.
17. Passerini de Rossi, B., Calenda, M., Vay, C. & Franco, M. (2007). Biofilm formation by Stenotrophomonas maltophilia isolates from device-associated nosocomial infections. Rev Argent Microbiol 39, 204-212.
18. Passerini de Rossi, B., Garci{dotless}́a, C., Calenda, M., Vay, C. & Franco, M. (2009). Activity of levofloxacin and ciprofloxacin on biofilms and planktonic cells of Stenotrophomonas maltophilia isolates from patients with device-associated infections. Int J Antimicrob Agents 34, 260-264.
19. Poole, C. V., Carlton, D., Bimbo, L. & Allon, M. (2004). Treatment of catheter-related bacteraemia with an antibiotic lock protocol: effect of bacterial pathogen. Nephrol Dial Transplant 19, 1237-1244.
20. Qu, Y., Istivan, T. S., Daley, A. J., Rouch, D. A. & Deighton, M. A. (2009). Comparison of various antimicrobial agents as catheter lock solutions: preference for ethanol in eradication of coagulase-negative staphylococcal biofilms. J Med Microbiol 58, 442-450.
21. Raad, I., Hanna, H., Dvorak, T., Chaiban, G. & Hachem, R. (2007). Optimal antimicrobial catheter lock solution, using different combinations of minocycline, EDTA, and 25-percent ethanol, rapidly eradicates organisms embedded in biofilm. Antimicrob Agents Chemother 51, 78-83.
22. Sanders, J., Pithie, A., Ganly, P., Surgenor, L., Wilson, R., Merriman, E., Loudon, G., Judkins, R. & Chambers, S. (2008). A prospective doubleblind randomized trial comparing intraluminal ethanol with heparinized saline for the prevention of catheter-associated bloodstream infection in immunosuppressed haematology patients. J Antimicrob Chemother 62, 809-815.
23. Sherertz, R. J., Boger, M. S., Collins, C. A., Mason, L. & Raad, I. I. (2006). Comparative in vitro efficacies of various catheter lock solutions. Antimicrob Agents Chemother 50, 1865-1868.
24. Takla, T. A., Zelenitsky, S. A. & Vercaigne, L. M. (2008). Effectiveness of a 30% ethanol/4% trisodium citrate locking solution in preventing biofilm formation by organisms causing haemodialysis catheterrelated infections. J Antimicrob Chemother 62, 1024-1026.
25. Vanholder, R., Canaud, B., Fluck, R., Jadoul, M., Labriola, L., Marti-Monros, A., Tordoir, J. & Van Biesen, W. (2010). Diagnosis, prevention and treatment of haemodialysis catheter-related bloodstream infections (CRBSI): a position statement of European Renal Best Practice (ERBP). NDT Plus 3, 234-246.